TDI-11861
TDI-11861 is a chemical compound which acts as a potent and selective inhibitor of soluble adenylyl cyclase (sAC). In animal studies it reversibly inhibits sperm motility, producing temporary infertility without hormonal side effects. While TDI-11861 is at an early developmental stage and is unlikely to be developed for medical uses in humans itself, it represents an important proof of concept which may potentially lead to the development of future male contraceptive drugs. See also * CDD-2807 * JQ1 * YCT529 YCT529 is a drug which acts as a potent and selective antagonist of the Vitamin A receptor retinoic acid receptor alpha (RAR-α). In studies on mice it produced a 99% reduction in sperm production, and it has proceeded to early stage human clini ... References {{pharm-stub Chloroarenes Pyrimidines Morpholines Pyrazoles Difluoromethyl compounds ...
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