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Saccharopolyspora Spinosa
''Saccharopolyspora spinosa'' is a species of actinobacterium first isolated from soil in a rum still in an abandoned sugar mill on the Virgin Islands. It was discovered and described by researchers Mertz and Yao while collecting specimens to be screened for novel antibiotics. It develops aerial, pale, yellowish pink hyphae and bears long chains of spores encased in spiny spore sheaths. It can also reproduce by fragmentation in an aqueous environment. Its type strain is A83543.1 (= NRRL 18395). ''Saccharopolyspora spinosa'' is the source of a family of insecticidal compounds called spinosyns. They act as neurotoxins by activation of nicotinic acetylcholine receptors in insects. The insecticide Spinetoram is composed of two synthetic derivatives of spinosyns. See also *Spinosad Spinosad is an insecticide based on chemical compounds found in the bacterial species '' Saccharopolyspora spinosa''. The genus '' Saccharopolyspora'' was discovered in 1985 in isolates from crush ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Actinobacterium
The Actinomycetota (or Actinobacteria) are a diverse phylum of Gram-positive bacteria with high GC content. They can be terrestrial or aquatic. They are of great importance to land flora because of their contributions to soil systems. In soil they help to decompose the organic matter of dead organisms so the molecules can be taken up anew by plants. While this role is also played by fungi, Actinomycetota are much smaller and likely do not occupy the same ecological niche. In this role the colonies often grow extensive mycelia, as fungi do, and the name of an important order of the phylum, Actinomycetales (the actinomycetes), reflects that they were long believed to be fungi. Some soil actinomycetota (such as '' Frankia'') live symbiotically with the plants whose roots pervade the soil, fixing nitrogen for the plants in exchange for access to some of the plant's saccharides. Other species, such as many members of the genus ''Mycobacterium'', are important pathogens. Beyond th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virgin Islands
The Virgin Islands () are an archipelago between the Atlantic Ocean, North Atlantic Ocean and northeastern Caribbean Sea, geographically forming part of the Leeward Islands of the Lesser Antilles in the Caribbean, Caribbean islands or West Indies. Geology, Geologically separated from the Lesser Antilles by the Anegada Passage and from the Greater Antilles by the Mona Passage, Mona passage, all the islands except for Saint Croix lie on the same carbonate platform and Continental shelf, insular shelf, known as the Puerto Rico Bank, and same List of tectonic plates#Microplates, tectonic plate, known as the Puerto Rico–Virgin Islands microplate. Politically, the islands fall into three jurisdiction (area), jurisdictions: the easternmost British Overseas Territories, British overseas territory of the British Virgin Islands, Virgin Islands, informally referred to as the ''British Virgin Islands'', the central Territories of the United States, unincorporated American territory of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antibiotic
An antibiotic is a type of antimicrobial substance active against bacteria. It is the most important type of antibacterial agent for fighting pathogenic bacteria, bacterial infections, and antibiotic medications are widely used in the therapy, treatment and antibiotic prophylaxis, prevention of such infections. They may either bactericide, kill or bacteriostatic agent, inhibit the growth of bacteria. A limited number of antibiotics also possess antiprotozoal activity. Antibiotics are not effective against viruses such as the ones which cause the common cold or influenza. Drugs which inhibit growth of viruses are termed antiviral drugs or antivirals. Antibiotics are also not effective against fungi. Drugs which inhibit growth of fungi are called antifungal drugs. Sometimes, the term ''antibiotic''—literally "opposing life", from the Greek language, Greek roots ἀντι ''anti'', "against" and βίος ''bios'', "life"—is broadly used to refer to any substance used against ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hyphae
A hypha (; ) is a long, branching, filamentous structure of a fungus, oomycete, or actinobacterium. In most fungi, hyphae are the main mode of vegetative growth, and are collectively called a mycelium. Structure A hypha consists of one or more cells surrounded by a tubular cell wall. In most fungi, hyphae are divided into cells by internal cross-walls called "septa" (singular septum). Septa are usually perforated by pores large enough for ribosomes, mitochondria, and sometimes nuclei to flow between cells. The major structural polymer in fungal cell walls is typically chitin, in contrast to plants and oomycetes that have cellulosic cell walls. Some fungi have aseptate hyphae, meaning their hyphae are not partitioned by septa. Hyphae have an average diameter of 4–6 μm. Growth Hyphae grow at their tips. During tip growth, cell walls are extended by the external assembly and polymerization of cell wall components, and the internal production of new cell membran ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spore
In biology, a spore is a unit of sexual reproduction, sexual (in fungi) or asexual reproduction that may be adapted for biological dispersal, dispersal and for survival, often for extended periods of time, in unfavourable conditions. Spores form part of the Biological life cycle, life cycles of many plants, algae, fungus, fungi and protozoa. They were thought to have appeared as early as the mid-late Ordovician period as an adaptation of early land plants. Bacterial spores are not part of a sexual cycle, but are resistant structures used for survival under unfavourable conditions. Myxozoan spores release amoeboid infectious germs ("amoebulae") into their hosts for parasitic infection, but also reproduce within the hosts through the pairing of two nuclei within the plasmodium, which develops from the amoebula. In plants, spores are usually haploid and unicellular and are produced by meiosis in the sporangium of a diploid sporophyte. In some rare cases, a diploid spore is also p ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fragmentation (reproduction)
Fragmentation in multicellular or colonial organisms is a form of asexual reproduction or cloning, where an organism is split into fragments upon maturation and the split part becomes the new individual. The organism may develop specific organs or zones to shed or be easily broken off. If the splitting occurs without the prior preparation of the organism, both fragments must be able to regeneration (biology), regenerate the complete organism for it to function as reproduction. Fragmentation as a method of reproduction is seen in organisms such as spirogyra, filamentous cyanobacteria, Mold (fungus), molds, lichens, sponges, acoelomorpha, acoel flatworms, some annelid worms and sea stars. Fragmentation in various organisms Molds, yeasts and mushrooms, all of which are part of the Fungi kingdom (biology), kingdom, produce tiny filaments called hyphae. These hyphae obtain food and nutrients from the body of other organisms to grow and fertilize. Then a piece of hyphae breaks off an ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinosad
Spinosad is an insecticide based on chemical compounds found in the bacterial species '' Saccharopolyspora spinosa''. The genus '' Saccharopolyspora'' was discovered in 1985 in isolates from crushed sugarcane. The bacteria produce yellowish-pink aerial hyphae, with bead-like chains of spores enclosed in a characteristic hairy sheath. This genus is defined as aerobic, Gram-positive, nonacid-fast actinomycetes with fragmenting substrate mycelium. ''S. spinosa'' was isolated from soil collected inside a nonoperational sugar mill rum still in the Virgin Islands. Spinosad is a mixture of chemical compounds in the spinosyn family that has a generalized structure consisting of a unique tetracyclic ring system attached to an amino sugar (D-forosamine) and a neutral sugar (tri-''Ο''-methyl-L-rhamnose). Spinosad is relatively nonpolar and not easily dissolved in water. Spinosad is a novel mode-of-action insecticide derived from a family of natural products obtained by fermentation of ' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotoxin
Neurotoxins are toxins that are destructive to nervous tissue, nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological insult (medical), insultsSpencer 2000 that can adversely affect function in both developing and mature nervous tissue.Olney 2002 The term can also be used to classify endogenous compounds, which, when abnormally contacted, can prove neurologically toxic. Though neurotoxins are often neurologically destructive, their ability to specifically target neural components is important in the study of nervous systems. Common examples of neurotoxins include lead, ethanol (drinking alcohol), glutamate,Choi 1987 nitric oxide, botulinum toxin (e.g. Botox), tetanus toxin,Simpson 1986 and tetrodotoxin. Some substances such as nitric oxide and glutamate are in fact essential for proper function of the body and only exert neurotoxic effects at excessive concentrations. Neurotoxins inhibit neuron control over ion concentrations ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nicotinic Acetylcholine Receptor
Nicotinic acetylcholine receptors, or nAChRs, are Receptor (biochemistry), receptor polypeptides that respond to the neurotransmitter acetylcholine. Nicotinic receptors also respond to drugs such as the agonist nicotine. They are found in the central and peripheral nervous system, muscle, and many other tissues of many organisms. At the neuromuscular junction they are the primary receptor in muscle for motor nerve-muscle communication that controls muscle contraction. In the peripheral nervous system: (1) they transmit outgoing signals from the presynaptic to the postsynaptic cells within the Sympathetic nervous system, sympathetic and parasympathetic nervous system, and (2) they are the receptors found on skeletal muscle that receive acetylcholine released to signal for muscular contraction. In the immune system, nAChRs regulate inflammatory processes and signal through distinct intracellular pathways. In insects, the cholinergic system is limited to the central nervous system. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spinetoram
Spinetoram (marketed as Cheristin in its topical veterinary dosage-form) is an insecticidal mixture of two active neurotoxic constituents of '' Saccharopolyspora spinosa''. It is used to control pest insects in stored grain and on domestic cats. See also *Spinosad Spinosad is an insecticide based on chemical compounds found in the bacterial species '' Saccharopolyspora spinosa''. The genus '' Saccharopolyspora'' was discovered in 1985 in isolates from crushed sugarcane. The bacteria produce yellowish-p ... References {{reflist Insecticides Dimethylamino compounds Methoxy compounds Ethoxy compounds Heterocyclic compounds with 4 rings Lactones ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pseudonocardineae
The Pseudonocardiaceae are a family of bacteria in the order Actinomycetales and the only member of the suborder Pseudonocardineae. Genomics The species within the family Pseudonocardiaceae form a distinct clade in phylogenetic trees based on concatenated protein sequences. Additionally, ''Nakamurella multipartite'', currently part of the order Frankiales, also formed a clade with the Pseudonocardiaceae species in 100% of the Bootstrapping (statistics), bootstrap replications of the phylogenetic trees. A conserved signature indels, conserved signature indel has been identified which is found in ''N. multipartite'' and all but one of the Pseudonocardiaceae species. This one-amino-acid insertion in UMP kinase serves to both provide a Genetic marker, molecular marker for nearly all of the Pseudonocardiaceae and suggests ''N. multipartite'' is closely related to this group. Some evidence also suggests the orders Pseudonocardiales and Corynebacteriales are closely related. Several cons ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
