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Susan Lindquist
Susan Lee Lindquist, ForMemRS (June 5, 1949 – October 27, 2016) was an American professor of biology at MIT specializing in molecular biology, particularly the protein folding problem within a family of molecules known as heat-shock proteins, and prions. Lindquist was a member and former director of the Whitehead Institute and was awarded the National Medal of Science in 2010. Early life and education Lindquist was born in Chicago, Illinois, to Iver and Eleanor (née Maggio), and attended Maine South High School in Park Ridge. Lindquist's father and mother were of Swedish and Italian descent, respectively, and although they expected her to become a housewife, Susan studied microbiology at the University of Illinois as an undergraduate and received her PhD in biology from Harvard University in 1976. She completed a post-doctoral fellowship at the American Cancer Society. Career Upon completing her dissertation in 1976, Lindquist moved to the University of Chicago for a sh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Royal Society
The Royal Society, formally The Royal Society of London for Improving Natural Knowledge, is a learned society and the United Kingdom's national academy of sciences. The society fulfils a number of roles: promoting science and its benefits, recognising excellence in science, supporting outstanding science, providing scientific advice for policy, education and public engagement and fostering international and global co-operation. Founded on 28 November 1660, it was granted a royal charter by Charles II of England, King Charles II and is the oldest continuously existing scientific academy in the world. The society is governed by its Council, which is chaired by the society's president, according to a set of statutes and standing orders. The members of Council and the president are elected from and by its Fellows, the basic members of the society, who are themselves elected by existing Fellows. , there are about 1,700 fellows, allowed to use the postnominal title FRS (Fellow ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Medal Of Science
The National Medal of Science is an honor bestowed by the President of the United States to individuals in science and engineering who have made important contributions to the advancement of knowledge in the fields of behavioral science, behavioral and social sciences, biology, chemistry, engineering, mathematics and physics. The twelve member presidential Committee on the National Medal of Science is responsible for selecting award recipients and is administered by the National Science Foundation (NSF). It is the highest science award in the United States. History The National Medal of Science was established on August 25, 1959, by an act of the Congress of the United States under . The medal was originally to honor scientists in the fields of the "physical, biological, mathematical, or engineering sciences". The Committee on the National Medal of Science was established on August 23, 1961, by Executive order (United States), executive order 10961 of President John F. Kennedy. O ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Broad Institute
The Eli and Edythe L. Broad Institute of MIT and Harvard (IPA: , pronunciation respelling: ), often referred to as the Broad Institute, is a biomedical and genomic research center located in Cambridge, Massachusetts, United States. The institute is independently governed and supported as a 501(c)(3) nonprofit research organization under the name Broad Institute Inc., and it partners with the Massachusetts Institute of Technology, Harvard University, and the five Harvard teaching hospitals. History The Broad Institute evolved from a decade of research collaborations among MIT and Harvard scientists. One cornerstone was the Center for Genome Research of Whitehead Institute at MIT. Founded in 1982, the Whitehead became a major center for genomics and the Human Genome Project. As early as 1995, scientists at the Whitehead started pilot projects in genomic medicine, forming an unofficial collaborative network among young scientists interested in genomic approaches to cancer and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Whitehead Institute For Biomedical Research
Whitehead may refer to: * Whitehead (comedo), a blocked sweat/sebaceous duct of the skin * Whitehead (bird), a small species of passerine bird, endemic to New Zealand * Whitehead building, heritage listed residence of the principal of the University of Adelaide's Lincoln College * Whitehead (patience), a patience game related to Klondike * Whitehead (surname) * Whitehead & Co., a former torpedo company founded by Robert Whitehead in 1875 * Whitehead SpA, one of the names of the later torpedo factory in Livorno * Whiteheads, another name for the wheat disease take-all * USS ''Whitehead'' (1861–1865), American Civil War, 136-ton screw steam gunboat Places * Canada: ** Rural Municipality of Whitehead, Manitoba ** Whitehead, Nova Scotia, on Tor Bay * Hong Kong ** Whitehead, Hong Kong, a cape at Wu Kai Sha * Northern Ireland ** Whitehead, County Antrim, a small town in Northern Ireland * United States: ** Lake Whitehead, a reservoir in Napa County, California Napa Co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prion Proteins
The major prion protein (PrP) is encoded in the human body by the ''PRNP'' gene also known as CD230 (cluster of differentiation 230). Expression of the protein is most predominant in the nervous system but occurs in many other tissues throughout the body. The protein can exist in multiple isoforms: the normal PrPC form, and the protease-resistant form designated PrPRes such as the disease-causing PrPSc (scrapie) and an isoform located in mitochondria. The misfolded version PrPSc is associated with a variety of cognitive disorders and neurodegenerative diseases such as in animals: ovine scrapie, bovine spongiform encephalopathy (BSE, mad cow disease), feline spongiform encephalopathy, transmissible mink encephalopathy (TME), exotic ungulate encephalopathy, chronic wasting disease (CWD) which affects deer; and in humans: Creutzfeldt–Jakob disease (CJD), fatal familial insomnia (FFI), Gerstmann–Sträussler–Scheinker syndrome (GSS), kuru, and variant Creutzfeldt–Jakob di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Howard Hughes Medical Institute
The Howard Hughes Medical Institute (HHMI) is an American non-profit medical research organization headquartered in Chevy Chase, Maryland with additional facilities in Ashburn, Virginia. It was founded in 1953 by Howard Hughes, an American business magnate, investor, record-setting pilot, engineer, film director, and philanthropist, known during his lifetime as one of the most financially successful individuals in the world. It is one of the largest private funding organizations for biological and medical research in the United States. HHMI spends about $1 million per HHMI Investigator per year, which amounts to annual investment in biomedical research of about $825 million. The institute has an endowment of $22.6 billion, making it the second-wealthiest philanthropic organization in the United States and the second-best-endowed medical research foundation in the world. HHMI is the former owner of the Hughes Aircraft Company, an American aerospace firm that was divested to vari ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saccharomyces Cerevisiae
''Saccharomyces cerevisiae'' () (brewer's yeast or baker's yeast) is a species of yeast (single-celled fungal microorganisms). The species has been instrumental in winemaking, baking, and brewing since ancient times. It is believed to have been originally isolated from the skin of grapes. It is one of the most intensively studied eukaryotic model organisms in molecular and cell biology, much like '' Escherichia coli'' as the model bacterium. It is the microorganism which causes many common types of fermentation. ''S. cerevisiae'' cells are round to ovoid, 5–10 μm in diameter. It reproduces by budding. Many proteins important in human biology were first discovered by studying their homologs in yeast; these proteins include cell cycle proteins, signaling proteins, and protein-processing enzymes. ''S. cerevisiae'' is currently the only yeast cell known to have Berkeley bodies present, which are involved in particular secretory pathways. Antibodies again ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heat Shock Protein
Heat shock proteins (HSPs) are a family of proteins produced by cells in response to exposure to stressful conditions. They were first described in relation to heat shock, but are now known to also be expressed during other stresses including exposure to cold, UV light and during wound healing or tissue remodeling. Many members of this group perform chaperone functions by stabilizing new proteins to ensure correct folding or by helping to refold proteins that were damaged by the cell stress. This increase in expression is transcriptionally regulated. The dramatic upregulation of the heat shock proteins is a key part of the heat shock response and is induced primarily by heat shock factor (HSF). HSPs are found in virtually all living organisms, from bacteria to humans. Heat shock proteins are named according to their molecular weight. For example, Hsp60, Hsp70 and Hsp90 (the most widely studied HSPs) refer to families of heat shock proteins on the order of 60, 70 and 90 kilo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Cancer Society
The American Cancer Society (ACS) is a nationwide non-profit organization dedicated to eliminating cancer. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and '' Cancer Cytopathology''. History The society was founded on May 22, 1913, by ten physicians and five businessmen in New York City under the name "American Society for the Control of Cancer" (ASCC). The current name was adopted in 1944. At the time of founding, it was not considered appropriate to mention the word "cancer" in public and information concerning this illness was cloaked in a climate of fear and denial. The top item on the founders' agenda was to raise awareness of cancer, before any other progress could be made in funding research. Therefore, a frenetic writing campaign was undertaken to educate doctors, nurses, patients and family members about cancer. Articles were written for popular magazines and professional journals. The ASCC undertook to publish their own journal, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Park Ridge, Illinois
Park Ridge is a city in Cook County, Illinois, United States, and a suburb of Chicago. Per the 2020 United States census, 2020 census, the population was 39,656. It is located north of downtown Chicago. It is close to O'Hare International Airport, major expressways, and rail transportation. It is a part of the Chicago metropolitan area, bordering three official neighborhoods on Chicago's Community areas of Chicago#Far North-West side, Far Northwest Side (Edison Park, Chicago, Edison Park, Norwood Park, Chicago, Norwood Park, and O'Hare, Chicago, O'Hare.) The soil is abundant with clay deposits, which made it a brick-making center for the developing city of Chicago. Park Ridge was originally called Pennyville to honor George Penny, the businessman who owned the local brickyard along with Robert Meacham. Later it was named Brickton. The Des Plaines River divides Park Ridge from neighboring Des Plaines, Illinois, Des Plaines, which is west of Park Ridge. Chicago is south and east o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Maine South High School
Maine South High School (officially known as Maine Township High School South) is a public four-year high school located in Park Ridge, Illinois, United States, a northwest suburb of Chicago. It is part of Maine Township High School District 207. Maine South is well known for its academic, athletic, and fine arts success. Since at least 1992, it has also received mention in national media as the alma mater of Hillary Clinton, a member of the school's first graduating class. History Bids on the construction of Maine South opened on March 18, 1963. Maine South was built in 1964 on the grounds of a former landfill to meet the growing educational needs of the area, mainly the city of Park Ridge, but also some of Niles, Illinois, Niles, Harwood Heights, Illinois, Harwood Heights, Norridge, Illinois, Norridge, and unincorporated Chicago, Illinois, Chicago. The first principal, Clyde Watson, was appointed in December 1963, in order to give him time to begin forming the first parents a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
YouTube
YouTube is an American social media and online video sharing platform owned by Google. YouTube was founded on February 14, 2005, by Steve Chen, Chad Hurley, and Jawed Karim who were three former employees of PayPal. Headquartered in San Bruno, California, it is the second-most-visited website in the world, after Google Search. In January 2024, YouTube had more than 2.7billion monthly active users, who collectively watched more than one billion hours of videos every day. , videos were being uploaded to the platform at a rate of more than 500 hours of content per minute, and , there were approximately 14.8billion videos in total. On November 13, 2006, YouTube was purchased by Google for $1.65 billion (equivalent to $ billion in ). Google expanded YouTube's business model of generating revenue from advertisements alone, to offering paid content such as movies and exclusive content produced by and for YouTube. It also offers YouTube Premium, a paid subs ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
