Sir Frank Macfarlane Burnet
Sir Frank Macfarlane Burnet (3 September 1899 – 31 August 1985), usually known as Macfarlane or Mac Burnet, was an Australian virologist known for his contributions to immunology. He won a Nobel Prize in 1960 for predicting acquired immune tolerance. He also developed the theory of clonal selection. Burnet received his Doctor of Medicine degree from the University of Melbourne in 1924, and his PhD from the University of London in 1928. He went on to conduct pioneering research in microbiology and immunology at the Walter and Eliza Hall Institute of Medical Research, Melbourne, and served as director of the Institute from 1944 to 1965. From 1965 until his retirement in 1978, Burnet worked at the University of Melbourne. Throughout his career he played an active role in the development of public policy for the medical sciences in Australia and was a founding member of the Australian Academy of Science (AAS), and served as its president from 1965 to 1969. Burnet's major achievem ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Traralgon
Traralgon ( , ) is a city located in the east of the Latrobe Valley in the Gippsland region of Victoria (Australia), Victoria, Australia and the most populous city in the City of Latrobe and the region. The urban population of Traralgon at the was 26,907. It is the largest and fastest growing city in the greater Latrobe Valley area, which has a population of 77,168 at the 2021 Census and is administered by the City of Latrobe. Naming The origin of the name Traralgon is unconfirmed. The name was used for the pastoral lease of the Hobson brothers in 1844, centred on Traralgon Creek, and was alternatively rendered 'Tralgon' by Dr Edumund Hobson. The town was also spelt "Taralgon" in the earliest records of the Gippsland Times available in 1861. The Gippsland Farmers' Journal wrote in 1889 that the town name was originally spelt 'Tarralgon' and that it was the Indigenous name for 'the river of little fish'. However, these words are not reflected in modern linguists' knowledge of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Immune Tolerance
Immune tolerance, also known as immunological tolerance or immunotolerance, refers to the immune system's state of unresponsiveness to substances or tissues that would otherwise trigger an immune response. It arises from prior exposure to a specific antigen and contrasts the immune system's conventional role in eliminating foreign antigens. Depending on the site of induction, tolerance is categorized as either central tolerance, occurring in the thymus and bone marrow, or peripheral tolerance, taking place in other tissues and lymph nodes. Although the mechanisms establishing central and peripheral tolerance differ, their outcomes are analogous, ensuring immune system modulation. Immune tolerance is important for normal physiology and homeostasis. Central tolerance is crucial for enabling the immune system to differentiate between self and non-self antigens, thereby preventing autoimmunity. Peripheral tolerance plays a significant role in preventing excessive immune reactions to en ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hen's Eggs
Humans and other hominids have consumed eggs for millions of years. The most widely consumed eggs are those of fowl, especially chickens. People in Southeast Asia began harvesting chicken eggs for food by 1500 BCE. Eggs of other birds, such as ducks and ostriches, are eaten regularly but much less commonly than those of chickens. People may also eat the eggs of reptiles, amphibians, and fish. Fish eggs consumed as food are known as roe or caviar. Hens and other egg-laying creatures are raised throughout the world, and mass production of chicken eggs is a global industry. In 2009, an estimated 62.1 million metric tons of eggs were produced worldwide from a total laying flock of approximately 6.4 billion hens. There are issues of regional variation in demand and expectation, as well as current debates concerning methods of mass production. In 2012, the European Union banned battery husbandry of chickens. History Bird eggs have been valuable foodstuffs since prehistory, in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Influenza Vaccine
Influenza vaccines, colloquially known as flu shots or the flu jab, are vaccines that protect against infection by influenza viruses. New versions of the vaccines are developed twice a year, as the influenza virus rapidly changes. While their effectiveness varies from year to year, most provide modest to high protection against influenza. Vaccination against influenza began in the 1930s, with large-scale availability in the United States beginning in 1945. Both the World Health Organization and the US Centers for Disease Control and Prevention (CDC) recommend yearly vaccination for nearly all people over the age of six months, especially those at high risk, and the influenza vaccine is on the WHO Model List of Essential Medicines, World Health Organization's List of Essential Medicines. The European Centre for Disease Prevention and Control (ECDC) also recommends yearly vaccination of high-risk groups, particularly pregnant women, the elderly, children between six months and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Myxomatosis
Myxomatosis is a disease caused by '' Myxoma virus'', a poxvirus in the genus '' Leporipoxvirus''. The natural hosts are tapeti (''Sylvilagus brasiliensis'') in South and Central America, and brush rabbits (''Sylvilagus bachmani'') in North America. The myxoma virus causes only a mild disease in these species, but causes a severe and usually fatal disease in European rabbits (''Oryctolagus cuniculus''), the species of rabbit commonly raised for companionship and as a food source. Myxomatosis is an example of what occurs when a virus jumps from a species adapted to the virus to a naive host, and has been extensively studied for this reason. The virus was intentionally introduced in Australia, France, and Chile in the 1950s to control wild European rabbit populations. Cause ''Myxoma virus'' is in the genus '' Leporipoxvirus'' (family ''Poxviridae''; subfamily ''Chordopoxvirinae''). Like other poxviruses, myxoma viruses are large DNA viruses with linear double-stranded DNA. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Viral Strain
In biology, a strain is a genetic variant, a subtype or a culture within a biological species. Strains are often seen as inherently artificial concepts, characterized by a specific intent for genetic isolation. This is most easily observed in microbiology where strains are derived from a single cell colony and are typically quarantined by the physical constraints of a Petri dish. Strains are also commonly referred to within virology, botany, and with rodents used in experimental studies. Microbiology and virology It has been said that "there is no universally accepted definition for the terms 'strain', ' variant', and 'isolate' in the virology community, and most virologists simply copy the usage of terms from others". A strain is a genetic variant or subtype of a microorganism such as a bacterial strain or a specific strain of a virus, or fungus. For example, a "flu strain" is a certain biological form of the influenza or "flu" virus. These flu strains are characterized by ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Influenza Virus
''Orthomyxoviridae'' () is a family of negative-sense RNA viruses. It includes nine genera: '' Alphainfluenzavirus'', '' Betainfluenzavirus'', '' Gammainfluenzavirus'', '' Deltainfluenzavirus'', '' Isavirus'', '' Mykissvirus'', '' Quaranjavirus'', '' Sardinovirus'', and '' Thogotovirus''. The first four genera contain viruses that cause influenza in birds (see also avian influenza) and mammals, including humans. Isaviruses infect salmon; the thogotoviruses are arboviruses, infecting vertebrates and invertebrates (such as ticks and mosquitoes). The Quaranjaviruses are also arboviruses, infecting vertebrates (birds) and invertebrates (arthropods). The four genera of Influenza virus that infect vertebrates, which are identified by antigenic differences in their nucleoprotein and matrix protein, are as follows: * '' Alphainfluenzavirus'' infects humans, other mammals, and birds, and causes all flu pandemics * '' Betainfluenzavirus'' infects humans and seals * '' Gammainfluenz ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Assay
An assay is an investigative (analytic) procedure in laboratory medicine, mining, pharmacology, environmental biology and molecular biology for qualitatively assessing or quantitatively measuring the presence, amount, or functional activity of a target entity. The measured entity is often called the analyte, the measurand, or the target of the assay. The analyte can be a drug, biochemical substance, chemical element or compound, or cell in an organism or organic sample. An assay usually aims to measure an analyte's intensive property and express it in the relevant measurement unit (e.g. molarity, density, functional activity in enzyme international units, degree of effect in comparison to a standard, etc.). If the assay involves exogenous reactants (the reagents), then their quantities are kept fixed (or in excess) so that the quantity and quality of the target are the only limiting factors. The difference in the assay outcome is used to deduce the unknown quality ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Psittacosis
Psittacosis—also known as parrot fever, and ornithosis—is a zoonotic infectious disease in humans caused by a bacterium called '' Chlamydia psittaci'' and contracted from infected parrots, such as macaws, cockatiels, and budgerigars, and from pigeons, sparrows, ducks, hens, gulls and many other species of birds. The incidence of infection in canaries and finches is believed to be lower than in psittacine birds. In certain contexts, the word is used when the disease is carried by any species of birds belonging to the family Psittacidae, whereas ornithosis is used when other birds carry the disease. In humans Signs and symptoms In humans, psittacosis typically presents as a flu-like illness with an incubation period of 5–19 days. The severity of the disease varies, ranging from asymptomatic cases to systemic illness with severe pneumonia. Early symptoms often mimic typhoid fever and include high fevers, chills, headache, muscle aches, joint pain, diarrhea, conjunctivi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Q-fever
Q fever or query fever is a disease caused by infection with ''Coxiella burnetii'', a bacterium that affects humans and other animals. This organism is uncommon, but may be found in cattle, sheep, goats, and other domestic mammals, including cats and dogs. The infection results from inhalation of a spore-like small-cell variant, and from contact with the milk, urine, feces, vaginal mucus, or semen of infected animals. Rarely, the disease is tick-borne. The incubation period can range from . Humans are vulnerable to Q fever, and infection can result from even a few organisms. The bacterium is an obligate intracellular pathogenic parasite. Signs and symptoms The incubation period is usually two to three weeks. The most common manifestation is flu-like symptoms: abrupt onset of fever, malaise, profuse perspiration, severe headache, muscle pain, joint pain, loss of appetite, upper respiratory problems, dry cough, pleuritic pain, chills, confusion, and gastrointestina ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Australian Academy Of Science
The Australian Academy of Science was founded in 1954 by a group of distinguished Australians, including Australian Fellows of the Royal Society of London. The first president was Sir Mark Oliphant. The academy is modelled after the Royal Society and operates under a Royal charter; as such, it is an independent body, but it has government endorsement. The Academy Secretariat is in Canberra, at the #The Shine Dome, Shine Dome. The objectives of the academy are to promote science and science education through a wide range of activities. It has defined four major program areas: :* Recognition of outstanding contributions to science :* Education and public awareness :* Science policy :* International relations The academy also runs the 22 Australian Academy of Science National Committees, National Committees for Science which provide a forum to discuss issues relevant to all the scientific disciplines in Australia. Origins The Australian National Research Council (ANRC) was estab ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Walter And Eliza Hall Institute Of Medical Research
Walter may refer to: People and fictional characters * Walter (name), including a list of people and fictional and mythical characters with the given name or surname * Little Walter, American blues harmonica player Marion Walter Jacobs (1930–1968) * Gunther (wrestler), Austrian professional wrestler and trainer Walter Hahn (born 1987), who previously wrestled as "Walter" * Walter, standard author abbreviation for Thomas Walter (botanist) ( – 1789) * "Agent Walter", an early codename of Josip Broz Tito * Walter, pseudonym of the anonymous writer of '' My Secret Life'' * Walter Plinge, British theatre pseudonym used when the original actor's name is unknown or not wished to be included * John Walter (businessman), Canadian business entrepreneur Companies * American Chocolate, later called Walter, an American automobile manufactured from 1902 to 1906 * Walter Energy, a metallurgical coal producer for the global steel industry * Walter Aircraft Engines, Czech manufacturer ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |