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Steven L. Mandel
Steven L. Mandel is an American anesthesiologist and advocate for the use of ketamine in the treatment of mental health. Career Mandel is an anesthesiologist, who began his career working in cosmetic surgery offices in California. Following the death of a family member to suspected suicide, anxiety and PTSD he went on to co-found Ketamine Clinics Los Angeles, which he established in 2013. At his clinic, Mandel administers sub-anesthetic doses of ketamine for patients with chronic depression, suicidal ideation, via intravenous infusions. He has also advocated for scientific inquiry into other psychedelics and their potential use as mental health treatments. He is also the founder and first president of the American Society of Ketamine Physicians, Psychotherapists and Practitioners (ASKP3). Education Mandel received a graduate degree in psychology from the University of Cincinnati Graduate School, his MD from the University of Southern California Keck School of Medicine, and did res ...
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Ketamine
Ketamine is a dissociative anesthetic used medically for induction and maintenance of anesthesia. It is also used as a recreational drug. It is one of the safest anesthetics, as, in contrast with opiates, ether, and propofol, it suppresses neither respiration nor heart rate. Ketamine is also simple to administer and highly tolerable compared to drugs with similar effects which are flammable, irritating, or even explosive. Ketamine is a novel compound, derived from PCP, created in pursuit of a safer anesthetic with similar characteristics. Ketamine is also used for acute pain management. At anesthetic doses, ketamine induces a state of "dissociative anesthesia", a trance-like state providing pain relief, sedation, and amnesia. The distinguishing features of ketamine anesthesia are preserved breathing and airway reflexes, stimulated heart function with increased blood pressure, and moderate bronchodilation. At lower, sub-anesthetic doses, ketamine is a promising agent for p ...
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PTSD
Post-traumatic stress disorder (PTSD) is a mental and behavioral disorder that can develop because of exposure to a traumatic event, such as sexual assault, warfare, traffic collisions, child abuse, domestic violence, or other threats on a person's life. Symptoms may include disturbing thoughts, feelings, or dreams related to the events, mental or physical distress to trauma-related cues, attempts to avoid trauma-related cues, alterations in the way a person thinks and feels, and an increase in the fight-or-flight response. These symptoms last for more than a month after the event. Young children are less likely to show distress but instead may express their memories through play. A person with PTSD is at a higher risk of suicide and intentional self-harm. Most people who experience traumatic events do not develop PTSD. People who experience interpersonal violence such as rape, other sexual assaults, being kidnapped, stalking, physical abuse by an intimate partner, an ...
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Chronic Depression
Dysthymia ( ), also known as persistent depressive disorder (PDD), is a mental disorder, mental and Abnormal behaviour, behavioral disease#Disorder, disorder, specifically a disorder primarily of mood disorder, mood, consisting of similar cognitive and physical problems as major depressive disorder, but with longer-lasting symptoms. The concept was used by Robert Spitzer (psychiatrist), Robert Spitzer as a replacement for the term "depressive personality" in the late 1970s. In the Diagnostic and Statistical Manual of Mental Disorders (DSM-IV), dysthymia is a serious state of chronic depression, which persists for at least two years (one year for children and adolescents). Dysthymia is not a minor form of major depressive disorder, and for some may be more disabling. As dysthymia is a chronic disorder, those with the condition may experience symptoms for many years before it is diagnosed, if diagnosis occurs at all. As a result, they may believe that depression is a part of their ...
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Suicidal Ideation
Suicidal ideation, or suicidal thoughts, means having thoughts, ideas, or ruminations about the possibility of ending one's own life.World Health Organization, ''ICD-11 for Mortality and Morbidity Statistics'', ver. 09/2020MB26.A Suicidal ideation/ref> It is not a diagnosis but is a symptom of some mental disorders and can also occur in response to adverse events without the presence of a mental disorder.Barry, Lisa C. Passive Suicidal Ideation in Older Adults: Implications for Suicide Prevention, ''American Journal of Geriatric Psychiatry'' 27, no. 12 (December 2019): 1411 ("... growing evidence points toward a subgroup of individuals who endorse passive SI uicidal ideationin later life outside the context of clinical depression.") On suicide risk scales, the range of suicidal ideation varies from fleeting thoughts to detailed planning. Passive suicidal ideation is thinking about not wanting to live or imagining being dead. Active suicidal ideation involves preparation to comm ...
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Intravenous Infusion
Intravenous therapy (abbreviated as IV therapy) is a medical technique that administers fluids, medications and nutrients directly into a person's vein. The intravenous route of administration is commonly used for rehydration or to provide nutrients for those who cannot, or will not—due to reduced mental states or otherwise—consume food or water by mouth. It may also be used to administer medications or other medical therapy such as blood products or electrolytes to correct electrolyte imbalances. Attempts at providing intravenous therapy have been recorded as early as the 1400s, but the practice did not become widespread until the 1900s after the development of techniques for safe, effective use. The intravenous route is the fastest way to deliver medications and fluid replacement throughout the body as they are introduced directly into the circulatory system and thus quickly distributed. For this reason, the intravenous route of administration is also used for the consum ...
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San Francisco (magazine)
''San Francisco'' is an American monthly magazine devoted to the people, culture, food, politics, and arts of the San Francisco Bay Area. It is published monthly by Modern Luxury publications. History There have been two separate ''San Francisco'' magazines published in San Francisco. One was started in the 1970s and published for many years, under a series of different publishers, until it went out of business around 1985. The magazine known as ''San Francisco'' has its roots starting in 1955, when San Francisco public broadcasting station KQED-TV began publishing a programming guide called ''KQED in Focus''. The program guide began to add more articles and took on the character of a regular magazine. The name was later changed to ''Focus Magazine'' and then to ''San Francisco Focus''. In 1984, a new programming guide, ''Fine Tuning'' was separated off from ''Focus'', with ''Focus'' carrying on as a self-contained magazine. ''San Francisco Focus'' was the recipient of a Na ...
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University Of Cincinnati
The University of Cincinnati (UC or Cincinnati) is a public research university in Cincinnati, Ohio. Founded in 1819 as Cincinnati College, it is the oldest institution of higher education in Cincinnati and has an annual enrollment of over 44,000 students, making it the second largest university in Ohio. It is part of the University System of Ohio. The university has four major campuses, with Cincinnati's main uptown campus and medical campus in the Heights and Corryville neighborhoods, and branch campuses in Batavia and Blue Ash, Ohio. The university has 14 constituent colleges, with programs in architecture, business, education, engineering, humanities, the sciences, law, music, and medicine. The medical college includes a leading teaching hospital and several biomedical research laboratories, with developments made including a live polio vaccine and diphenhydramine. UC was also the first university to implement a co-operative education (co-op) model. The university ...
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University Of Southern California
, mottoeng = "Let whoever earns the palm bear it" , religious_affiliation = Nonsectarian—historically Methodist , established = , accreditation = WSCUC , type = Private research university , academic_affiliations = , endowment = $8.12 billion (2021)As of June 30, 2021. , budget = $6.2 billion (2020–21) , president = Carol Folt , students = 49,318 (2021) , undergrad = 20,790 (2021) , postgrad = 28,528 (2021) , faculty = 4,706 (2021) , administrative_staff = 16,614 (2021) , city = , state = , country = United States , campus = Large City
University Park campus,

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Massachusetts General Hospital
Massachusetts General Hospital (Mass General or MGH) is the original and largest teaching hospital of Harvard Medical School located in the West End neighborhood of Boston, Massachusetts. It is the third oldest general hospital in the United States and has a capacity of 999 beds. With Brigham and Women's Hospital, it is one of the two founding members of Mass General Brigham (formerly known as Partners HealthCare), the largest healthcare provider in Massachusetts. Massachusetts General Hospital houses the largest hospital-based research program in the world, the Mass General Research Institute, with an annual research budget of more than $1 billion in 2019. It is currently ranked as the #8 best hospital in the United States by '' U.S. News & World Report''. In , ''The Boston Globe'' ranked MGH the fifth best place to work out of Massachusetts companies with over 1,000 employees. History Founded in 1811, the original hospital was designed by the famous American architect Charle ...
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UCLA
The University of California, Los Angeles (UCLA) is a public university, public Land-grant university, land-grant research university in Los Angeles, California. UCLA's academic roots were established in 1881 as a Normal school, teachers college then known as the southern branch of the California State Normal School (now San Jose State University, San José State University). This school was absorbed with the official founding of UCLA as the Southern Branch of the University of California in 1919, making it the second-oldest of the 10-campus University of California system (after UC Berkeley). UCLA offers 337 undergraduate and graduate degree programs in a wide range of disciplines, enrolling about 31,600 undergraduate and 14,300 graduate and professional students. UCLA received 174,914 undergraduate applications for Fall 2022, including transfers, making the school the most applied-to Higher education in the United States, university in the United States. The university is or ...
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American Anesthesiologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the " United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas The Americas, which are sometimes collectively called America, are a landmass comprising the totality of North and South America. The Americas make up most of the land in Earth's Western Hemisphere and comprise the New World. Along wit ..., also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headq ...
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