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Rs1799913
In genetics, rs1799913, also called A779C, is a gene variation—a single nucleotide polymorphism (SNP)— in the TPH1 gene. It is located in intron 7. The SNP association with schizophrenia has been examined in several studies, though as of 2007 with no definitive conclusion. One study has found that the SNP may be associated with heroin addiction. Other study relate it to figural and numeric creativity. A218C ( rs1800532) is another SNP in the same intron An intron is any nucleotide sequence within a gene that is not expressed or operative in the final RNA product. The word ''intron'' is derived from the term ''intragenic region'', i.e., a region inside a gene."The notion of the cistron .e., gen ... in the same gene. References {{Reflist SNPs on chromosome 11 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rs1800532
In genetics, rs1800532 (A218C) is a genetic variant. It is a single nucleotide polymorphism in the ''TPH1'' gene and located in intron 7. It has been examined in relation to personality trait In psychology, trait theory (also called dispositional theory) is an approach to the study of human personality. Trait theorists are primarily interested in the measurement of ''traits'', which can be defined as habitual patterns of behavior, thou ...s. A779C is another SNP in same intron. References {{Reflist SNPs on chromosome 11 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
TPH1
Tryptophan hydroxylase 1 (TPH1) is an isoenzyme of tryptophan hydroxylase which in humans is encoded by the ''TPH1'' gene. TPH1 was first discovered to support serotonin synthesis in 1988 by converting tryptophan into 5-hydroxytryptophan. It was thought that there only was a single ''TPH'' gene until 2003. A second form was found in the mouse (''Tph2''), rat and human brain ( TPH2) and the original TPH was then renamed to TPH1. Function Tryptophan hydroxylases catalyze the biopterin-dependent monooxygenation of tryptophan to 5-hydroxytryptophan (5-HTP), which is subsequently decarboxylated by aromatic amino acid decarboxylase to form the neurotransmitter serotonin (5-hydroxytryptamine or 5-HT). It is the rate-limiting enzyme in the biosynthesis of serotonin. TPH expression is limited to a few specialized tissues: raphe neurons, pinealocytes, mast cells, mononuclear leukocytes, beta-cells of the islets of Langerhans, and intestinal and pancreatic enterochromaffin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
A218C
In genetics, rs1800532 (A218C) is a genetic variant. It is a single nucleotide polymorphism in the ''TPH1'' gene and located in intron 7. It has been examined in relation to personality traits. Rs1799913, A779C is another SNP in same intron. References {{Reflist SNPs on chromosome 11 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Res
''Brain Research'' is a peer-reviewed scientific journal focusing on several aspects of neuroscience. It publishes research reports and " minireviews". The editor-in-chief is Matthew J. LaVoie (University of Florida). Until 2011, full reviews were published in ''Brain Research Reviews'', which is now integrated into the main section, albeit with independent volume numbering. In 2006, four other previously established semi-independent journal sections ('' Cognitive Brain Research, Developmental Brain Research, Molecular Brain Research,'' and '' Brain Research Protocols'') were merged with ''Brain Research''. The journal has nine main subsections: * ''Cellular and Molecular Systems'' * ''Nervous System Development, Regeneration and Aging'' * ''Neurophysiology, Neuropharmacology and other forms of Intercellular Communication'' * ''Structural Organization of the Brain'' * ''Sensory and Motor Systems'' * ''Regulatory Systems'' * ''Cognitive and Behavioral Neuroscience'' * ''Disease- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hennig J
Hennig is both a surname and a given name. Notable people with the name include: Surname: * Amy Hennig (born 1964), video game director and writer * Angela Hennig (born 1981), German cyclist *Anke Hennig (born 1964), German politician *Arthur Saxon (born Arthur Hennig, 1878–1921), German strongman and circus performer * Bernard A. Hennig (1917-2014), American philatelist * Carsten Hennig (born 1976), German football player *Curt Hennig (1958–2003), American wrestler known as "Mr. Perfect" * Danielle Hennig (born 1990), Canadian field hockey player * Dennis Hennig (1951–1993), Australian pianist * Edward Hennig (1879–1960), American Olympic gymnast *Edwin Hennig (1882-1977), German paleontologist *Gerd Hennig (1935–2017), German football referee * Heike Hennig (born 1966), German dancer, choreographer and theatre director * Heinz Hennig (1927–2002), German choral conductor * Jack Hennig (born 1946), Canadian singer-songwriter * Joe Hennig (born 1979), American wrestler bet ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Roth S
Roth may refer to: Places Germany * Roth (district), in Bavaria, Germany ** Roth, Bavaria, capital of that district ** Roth (electoral district), a federal electoral district * Rhineland-Palatinate, Germany: ** Roth an der Our, in the district Bitburg-Prüm ** Roth bei Prüm, in the district Bitburg-Prüm ** Roth, Altenkirchen, in the district of Altenkirchen ** Roth, Bad Kreuznach, in the district of Bad Kreuznach ** Roth, Rhein-Hunsrück, in the district Rhein-Hunsrück ** Roth, Rhein-Lahn, in the district Rhein-Lahn-Kreis France * Roth, Moselle, a village in the commune of Hambach, Moselle United States * Roth, Illinois, a community * Roth, North Dakota, a community * Roth, Virginia, a community Rivers * Roth (Danube), a river of Bavaria, Germany, tributary of the Danube * Roth (Rednitz), a river of Bavaria, Germany, tributary of the Rednitz * Roth (Zusam), a river of Bavaria, Germany, tributary of the Zusam * Rot (Apfelstädt), a river also called Roth, of Thuringia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reuter M
Reuter or Reutter is a surname. Notable people with the surname include: Reuter * Christian Reuter (1665– 1712), writer * Edzard Reuter (1928–2024), Daimler-Benz manager * Émile Reuter (1874–1973), Luxembourgian politician * Enzio Reuter (1867–1951), entomologist * Ernst Reuter (1889–1953), mayor of Berlin * Fritz Reuter (1810–1874), poet * Gabriele Reuter (1859–1941), writer * George François Reuter (1805–1872), French botanist * Irving Jacob Reuter (1885–1972), president of Oldsmobile, philanthropist * James B. Reuter (1916–2012), Jesuit priest * Ludwig von Reuter (1869–1943), admiral * Manuel Reuter (born 1961), race driver * Milly Reuter (1904–1976), athlete * Odo Morannal Reuter (1850–1913), Finnish zoologist and poet * Otto Sigfrid Reuter (1876–1945), German writer and neopagan organiser * Paul Reuter (1816–1899), founder of Reuters news agency * Peter Reuter (born 1944), American criminologist * Renan Soares Reuter (born 1990), Brazilian foo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Behavior Genetics (journal)
''Behavior Genetics'' is a bimonthly peer-reviewed scientific journal published by Springer Science+Business Media. It covers "research in the inheritance of behavior" and is the official journal of the Behavior Genetics Association. The journal was established in 1971 with Steven G. Vandenberg as its founding editor-in-chief. He was succeeded by Jan Bruell (1978–1986). Each year, the editorial board chooses a particularly meritorious paper in the previous year's volume of the journal for the Editors' Choice Award, acknowledged by "$1000 and a good bottle of wine" as well as a citation made in the journal. This award was created in the honor of David Fulker, a past president of the Behavior Genetics Association (1982) and former editor-in-chief (1987–1998). From 2001–2025, John K. Hewitt was editor-in-chief. He was succeeded by Valerie Knopik (2025–present). The abstracts of the annual meetings are printed in the journal. Abstracting and indexing The journal is abstracte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mary Jeanne Kreek
Mary Jeanne Kreek (9 February 1937 – March 27, 2021) was an American neurobiologist specializing in the study and treatment of addiction. She is best known for her work with Marie Nyswander and Dr. Vincent Dole in the development of methadone therapy for heroin addiction. Education Kreek graduated with a B.A. in chemistry from Wellesley College in 1958, and in 1962, she received her M.D. from Columbia University College of Physicians and Surgeons. Career Kreek completed a fellowship in gastroenterology at New York Hospital-Cornell Medical Center after completing her M.D. She taught medicine at the Cornell Medical College. In 2000, Kreek was named a Fellow of the New York Academy of Sciences, and in 2004, she received an Alumni Gold Medal Award from Columbia University College of Physicians and Surgeons for "lifetime excellence in medicine". In 2014, Kreek was awarded a Lifetime Achievement Award from the National Institute on Drug Abuse. As of November 2015, she was a seni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Single Nucleotide Polymorphism
In genetics and bioinformatics, a single-nucleotide polymorphism (SNP ; plural SNPs ) is a germline substitution of a single nucleotide at a specific position in the genome. Although certain definitions require the substitution to be present in a sufficiently large fraction of the population (e.g. 1% or more), many publications do not apply such a frequency threshold. For example, a G nucleotide present at a specific location in a reference genome may be replaced by an A in a minority of individuals. The two possible nucleotide variations of this SNP – G or A – are called alleles. SNPs can help explain differences in susceptibility to a wide range of diseases across a population. For example, a common SNP in the CFH gene is associated with increased risk of age-related macular degeneration. Differences in the severity of an illness or response to treatments may also be manifestations of genetic variations caused by SNPs. For example, two common SNPs in the ''A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
