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Sodium Hypochlorite Washes
Sodium hypochlorite washes are skin cleansers formulated with sodium hypochlorite (NaOCl) and surfactants. These cleansing liquids or gels are lathered onto wet skin and rinsed off. They are recommended for inflammatory skin conditions (eczema, atopic dermatitis and radiation dermatitis), microbial driven skin disorders (folliculitis, acne, ring worm, skin infections and staph colonization) and body odor. Sodium hypochlorite bath Sodium hypochlorite baths became an acceptable treatment of atopic dermatitis due to a 2009 landmark study by JT Huan. The use of sodium hypochlorite in the form of a bleach bath, has been reported to improve atopic dermatitis severity in children with moderate-to-severe dermatitis or eczema. Solutions of 0.05–0.06% NaOCl are considered safe and still maintain bactericidal activity against Staphylococcus aureus. Bleach bath dilution can be achieved by adding approximately 1/4 cup of household bleach (6% or 8.5%) to a ½ bathtub (13 gallons) of water. A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Hypochlorite
Sodium hypochlorite is an alkaline inorganic chemical compound with the formula (also written as NaClO). It is commonly known in a dilute aqueous solution as bleach or chlorine bleach. It is the sodium salt of hypochlorous acid, consisting of sodium cations () and hypochlorite anions (, also written as and ). The anhydrous compound is unstable and may decompose explosively. It can be crystallized as a pentahydrate , a pale greenish-yellow solid which is not explosive and is stable if kept refrigerated. Sodium hypochlorite is most often encountered as a pale greenish-yellow dilute solution referred to as chlorine bleach, which is a household chemical widely used (since the 18th century) as a disinfectant and bleaching agent. In solution, the compound is unstable and easily decomposes, liberating chlorine, which is the active principle of such products. Sodium hypochlorite is still the most important chlorine-based bleach. Its corrosive properties, common availability, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dermatitis
Dermatitis is a term used for different types of skin inflammation, typically characterized by itchiness, redness and a rash. In cases of short duration, there may be small blisters, while in long-term cases the skin may become thickened. The area of skin involved can vary from small to covering the entire body. Dermatitis is also called eczema but the same term is often used for the most common type of skin inflammation, atopic dermatitis. The exact cause of the condition is often unclear. Cases may involve a combination of allergy and poor venous return. The type of dermatitis is generally determined by the person's history and the location of the rash. For example, irritant dermatitis often occurs on the hands of those who frequently get them wet. Allergic contact dermatitis occurs upon exposure to an allergen, causing a hypersensitivity reaction in the skin. Prevention of atopic dermatitis is typically with essential fatty acids, and may be treated with moistu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atopic Dermatitis
Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. Atopic dermatitis is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. Atopic dermatitis results in puritis, itchy, red, swollen, and cracked skin. Clear fluid may come from the affected areas, which can thicken over time. Atopic dermatitis affects about 20% of people at some point in their lives. It is more common in younger children. Females are affected slightly more often than males. Many people outgrow the condition. While the condition may occur at any age, it typically starts in childhood, with changing severity over the years. In children under one year of age, the face and limbs and much of the body may be affected. As children get older, the areas on the insides of the knees and folds of the elbows and around the neck are most commonly affected. In adults, the hands and feet are commonly affec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NF-κB
Nuclear factor kappa-light-chain-enhancer of activated B cells (NF-κB) is a family of transcription factor protein complexes that controls transcription (genetics), transcription of DNA, cytokine production and cell survival. NF-κB is found in almost all animal cell types and is involved in cellular responses to stimuli such as stress, cytokines, free radicals, heavy metals, ultraviolet irradiation, oxidized LDL, and bacterial or viral antigens. NF-κB plays a key role in regulating the immune response to infection. Incorrect regulation of NF-κB has been linked to cancer, inflammatory and autoimmune diseases, septic shock, viral infection, and improper immune development. NF-κB has also been implicated in processes of synaptic plasticity and memory. Discovery NF-κB was discovered by Ranjan Sen in the lab of Nobel laureate David Baltimore via its interaction with an 11-base pair sequence in the immunoglobulin light-chain Enhancer (genetics), enhancer in B cells. Later work ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Academy Of Dermatology
The American Academy of Dermatology (AAD) is a non-profit professional organization of dermatologists in the United States and Canada, based in Rosemont, Illinois, near Chicago. It was founded in 1938 and has more than ''21,000'' members. The Academy grants fellowships and associate memberships, as well as fellowships for nonresidents of the United States or Canada. Since 1979, the AAD also publishes a monthly medical journal, the ''Journal of the American Academy of Dermatology''. To become a Fellow of the American Academy of Dermatology (FAAD), a physician must be a resident of the United States of America or Canada and certified by the American Board of Dermatology or in dermatology by the Royal College of Physicians and Surgeons of Canada. To become an associate member, a physician must have three years of experience in practice or as a teacher or graduate student of dermatology and must have had training that qualifies for examination by the American Board of Dermatology or t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Body Surface Area
In physiology and medicine, the body surface area (BSA) is the measured or calculated surface area of a human body. For many clinical purposes, BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass. Nevertheless, there have been several important critiques of the use of BSA in determining the dosage of medications with a narrow therapeutic index, such as chemotherapy. Typically there is a 4–10 fold variation in drug clearance between individuals due to differing the activity of drug elimination processes related to genetic and environmental factors. This can lead to significant overdosing and underdosing (and increased risk of disease recurrence). It is also thought to be a distorting factor in Phase I and II trials that may result in potentially helpful medications being prematurely rejected. The trend to personalized medicine is one approach to counter this weakness. Uses Examples of uses of the BSA: * Renal clea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Compounds
Sodium atoms have 11 electrons, one more than the stable configuration of the noble gas neon. As a result, sodium usually forms ionic compounds involving the Na+ cation. Sodium is a reactive alkali metal and is much more stable in ionic compounds. It can also form intermetallic compounds and organosodium compounds. Sodium compounds are often soluble in water. Metallic sodium Metallic sodium is generally less reactive than potassium and more reactive than lithium. Sodium metal is highly reducing, with the standard reduction potential for the Na+/Na couple being −2.71 volts, though potassium and lithium have even more negative potentials. The thermal, fluidic, chemical, and nuclear properties of molten sodium metal have caused it to be one of the main coolants of choice for the fast breeder reactor. Such nuclear reactors are seen as a crucial step for the production of clean energy. Salts and oxides Sodium compounds are of immense commercial importance, being particularly centr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
