Shiver Music
Shivering (also called shuddering) is a bodily function in response to cold and extreme fear in warm-blooded animals. When the core body temperature drops, the shivering reflex is triggered to maintain homeostasis. Skeletal muscles begin to shake in small movements, creating warmth by expending energy. Shivering can also be a response to fever, as a person may feel cold. During fever, the hypothalamic set point for temperature is raised. The increased set point causes the body temperature to rise (pyrexia), but also makes a person feel cold until the new set point is reached. Biological basis Located in the posterior hypothalamus near the wall of the third ventricle is an area called the primary motor center for shivering. This area is normally inhibited by signals from the heat center in the anterior hypothalamic-preoptic area but is excited by cold signals from the skin and spinal cord and becomes activated when the body temperature falls even a fraction of a degree below a c ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Winter's Coming (5268496779)
Winter's is a popular Peruvian brand of chocolates and other food products owned by Compañía Nacional de Chocolates de Perú S.A. History The brand was started in 1997 by Lima-based Good Foods S.A., the largest Peruvian exporter of chocolates. On 1 February 2007, Colombian-based food conglomerate Grupo Nacional de Chocolates purchased Good Foods S.A. and the Winter's brand for US$36 million through its Peruvian subsidiary Compañía Nacional de Chocolates de Perú S.A. Products Winter's has more than forty brands in its portfolio of products, including cocoas, milk modifiers, chocolates, cookies, candies, gums, lozenges, chewing gum, icings, cream confections, marshmallows, and panettone Panettone is an Italian type of sweet bread and fruitcake, originally from Milan, Italy, usually prepared and enjoyed for Christmas and New Year in Western, Southern, and Southeastern Europe, as well as in South America, Eritrea, Australia, .... * Chocopunch - A cream confecti ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Norepinephrine
Norepinephrine (NE), also called noradrenaline (NA) or noradrenalin, is an organic compound, organic chemical in the catecholamine family that functions in the brain and human body, body as a hormone, neurotransmitter and neuromodulator. The name "noradrenaline" (from Latin '':wikt:ad-, ad'', "near", and '':wikt:ren, ren'', "kidney") is more commonly used in the United Kingdom and the rest of the world, whereas "norepinephrine" (from Ancient Greek :wikt:ἐπί, ἐπῐ́ (''epí''), "upon", and :wikt:νεφρός, νεφρός (''nephrós''), "kidney") is usually preferred in the United States. "Norepinephrine" is also the international nonproprietary name given to norepinephrine (drug), the drug. Regardless of which name is used for the substance itself, parts of the body that produce or are affected by it are referred to as noradrenergic. The general function of norepinephrine is to mobilize the brain and body for action. Norepinephrine release is lowest during sleep, rise ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chattering Teeth
Chattering teeth is a bodily function in animals that occurs primarily in response to cold; the jaw muscles begin to shiver leading teeth to crash together. It may also occur as a result of bruxism where emotional stress causes the jaw movements. Certain medications can lead to teeth chattering as a side effect, especially antipsychotics and selective serotonin reuptake inhibitor Selective serotonin reuptake inhibitors (SSRIs) are a class of drugs that are typically used as antidepressants in the treatment of major depressive disorder, anxiety disorders, and other psychological conditions. SSRIs primarily work by blo ...s. References Symptoms and signs Cold Teeth {{Symptom-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Post Micturition Convulsion Syndrome
In neurourology, post-micturition convulsion syndrome (PMCS), also known informally as pee shivers or piss shivers, is the experience of shivering during or after urination. The syndrome seems to be experienced more often by men than women. The term "post-micturition convulsion syndrome" was coined in 1994 in the online question-and-answer newspaper column '' The Straight Dope'', when a reader inquired about the phenomenon. Explanation There has yet to be any peer-reviewed research on the topic. The most plausible theory is that the shiver is a result of the autonomic nervous system getting its signals mixed up between its two main divisions: *The sympathetic nervous system (SNS), which controls bladder function, preventing urination. *The parasympathetic nervous system (PNS), which relaxes the urethral sphincter and contracts the bladder, causing urination. Part of the SNS response to a full bladder is the release of catecholamines (including epinephrine, norepinephri ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Myoclonus
Myoclonus is a brief, involuntary, irregular (lacking rhythm) twitching of a muscle, a joint, or a group of muscles, different from clonus, which is rhythmic or regular. Myoclonus ( myo- "muscle", clonus "spasm") describes a medical sign and, generally, is not a diagnosis of a disease. It belongs to the hyperkinetic movement disorders, among tremor and chorea for example. These myoclonic twitches, jerks, or seizures are usually caused by sudden muscle contractions (''positive myoclonus'') or brief lapses of contraction (''negative myoclonus''). The most common circumstance under which they occur is while falling asleep ( hypnic jerk). Myoclonic jerks occur in healthy people and are experienced occasionally by everyone. However, when they appear with more persistence and become more widespread they can be a sign of various neurological disorders. Hiccups are a kind of myoclonic jerk specifically affecting the diaphragm. When a spasm is caused by another person it is kn ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Goose Bumps
Goose bumps, goosebumps or goose pimples are the bumps on a person's skin at the base of body hairs which may involuntarily develop when a person is Tickling, tickled, cold or experiencing strong emotions such as fear, euphoria or sexual arousal. The formation of goose bumps in humans under Stress (medicine), stress is considered by some to be a Vestigial response, vestigial reflex, though visible piloerection is associated with changes in skin temperature in humans. The reflex of producing goose bumps is known as piloerection or the pilomotor reflex, or, more traditionally, horripilation. It occurs in many mammals; a prominent example is porcupines, which raise their quills when threatened, or sea otters when they encounter sharks or other predators. Anatomy and biology Goose bumps are created when tiny muscles at the base of each hair, known as ''arrector pili muscles'', contract and pull the hair straight up. The reflex is started by the sympathetic nervous system, which i ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Psychogenic Shivering
Frisson ( , ; French for "shiver"), also known as aesthetic chills or psychogenic shivers, is a psychophysiological response to rewarding stimuli (including music, films, stories, people, photos, and rituals) that often induces a pleasurable or otherwise positively-valenced affective state and transient paresthesia (skin tingling or chills), sometimes along with piloerection (goose bumps) and mydriasis (pupil dilation). The sensation can occur as a mildly to moderately pleasurable emotional response to music with skin tingling. The psychological component (i.e., the pleasurable feeling) and physiological components (i.e., paresthesia, piloerection, and pupil dilation) of the response are mediated by the reward system and sympathetic nervous system, respectively. The stimuli that produce this response are specific to each individual. Frisson is of short duration, lasting only a few seconds. Typical stimuli include loud passages of music and passages—such as appoggiaturas a ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Postanesthetic Shivering
Postanesthetic shivering (PAS) is shivering after anesthesia. Description and treatment Postanesthetic shivering is one of the leading causes of discomfort in patients recovering from general anesthesia. It usually results due to the anesthetic inhibiting the body's thermoregulatory capability, although cutaneous vasodilation (triggered by post-operative pain) may also be a causative factor. First-line treatment consists of warming the patient; more persistent/severe cases may be treated with medications such as tramadol, pethidine, clonidine, and nefopam, which work by reducing the shivering threshold temperature and reducing the patient's level of discomfort. As these medications may react and/or synergize with the anesthetic agents employed during the surgery, their use is generally avoided when possible. The anesthetic ketamine can also be used to manage postanesthetic shivering. Intensity The intensity of PAS may be graded using the scale described by Crossley and Mahajan: ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Adenosine Triphosphate
Adenosine triphosphate (ATP) is a nucleoside triphosphate that provides energy to drive and support many processes in living cell (biology), cells, such as muscle contraction, nerve impulse propagation, and chemical synthesis. Found in all known forms of life, it is often referred to as the "molecular unit of currency" for intracellular energy transfer. When consumed in a Metabolism, metabolic process, ATP converts either to adenosine diphosphate (ADP) or to adenosine monophosphate (AMP). Other processes regenerate ATP. It is also a Precursor (chemistry), precursor to DNA and RNA, and is used as a coenzyme. An average adult human processes around 50 kilograms (about 100 mole (unit), moles) daily. From the perspective of biochemistry, ATP is classified as a nucleoside triphosphate, which indicates that it consists of three components: a nitrogenous base (adenine), the sugar ribose, and the Polyphosphate, triphosphate. Structure ATP consists of three parts: a sugar, an amine base ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Proton Electromotive Force
An electrochemical gradient is a gradient of electrochemical potential, usually for an ion that can move across a membrane. The gradient consists of two parts: * The chemical gradient, or difference in solute concentration across a membrane. * The electrical gradient, or difference in charge across a membrane. If there are unequal concentrations of an ion across a permeable membrane, the ion will move across the membrane from the area of higher concentration to the area of lower concentration through simple diffusion. Ions also carry an electric charge that forms an electric potential across a membrane. If there is an unequal distribution of charges across the membrane, then the difference in electric potential generates a force that drives ion diffusion until the charges are balanced on both sides of the membrane. Electrochemical gradients are essential to the operation of batteries and other electrochemical cells, photosynthesis and cellular respiration, and certain other bi ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mitochondria
A mitochondrion () is an organelle found in the cells of most eukaryotes, such as animals, plants and fungi. Mitochondria have a double membrane structure and use aerobic respiration to generate adenosine triphosphate (ATP), which is used throughout the cell as a source of chemical energy. They were discovered by Albert von Kölliker in 1857 in the voluntary muscles of insects. The term ''mitochondrion'', meaning a thread-like granule, was coined by Carl Benda in 1898. The mitochondrion is popularly nicknamed the "powerhouse of the cell", a phrase popularized by Philip Siekevitz in a 1957 ''Scientific American'' article of the same name. Some cells in some multicellular organisms lack mitochondria (for example, mature mammalian red blood cells). The multicellular animal '' Henneguya salminicola'' is known to have retained mitochondrion-related organelles despite a complete loss of their mitochondrial genome. A large number of unicellular organisms, such as microspo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Glycerol
Glycerol () is a simple triol compound. It is a colorless, odorless, sweet-tasting, viscous liquid. The glycerol backbone is found in lipids known as glycerides. It is also widely used as a sweetener in the food industry and as a humectant in pharmaceutical formulations. Because of its three hydroxyl groups, glycerol is miscible with water and is Hygroscopy, hygroscopic in nature. Modern use of the word glycerine (alternatively spelled glycerin) refers to commercial preparations of less than 100% purity, typically 95% glycerol. Structure Although chirality, achiral, glycerol is prochirality, prochiral with respect to reactions of one of the two primary alcohols. Thus, in substituted derivatives, the Glycerophospholipid#Nomenclature and stereochemistry, stereospecific numbering labels the molecule with a ''sn''- prefix before the stem name of the molecule. Production Natural sources Glycerol is generally obtained from plant and animal sources where it occurs in triglycerides, est ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |