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Ruggero Ceppellini
Ruggero Ceppellini (1917 in Milan – 1988) was a leading Italian geneticist. Ceppellini made several important contributions in the field of immunogenetics, and understanding of the human leukocyte antigen (HLA). During service as a sergeant in World War II, Ceppellini was captured by the British and as a prisoner of war in Palestine, was a medical orderly under Chaim Sheba. After the war he finished his medical training and decided to specialize in genetics; Luca Cavalli-Sforza influenced his decision and obtained a place for him at the University of Milan ''Istituto Sieroterapico Milanese''.W. F. Bodmer"In memoriam: Ruggiero Ceppellini, 1917 – 1988" ''Immunogenetics'' 29 (1989) 145–47 (pdf) Ceppellini trained at the Lister Institute in London, then was visiting investigator at the University of Columbia Institute for the Study of Human Variation.Paul Lawrence Farber, Hamilton Cravens ''Race and Science: Scientific Challenges to Racism in Modern America'' 2009 Page ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Milan
Milan ( , , ; ) is a city in northern Italy, regional capital of Lombardy, the largest city in Italy by urban area and the List of cities in Italy, second-most-populous city proper in Italy after Rome. The city proper has a population of nearly 1.4 million, while its Metropolitan City of Milan, metropolitan city has 3.2 million residents. Within Europe, Milan is the fourth-most-populous List of urban areas in the European Union, urban area of the EU with 6.17 million inhabitants. According to national sources, the population within the wider Milan metropolitan area (also known as Greater Milan) is estimated between 7.5 million and 8.2 million, making it by far the List of metropolitan areas of Italy, largest metropolitan area in Italy and List of metropolitan areas in Europe, one of the largest in the EU.* * * * Milan is the economic capital of Italy, one of the economic capitals of Europe and a global centre for business, fashion and finance. Milan is reco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Immunogenetics
Immunogenetics or immungenetics is the branch of Medical Immunology and Medical Genetics that explores the relationship between the immune system and genetics. Autoimmune diseases, such as type 1 diabetes, are complex genetic traits which result from defects in the immune system. Identification of genes defining the immune defects may identify new target genes for therapeutic approaches. Alternatively, genetic variations can also help to define the immunological pathway leading to disease. Origin The term immunogenetics is based on the two words immunology and genetics, and is defined as "a sub discipline of genetics which deals with the genetic basis of the immune response (immunity)" according to MeSH. Genetics (based on Greek γενεά ''geneá'' "descent" and γένεσις ''génesis'' "origin") is the science researching the transfer of characteristics from one generation to the next. The genes of an organism (strands of DNA) and the transfer of genes from the parent to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Human Leukocyte Antigen
The human leukocyte antigen (HLA) system is a complex of genes on chromosome 6 in humans that encode cell-surface proteins responsible for regulation of the immune system. The HLA system is also known as the human version of the major histocompatibility complex (MHC) found in many animals. Mutations in HLA genes may be linked to autoimmune diseases such as type I diabetes, and celiac disease. The HLA gene complex resides on a 3 Mbp stretch within chromosome 6, p-arm at 21.3. HLA genes are highly polymorphic, which means that they have many different alleles, allowing them to fine-tune the adaptive immune system. The proteins encoded by certain genes are also known as '' antigens'', as a result of their historic discovery as factors in organ transplants. HLAs corresponding to MHC class I ( A, B, and C), all of which are the HLA Class1 group, present peptides from inside the cell. For example, if the cell is infected by a virus, the HLA system brings fragments of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
World War II
World War II or the Second World War (1 September 1939 – 2 September 1945) was a World war, global conflict between two coalitions: the Allies of World War II, Allies and the Axis powers. World War II by country, Nearly all of the world's countries participated, with many nations mobilising all resources in pursuit of total war. Tanks in World War II, Tanks and Air warfare of World War II, aircraft played major roles, enabling the strategic bombing of cities and delivery of the Atomic bombings of Hiroshima and Nagasaki, first and only nuclear weapons ever used in war. World War II is the List of wars by death toll, deadliest conflict in history, causing World War II casualties, the death of 70 to 85 million people, more than half of whom were civilians. Millions died in genocides, including the Holocaust, and by massacres, starvation, and disease. After the Allied victory, Allied-occupied Germany, Germany, Allied-occupied Austria, Austria, Occupation of Japan, Japan, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Prisoner Of War
A prisoner of war (POW) is a person held captive by a belligerent power during or immediately after an armed conflict. The earliest recorded usage of the phrase "prisoner of war" dates back to 1610. Belligerents hold prisoners of war for a range of legitimate and illegitimate reasons. These may include isolating them from enemy combatants still in the field (releasing and Repatriation, repatriating them in an orderly manner after hostilities), demonstrating military victory, punishment, prosecution of war crimes, labour exploitation, recruiting or even conscripting them as combatants, extracting collecting military and political intelligence, and political or religious indoctrination. Ancient times For much of history, prisoners of war would often be slaughtered or enslaved. Early Roman gladiators could be prisoners of war, categorised according to their ethnic roots as Samnites, Thracians, and Gauls (''Galli''). Homer's ''Iliad'' describes Trojan and Greek soldiers offeri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Palestine (region)
The region of Palestine, also known as historic Palestine, is a geographical area in West Asia. It includes the modern states of Israel and Palestine, as well as parts of northwestern Jordan in some definitions. Other names for the region include Canaan, the Promised Land, the Land of Israel, or the Holy Land. The earliest written record Timeline of the name Palestine, referring to Palestine as a geographical region is in the ''Histories (Herodotus), Histories'' of Herodotus in the 5th century BCE, which calls the area ''Palaistine'', referring to the territory previously held by Philistia, a state that existed in that area from the 12th to the 7th century BCE. The Roman Empire conquered the region and in 6 CE established the province known as Judaea (Roman province), Judaea. In the aftermath of the Bar Kokhba revolt (132–136 CE), the province was renamed Syria Palaestina. In 390, during the Byzantine period, the region was split into the provinces of Palaestina Prima, Pal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chaim Sheba
Chaim Sheba (; born 1908, died 10 July 1971) was an Israeli physician and the founder of Sheba Medical Center. Biography Chaim Scheiber (later Sheba) was born in Frasin, near Gurahumora, Bukovina, then in Austria-Hungary (now Suceava County, Romania), to the well known Scheiber Hasidic family, a descendant of the Hasidic court of Ruzhin. As a young child he studied in heder, a school for religious studies only. He transferred from there to the 8th grade in a secular school. Influenced by his grandfather, he began medical studies in Cernăuți and completed such studies in Vienna in December 1932. In the beginning of 1933, Sheba immigrated to Mandate Palestine. Sheba died in 1971 of a heart attack. Medical career Until 1936, Sheba served as rural doctor and later in Beilinson Hospital. In 1942, he joined the Jewish Brigade as a doctor, joining the Haganah in 1947. From 1948 to 1950, he commanded the Medical Corps of the Israel Defense Forces (IDF), and became Director Gene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Luca Cavalli-Sforza
Luigi Luca Cavalli-Sforza (; 25 January 1922 – 31 August 2018) was an Italian geneticist. He was a population geneticist who taught at the University of Parma, the University of Pavia and then at Stanford University. Works Schooling and positions Cavalli-Sforza entered Ghislieri College in Pavia in 1939 and he received his M.D. from the University of Pavia in 1944. In 1949, he was appointed to a research post at the Department of Genetics, Cambridge University by the statistician and evolutionary biologist Ronald A. Fisher in the field of ''E. coli'' genetics. In 1950, he left the University of Cambridge to teach in northern Italy (Parma, and Pavia) before taking up a professorship at Stanford in 1970. He remained at Stanford until he retired in 1992. In 1999 he won the Balzan Prize for the Science of human origins. He has been a member of the Pontifical Academy of Sciences since 1994. In 1992 he was elected Foreign Member of the Royal Society of London. He was awarded the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Milan
The University of Milan (; ), officially abbreviated as UNIMI, or colloquially referred to as La Statale ("the State [University]"), is a public university, public research university in Milan, Italy. It is one of the largest universities in Europe, with about 60,000 students, and a permanent teaching and research staff of about 2,000. The University of Milan has ten schools and offers 140 undergraduate and graduate degree programmes, 32 Doctoral Schools and 65+ Specialization Schools. The University's research and teaching activities have grown over the years and have received important international recognitions. The University is the only Italian member of the League of European Research Universities (LERU), a group of twenty-one research-intensive European universities. The university has been frequented by many University of Milan#Notable alumni, notable alumni, including Enrico Bombieri (Fields medalist, 1974), Riccardo Giacconi (Nobel laureate in Physics, 2002), Marco Be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lister Institute
The Lister Institute of Preventive Medicine, informally known as the Lister Institute, was established as a research institute (the British Institute of Preventive Medicine) in 1891, with bacteriologist Marc Armand Ruffer as its first director, using a grant of £250,000 from Edward Cecil Guinness of the Guinness family. It had premises in Chelsea in London, Sudbury in Suffolk, and Elstree in Hertfordshire, England. It was the first medical research charity in the United Kingdom. It was renamed the Jenner Institute (after Edward Jenner, the pioneer of smallpox vaccine) in 1898 and then, in 1903, as the Lister Institute in honour of the great surgeon and medical pioneer, Dr Joseph Lister. In 1905, the institute became a school of the University of London. History The early history of the Lister Institute could best be described as having a chequered history. It began with French chemist and microbiologist Louis Pasteur in 1880 when two rabid dogs were brought to Pasteur fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Columbia
Columbia University in the City of New York, commonly referred to as Columbia University, is a private Ivy League research university in New York City. Established in 1754 as King's College on the grounds of Trinity Church in Manhattan, it is the oldest institution of higher education in New York and the fifth- oldest in the United States. Columbia was established as a colonial college by royal charter under George II of Great Britain. It was renamed Columbia College in 1784 following the American Revolution, and in 1787 was placed under a private board of trustees headed by former students Alexander Hamilton and John Jay. In 1896, the campus was moved to its current location in Morningside Heights and renamed Columbia University. Columbia is organized into twenty schools, including four undergraduate schools and 16 graduate schools. The university's research efforts include the Lamont–Doherty Earth Observatory, the Goddard Institute for Space Studies, and accelerator ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Turin
The University of Turin (Italian language, Italian: ''Università degli Studi di Torino'', UNITO) is a public university, public research university in the city of Turin, in the Piedmont (Italy), Piedmont region of Italy. It is one of the List of oldest universities in continuous operation, oldest universities in Europe and continues to play an important role in research and training. History Overview The University of Turin was founded as a ''studium'' in 1404, under the initiative of Prince Louis of Piedmont, Ludovico di Savoia. From 1427 to 1436 the seat of the university was transferred to Chieri and Savigliano. It was closed in 1536 following the invasion of the Savoy lands by France, and reestablished by Duke Emmanuel Philibert, Duke of Savoy, Emmanuel Philibert thirty years later. It started to gain its modern shape following the model of the University of Bologna, although significant development did not occur until the reforms made by Victor Amadeus II of Sardinia, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
