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Rolf Niedergerke
Rolf Nidergerke (30 April 1921 – 27 December 2011) was a German physiologist and physician, and one of the discoverers of the sliding filament theory of muscle contraction. He and Andrew Huxley, complimenting the independent works of Hugh Huxley and Jean Hanson, revealed that muscle contraction is due to shortening of the muscle fibres. He studied medicine throughout the Second World War, and obtained his MD degree as the war ended in 1945. After a brief practise in his hometown, he chose a research career. He became associated with Huxley, whom he joined at Cambridge University. Together they published a landmark paper in ''Nature'' in 1954, which became the foundation of muscle mechanics. Early life and education Rolf Niedergerke was born and educated in Mülheim an der Ruhr. The turmoil of the Second World War almost interrupted his medical course when he was at Freiburg University. As a student of medicine he was exempted from conscription to serve in the German Army. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mülheim An Der Ruhr
Mülheim, officially Mülheim an der Ruhr () and also described as ''"City on the River"'', is a city in North Rhine-Westphalia in Germany. It is located in the Ruhr Area between Duisburg, Essen, Oberhausen and Ratingen. It is home to many companies, especially in the food industry, such as the Aldi Süd Company, the Harke Group and the Tengelmann Group. Mülheim received its town charter in 1808, and 100 years later the population exceeded 100,000, making Mülheim officially a city. At the time of the city's 200th anniversary with approximately 170,000 residents, it was counted among the smaller cities of Germany. Geography Geographical location Mülheim an der Ruhr is located to the southwest of Essen in the Ruhr valley. Geology The northern foothills of the Rhenish Massif are characterised by the distinctive rock formation of the bare mountain slopes through which run coal-bearing layers which formed during the carboniferous period. Here the Ruhr cuts more than 50 me ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Second World War At Sea Series
''Second World War at Sea'' is a game series produced by Avalanche Press covering naval combat during World War II. The series is based on Avalanche Press' '' Great War at Sea''. The two series share many features although they are separate both from a rules standpoint and a scale standpoint (see ''SOPAC'' below). Game Mechanics The SWWAS series simulates World War II naval combat using a dual operational/tactical system with the following characteristics: * Each major surface unit (Aircraft carriers, battleships, cruisers and fleet destroyers) are represented with a single 1"/.5" rectangular counter containing the ship's statistics (below). * Minor surface warships (escorts) as well as auxiliaries and merchant ships, are portrayed via 1/2" square counters with the associated statistics. * Aircraft squadrons (representing from 8–24 aircraft), as well as the game's various status markers, are also 1/2" square counters. The game provides highly abstracted statistics on the various ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nervous System
In Biology, biology, the nervous system is the Complex system, highly complex part of an animal that coordinates its Behavior, actions and Sense, sensory information by transmitting action potential, signals to and from different parts of its body. The nervous system detects environmental changes that impact the body, then works in tandem with the endocrine system to respond to such events. Nervous tissue first arose in Ediacara biota, wormlike organisms about 550 to 600 million years ago. In vertebrates it consists of two main parts, the central nervous system (CNS) and the peripheral nervous system (PNS). The CNS consists of the brain and spinal cord. The PNS consists mainly of nerves, which are enclosed bundles of the long fibers or axons, that connect the CNS to every other part of the body. Nerves that transmit signals from the brain are called motor nerves or ''Efferent nerve fiber, efferent'' nerves, while those nerves that transmit information from the body to the CNS a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurone
A neuron, neurone, or nerve cell is an electrically excitable cell that communicates with other cells via specialized connections called synapses. The neuron is the main component of nervous tissue in all animals except sponges and placozoa. Non-animals like plants and fungi do not have nerve cells. Neurons are typically classified into three types based on their function. Sensory neurons respond to stimuli such as touch, sound, or light that affect the cells of the sensory organs, and they send signals to the spinal cord or brain. Motor neurons receive signals from the brain and spinal cord to control everything from muscle contractions to glandular output. Interneurons connect neurons to other neurons within the same region of the brain or spinal cord. When multiple neurons are connected together, they form what is called a neural circuit. A typical neuron consists of a cell body (soma), dendrites, and a single axon. The soma is a compact structure, and the axon and dendrite ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Robert Stampfli
The sucrose gap technique is used to create a conduction block in nerve or muscle fibers. A high concentration of sucrose is applied to the extracellular space, which prevents the correct opening and closing of sodium and potassium channels, increasing resistance between two groups of cells. It was originally developed by Robert Stämpfli for recording action potentials in nerve fibers, and is particularly useful for measuring irreversible or highly variable pharmacological modifications of channel properties since untreated regions of membrane can be pulled into the node between the sucrose regions. History The sucrose gap technique was first introduced by in 1954 who worked with Alan Hodgkin and Andrew Huxley between 1947 and 1949. From his research, Stämpfli determined that currents moving along nerve fibers can be measured more easily when there is a gap of high resistance that reduces the amount of conducting medium outside of the cell. Stämpfli observed many problems with th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bern
Bern () or Berne; in other Swiss languages, gsw, Bärn ; frp, Bèrna ; it, Berna ; rm, Berna is the ''de facto'' capital of Switzerland, referred to as the " federal city" (in german: Bundesstadt, link=no, french: ville fédérale, link=no, it, città federale, link=no, and rm, citad federala, link=no). According to the Swiss constitution, the Swiss Confederation intentionally has no "capital", but Bern has governmental institutions such as the Federal Assembly and Federal Council. However, the Federal Supreme Court is in Lausanne, the Federal Criminal Court is in Bellinzona and the Federal Administrative Court and the Federal Patent Court are in St. Gallen, exemplifying the federal nature of the Confederation. With a population of about 133,000 (as of 2022), Bern is the fifth-most populous city in Switzerland, behind Zurich, Geneva, Basel and Lausanne. The Bern agglomeration, which includes 36 municipalities, had a population of 406,900 in 2014. The metropolitan ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Blood Circulation
The blood circulatory system is a system of organs that includes the heart, blood vessels, and blood which is circulated throughout the entire body of a human or other vertebrate. It includes the cardiovascular system, or vascular system, that consists of the heart and blood vessels (from Greek ''kardia'' meaning ''heart'', and from Latin ''vascula'' meaning ''vessels''). The circulatory system has two divisions, a systemic circulation or circuit, and a pulmonary circulation or circuit. Some sources use the terms ''cardiovascular system'' and ''vascular system'' interchangeably with the ''circulatory system''. The network of blood vessels are the great vessels of the heart including large elastic arteries, and large veins; other arteries, smaller arterioles, capillaries that join with venules (small veins), and other veins. The circulatory system is closed in vertebrates, which means that the blood never leaves the network of blood vessels. Some invertebrates such as ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurotransmission
Neurotransmission (Latin: ''transmissio'' "passage, crossing" from ''transmittere'' "send, let through") is the process by which signaling molecules called neurotransmitters are released by the axon terminal of a neuron (the presynaptic neuron), and bind to and react with the receptors on the dendrites of another neuron (the postsynaptic neuron) a short distance away. A similar process occurs in retrograde neurotransmission, where the dendrites of the postsynaptic neuron release retrograde neurotransmitters (e.g., endocannabinoids; synthesized in response to a rise in intracellular calcium levels) that signal through receptors that are located on the axon terminal of the presynaptic neuron, mainly at GABAergic and glutamatergic synapses. Neurotransmission is regulated by several different factors: the availability and rate-of-synthesis of the neurotransmitter, the release of that neurotransmitter, the baseline activity of the postsynaptic cell, the number of available posts ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Russian Army
The Russian Ground Forces (russian: Сухопутные войска �ВSukhoputnyye voyska V}), also known as the Russian Army (, ), are the land forces of the Russian Armed Forces. The primary responsibilities of the Russian Ground Forces are the protection of the state borders, combat on land, and the defeat of enemy troops. The President of Russia is the Supreme Commander-in-Chief of the Armed Forces of the Russian Federation. The Commander-in-Chief of the Russian Ground Forces is the chief commanding authority of the Russian Ground Forces. He is appointed by the President of Russia. The Main Command of the Ground Forces is based in Moscow. Mission The primary responsibilities of the Russian Ground Forces are the protection of the state borders, combat on land, the security of occupied territories, and the defeat of enemy troops. The Ground Forces must be able to achieve these goals both in nuclear war and non-nuclear war, especially without the use of weapons of mas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Czech Republic
The Czech Republic, or simply Czechia, is a landlocked country in Central Europe. Historically known as Bohemia, it is bordered by Austria to the south, Germany to the west, Poland to the northeast, and Slovakia to the southeast. The Czech Republic has a hilly landscape that covers an area of with a mostly temperate continental and oceanic climate. The capital and largest city is Prague; other major cities and urban areas include Brno, Ostrava, Plzeň and Liberec. The Duchy of Bohemia was founded in the late 9th century under Great Moravia. It was formally recognized as an Imperial State of the Holy Roman Empire in 1002 and became a kingdom in 1198. Following the Battle of Mohács in 1526, the whole Crown of Bohemia was gradually integrated into the Habsburg monarchy. The Protestant Bohemian Revolt led to the Thirty Years' War. After the Battle of White Mountain, the Habsburgs consolidated their rule. With the dissolution of the Holy Empire in 1806, the C ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Allies Of World War II
The Allies, formally referred to as the United Nations from 1942, were an international military coalition formed during the Second World War (1939–1945) to oppose the Axis powers, led by Nazi Germany, Imperial Japan, and Fascist Italy. Its principal members by 1941 were the United Kingdom, United States, Soviet Union, and China. Membership in the Allies varied during the course of the war. When the conflict broke out on 1 September 1939, the Allied coalition consisted of the United Kingdom, France, and Poland, as well as their respective dependencies, such as British India. They were soon joined by the independent dominions of the British Commonwealth: Canada, Australia, New Zealand and South Africa. Consequently, the initial alliance resembled that of the First World War. As Axis forces began invading northern Europe and the Balkans, the Allies added the Netherlands, Belgium, Norway, Greece, and Yugoslavia. The Soviet Union, which initially ha ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
German Army (Wehrmacht)
The German Army (, "army") is the land component of the armed forces of Federal Republic of Germany, Germany. The present-day German Army was founded in 1955 as part of the newly formed West German ''Bundeswehr'' together with the German Navy, ''Marine'' (German Navy) and the German Air Force, ''Luftwaffe'' (German Air Force). , the German Army had a strength of 62,766 soldiers. History Overview A German army equipped, organized, and trained following a single doctrine and permanently unified under one command in 1871 during the unification of Germany under the leadership of Prussia. From 1871 to 1919, the title ''German Army (German Empire), Deutsches Heer'' (German Army) was the official name of the German land forces. Following the German defeat in World War I and the end of the German Empire, the main army was dissolved. From 1921 to 1935 the name of the German land forces was the ''Reichswehr, Reichsheer'' (Army of the Empire) and from 1935 to 1945 the name ''German Army (We ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
