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Scutellaria Pekinensis
''Scutellaria'' is a genus of flowering plants in the Mentha, mint family, Lamiaceae. They are known commonly as skullcaps. The generic name is derived from the Latin ''scutella'', meaning "a small dish, tray or platter",''Scutellaria parvula'' var. ''missouriensis''. Robert W. Freckmann Herbarium. University of Wisconsin, Stevens Point. or "little dish", referring to the shape of the Sepal, calyx. The common name alludes to the resemblance of the same structure to "miniature Cervelliere, medieval helmets". The genus has a cosmopolitan distribution, subcosmopolitan distribution,Ulloa, C. U. and P. M. Jørgensen [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Traditional Chinese Medicine
Traditional Chinese medicine (TCM) is an alternative medicine, alternative medical practice drawn from traditional medicine in China. A large share of its claims are pseudoscientific, with the majority of treatments having no robust evidence of effectiveness or logical mechanism of action. Some TCM ingredients Traditional Chinese medicine#Safety, are known to be toxic and cause disease, including cancer. Medicine in traditional China encompassed a range of sometimes competing health and healing practices, folk beliefs, Scholar-official, literati theory and Confucianism, Confucian philosophy, Chinese herbology, herbal remedies, Chinese food therapy, food, diet, exercise, medical specializations, and schools of thought. TCM as it exists today has been described as a largely 20th century invention. In the early twentieth century, Chinese cultural and political modernizers worked to eliminate traditional practices as backward and unscientific. Traditional practitioners then selec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scutellaria Albida
''Scutellaria'' is a genus of flowering plants in the mint family, Lamiaceae. They are known commonly as skullcaps. The generic name is derived from the Latin ''scutella'', meaning "a small dish, tray or platter",''Scutellaria parvula'' var. ''missouriensis''. Robert W. Freckmann Herbarium. University of Wisconsin, Stevens Point. or "little dish", referring to the shape of the calyx. The common name alludes to the resemblance of the same structure to "miniature ". The genus has a [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scutellaria Alabamensis
''Scutellaria alabamensis'', known as Alabama skullcap, is a rare and endangered wildflower, endemic only to 9 counties in North central Alabama. Description Alabama skullcap is an erect Perennial plant, perennial herb, usually 4.5–6 cm tall, that produces blue and white flowers in an elongated cluster (rarely, flanked by 2 lateral clusters). Blooms early June-early July. It is one of 300-400 members of the ''Scutellaria'' genus of flowering plants, commonly known as skullcaps. The skullcap name is because of the resemblance to medieval helmets. References External links * https://davesgarden.com/guides/pf/go/238086/#b {{Taxonbar, from=Q15364530 Scutellaria, alabamensis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Scutellarein
Scutellarein is a flavone that can be found in ''Scutellaria lateriflora'' and other members of the genus ''Scutellaria'', as well as the fern '' Asplenium belangeri''. Glycosides The scutellarin (Scutellarein-7-glucuronide A glucuronide, also known as glucuronoside, is any substance produced by linking glucuronic acid to another substance via a glycosidic bond. The glucuronides belong to the glycosides. Glucuronidation, the conversion of chemical compounds to glucu ...) is transformed by hydrolysis into scutellarein. References Flavones Pyrogallols Tetrols {{Aromatic-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oroxylin A
Oroxylin A is an O-methylated flavone, a chemical compound that can be found in the medicinal plants ''Scutellaria baicalensis'' and ''Scutellaria lateriflora'', and the '' Oroxylum indicum'' tree. It has demonstrated activity as a dopamine reuptake inhibitor, and is also a negative allosteric modulator of the benzodiazepine site of the GABAA receptor. Oroxylin A has been found to improve memory consolidation in mice by elevating brain-derived neurotrophic factor (BDNF) levels in the hippocampus. See also * Baicalin * Baicalein * ''Chaenomeles speciosa'' * Urolithin A Urolithin A is a metabolite compound resulting from the transformation of ellagitannins by the gut bacteria. It belongs to the class of organic compounds known as benzo-coumarins or dibenzo-α-pyrones. Its precursors – ellagic acids and ellagit ... * 5,7-Dihydroxy-6-methoxy-2-(4-phenoxyphenyl)chromen-4-one References {{GABA receptor modulators O-methylated flavones Resorcinols Dopamine reuptake inhib ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Apigenin
Apigenin (4′,5,7-trihydroxyflavone), found in many plants, is a flavone compound that is the aglycone of several naturally occurring glycosides. It is a yellow crystalline solid that has been used to dye wool. Apigenin is abundant in parsley, celery, celeriac, and chamomile flowers. It occurs in many fruits and vegetables, with the highest concentrations in dried and fresh parsley. Sources in nature Apigenin is found in many fruits and vegetables, but parsley, celery, celeriac, and chamomile tea are the most common sources. Apigenin is particularly abundant in the flowers of chamomile plants, constituting 68% of total flavonoids. Dried parsley can contain about 45 mg apigenin per gram. The apigenin content of fresh parsley is reportedly 215 mg per 100 grams, which is much higher than the next highest food source. Pharmacology ''In vitro'', apigenin binds competitively to the benzodiazepine site on GABAA receptors. There exist conflicting findings regard ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Baicalin
As baicalin is a flavone glycoside, it is a flavonoid. It is the glucuronide of baicalein. Natural occurrences Baicalin is found in several species in the genus ''Scutellaria'', including ''Scutellaria baicalensis'', and ''Scutellaria lateriflora''. There are 10 mg/g baicalin in ''Scutellaria galericulata'' leaves.P.H. and Horhammer, L., Hager's Handbuch der Pharmazeutischen Praxis, Vols. 2-6, Springer-Verlag, Berlin, 1969-1979 It is also present in the bark isolate of the ''Oroxylum indicum'' tree. Medical uses Baicalin is one of the chemical ingredients of at least two herbal supplements: Shuanghuanglian and Sho-Saiko-To, which is a Chinese classic herbal formula, and listed in Japan as Kampo list, Kampo medicine. Baicalin, along with its aglycone baicalein, is a positive allosteric modulator of the benzodiazepine site and/or a non-benzodiazepine site of the GABAA receptor, GABAA receptor. In mice, baicalin produces anxiolytic effects without sedative or myorelaxant e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wogonoside
Wogonin is an ''O''-methylated flavone, a flavonoid-like chemical compound which is found in ''Scutellaria baicalensis''. The glycosides of wogonin are known as wogonosides. For example, oroxindin is a wogonin glucuronide isolated from '' Oroxylum indicum''. It is one of the active ingredients of Sho-Saiko-To, a Japanese herbal supplement. Pharmacology Wogonin has been found in one study to have anxiolytic properties in mice at doses of 7.5 to 30 mg/kg, without exhibiting the sedative and muscle-relaxing properties of benzodiazepines. Preliminary ''in vitro'' studies have shown pharmacological effects that indicate wogonin may have anti-tumor properties. Wogonin has also been found to possess anticonvulsant effects. It acts as a positive allosteric modulator of the benzodiazepine site of the GABAA receptor with a binding affinity of Ki 0.92 μM and an IC50 value of 1.26 μM which is about 100 times less potent than diazepam Diazepam, sold under the br ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Flavonoid
Flavonoids (or bioflavonoids; from the Latin word ''flavus'', meaning yellow, their color in nature) are a class of polyphenolic secondary metabolites found in plants, and thus commonly consumed in the diets of humans. Chemically, flavonoids have the general structure of a 15-carbon skeleton, which consists of two phenyl rings (A and B) and a Heterocyclic compound, heterocyclic ring (C, the ring containing the embedded oxygen). This carbon structure can be abbreviated C6-C3-C6. According to the IUPAC nomenclature, they can be classified into: *flavonoids or bioflavonoids *isoflavonoids, derived from 3-phenylchromone, chromen-4-one (3-phenyl-1,4-benzopyran, benzopyrone) structure *neoflavonoids, derived from 4-phenylcoumarin (4-phenyl-1,2-benzopyran, benzopyrone) structure The three flavonoid classes above are all ketone-containing compounds and as such, anthoxanthins (flavones and flavonols). This class was the first to be termed bioflavonoids. The terms flavonoid and bioflavo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rabies
Rabies is a viral disease that causes encephalitis in humans and other mammals. It was historically referred to as hydrophobia ("fear of water") because its victims panic when offered liquids to drink. Early symptoms can include fever and abnormal sensations at the site of exposure. These symptoms are followed by one or more of the following symptoms: nausea, vomiting, violent movements, uncontrolled excitement, fear of water, an inability to move parts of the body, confusion, and loss of consciousness. Once symptoms appear, the result is virtually always death. The time period between contracting the disease and the start of symptoms is usually one to three months but can vary from less than one week to more than one year. The time depends on the distance the virus must travel along Peripheral nervous system, peripheral nerves to reach the central nervous system. Rabies is caused by lyssaviruses, including the rabies virus and Australian bat lyssavirus. It is spread when an i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
