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Salmonella Enterica
''Salmonella enterica'' (formerly ''Salmonella choleraesuis'') is a rod-shaped, flagellate, facultative anaerobic, Gram-negative bacterium and a species of the genus ''Salmonella''. It is divided into six subspecies, arizonae (IIIa), diarizonae (IIIb), houtenae (IV), salamae (II), indica (VI), and enterica (I). A number of its serovars are serious human pathogens; many of them are (more specifically) serovars of ''Salmonella enterica'' subsp. ''enterica''. Epidemiology Most cases of salmonellosis are caused by food infected with ''S. enterica'', which often infects cattle and poultry, though other animals such as domestic cats and hamsters have also been shown to be sources of infection in humans. It primarily resides in the intestinal tract of animals and humans and can be found in feedstuff, soil, bedding, litter, and fecal matter. The primary reservoir for the pathogen is poultry and 70% of human cases are attributed to the consumption of contaminated eggs, chicken, or ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hektoen Enteric Agar
Hektoen enteric agar (HEK, HE or HEA) is a selective and differential agar primarily used to recover '' Salmonella'' and '' Shigella'' from patient specimens. HEA contains indicators of lactose fermentation and hydrogen sulfide production; as well as inhibitors to prevent the growth of Gram-positive bacteria. It is named after the Hektoen Institute in Chicago, where researchers developed the agar. Use The definitive use of HEA is to discriminate between ''Shigella'' and ''Salmonella'', although many other species may grow on these plates. However, while the other bacteria may be clinically relevant, the assay does not discriminate among them. Effectively, HEA uses a metabolic assay to divide colonies into "''Salmonella'' and ''Shigella''" and "everything else". Use of these plates assumes that the user is not interested in other enteric pathogens such as '' Klebsiella'' or '' Escherichia''. The plates contain various sugar sources ( lactose, sucrose, and salicin), none o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pasteurization
In food processing, pasteurization (American and British English spelling differences#-ise, -ize (-isation, -ization), also pasteurisation) is a process of food preservation in which packaged foods (e.g., milk and fruit juices) are treated with mild heat, usually to less than , to eliminate pathogens and extend shelf life. Pasteurization either destroys or deactivates microorganisms and enzymes that contribute to food spoilage or the risk of disease, including vegetative bacteria, but most Endospore, bacterial spores survive the process. Pasteurization is named after the French microbiologist Louis Pasteur, whose research in the 1860s demonstrated that thermal processing would deactivate unwanted microorganisms in wine. Spoilage enzymes are also inactivated during pasteurization. Today, pasteurization is used widely in the dairy industry and other food processing industries for food preservation and food safety. By the year 1999, most liquid products were heat treated in a co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathogenesis
In pathology, pathogenesis is the process by which a disease or disorder develops. It can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance. The word comes . Description Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown. For example, bacterial pathogenesis is the process by which bacteria cause infectious illness. Most diseases are caused by multiple processes. For example, certain cancers arise from dysfunction of the immune system (skin tumors and lymphoma after a renal transplant, which requires immunosuppression), '' Streptococcus pneumoniae'' is spread through contact with respiratory secretions, such as saliva, mucus, or cough droplets from an infected person and colonizes the upper respiratory tract and begins to multiply. The pathogenic mechanisms of a disease (or condition) are set in motion by the underlying causes, which if controlled woul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arizona
Arizona is a U.S. state, state in the Southwestern United States, Southwestern region of the United States, sharing the Four Corners region of the western United States with Colorado, New Mexico, and Utah. It also borders Nevada to the northwest and California to the west, and shares Mexico-United States border, an international border with the Mexican states of Sonora and Baja California to the south and southwest. Its Capital city, capital and List of largest cities, largest city is Phoenix, Arizona, Phoenix, which is the most populous state capital and list of United States cities by population, fifth most populous city in the United States. Arizona is divided into 15 List of counties in Arizona, counties. Arizona is the list of U.S. states and territories by area, 6th-largest state by area and the list of U.S. states and territories by population, 14th-most-populous of the 50 states. It is the 48th state and last of the contiguous United States, contiguous states to be a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pathogenic Bacteria
Pathogenic bacteria are bacteria that can cause disease. This article focuses on the bacteria that are pathogenic to humans. Most species of bacteria are harmless and many are Probiotic, beneficial but others can cause infectious diseases. The number of these pathogenic species in humans is estimated to be fewer than a hundred. By contrast, several thousand species are considered part of the gut flora, with a few hundred species present in each individual human's digestive tract. The body is continually exposed to many species of bacteria, including beneficial commensals, which grow on the skin and mucous membranes, and saprophytes, which grow mainly in the soil and in decomposition, decaying matter. The blood and tissue fluids contain nutrients sufficient to sustain the growth of many bacteria. The body has defence mechanisms that enable it to resist microbial invasion of its tissues and give it a natural immune system, immunity or innate immunity, innate resistance against man ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salmonella Bongori
''Salmonella bongori'' is a pathogenic bacterium belonging to the genus ''Salmonella'', and was earlier known as ''Salmonella'' subspecies V or '' S. enterica'' subsp. ''bongori'' or ''S. choleraesuis'' subsp. ''bongori''. It is a gram-negative, rod-shaped bacterium (bacillus), which causes a gastrointestinal disease called salmonellosis, characterized by cramping and diarrhoea. It is typically considered a microbe of cold-blooded animals, unlike other members of the genus, and is most frequently associated with reptiles. It was discovered in 1966 from a lizard in the city of Bongor, Chad, from which the specific name ''bongori'' was derived. After decades of controversy in ''Salmonella'' nomenclature, it gained the species status in 2005. Pathogenicity and epidemiology ''S. bongori'' is classically regarded as the ''Salmonella'' of lizards. However, discrete investigations contradict the notion of strict host-specificity, as reports emerged of occurrence in dogs and b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Typhoid Fever
Typhoid fever, also known simply as typhoid, is a disease caused by '' Salmonella enterica'' serotype Typhi bacteria, also called ''Salmonella'' Typhi. Symptoms vary from mild to severe, and usually begin six to 30 days after exposure. Often there is a gradual onset of a high fever over several days. This is commonly accompanied by weakness, abdominal pain, constipation, headaches, and mild vomiting. Some people develop a skin rash with rose colored spots. In severe cases, people may experience confusion. Without treatment, symptoms may last weeks or months. Diarrhea may be severe, but is uncommon. Other people may carry it without being affected, but are still contagious. Typhoid fever is a type of enteric fever, along with paratyphoid fever. ''Salmonella enterica'' Typhi is believed to infect and replicate only within humans. Typhoid is caused by the bacterium ''Salmonella enterica'' subsp. ''enterica'' serovar Typhi growing in the intestines, Peyer's patches, mesen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fluoroquinolone
Quinolone antibiotics constitute a large group of broad-spectrum bacteriocidals that share a bicyclic core structure related to the substance 4-quinolone. They are used in human and veterinary medicine to treat bacterial infections, as well as in animal husbandry, specifically poultry production. Quinolone antibiotics are classified into four generations based on their spectrum of activity and chemical modifications. The first-generation quinolones, such as nalidixic acid, primarily target Gram-negative bacteria and are mainly used for urinary tract infections. Second-generation quinolones introduced fluorine atoms into their structure, creating fluoroquinolones, which significantly expanded their antibacterial activity to include some Gram-positive bacteria. Third-generation fluoroquinolones further improved Gram-positive coverage, while fourth-generation fluoroquinolones offer broad-spectrum activity, including anaerobic bacteria. Only quinolone antibiotics in generati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy, treatment and antibiotic prophylaxis, prevention of such infections. They may either bactericide, kill or bacteriostatic agent, inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the ones which cause the common cold or influenza. Drugs which inhibit growth of viruses are termed antiviral drugs or antivirals. Antibiotics are also not effective against fungi. Drugs which inhibit growth of fungi are called antifungal drugs. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek language, Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunosuppression
Immunosuppression is a reduction of the activation or efficacy of the immune system. Some portions of the immune system itself have immunosuppressive effects on other parts of the immune system, and immunosuppression may occur as an adverse reaction to treatment of other conditions. In general, deliberately induced immunosuppression is performed to prevent the body from rejecting an organ transplant. Additionally, it is used for treating graft-versus-host disease after a bone marrow transplant, or for the treatment of auto-immune diseases such as systemic lupus erythematosus, rheumatoid arthritis, Sjögren's syndrome, or Crohn's disease. This is typically done using medications, but may involve surgery (splenectomy), plasmapheresis, or radiation. A person who is undergoing immunosuppression, or whose immune system is weak for some other reasons (such as chemotherapy or HIV), is said to be ''immunocompromised''. Deliberately induced Administration of immunosuppressive medi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New Spain
New Spain, officially the Viceroyalty of New Spain ( ; Nahuatl: ''Yankwik Kaxtillan Birreiyotl''), originally the Kingdom of New Spain, was an integral territorial entity of the Spanish Empire, established by Habsburg Spain. It was one of several domains established during the Spanish colonization of the Americas, Spanish conquest of the Americas, and had its capital in Mexico City. Its jurisdiction comprised a large area of the southern and western portions of North America, mainly what became Mexico and the Southwestern United States, but also California, Florida and Louisiana (New Spain), Louisiana; Central America as Mexico, the Caribbean like Hispaniola and Martinique, Martinica, and northern parts of South America, even Colombia; several Pacific archipelagos, including the Philippines and Guam. Additional Asian colonies included "Spanish Formosa", on the island of Taiwan. After the 1521 Spanish conquest of the Aztec Empire, conqueror Hernán Cortés named the territory New S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cocoliztli
The Cocoliztli Epidemic or the Great Pestilence was an outbreak of a mysterious illness characterized by high fevers and bleeding which caused 5–15 million deaths in New Spain during the 16th century. The Aztec people called it ''cocoliztli'', Nahuatl for pestilence. It ravaged the Mexican highlands in epidemic proportions, resulting in the demographic collapse of some Indigenous populations. Based on the death toll, this outbreak is often referred to as the worst epidemic in the history of Mexico. Subsequent outbreaks continued to baffle both Spanish and native doctors, with little consensus among modern researchers on the pathogenesis. However, recent bacterial genomic studies have suggested that Salmonella, specifically a serotype of ''Salmonella enterica'' known as Paratyphi C, was at least partially responsible for this initial outbreak. Others believe ''cocoliztli'' was caused by an indigenous viral hemorrhagic fever, perhaps exacerbated by the worst droughts to affect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
