Spironucleus Salmonicida
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Spironucleus Salmonicida
''Spironucleus salmonicida'' is a species of fish parasite. It is a flagellate adapted to micro-aerobic environments that causes systemic infections in salmonid fish. The species creates foul-smelling, pus-filled abscesses in muscles and internal organs of aquarium fish. In the late 1980s when the disease was first reported, it was believed to be caused by ''Spironucleus barkhanus''. Anders Jørgensen was the person that found out what species really caused the disease. There is a distinct lack of models for diverse microbial eukaryotes. ''Spironucleus salmonicida'' was chosen as a model due to its complex genome and ability to adapt to fluctuating environments. This ability was proven by genetically modifying the pathogen and seeing the results. By comparing these results with the closest model organism, ''Giardia intestinalis'', researchers were able to see that the parasite has a more complex gene regulation system. This system of genetic modification was also used to sequence ...
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Anders Jørgensen
Anders is a male name in Scandinavian languages and Fering North Frisian, an equivalent of the Greek Andreas ("manly") and the English Andrew. It originated from Andres via metathesis. In Sweden, Anders has been one of the most common names for many centuries, earliest attested in 1378. It was common for priests and farmers during medieval times. According to Statistics Sweden, as of 31 December 2021 it ranks 4th among the male names. The great frequency of this name at the point in time (around 1900) when patronymics were converted into family names is the reason why 1 out of every 30 Swedes today is called Andersson. The name day of Anders in the Scandinavian calendar is 30 November, and in the old peasant superstition that day was important for determining what the Christmas weather would be. If it was very cold on 30 November there would be much sleet on Christmas (and vice versa). In Denmark Donald Duck's name is ''Anders And''. The Fering name Anders may have been bor ...
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Spironucleus Barkhanus
''Spironucleus'' is a diplomonad genus that is bilaterally symmetrical and can be found in various animal hosts. This genus is a binucleate flagellate, which is able to live in the anaerobic conditions of animal intestinal tracts. A characteristic of ''Spironucleus'' that is common to all metamonads is that it does not have aerobic mitochondria, but instead rely on hydrogenosomes to produce energy. ''Spironucleus'' has six anterior and two posterior flagella. The life cycle of ''Spironucleus'' involves one active trophozoite stage and one inactive cyst stage. ''Spironucleus'' undergoes asexual reproduction via longitudinal binary fission. Spironucleus vortens, ''Spironucleus'' ''vortens'' can cause lateral line erosion in freshwater anglefish. Spironucleus columbae, ''Spironucleus'' ''columbae'' is found to cause hexamitiasis in pigeons. Finally, Spironucleus muris, ''Spironucleus'' ''muris'' is found to cause illnesses of the digestive system in mice, rats, and hamsters. The genom ...
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Metamonads
The metamonads are a large group of flagellate amitochondriate microscopic eukaryotes. They include the retortamonads, diplomonads, parabasalids, oxymonads, and a range of more poorly studied taxa, most of which are free-living flagellates. All metamonads are Anaerobic organism, anaerobic (many being aerotolerant anaerobes), and most members of the four groups listed above are symbiosis, symbiotes or parasitism, parasites of animals, as is the case with Giardia duodenalis, ''Giardia lamblia'' which causes diarrhea in mammals. Characteristics A number of parabasalids and oxymonads are found in termite guts, and play an important role in breaking down the cellulose found in wood. Some other metamonads are Parasitism, parasites. These flagellates are unusual in lacking aerobic mitochondrion, mitochondria. Originally they were considered among the most primitive eukaryotes, diverging from the others before mitochondria appeared. However, they are now known to have lost aerobic mi ...
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Fish Diseases
Like humans and other animals, fish suffer from diseases and parasites. Fish defences against disease are specific and non-specific. Non-specific defences include skin and scales, as well as the mucus layer secreted by the epidermis that traps microorganisms and inhibits their growth. If pathogens breach these defences, fish can develop inflammatory responses that increase the flow of blood to infected areas and deliver white blood cells that attempt to destroy the pathogens. Specific defences are specialised responses to particular pathogens recognised by the fish's body, that is adaptative immune responses. In recent years, vaccines have become widely used in aquaculture and ornamental fish, for example vaccines for commercial food fishes like Aeromonas salmonicida, furunculosis in salmon and Lactococcosis\Streptococcosis in farmed grey mullet, Tilapia and koi herpes virus in koi. Some commercially important fish diseases are VHS, ICH, and whirling disease. Parasites ...
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Hydrogenosome
A hydrogenosome is a membrane-enclosed organelle found in some Anaerobic organism, anaerobic Ciliate, ciliates, Flagellate, flagellates, Fungus, fungi, and three species of Loricifera, loriciferans. Hydrogenosomes are highly variable organelles that have presumably evolved from protoMitochondrion, mitochondria to produce molecular hydrogen and Adenosine triphosphate, ATP in anaerobic conditions. Hydrogenosomes were discovered in 1973 by D. G. Lindmark and M. Müller. Because hydrogenosomes hold evolutionary lineage significance for organisms living in anaerobic or oxygen-stressed environments, many research institutions have since documented their findings on how the organelle differs in various sources. History Hydrogenosomes were isolated, purified, biochemically characterized and named in the early 1970s by Lindmark and Müller at Rockefeller University. In addition to this seminal study on hydrogenosomes, they also demonstrated for the first time the presence of Pyruvate:fe ...
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Giardia
''Giardia'' ( or ) is a genus of anaerobic flagellated protozoan parasites of the phylum Metamonada that colonise and reproduce in the small intestines of several vertebrates, causing the disease giardiasis. Their life cycle alternates between a binucleated motile trophozoite and an infective, metabolically inert, environmentally resistant tetranucleate cyst. Cysts are transmitted between hosts through the fecal-oral route, contaminated water and/or food. ''Giardia'' were first seen by the Dutch microscopist Antonie van Leeuwenhoek in 1681 under the light microscope. The genus is named after French zoologist Alfred Mathieu Giard. Characteristics ''Giardia'' trophozoites are 12–15 μm long and 5–9 μm wide and have a shape of a pear bisected lengthwise. Like other diplomonads, ''Giardia'' has two transcriptionally operational nuclei that contain an equal number of well-defined chromosomes and replicate synchronously with the cell division. The cytoskeleton of ...
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Giardia Intestinalis
''Giardia duodenalis'', also known as ''Giardia intestinalis'' and ''Giardia lamblia'', is a flagellated parasitic protozoan microorganism of the genus ''Giardia'' that colonizes the small intestine, causing a diarrheal condition known as giardiasis. The parasite attaches to the intestinal epithelium by a ventral disc (''syn''. adhesive disc or sucker), and reproduces via binary fission. ''G. duodenalis'' is a non-invasive parasite, that does not spread to other parts of the gastrointestinal tract, but remains confined to the lumen of the small intestine. The parasite exists in two forms; trophozoites and cysts. The microorganism can undergo encystation, transforming into a dormant cyst that enables it to survive outside of its host. ''Giardia'' trophozoites are anaerobic, and absorb their nutrients from the intestinal lumen. If the organism is stained, its characteristic pattern resembles the familiar " smiley face" symbol. Chief pathways of human infection include ingestio ...
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Model Organism
A model organism is a non-human species that is extensively studied to understand particular biological phenomena, with the expectation that discoveries made in the model organism will provide insight into the workings of other organisms. Model organisms are widely used to research human disease when human experimentation would be unfeasible or unethical. This strategy is made possible by the common descent of all living organisms, and the conservation of metabolic and developmental pathways and genetic material over the course of evolution. Research using animal models has been central to most of the achievements of modern medicine. It has contributed most of the basic knowledge in fields such as human physiology and biochemistry, and has played significant roles in fields such as neuroscience and infectious disease. The results have included the near- eradication of polio and the development of organ transplantation, and have benefited both humans and animals. From 19 ...
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Salmonids
Salmonidae (, ) is a family of ray-finned fish, the only extant member of the suborder Salmonoidei, consisting of 11 extant genera and over 200 species collectively known as "salmonids" or "salmonoids". The family includes salmon (both Atlantic and Pacific species), trout (both ocean-going and landlocked), char, graylings, freshwater whitefishes, taimens and lenoks, all coldwater mid-level predatory fish that inhabit the subarctic and cool temperate waters of the Northern Hemisphere. The Atlantic salmon (''Salmo salar''), whose Latin name became that of its genus ''Salmo'', is also the eponym of the family and order names. Salmonids have a relatively primitive appearance among teleost fish, with the pelvic fins being placed far back, and an adipose fin towards the rear of the back. They have slender bodies with rounded scales and forked tail fins, and their mouths contain a single row of sharp teeth. Although the smallest salmonid species is just long for adults, most salm ...
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Species
A species () is often defined as the largest group of organisms in which any two individuals of the appropriate sexes or mating types can produce fertile offspring, typically by sexual reproduction. It is the basic unit of Taxonomy (biology), classification and a taxonomic rank of an organism, as well as a unit of biodiversity. Other ways of defining species include their karyotype, DNA sequence, morphology (biology), morphology, behaviour, or ecological niche. In addition, palaeontologists use the concept of the chronospecies since fossil reproduction cannot be examined. The most recent rigorous estimate for the total number of species of eukaryotes is between 8 and 8.7 million. About 14% of these had been described by 2011. All species (except viruses) are given a binomial nomenclature, two-part name, a "binomen". The first part of a binomen is the name of a genus to which the species belongs. The second part is called the specific name (zoology), specific name or the specific ...
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Internal Organs
In a multicellular organism, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerves that innervate the parenchyma, the blood vessels that oxygenate and nourish it and carry away its metabolic wa ...
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Muscles
Muscle is a soft tissue, one of the four basic types of animal tissue. There are three types of muscle tissue in vertebrates: skeletal muscle, cardiac muscle, and smooth muscle. Muscle tissue gives skeletal muscles the ability to muscle contraction, contract. Muscle tissue contains special Muscle contraction, contractile proteins called actin and myosin which interact to cause movement. Among many other muscle proteins, present are two regulatory proteins, troponin and tropomyosin. Muscle is formed during embryonic development, in a process known as myogenesis. Skeletal muscle tissue is striated consisting of elongated, multinucleate muscle cells called muscle fibers, and is responsible for movements of the body. Other tissues in skeletal muscle include tendons and perimysium. Smooth and cardiac muscle contract involuntarily, without conscious intervention. These muscle types may be activated both through the interaction of the central nervous system as well as by innervation ...
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