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Self-experiment
Self-experimentation refers to single-subject research in which the experimenter conducts the experiment on themself. Usually this means that a single person is the designer, operator, subject, analyst, and user or reporter of the experiment. Also referred to as Personal science or N-of-1 research, self-experimentation is an example of citizen science, since it can also be led by patients or people interested in their own health and well-being, as both research subjects and self-experimenters. Biology and medicine Human scientific self-experimentation principally (though not necessarily) falls into the fields of medicine and psychology. Self-experimentation has a long and well-documented history in medicine which continues to the present day. For example, after failed attempts to infect piglets in 1984, Barry Marshall drank a petri dish of ''Helicobacter pylori'' from a patient, and soon developed gastritis, achlorhydria, stomach discomfort, nausea, vomiting, and halitosis. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Seth Roberts
Seth Roberts (August 17, 1953 – April 26, 2014) was a professor of psychology at Tsinghua University in Beijing and emeritus professor of psychology at the University of California, Berkeley. A prolific blogger, He was the author of the bestselling book '' The Shangri-La Diet.''Dubner and Levit"Does the Truth Lie Within? The Accidental Diet" September 11, 2005. on SethRoberts.net He was well known for his work in self-experimentation which led to many discoveries, including his personal diet, multiple publications and his expansive blog.Frauenfelder, Mar Seth Roberts' fascinating ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychedelic Drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic hallucinogens or serotonergic hallucinogens, the term ''psychedelic'' is sometimes used more broadly to include various other types of hallucinogens as well, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively. Classic psychedelics generally cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, LSD, psilocybin, and DMT. There are a large number of both naturally occurring and synthetic serotonergic psychedelics. Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Personal Science
Personal science is a term used by the late psychologist and scientist Seth Roberts, who defined it as: "''using science to solve your own problems''". Associated fields are self-experimentation and citizen science. The concept has been further developed within the Quantified Self community. The first use of the term in a scientific publication was in 2016, where it was associated with: "''an interest in collecting data about their own bodies or lives in order to obtain insights into their everyday health or performance".'' In 2017, the scientific journal '' Methods of Information in Medicine'' published a focus theme on single subject (N-of-1) research design, which also included personal science. The editorial introducing the focus theme is titled "''Single Subject (N-of-1) Research Design, Data Processing, and Personal Science"'' is co-authored by Gary Wolf, who together with Kevin Kelly coined the phrase ''the quantified self''. In the editorial, personal science was described ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychonautics
Psychonautics (from the Ancient Greek ' 'soul, spirit, mind' and ' 'sailor, navigator') refers both to a methodology for describing and explaining the subjective effects of altered states of consciousness, including those induced by meditation or mind-altering substances, and to a research group in which the researcher voluntarily immerses themselves into an altered mental state in order to explore the accompanying experiences. The term has been applied diversely, to cover all activities by which altered states are induced and utilized for spiritual purposes or the exploration of the human condition, including shamanism, lamas of the Tibetan Buddhist tradition,As noted by the Siddhars of Ancient India, sensory deprivation, and archaic/modern drug users who use entheogenic substances in order to gain deeper insights and spiritual experiences. Self-experimentation of psychedelics in groups may foster innovation of alternative medication treatment. A person who uses altered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and pharmacology of such agents—in his mid-life and later, many through preparation in his home laboratory, and testing on himself. He is acknowledged to have introduced to broader use, in the late 1970s, the previously-synthesized compound MDMA ("ecstasy"), in research psychopharmacology and in combination with conventional therapy, the latter through presentations and academic publications, including to psychologists; and for the rediscovery, occasional discovery, and regular synthesis and personal use and distribution, of possibly hundreds of Psychoactive drug, psychoactive compounds (for their Psychedelic drug, psychedelic and MDMA-like empathogenic bioactivity, bioactivities). As such, Shulgin is seen both as a pioneering and a controversi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Single-subject Research
Single-subject research is a group of research methods that are used extensively in the experimental analysis of behavior and applied behavior analysis with both human and non-human participants. This research strategy focuses on one participant and tracks their progress in the research topic over a period of time. Single-subject research allows researchers to track changes in an individual over a large stretch of time instead of observing different people at different stages. This type of research can provide critical data in several fields, specifically psychology. It is most commonly used in experimental and applied analysis of behaviors. This research has been heavily debated over the years. Some believe that this research method is not effective at all while others praise the data that can be collected from it. Principal methods in this type of research are: A-B-A-B designs, Multi-element designs, Multiple Baseline designs, Repeated acquisition designs, Brief experimental desi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Acesulfame Potassium
Acesulfame potassium (, or ), also known as acesulfame K or Ace K, is a synthetic calorie-free sugar substitute (artificial sweetener) often marketed under the trade names Sunett and Sweet One. In the European Union, it is known under the E number (additive code) E950. It was discovered accidentally in 1967 by German chemist Karl Clauss at Hoechst AG (now Nutrinova). Acesulfame potassium is the potassium salt of 6-methyl-1,2,3-oxathiazine-4(3''H'')-one 2,2-dioxide. It is a white crystalline powder with molecular formula and a molecular weight of 201.24 g/mol. Properties Acesulfame K is 200 times sweeter than sucrose (common sugar), as sweet as aspartame, about two-thirds as sweet as saccharin, and one-third as sweet as sucralose. Like saccharin, it has a slightly bitter aftertaste, especially at high concentrations. Kraft Foods patented the use of sodium ferulate to mask acesulfame's aftertaste. Acesulfame K is often blended with other sweeteners (usually sucralose ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Enhancement
Human enhancement is the natural, artificial, or technological alteration of the human body in order to enhance physical or mental capabilities. Technologies Existing technologies Three forms of human enhancement currently exist: reproductive, physical, and mental. Reproductive enhancements include embryo selection by preimplantation genetic diagnosis, cytoplasmictransfer, and in vitro-generated gametes. Physical enhancements include cosmetics ( plastic surgery and orthodontics), Drug-induced (doping and performance-enhancing drugs), functional (prosthetics and powered exoskeletons), Medical ( implants (e.g. pacemaker) and organ replacements (e.g. bionic lenses)), and strength training (weights (e.g. barbells) and dietary supplement)). Examples of mental enhancements are nootropics, neurostimulation, and supplements that improve mental functions. Computers, mobile phones, and Internet can also be used to enhance cognitive efficiency. Notable efforts in human augmentation are ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Participant Observation
Participant observation is one type of data collection method by practitioner-scholars typically used in qualitative research and ethnography. This type of methodology is employed in many disciplines, particularly anthropology (including cultural anthropology and ethnology), sociology (including sociology of culture and cultural criminology), communication studies, human geography, and social psychology. Its aim is to gain a close and intimate familiarity with a given group of individuals (such as a religious, occupational, youth group, or a particular community) and their practices through an intensive involvement with people in their cultural environment, usually over an extended period of time. The concept "participant observation" was first coined in 1924 by Eduard C. Lindeman (1885-1953), an American pioneer in adult education influenced by John Dewey and Danish educator-philosopher N.F.S.Grundtvig, in his 1925 book ''Social Discovery: An Approach to the Study of Func ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ann Shulgin
Laura Ann Shulgin ( Gotlieb; March 22, 1931 – July 9, 2022) was an American author and the wife of chemist Alexander Shulgin, with whom she wrote ''PiHKAL'' and '' TiHKAL''. Life and career Laura Ann Gotlieb Detailed biography of Ann Shulgin was born in Wellington, New Zealand, to parents Bernard Gotlieb and Gwen Ormiston, but grew up in the village Opicina outside the Italian city Trieste. Her father was U.S. Consul in Trieste for six years before World War II. Later in her childhood she lived in the U.S., Cuba, and Canada. She studied art and became an artist, married an artist and had a child, and they later divorced. She had two more marriages ending in divorce and had three more children. Ann went back to work as a medical transcriber, and met Alexander ("Sasha") Shulgin in 1978; they were married on 4 July 1981 in their back yard. She worked as a lay therapist with psychedelic substances such as MDMA and 2C-B in therapeutic settings while these drugs were still legal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
History Of Lysergic Acid Diethylamide
The psychedelic drug (or entheogen) lysergic acid diethylamide (LSD) was first synthesized on November 16, 1938, by the Swiss chemist Albert Hofmann in the Sandoz laboratories in Basel, Switzerland.Albert Hofmann; translated from the original German (LSD Ganz Persönlich) by J. OttMAPS-Volume 6, Number 69, Summer 1969 It was not until five years later on April 19, 1943, that the psychedelic properties were found. Discovery Albert Hofmann, born in Switzerland, joined the pharmaceutical-chemical department of Sandoz Laboratories, located in Basel, as a co-worker with professor Arthur Stoll, founder and director of the pharmaceutical department. He began studying the medicinal plant squill and the fungus ergot as part of a program to purify and synthesize active constituents for use as pharmaceuticals. His main contribution was to elucidate the chemical structure of the common nucleus of ''Scilla'' glycosides (an active principle of Mediterranean squill). While researching lyse ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Hofmann
Albert Hofmann (11 January 1906 – 29 April 2008) was a Swiss chemist known for being the first to synthesize, ingest, and learn of the psychedelic effects of lysergic acid diethylamide (LSD). Hofmann's team also isolated, named and synthesized the principal psychedelic mushroom compounds psilocybin and psilocin. He authored more than 100 scientific articles and numerous books, including ''LSD: Mein Sorgenkind'' (''LSD: My Problem Child''). In 2007, he shared first place with Tim Berners-Lee on a list of the 100 greatest living geniuses published by ''The Daily Telegraph'' newspaper. Early life and education Albert Hofmann was born in Baden, Switzerland, on 11 January 1906. He was the first of four children to factory toolmaker Adolf Hofmann and Elisabeth ( Schenk) and was baptized Protestant. When his father became ill, Hofmann obtained a position as a commercial apprentice in concurrence with his studies. Owing to his father's low income, Albert's godfather paid for his e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
