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Sophoradin
Sophoradin is an isoprenyl chalconoid, a type of polyphenolic compound, found in '' Sophora tonkinensis'', an herb used in traditional Chinese medicine Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical practice drawn from traditional medicine in China. A large share of its claims are pseudoscientific, with the majority of treatments having no robust evidence .... Sofalcone is an oral gastrointestinal medication and a synthetic analog of sophoradin. References Chalconoids {{phenol-stub ...
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Sophora Tonkinensis
''Sophora tonkinensis'' is a herb used in traditional Chinese medicine. Sofalcone is an oral gastrointestinal medication and a synthetic derivative of sophoradin Sophoradin is an isoprenyl chalconoid, a type of polyphenolic compound, found in '' Sophora tonkinensis'', an herb used in traditional Chinese medicine Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical prac ..., an isoprenyl chalcone found in ''S. tonkinensis''. References External links tonkinensis Taxa named by François Gagnepain {{Sophoreae-stub ...
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Sofalcone
Sofalcone ( INN) is an oral gastrointestinal medication used in Japan. It is a synthetic analog of sophoradin, a type of natural phenol found in ''Sophora tonkinensis'', an herb used in traditional Chinese medicine Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical practice drawn from traditional medicine in China. A large share of its claims are pseudoscientific, with the majority of treatments having no robust evidence .... References Drugs acting on the gastrointestinal system and metabolism Phenol ethers Chalconoids {{gastrointestinal-drug-stub ...
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Chalconoid
Chalconoids ( Greek: χαλκός ''khalkós'', "copper", due to its color), also known as chalcones, are natural phenols In organic chemistry, phenols, sometimes called phenolics, are a class of chemical compounds consisting of one or more hydroxyl groups (− O H) bonded directly to an aromatic hydrocarbon group. The simplest is phenol, . Phenolic compounds ar ... derived from chalcone. They form the central core for a variety of important biological compounds. They show antibacterial, antifungal, antitumor and anti-inflammatory properties. Some chalconoids demonstrated the ability to block voltage-dependent potassium channels. Chalcones are also natural aromatase inhibitors. Chalcones are aromatic ketones with two phenyl rings that are also intermediates in the synthesis of many biological compounds. The closure of hydroxy chalcones causes the formation of the flavonoid structure. Flavonoids are substances in the plant's secondary metabolism with an array of bio ...
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Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical practice drawn from traditional medicine in China. A large share of its claims are pseudoscientific, with the majority of treatments having no robust evidence of effectiveness or logical mechanism of action. Some TCM ingredients Traditional Chinese medicine#Safety, are known to be toxic and cause disease, including cancer. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, Scholar-official, literati theory and Confucianism, Confucian philosophy, Chinese herbology, herbal remedies, Chinese food therapy, food, diet, exercise, medical specializations, and schools of thought. TCM as it exists today has been described as a largely 20th century invention. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selec ...
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Analog (chemistry)
A structural analog, also known as a chemical analog or simply an analog, is a compound having a structure similar to that of another compound, but differing from it in respect to a certain component. It can differ in one or more atoms, functional groups, or substructures, which are replaced with other atoms, groups, or substructures. A structural analog can be imagined to be formed, at least theoretically, from the other compound. Structural analogs are often isoelectronic. Despite a high chemical similarity, structural analogs are not necessarily functional analogs and can have very different physical, chemical, biochemical, or pharmacological properties. In drug discovery, either a large series of structural analogs of an initial lead compound are created and tested as part of a structure–activity relationship study or a database is screened for structural analogs of a lead compound. Chemical analogues of illegal drugs are developed and sold in order to circumvent la ...
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