Rush Religious Orders Study
The Religious Orders Study conducted at the Rush Alzheimer's Disease Center at Rush University in Chicago is a research project begun in 1994 exploring the effects of aging on the brain.David Eagleman, ''The Brain'', Pantheon Books, 2015, p. 28-29 More than 1,500 nuns, priests, and other religious professionals are participating across the United States. The study is finding that cognitive exercise including social activities and learning new skills has a protective effect on brain health and the onset of dementia, while negative psychological factors like anxiety and clinical depression are correlated with cognitive decline. The Religious Orders Study follows the earlier Nun Study. Initial funding was provided by the National Institute on Aging The National Institute on Aging (NIA) is a division of the U.S. National Institutes of Health (NIH), located in Bethesda, Maryland. The NIA itself is headquartered in Baltimore, Maryland. The NIA leads a broad scientific effort to understan ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rush Alzheimer's Disease Center
The Rush Alzheimer's Disease Center (RADC) is an independent research center located in the Medical College of Rush University Medical Center. The Rush Alzheimer's Disease Center is one of the Alzheimer's Disease Research Centers in the U.S. designated and funded by the National Institute on Aging. The RADC was founded by Dr. James Schoenberger in 1985. Dr. David A Bennett, a neurologist, became the third RADC Director in 1998 following Dr. Jacob H Fox. From 2001-2022, Dr. Bennett also led Alzheimer's Disease Research Center (ADRC) funded by the NIA following Dr. Denis Evans who lead the ADRC from 1991-2001; this grant is now led by neuropathologist and neurologist Dr. Julie A Schneider. The RADC is a leader in research into the causes, treatments, and prevention of Alzheimer's disease and related disorders. One of its earliest research projects was the Religious Orders Study. The Religious Orders Study, led by Dr. Bennett, was initially funded by the National Institute on ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Rush University
Rush University is a private research university in Chicago, Illinois. The university, founded in 1972, is the academic arm of Rush University Medical Center. Rush University comprises: * Rush Medical College * Rush University College of Nursing * Rush University College of Health Sciences * The Graduate College of Rush University Rush encompasses a 664-bed hospital serving adults and children, the 61-bed Johnston R. Bowman Health Center and Rush University. The campus occupies an site on Chicago's Near West Side, in the Illinois Medical District, which also includes its teaching hospital, Rush University Medical Center. History Founding of Rush University Rush University Medical Center dates back to March 2, 1837, when Rush Medical College received its charter. Daniel Brainard, MD, founded Rush Medical College in March 1837, two days before Chicago was chartered as a city. It took seven years from the granting of the charter before Rush Medical College opened officially o ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Chicago
(''City in a Garden''); I Will , image_map = , map_caption = Interactive Map of Chicago , coordinates = , coordinates_footnotes = , subdivision_type = List of sovereign states, Country , subdivision_name = United States , subdivision_type1 = U.S. state, State , subdivision_type2 = List of counties in Illinois, Counties , subdivision_name1 = Illinois , subdivision_name2 = Cook County, Illinois, Cook and DuPage County, Illinois, DuPage , established_title = Settled , established_date = , established_title2 = Municipal corporation, Incorporated (city) , established_date2 = , founder = Jean Baptiste Point du Sable , government_type = Mayor–council government, Mayor–council , governing_body = Chicago City Council , leader_title = Mayor of Chicago, Mayor , leader_name = Lori Lightfo ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Brain
The brain is an organ that serves as the center of the nervous system in all vertebrate and most invertebrate animals. It consists of nervous tissue and is typically located in the head ( cephalization), usually near organs for special senses such as vision, hearing and olfaction. Being the most specialized organ, it is responsible for receiving information from the sensory nervous system, processing those information (thought, cognition, and intelligence) and the coordination of motor control (muscle activity and endocrine system). While invertebrate brains arise from paired segmental ganglia (each of which is only responsible for the respective body segment) of the ventral nerve cord, vertebrate brains develop axially from the midline dorsal nerve cord as a vesicular enlargement at the rostral end of the neural tube, with centralized control over all body segments. All vertebrate brains can be embryonically divided into three parts: the forebrain (prosencep ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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David Eagleman
David Eagleman (born April 25, 1971) is an American neuroscientist, author, and science communicator. He teaches neuroscience at Stanford University and is CEO and co-founder of Neosensory, a company that develops devices for sensory substitution. He also directs the non-profit Center for Science and Law, which seeks to align the legal system with modern neuroscience and is Chief Science Officer and co-founder of BrainCheck, a digital cognitive health platform used in medical practices and health systems. He is known for his work on brain plasticity,David Eagleman TED talk March 18, 2015. , [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Dementia
Dementia is a disorder which manifests as a set of related symptoms, which usually surfaces when the brain is damaged by injury or disease. The symptoms involve progressive impairments in memory, thinking, and behavior, which negatively affects a person's ability to function and carry out everyday activities. Aside from memory impairment and a disruption in thought patterns, the most common symptoms include emotional problems, difficulties with language, and decreased motivation. The symptoms may be described as occurring in a continuum over several stages. Consciousness is not affected. Dementia ultimately has a significant effect on the individual, caregivers, and on social relationships in general. A diagnosis of dementia requires the observation of a change from a person's usual mental functioning, and a greater cognitive decline than what is caused by normal aging. Several diseases and injuries to the brain, such as a stroke, can give rise to dementia. However, t ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Anxiety
Anxiety is an emotion which is characterized by an unpleasant state of inner turmoil Turmoil may refer to: * ''Turmoil'' (1984 video game), a 1984 video game released by Bug-Byte * ''Turmoil'' (2016 video game), a 2016 indie oil tycoon video game * Turmoil (''Transformers''), a fictional character * Turmoil, a character in the ... and includes feelings of dread over Anticipation, anticipated events. Anxiety is different than fear in that the former is defined as the anticipation of a future threat whereas the latter is defined as the emotional response to a real threat. It is often accompanied by nervous behavior such as pacing back and forth, Somatic anxiety, somatic complaints, and Rumination (psychology), rumination. Anxiety is a feeling of uneasiness and worry, usually generalized and unfocused as an overreaction to a situation that is only subjectively seen as menacing. It is often accompanied by muscular tension, restlessness, Fatigue (medical), fatigue, inability to ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Clinical Depression
Major depressive disorder (MDD), also known as clinical depression, is a mental disorder characterized by at least two weeks of pervasive low mood, low self-esteem, and loss of interest or pleasure in normally enjoyable activities. Introduced by a group of US clinicians in the mid-1970s, the term was adopted by the American Psychiatric Association for this symptom cluster under mood disorders in the 1980 version of the '' Diagnostic and Statistical Manual of Mental Disorders'' (DSM-III), and has become widely used since. The diagnosis of major depressive disorder is based on the person's reported experiences, behavior reported by relatives or friends, and a mental status examination. There is no laboratory test for the disorder, but testing may be done to rule out physical conditions that can cause similar symptoms. The most common time of onset is in a person's 20s, with females affected about twice as often as males. The course of the disorder varies widely, from one e ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Nun Study
The Nun Study of Aging and Alzheimer's Disease is a continuing longitudinal study, begun in 1986, to examine the onset of Alzheimer's disease. David Snowdon, an Epidemiologist and the founding Nun Study investigator, started the Nun Study at the University of Minnesota, later transferring the study to the University of Kentucky in 1990. In 2008, with Snowdon's retirement, the study returned to the University of Minnesota. The Nun Study was very briefly moved from the University of Minnesota to Northwestern University in 2021 under the directorship of Dr. Margaret Flanagan. The Nun Study is currently housed at the University of Texas Health San Antonio in the Bigg's Institute for Alzheimer's and Neurodegenerative diseases under the continued directorship of Neuropathologist, Dr. Margaret Flanagan. The Sisters' autobiographies written just before they took their vows (ages 19–21) revealed that positivity was closely related to longevity and idea density, which is related to convers ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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National Institute On Aging
The National Institute on Aging (NIA) is a division of the U.S. National Institutes of Health (NIH), located in Bethesda, Maryland. The NIA itself is headquartered in Baltimore, Maryland. The NIA leads a broad scientific effort to understand the nature of aging and to extend the healthy, active years of life. In 1974, under Public Law 93-296, Congress granted authority to form NIA to provide leadership in aging research, training, health information dissemination, and other programs relevant to aging and older people. In January 2011, President Obama signed into law the National Alzheimer’s Project Act, designating the NIA as the primary federal agency on Alzheimer's disease research. NIA is led by Director, Richard J. Hodes, M.D, and Acting Deputy Director Melinda Kelley, M.D. Mission NIA's mission is to improve the health and well-being of older Americans through research, and specifically to: *Support and conduct high-quality research on: **Aging processes **Age-related d ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Neuroscience Projects
Neuroscience is the scientific study of the nervous system (the brain, spinal cord, and peripheral nervous system), its functions and disorders. It is a multidisciplinary science that combines physiology, anatomy, molecular biology, developmental biology, cytology, psychology, physics, computer science, chemistry, medicine, statistics, and mathematical modeling to understand the fundamental and emergent properties of neurons, glia and neural circuits. The understanding of the biological basis of learning, memory, behavior, perception, and consciousness has been described by Eric Kandel as the "epic challenge" of the biological sciences. The scope of neuroscience has broadened over time to include different approaches used to study the nervous system at different scales. The techniques used by neuroscientists have expanded enormously, from molecular and cellular studies of individual neurons to imaging of sensory, motor and cognitive tasks in the brain. History The earlie ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Alzheimer's Disease
Alzheimer's disease (AD) is a neurodegeneration, neurodegenerative disease that usually starts slowly and progressively worsens. It is the cause of 60–70% of cases of dementia. The most common early symptom is difficulty in short-term memory, remembering recent events. As the disease advances, symptoms can include primary progressive aphasia, problems with language, Orientation (mental), disorientation (including easily getting lost), mood swings, loss of motivation, self-neglect, and challenging behaviour, behavioral issues. As a person's condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the typical life expectancy following diagnosis is three to nine years. The cause of Alzheimer's disease is poorly understood. There are many environmental and genetic risk factors associated with its development. The strongest genetic risk factor is from an alle ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |