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Sahachiro Hata
was a prominent Japanese bacteriologist who researched the bubonic plague under Kitasato Shibasaburō and assisted in developing the antisyphilitic drug arsphenamine in 1909 in the laboratory of Paul Ehrlich. Hata received three unsuccessful nominations for the Nobel Prize, one from Swiss surgeon Emil Kocher for Chemistry in 1911 and two by Japanese colleagues Hayazo Ito and G Osawa for Physiology or Medicine in 1912 and 1913, respectively. Early life Hata was born in Tsumo Village, Shimane prefecture (now part of Masuda City) as the eighth son of the Yamane family. At the age of 14, he was adopted by the Hata family, whose male members were doctors from generation to generation. Hata completed his medical education in Okayama at the Third Higher School of Medicine (now Okayama University School of Medicine). In 1897, he became an assistant at Okayama Prefectural Hospital where he learned internal medicine from Zenjiro Inoue and biochemistry from Torasaburo Araki. Plague re ...
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Masuda, Shimane
is a Cities of Japan, city located in Shimane Prefecture, Japan. , the city had an estimated population of 43,885 in 21,249 households and a population density of 60 persons per km2. The total area of the city is . Geography Masuda is located on the western edge of Honshu, facing the Sea of Japan to the north and the Chugoku Mountains to the south and is bordered by Yamaguchi Prefecture to the west and Hiroshima Prefecture to the southwest. The city has the largest geographic area among municipalities in Shimane Prefecture. The urban center is on a narrow floodplain between the Takatsu River and the Masuda River. Parts of the southern region of the city are within the borders of the Nishi-Chugoku Sanchi Quasi-National Park. Neighboring municipalities Hiroshima Prefecture *Akiōta, Hiroshima, Akiōta *Hatsukaichi, Hiroshima, Hatsukaichi *Kitahiroshima, Hiroshima, Kitahiroshima Shimane Prefecture *Hamada, Shimane, Hamada *Tsuwano, Shimane, Tsuwano *Yoshika, Shimane, Yoshika Yama ...
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Shimane Prefecture
is a Prefectures of Japan, prefecture of Japan located in the Chūgoku region of Honshu. Shimane Prefecture is the List of Japanese prefectures by population, second-least populous prefecture of Japan at 665,205 (February 1, 2021) and has a geographic area of 6,708.26 Square kilometre, km2. Shimane Prefecture borders Yamaguchi Prefecture to the southwest, Hiroshima Prefecture to the south, and Tottori Prefecture to the east. Matsue is the capital and largest city of Shimane Prefecture, with other major cities including Izumo, Shimane, Izumo, Hamada, Shimane, Hamada, and Masuda, Shimane, Masuda. Shimane Prefecture contains the majority of the Lake Shinji-Nakaumi metropolitan area centered on Matsue, and with a population of approximately 600,000 is Japan's third-largest metropolitan area on the Sea of Japan coast after Niigata (city), Niigata and Greater Kanazawa. Shimane Prefecture is bounded by the Sea of Japan coastline on the north, where two-thirds of the population live, a ...
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Trypanosomatida
Trypanosomatida is a group of kinetoplastid unicellular organisms distinguished by having only a single flagellum. The name is derived from the Greek ''trypano'' (borer) and ''soma'' (body) because of the corkscrew-like motion of some trypanosomatid species. All members are exclusively parasitic, found primarily in insects. A few genera have life-cycles involving a secondary host, which may be a vertebrate, invertebrate or plant. These include several species that cause major diseases in humans. Some trypanosomatida are intracellular parasites, with the important exception of ''Trypanosoma brucei''. Medical importance The three major human diseases caused by trypanosomatids are; African trypanosomiasis (African trypanosomiasis, sleeping sickness, caused by ''Trypanosoma brucei'' and transmitted by Tsetse fly, tsetse flies), South American trypanosomiasis (Chagas disease, caused by ''Trypanosoma cruzi, T. cruzi'' and transmitted by Triatominae, triatomine bugs), and leishmanias ...
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Mercury (element)
Mercury is a chemical element; it has Symbol (chemistry), symbol Hg and atomic number 80. It is commonly known as quicksilver. A Heavy metal element, heavy, silvery d-block element, mercury is the only metallic element that is known to be liquid at standard temperature and pressure; the only other element that is liquid under these conditions is the halogen bromine, though metals such as caesium, gallium, and rubidium melt just above room temperature. Mercury occurs in deposits throughout the world mostly as cinnabar (mercuric sulfide). The red pigment vermilion is obtained by Mill (grinding), grinding natural cinnabar or synthetic mercuric sulfide. Exposure to mercury and mercury-containing organic compounds is toxic to the nervous system, immune system and kidneys of humans and other animals; mercury poisoning can result from exposure to water-soluble forms of mercury (such as mercuric chloride or methylmercury) either directly or through mechanisms of biomagnification. Mercu ...
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Erich Hoffmann
Erich Hoffmann (25 April 1868 – 8 May 1959) was a German dermatologist who was a native of Witzmitz, Pomerania. He studied medicine at the Berlin Military Academy, and was later a professor at the Universities of Halle and Bonn. Hoffmann is remembered for his research performed with zoologist Fritz Schaudinn (1871-1906) at the Charité Clinic in Berlin. In 1905 Schaudinn and Hoffmann discovered the bacterium that was responsible for syphilis, a spiral-shaped spirochete called ''Treponema pallidum'', which they first called ''Spirochaeta pallida''. The organism was removed from a papule in the vulva of a woman with secondary syphilis. The two doctors documented their findings in a treatise called ''Vorläufiger Bericht über das Vorkommen von Spirochaeten in syphilitischen Krankheitsprodukten und bei Papillome''.Fritz Richard Schaudinn, Erich Hoffmann: Vorläufiger Bericht über das Vorkommen von Spirochaeten in syphilitischen Krankheitsprodukten und bei Papillomen. Arbeit ...
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Fritz Schaudinn
Fritz Richard Schaudinn (19 September 1871 – 22 June 1906) was a German zoologist. Born in Röseningken (now in Ozyorsky District) in the Province of Prussia, he co-discovered, with Erich Hoffmann in 1905, the causative agent of syphilis, ''Spirochaeta pallida'' (also known as ''Treponema pallidum''). The work was carried out at the Berlin Charité. Among Schaudinn's other contributions to medicine include his work in the field of amoebic dysentery, sleeping sickness and his confirmation of the work of Sir Ronald Ross and Giovanni Battista Grassi (1854–1925) in the field of malaria research. He also demonstrated that human hookworm infection is contracted through the skin of the feet. He made noted contributions to zoology and was one of the developers of protozoology as an experimental science. Schaudinn was a graduate in zoology of the Friedrich Wilhelm University in Berlin. Since 2002 an annual medical prize has been awarded in his name. In 1898 with zoologist F ...
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Treponema Pallidum
''Treponema pallidum'', formerly known as ''Spirochaeta pallida'', is a Microaerophile, microaerophilic, Gram-negative bacteria, gram-negative, spirochaete bacterium with subspecies that cause the diseases syphilis, bejel (also known as endemic syphilis), and yaws. It is known to be transmitted only among humans and baboons. ''T. pallidum'' can enter the host through mucosal membranes or open lesions in the skin and is primarily spread through sexual contact. It is a helically coiled microorganism usually 6–15 μm long and 0.1–0.2 μm wide. ''T. pallidum'''s lack of both a Citric acid cycle, tricarboxylic acid cycle and processes for oxidative phosphorylation results in minimal metabolic activity. As a Chemoorganoheterotrophic, chemoorganoheterotroph, ''Treponema pallidum'' is an obligate parasite that acquires its glucose carbon source from its host. Glucose can be used not only as a primary carbon source but also in glycolytic mechanisms to generate ATP needed to power the ...
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Spirochaete
A spirochaete () or spirochete is a member of the phylum Spirochaetota (also called Spirochaetes ), which contains distinctive diderm (double-membrane) Gram-negative bacteria, most of which have long, helically coiled (corkscrew-shaped or spiraled, hence the name) cells. Spirochaetes are chemoheterotrophic in nature, with lengths between 3 and 500 μm and diameters around 0.09 to at least 3 μm. Spirochaetes are distinguished from other bacterial phyla by the location of their flagella, called endoflagella, or periplasmic flagella, which are sometimes called ''axial filaments''. Endoflagella are anchored at each end (pole) of the bacterium within the periplasmic space (between the inner and outer membranes) where they project backwards to extend the length of the cell. These cause a twisting motion which allows the spirochaete to move. When reproducing, a spirochaete will undergo asexual transverse binary fission. Most spirochaetes are free-living and anaero ...
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Frankfurt
Frankfurt am Main () is the most populous city in the States of Germany, German state of Hesse. Its 773,068 inhabitants as of 2022 make it the List of cities in Germany by population, fifth-most populous city in Germany. Located in the foreland of the Taunus on its namesake Main (river), Main, it forms a continuous conurbation with Offenbach am Main; Frankfurt Rhein-Main Regional Authority, its urban area has a population of over 2.7 million. The city is the heart of the larger Rhine-Main metropolitan region, which has a population of more than 5.8 million and is Germany's Metropolitan regions in Germany, second-largest metropolitan region after the Rhine-Ruhr metropolitan region, Rhine-Ruhr region and the List of EU metropolitan regions by GDP#2021 ranking of top four German metropolitan regions, fourth largest metropolitan region by GDP in the European Union (EU). Frankfurt is one of the ''de facto'' four main capitals of the European Union (alongside Brussels, Luxembourg Cit ...
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Hata Sahachiro
Hata may refer to: Places *Hata, Nagano, a former town in Nagano Prefecture, Japan *Hata District, Kōchi, a district in Kōchi Prefecture, Japan *Hata, India, a town and municipal council in Uttar Pradesh, India *Hata (Assembly constituency), a constituency of the Uttar Pradesh Legislative Assembly *Hata, a former village that is now the site of Ahta Indian Reserve No. 3 *Hata, Purvi Singhbhum, a village in Jharkhand, India Other uses *Hata (surname), a Japanese surname *Hata clan, a former immigrant clan to Japan See also *Hata Station (other), multiple railway stations in Japan *Hatamoto A was a high ranking samurai in the direct service of the Tokugawa shogunate of feudal Japan. While all three of the Shōgun, shogunates in History of Japan, Japanese history had official retainers, in the two preceding ones, they were referred ...
{{disambiguation, geo ...
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Portrait Of Paul Ehrlich And Sahachiro Hata Wellcome M0013258
A portrait is a painting, photograph, sculpture, or other artistic representation of a person, in which the face is always predominant. In arts, a portrait may be represented as half body and even full body. If the subject in full body better represents personality and mood, this type of presentation may be chosen. The intent is to display the likeness, personality, and even the mood of the person. For this reason, in photography a portrait is generally not a snapshot, but a composed image of a person in a still position. A portrait often shows a person looking directly at the painter or photographer, to most successfully engage the subject with the viewer, but portrait may be represented as a profile (from aside) and 3/4. History Prehistorical portraiture Plastered human skulls were reconstructed human skulls that were made in the ancient Levant between 9000 and 6000 BC in the Pre-Pottery Neolithic B period. They represent some of the oldest forms of art in the Middle East ...
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Yersinia Pestis
''Yersinia pestis'' (''Y. pestis''; formerly ''Pasteurella pestis'') is a Gram-negative bacteria, gram-negative, non-motile bacteria, non-motile, coccobacillus Bacteria, bacterium without Endospore, spores. It is related to pathogens ''Yersinia enterocolitica'', and ''Yersinia pseudotuberculosis'', from which it evolved. ''Yersinia pestis'' is responsible for the disease plague (disease), plague, which caused the Plague of Justinian and the Black Death, one of the deadliest pandemics in recorded history. Plague takes three main forms: Pneumonic plague, pneumonic, Septicemic plague, septicemic, and bubonic plague, bubonic. ''Y. pestis'' is a facultative anaerobic organism, facultative anaerobic Parasitism, parasitic bacterium that can infect humans primarily via its host the Oriental rat flea (''Xenopsylla cheopis''), but also through airborne transmission , aerosols and airborne droplets for its pneumonic form. As a parasite of its host, the rat flea, which is also a parasit ...
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