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TUBGCP3
Gamma-tubulin complex component 3 is a protein that in humans is encoded by the ''TUBGCP3'' gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. See also *Tubulin * TUBGCP2 * TUBGCP4 * TUBGCP5 * TUBGCP6 Gamma-tubulin complex component 6 is a protein that in humans is encoded by the ''TUBGCP6'' gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. See also * Tubulin * TUBGCP2 * TUBGCP3 * TUB ... References Further reading * * * * * * {{gene-13-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tubulin
Tubulin in molecular biology can refer either to the tubulin protein superfamily of globular proteins, or one of the member proteins of that superfamily. α- and β-tubulins polymerize into microtubules, a major component of the eukaryotic cytoskeleton. Microtubules function in many essential cellular processes, including mitosis. Tubulin-binding drugs kill cancerous cells by inhibiting microtubule dynamics, which are required for DNA segregation and therefore cell division. In eukaryotes, there are six members of the tubulin superfamily, although not all are present in all species.Turk E, Wills AA, Kwon T, Sedzinski J, Wallingford JB, Stearns "Zeta-Tubulin Is a Member of a Conserved Tubulin Module and Is a Component of the Centriolar Basal Foot in Multiciliated Cells"Current Biology (2015) 25:2177-2183. Both α and β tubulins have a mass of around 50 kDa and are thus in a similar range compared to actin (with a mass of ~42 kDa). In contrast, tubulin polymers (microtubules) ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TUBGCP2
Gamma-tubulin complex component 2 is a protein that in humans is encoded by the ''TUBGCP2'' gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. See also *Tubulin * TUBGCP3 * TUBGCP4 * TUBGCP5 * TUBGCP6 Gamma-tubulin complex component 6 is a protein that in humans is encoded by the ''TUBGCP6'' gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. See also * Tubulin * TUBGCP2 * TUBGCP3 * TUB ... References Further reading * * * * * * * * * * * {{gene-10-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TUBGCP4
Tubulin, gamma complex associated protein 4 is a protein in humans that is encoded by the TUBGCP4 gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. See also *Tubulin * TUBGCP2 * TUBGCP3 * TUBGCP5 * TUBGCP6 Gamma-tubulin complex component 6 is a protein that in humans is encoded by the ''TUBGCP6'' gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. See also * Tubulin * TUBGCP2 * TUBGCP3 * TUB ... References Further reading * * * * * {{gene-15-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TUBGCP5
Gamma-tubulin complex component 5 is a protein that in humans is encoded by the ''TUBGCP5'' gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. See also *Tubulin * TUBGCP2 * TUBGCP3 * TUBGCP4 * TUBGCP6 Gamma-tubulin complex component 6 is a protein that in humans is encoded by the ''TUBGCP6'' gene. It is part of the gamma tubulin complex, which required for microtubule nucleation at the centrosome. See also * Tubulin * TUBGCP2 * TUBGCP3 * TUB ... References Further reading * * * * * * * {{gene-15-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residues. Proteins perform a vast array of functions within organisms, including catalysing metabolic reactions, DNA replication, responding to stimuli, providing structure to cells and organisms, and transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the nucleotide sequence of their genes, and which usually results in protein folding into a specific 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called peptides. The individual amino acid residues are bonded together by peptide bonds and adjacent amino acid residues. The sequence of amino acid resid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene (from , ; "... Wilhelm Johannsen coined the word gene to describe the Mendelian units of heredity..." meaning ''generation'' or ''birth'' or ''gender'') can have several different meanings. The Mendelian gene is a basic unit of heredity and the molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and noncoding genes. During gene expression, the DNA is first copied into RNA. The RNA can be directly functional or be the intermediate template for a protein that performs a function. The transmission of genes to an organism's offspring is the basis of the inheritance of phenotypic traits. These genes make up different DNA sequences called genotypes. Genotypes along with environmental and developmental factors determine what the phenotypes will be. Most biological traits are under the influence of polygenes (many different genes) as well as g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microtubule Nucleation In cell biology, microtubule nucleation is the event that initiates '' de novo'' formation of microtubules (MTs). These filaments of the cytoskeleton typically form through polymerization of α- and β-tubulin dimers, the basic building blocks of the microtubule, which initially inte |
