Smegma Penis02
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Smegma Penis02
Smegma (from Ancient Greek ) is shed skin cells, skin oils, and moisture that occurs in male and female mammalian genitalia. In males, smegma collects under the foreskin; in females, it collects around the clitoris and in the folds of the labia minora. Females The accumulation of sebum combined with dead skin cells forms smegma. ''Smegma clitoridis'' is defined as the secretion of the apocrine (sweat) and sebaceous (sebum) glands of the clitoris in combination with desquamating epithelial cells. Glands that are located around the clitoris, the labia minora, and the labia majora secrete sebum. If smegma is not removed frequently it can lead to clitoral adhesion which can make clitoral stimulation (such as masturbation) painful (clitorodynia). Males In males, smegma helps keep the glans moist and facilitates sexual intercourse by acting as a lubricant. Smegma was originally thought to be produced by sebaceous glands near the frenulum called Tyson's glands; however, su ...
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Ancient Greek
Ancient Greek (, ; ) includes the forms of the Greek language used in ancient Greece and the classical antiquity, ancient world from around 1500 BC to 300 BC. It is often roughly divided into the following periods: Mycenaean Greek (), Greek Dark Ages, Dark Ages (), the Archaic Greece, Archaic or Homeric Greek, Homeric period (), and the Classical Greece, Classical period (). Ancient Greek was the language of Homer and of fifth-century Athens, fifth-century Athenian historians, playwrights, and Ancient Greek philosophy, philosophers. It has contributed many words to English vocabulary and has been a standard subject of study in educational institutions of the Western world since the Renaissance. This article primarily contains information about the Homeric Greek, Epic and Classical periods of the language, which are the best-attested periods and considered most typical of Ancient Greek. From the Hellenistic period (), Ancient Greek was followed by Koine Greek, which is regar ...
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Squalene
Squalene is an organic compound. It is a triterpene with the formula C30H50. It is a colourless oil, although impure samples appear yellow. It was originally obtained from shark liver oil (hence its name, as '' Squalus'' is a genus of sharks). An estimated 12% of bodily squalene in humans is found in sebum. Squalene has a role in topical skin lubrication and protection. Most plants, fungi, and animals produce squalene as biochemical precursor in sterol biosynthesis, including cholesterol and steroid hormones in the human body. It is also an intermediate in the biosynthesis of hopanoids in many bacteria. Squalene is an important ingredient in some vaccine adjuvants: The Novartis and GlaxoSmithKline adjuvants are called MF59 and AS03, respectively. Role in triterpenoid synthesis Squalene is a biochemical precursor to both steroids and hopanoids. For sterols, the squalene conversion begins with oxidation (via squalene monooxygenase) of one of its terminal double bonds, ...
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Taylorella Equigenitalis
Taylorella is a genus comprising Gram-negative, short rod-shaped, chemoorganotrophic bacteria that include species that are the causative agents of contagious equine metritis. The name Taylorella serves as a dedication to C.E.D. Taylor, the scientist who identified the only species originally included in this genus. They are non-motile microaerophiles that are able to be isolated in pure culture on chocolate agar. . Phylogeny The genus Taylorella was first identified by C.E.D Taylor in 1978. It was formerly classified under the genus Haemophilus, and there was originally considerable debate on whether it is more closely related to Moraxella. Due to further investigation by DNA: DNA hybridization and genomic characteristics of this genus, Sugimoto et al. 1983 proposed the creation of a new genus that would include two species isolated from the family Equidae. The species include: * '' Taylorella equigenitalis'': causes contagious equine metritis in horses. * '' Taylorella asinig ...
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Urethral Diverticulum
A urethral diverticulum is a condition where the urethra or the periurethral glands push into the connective tissue layers (fascia) that surround it. Signs and symptoms Urethral diverticula are often asymptomatic and symptoms that are present tend to be nonspecific. They can co-occur with cancer, in approximately 6-9% of cases, most commonly adenocarcinoma, but also including squamous cell carcinoma and transitional cell carcinoma. Approximately 10% of cases co-occur with kidney stones. There are 2 types of urethral diverticulums. Congenital and acquired. In infancy usually the urethral diverticulum is congenital but in rare instances acquired urethral diverticulum can be seen in infancy specially following traumatic catheterization. Common symptoms of urethral diverticulum include Urinary incontinence, incontinence, urinary frequency and urgency, dyspareunia, pain during sex, and dysuria, pain during urination. Other symptoms include pain localized to the urethra or pelvis and ...
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Urethral Fossa
A stallion is an adult male horse that has not been gelded ( castrated). Stallions follow the conformation and phenotype of their breed, but within that standard, the presence of hormones such as testosterone may give stallions a thicker, "cresty" neck, as well as a somewhat more muscular physique as compared to female horses, known as ''mares'', and castrated males, called ''geldings''. Temperament varies widely based on genetics and training, but because of their instincts as herd animals, they may be prone to aggressive behavior, particularly toward other stallions, and thus require careful management by knowledgeable handlers. With proper training and management, stallions are effective equine athletes at the highest levels of many disciplines, including horse racing, horse shows, and international Olympic competition. "Stallion" is also used to refer to males of other equids, including zebras and donkeys. Herd behavior Young female horses usually leave their band an ...
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Equine
Equinae is a subfamily of the family Equidae, known from the Hemingfordian stage of the Early Miocene (16 million years ago) onwards. They originated in North America, before dispersing to every continent except Australia and Antarctica. They are thought to be a monophyletic grouping. Members of the subfamily are referred to as equines; the only extant equines are the horses, asses, and zebras of the genus ''Equus'', with two other genera '' Haringtonhippus'' and '' Hippidion'' becoming extinct at the beginning of the Holocene, around 11–12,000 years ago. The subfamily contains two tribes, the Equini and the Hipparionini, as well as two unplaced genera, ''Merychippus'' and ''Scaphohippus''. Members of the family ancestrally had three toes, while members of the tribe Equini from the Middle Miocene onwards developed monodactyl feet. Sister taxa * Anchitheriinae * Hyracotheriinae ''Hyracotherium'' ( ; " hyrax-like beast") is an extinct genus of small (about 60 cm in leng ...
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Tritrichomonas Foetus
''Tritrichomonas foetus'' is a species of single-celled flagellated parasites that is known to be a pathogen of the bovine reproductive tract as well as the intestinal tract of cats. In cattle, the organism is transmitted to the female vagina and uterus from the foreskin of the bull where the parasite is known to reside. It causes infertility, and, at times, has caused spontaneous abortions in the first trimester. In the last ten years, there have been reports of ''Tritrichomonas foetus'' in the feces of young cats that have diarrhea and live in households with multiple cats. ''Tritrichomonas foetus'' looks similarly to ''Giardia'' and is often misdiagnosed for it when viewed under a microscope. Cause ''Tritrichomonas foetus'' is the genus '' Tritrichomonas'' within the order Tritrichomonadida in the clade Parabasalia. The parasite is 5-25 μm in size and is spindle shaped with four flagella, which are whiplike projections, and an undulating or wavy membrane. Three o ...
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American Cancer Society
The American Cancer Society (ACS) is a nationwide non-profit organization dedicated to eliminating cancer. The ACS publishes the journals ''Cancer'', '' CA: A Cancer Journal for Clinicians'' and '' Cancer Cytopathology''. History The society was founded on May 22, 1913, by ten physicians and five businessmen in New York City under the name "American Society for the Control of Cancer" (ASCC). The current name was adopted in 1944. At the time of founding, it was not considered appropriate to mention the word "cancer" in public and information concerning this illness was cloaked in a climate of fear and denial. The top item on the founders' agenda was to raise awareness of cancer, before any other progress could be made in funding research. Therefore, a frenetic writing campaign was undertaken to educate doctors, nurses, patients and family members about cancer. Articles were written for popular magazines and professional journals. The ASCC undertook to publish their own journal, ...
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Penile Cancer
Penile cancer, or penile carcinoma, is a cancer that develops in the skin or tissues of the penis. Symptoms may include abnormal growth, an ulcer or sore on the skin of the penis, and bleeding or foul smelling discharge. Risk factors include phimosis (inability to retract the foreskin of the penis), chronic inflammation, smoking, HPV infection, condylomata acuminate, having multiple sexual partners, and early age of sexual intercourse. Around 95% of penile cancers are squamous-cell carcinomas. Other types of penile cancer such as Merkel-cell carcinoma, small-cell carcinoma, and melanoma are generally rare. In 2020, it occurred in 36,000 men and caused 13,000 deaths. Signs and symptoms Penile cancer can present as redness and irritation on the penis with a skin thickening on the glans or inner foreskin or an ulcerative, outward growingexophytic or “finger-like” (papillary) growth. Penile cancer may accompany penile discharge with or without difficulty or burning or tingli ...
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Phimosis
Phimosis (from Greek language, Greek φίμωσις ''phimōsis'' 'muzzling') is a condition in which the foreskin of the Human penis, penis cannot stretch to allow it to be pulled back past the Glans penis, glans. A balloon-like swelling under the foreskin may occur with urination. In teenagers and adults, it may result in pain during an erection, but is otherwise not painful. Those affected are at greater risk of inflammation of the glans, known as balanitis, and other complications. In infancy, phimosis is considered physiological (normal). At birth, the foreskin is naturally adhered to the glans, and cannot be retracted. As the child ages, in most cases, the foreskin will naturally detach. In young boys, it is normal not to be able to pull back the foreskin at all. Over 90% of cases resolve by the age of seven, although full retraction is still prevented by balanopreputial adhesions in over half at this age. Occasionally, phimosis may be caused by an underlying condition s ...
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Cytokines
Cytokines () are a broad and loose category of small proteins (~5–25 kDa) important in cell signaling. Cytokines are produced by a broad range of cells, including immune cells like macrophages, B cell, B lymphocytes, T cell, T lymphocytes and mast cells, as well as Endothelium, endothelial cells, fibroblasts, and various stromal cells; a given cytokine may be produced by more than one type of cell. Due to their size, cytokines cannot cross the lipid bilayer of cells to enter the cytoplasm and therefore typically exert their functions by interacting with specific cytokine receptor, cytokine receptors on the target cell surface. Cytokines are especially important in the immune system; cytokines modulate the balance between humoral immunity, humoral and cell-mediated immunity, cell-based immune responses, and they regulate the maturation, growth, and responsiveness of particular cell populations. Some cytokines enhance or inhibit the action of other cytokines in complex way ...
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Lysozymes
Lysozyme (, muramidase, ''N''-acetylmuramide glycanhydrolase; systematic name peptidoglycan ''N''-acetylmuramoylhydrolase) is an antimicrobial enzyme produced by animals that forms part of the innate immune system. It is a glycoside hydrolase that catalyzes the following process: : Hydrolysis of (1→4)-β-linkages between ''N''-acetylmuramic acid and ''N''-acetyl-D-glucosamine residues in a peptidoglycan and between ''N''-acetyl-D-glucosamine residues in chitodextrins Peptidoglycan is the major component of gram-positive bacterial cell wall. This hydrolysis in turn compromises the integrity of bacterial cell walls causing lysis of the bacteria. Lysozyme is abundant in secretions including tears, saliva, human milk, and mucus. It is also present in cytoplasmic granules of the macrophages and the polymorphonuclear neutrophils (PMNs). Large amounts of lysozyme can be found in egg white. C-type lysozymes are closely related to α-lactalbumin in sequence and structure, making t ...
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