TETS (other)
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TETS (other)
TETS may refer to one of the following: * Tetramethylenedisulfotetramine * Trains Entering Terminal Stations, a train protection system * TETs, a transliteration of the Russian term for cogeneration power stations as seen in station names See also * Tet (other) {{Disambiguation ...
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Tetramethylenedisulfotetramine
Tetramethylenedisulfotetramine (TETS) is an organic compound used as a rodenticide (rat poison). It is an odorless, tasteless white powder that is slightly soluble in water, DMSO and acetone, and insoluble in methanol and ethanol. It is a sulfamide derivative. It can be synthesized by reacting sulfamide with formaldehyde solution in acidified water. When crystallized from acetone, it forms cubic crystals with a melting point of 255–260 °C. Toxicity and mechanism TETS is a neurotoxin and convulsant, causing lethal convulsions. Its effect is similar to but stronger than picrotoxin, a GABA-A receptor antagonist widely used in research. As one of the most hazardous pesticides, it is 100 times more toxic than potassium cyanide. TETS binds to neuronal GABA gated chloride channels, often causing status epilepticus. No antidote is known. The lethal dose for humans is 7–10 mg. Poisoning is diagnosed by GC-MS and the treatment is mainly supportive, with large IV doses of a b ...
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Trains Entering Terminal Stations
The Moorgate tube crash occurred on 28 February 1975 at 8:46 am on the London Underground's Northern City Line; 43 people died and 74 were injured after a train failed to stop at the line's southern terminus, Moorgate station, and crashed into its end wall. It is considered the worst peacetime accident on the London Underground. No fault was found with the train, and the inquiry by the Department of the Environment concluded that the accident was caused by the actions of Leslie Newson, the 56-year-old driver. The crash forced the first carriage into the roof of the tunnel at the front and back, but the middle remained on the trackbed; the coach was crushed to . The second carriage was concertinaed at the front as it collided with the first, and the third rode over the rear of the second. The brakes were not applied and the dead man's handle was still depressed when the train crashed. It took 13 hours to remove the injured, many of whom had to be cut free from the wrecka ...
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