|
Rubella Virus
Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy. Rubella virus, scientific name ''Rubivirus rubellae'', is a member of the genus '' Rubivirus'' and belongs to the family of ''Matonaviridae'', whose members commonly have a genome of single-stranded RNA of positive polarity which is enclosed by an icosahedral capsid. the molecular basis for the causation of congenital rubella syndrome was not yet completely clear, but ''in vitro'' studies with cell lines showed that rubella virus has an apoptotic effect on certain cell types. There is evidence for a p53-dependent mechanism. Taxonomy Rubella virus (''Rubivirus rubellae'') is assigned to the ''Rubivirus'' genus. ''Matonaviridae'' family Until 2018, Rubiviruses were classified as part of the family ''Togaviridae'', but have since been chan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transmission Electron Micrograph
Transmission electron microscopy (TEM) is a microscopy technique in which a beam of electrons is transmitted through a specimen to form an image. The specimen is most often an ultrathin section less than 100 nm thick or a suspension on a grid. An image is formed from the interaction of the electrons with the sample as the beam is transmitted through the specimen. The image is then magnified and Focus (optics), focused onto an imaging device, such as a fluorescent screen, a layer of photographic film, or a Detectors for transmission electron microscopy, detector such as a scintillator attached to a charge-coupled device or a direct electron detector. Transmission electron microscopes are capable of imaging at a significantly higher Optical resolution, resolution than Optical microscope, light microscopes, owing to the smaller de Broglie wavelength of electrons. This enables the instrument to capture fine detail—even as small as a single column of atoms, which is thousands o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Committee On The Taxonomy Of Viruses
The International Committee on Taxonomy of Viruses (ICTV) authorizes and organizes the taxonomic classification of and the nomenclature for viruses. The ICTV develops a universal taxonomic scheme for viruses, and thus has the means to appropriately describe, name, and classify every virus taxon. The members of the International Committee on Taxonomy of Viruses are considered expert virologists. The ICTV was formed from and is governed by the Virology Division of the International Union of Microbiological Societies. Detailed work, such as identifying new taxa and delimiting the boundaries of species, genera, families, etc. typically is performed by study groups of experts in the families. History The International Committee on Nomenclature of Viruses (ICNV) was established in 1966, at the International Congress for Microbiology in Moscow, to standardize the naming of virus taxa. The ICVN published its first report in 1971. For viruses infecting vertebrates, the first report incl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Envelope
A viral envelope is the outermost layer of many types of viruses. It protects the genetic material in their life cycle when traveling between host cells. Not all viruses have envelopes. A viral envelope protein or E protein is a protein in the envelope, which may be acquired by the capsid from an infected host cell. Host cell infection process Numerous human pathogenic viruses in circulation are encased in lipid bilayers, and they infect their target cells by causing the viral envelope and cell membrane to fuse. Although there are effective vaccines against some of these viruses, there is no preventative or curative medicine for the majority of them. In most cases, the known vaccines operate by inducing antibodies that prevent the pathogen from entering cells. This happens in the case of enveloped viruses when the antibodies bind to the viral envelope proteins. The membrane fusion event that triggers viral entrance is caused by the viral membrane fusion protein. Many envelo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Virion
A virion (plural, ''viria'' or ''virions'') is an inert virus particle capable of invading a Cell (biology), cell. Upon entering the cell, the virion disassembles and the genetic material from the virus takes control of the cell infrastructure, thus enabling the virus to Replication (virus), replicate. The genetic material (''Viral core, core'', either DNA or RNA, along with occasionally present virus core protein) inside the virion is usually enclosed in a protection shell, known as the capsid. While the terms "virus" and "virion" are occasionally confused, recently "virion" is used solely to describe the virus structure outside of cells, while the terms "virus/viral" are broader and also include biological properties such as the infectivity of a virion. Components A virion consists of one or more nucleic acid genome molecules (single-stranded or double-stranded RNA or DNA) and coatings (a capsid and possibly a viral envelope). The virion may contain other proteins (for examp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alphatetraviridae
''Alphatetraviridae'' is a family of viruses. Moths and butterflies serve as natural hosts. There are two genera in the family. Infection outcome varies from unapparent to lethal. Taxonomy The following genera are assigned to the family: *'' Betatetravirus'' *'' Omegatetravirus'' Structure Viruses in ''Alphatetraviridae'' are non-enveloped, with icosahedral geometries, and T=4 symmetry. The diameter is around 40 nm. Genomes are linear and non-segmented, bipartite, around 6.5kb in length. Life cycle Viral replication is cytoplasmic. Entry into the host cell is achieved by penetration into the host cell. Replication follows the positive stranded RNA virus replication model. Positive stranded rna virus transcription is the method of transcription. Translation takes place by leaky scanning, and ribosomal skipping. Moths and butterflies serve as the natural host. Transmission routes are oral. References External links Viralzone: AlphatetraviridaeICTV {{Taxonbar, from ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hepeviridae
''Hepeviridae'' is a family of viruses. Human, pig, wild boar, sheep, cow, camel, monkey, some rodents, bats and chickens serve as natural hosts. There are two subfamilies with five genera in the family. Diseases associated with this family include: hepatitis; high mortality rate during pregnancy; and avian hepatitis E virus is the cause of hepatitis-splenomegaly (HS) syndrome among chickens. Taxonomy The following subfamilies and genera are assigned to the family (-''virinae'' denotes subfamily and -''viridae'' denotes family): * '' Orthohepevirinae'' ** '' Avihepevirus'' ** '' Chirohepevirus'' ** '' Paslahepevirus'' ** '' Rocahepevirus'' * '' Parahepevirinae'' ** '' Piscihepevirus'' Structure Viruses in the family ''Hepeviridae'' are non-enveloped, with icosahedral and spherical geometries, and T=1 symmetry. The diameter is around 32-34 nm. Genomes are linear and non-segmented, around 7.2kb in length. The genome has three open reading frames. Evolution This has been stu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Benyviridae
''Benyvirus'' is a genus of virus A virus is a submicroscopic infectious agent that replicates only inside the living Cell (biology), cells of an organism. Viruses infect all life forms, from animals and plants to microorganisms, including bacteria and archaea. Viruses are ...es, in the family ''Benyviridae''. Plants serve as natural hosts. There are four species in this genus. Diseases associated with this genus include: BNYVV: rhizomania. Taxonomy The genus contains the following species, listed with their scientific name and common name: * ''Benyvirus arctii'', Burdock mottle virus * ''Benyvirus necrobetae'', Beet necrotic yellow vein virus * ''Benyvirus oryzae'', Rice stripe necrosis virus, isolates of which are known as RSNV; a rod-shaped virus containing just six open reading frames in its genome. A pathogen of rice plants, it may cause chlorosis, necrosis, and malformation. * ''Benyvirus solibetae'', Beet soil-borne mosaic virus Structure Viruses in the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phylogeny
A phylogenetic tree or phylogeny is a graphical representation which shows the evolutionary history between a set of species or Taxon, taxa during a specific time.Felsenstein J. (2004). ''Inferring Phylogenies'' Sinauer Associates: Sunderland, MA. In other words, it is a branching diagram or a tree (graph theory), tree showing the evolutionary relationships among various biological species or other entities based upon similarities and differences in their physical or genetic characteristics. In evolutionary biology, all life on Earth is theoretically part of a single phylogenetic tree, indicating common ancestry. Phylogenetics is the study of phylogenetic trees. The main challenge is to find a phylogenetic tree representing optimal evolutionary ancestry between a set of species or taxa. computational phylogenetics, Computational phylogenetics (also phylogeny inference) focuses on the algorithms involved in finding optimal phylogenetic tree in the phylogenetic landscape. Phylogene ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nucleocapsid
A capsid is the protein shell of a virus, enclosing its genetic material. It consists of several oligomeric (repeating) structural subunits made of protein called protomers. The observable 3-dimensional morphological subunits, which may or may not correspond to individual proteins, are called capsomeres. The proteins making up the capsid are called capsid proteins or viral coat proteins (VCP). The virus genomic component inside the capsid, along with occasionally present virus core protein, is called the virus core. The capsid and core together are referred to as a nucleocapsid (cf. also virion). Capsids are broadly classified according to their structure. The majority of the viruses have capsids with either helical or icosahedral structure. Some viruses, such as bacteriophages, have developed more complicated structures due to constraints of elasticity and electrostatics. The icosahedral shape, which has 20 equilateral triangular faces, approximates a sphere, while the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Icosahedral
In geometry, an icosahedron ( or ) is a polyhedron with 20 faces. The name comes . The plural can be either "icosahedra" () or "icosahedrons". There are infinitely many non- similar shapes of icosahedra, some of them being more symmetrical than others. The best known is the (convex, non- stellated) regular icosahedron—one of the Platonic solids—whose faces are 20 equilateral triangles. Regular icosahedra There are two objects, one convex and one nonconvex, that can both be called regular icosahedra. Each has 30 edges and 20 equilateral triangle faces with five meeting at each of its twelve vertices. Both have icosahedral symmetry. The term "regular icosahedron" generally refers to the convex variety, while the nonconvex form is called a ''great icosahedron''. Convex regular icosahedron The convex regular icosahedron is usually referred to simply as the ''regular icosahedron'', one of the five regular Platonic solids, and is represented by its Schläfli symbol , containi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rustrela Virus
Rustrela virus, scientific name ''Rubivirus strelense'', is a species of virus in the genus '' Rubivirus''. History Scientists discovered Rustrela in acutely encephalitic placental and marsupial mammals – a donkey, a capybara, and a wallaby – in a zoo in Germany, and in wild yellow-necked field mice ('' Apodemus flavicollis'') in and around the zoo. – See also article correction: The virus can jump between species and interestingly infects both placental and marsupial animals. Structure The Rustrela virus has the same genomic structure as the Rubella virus Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the respiratory route, and is the main cause of congenital rubella syndrome when infection occurs during the first weeks of pregnancy. Rube .... Rustrela has a few amino acid differences in the protein which binds to host cells. There are four putative B cell epitopes in the fusion (E1 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ruhugu Virus
The Ruhugu virus, scientifically known as ''Rubivirus ruteetense'', is a type of virus that falls under the Rubivirus genus. It was first identified in 2019 within unaffected bats from Uganda. This virus is classified within the Matonaviridae family and consists of a single-stranded RNA with a positive polarity. It is encapsulated by an icosahedral capsid. Discovery and habitat Before the onset of the COVID-19 pandemic, the Ruhugu virus was detected in disease-free Cyclops roundleaf bats residing in Kibale National Park, Uganda. This discovery was made during a search for coronaviruses present in bat populations. Etymology Ruhugu virus was named after the Ruteete region of Uganda and the word in the local Tooro language, which describes "the flapping of bat wings in the hollow of a tree: obuhuguhugu" Structure Ruhugu virus is closely related to Rubella virus Rubella virus (RuV) is the pathogenic agent of the disease rubella, transmitted only between humans via the re ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
