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Slip Bond
A slip bond is a type of chemical noncovalent bond In chemistry, a non-covalent interaction differs from a covalent bond in that it does not involve the sharing of electrons, but rather involves more dispersed variations of electromagnetic interactions between molecules or within a molecule. The ... whose dissociation lifetime decreases with tensile force applied to the bond. This is the expected behaviour for chemical bonds, but exceptions, like catch bonds exist. References Chemical bonding Biophysics Cell adhesion {{biochem-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Noncovalent Bond
In chemistry, a non-covalent interaction differs from a covalent bond in that it does not involve the sharing of electrons, but rather involves more dispersed variations of electromagnetic interactions between molecules or within a molecule. The chemical energy released in the formation of non-covalent interactions is typically on the order of 1–5 kcal/ mol (1000–5000 calories per 6.02 molecules). Non-covalent interactions can be classified into different categories, such as electrostatic, π-effects, van der Waals forces, and hydrophobic effects. Non-covalent interactions are critical in maintaining the three-dimensional structure of large molecules, such as proteins and nucleic acids. They are also involved in many biological processes in which large molecules bind specifically but transiently to one another (see the properties section of the DNA page). These interactions also heavily influence drug design, crystallinity and design of materials, particularly for self-assemb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dissociation (chemistry)
Dissociation in chemistry is a general process in which molecules (or ionic compounds such as salt (chemistry), salts, or coordination complex, complexes) separate or split into other things such as atoms, ions, or radical (chemistry), radicals, usually in a reversible manner. For instance, when an acid dissolves in water, a covalent bond between an electronegativity, electronegative atom and a hydrogen atom is broken by heterolytic fission, which gives a proton (H+) and a negative ion. Dissociation is the opposite of association or recombination. Dissociation constant For reversible dissociations in a chemical equilibrium :AB A + B the dissociation constant ''K''d is the ratio of dissociated to undissociated compound :K_d = \mathrm where the brackets denote the equilibrium concentrations of the species. Dissociation degree The dissociation degree \alpha is the fraction of original solute molecules that have dissociated. It is usually indicated by the Greek symbol α. More acc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tension (physics)
Tension is the pulling or stretching force transmitted axially along an object such as a string, rope, chain, rod, truss member, or other object, so as to stretch or pull apart the object. In terms of force, it is the opposite of ''compression''. Tension might also be described as the action-reaction pair of forces acting at each end of an object. At the atomic level, when atoms or molecules are pulled apart from each other and gain potential energy with a restoring force still existing, the restoring force might create what is also called tension. Each end of a string or rod under such tension could pull on the object it is attached to, in order to restore the string/rod to its relaxed length. Tension (as a transmitted force, as an action-reaction pair of forces, or as a restoring force) is measured in newtons in the International System of Units (or pounds-force in Imperial units). The ends of a string or other object transmitting tension will exert forces on the objects ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Catch Bond
A catch bond is a type of noncovalent bond whose dissociation (chemistry), dissociation lifetime increases with tensile force applied to the bond. Normally, bond lifetimes are expected to diminish with force. In the case of catch bonds, the lifetime of the bond actually increases up to a maximum before it decreases like in a normal bond. Catch bonds work in a way that is conceptually similar to that of a Chinese finger trap. While catch bonds are strengthened by an increase in force, the force increase is not necessary for the bond to work. Catch bonds were suspected for many years to play a role in the rolling of leukocytes, being strong enough to roll in presence of high forces caused by high shear stresses, while avoiding getting stuck in capillaries where the fluid flow, and therefore shear stress, is low. The existence of catch bonds was debated for many years until strong evidence of their existence was found in bacteria. Definite proof of their existence came shortly thereafte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
