Robert Walsh (medical Scientist)
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Robert Walsh (medical Scientist)
Robert John Walsh (3 January 1917 - 20 July 1983) was an Australian medical scientist and geneticist. He set up the New South Wales Red Cross Blood Transfusion Service, serving as its inaugural Director for twenty years from 1946 to 1966. From 1973 to 1982, he was the Dean of the Faculty of Medicine at the University of New South Wales. His research activities covered a wide range, including iron metabolism, blood groups, genetic influences on diseases, and improving techniques and equipment for collecting, processing, and transporting blood and its products. In 1982 he was awarded Australia's highest civilian honour, Companion of the Order of Australia, for his services to medicine. Early life and education Walsh was born on 3 January 1917 in East Brisbane, the second of seven children. His parents were John James Walsh, a barrister, and Catherine Mary Walsh (née Ahern). His father was secretary of the University Congress that formed the University of Queensland, which R ...
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University Of New South Wales
The University of New South Wales (UNSW) is a public research university based in Sydney, New South Wales, Australia. It was established in 1949. The university comprises seven faculties, through which it offers bachelor's, master's and doctoral degrees. Its main campus is in the Sydney eastern suburb of Kensington, from the Sydney central business district (CBD). Its creative arts school, UNSW Art & Design (in the faculty of Arts, Design and Architecture), is located in Paddington and it has subcampuses in the Sydney CBD and several other suburbs, including Randwick and Coogee. It has a campus at the Australian Defence Force military academy, ADFA in Canberra, Australian Capital Territory. It has research stations located throughout the state of New South Wales. It is one of the founding members of Group of Eight, a coalition of Australian research-intensive universities and a member of Universitas 21, a global network of research universities. It has international ...
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Nuffield Foundation
The Nuffield Foundation is a charitable trust established in 1943 by William Morris, Lord Nuffield, the founder of Morris Motors Ltd. It aims to improve social well-being by funding research and innovation projects in education and social policy, and building research capacity in science and social science. Its current chief executive is Gavin Kelly. The Foundation's income comes from the interest on its investments and it spends about £10 million on charitable activities each year. It is financially and politically independent and is governed by a board of trustees who meet four times a year. The Foundation makes grants for research and innovation projects that aim to improve the design and operation of social policy, particularly in: *Education *Welfare *Justice It has discontinued its Open Door programme, but remains committed to encouraging original and thought-provoking approaches to research that identify new questions and change the terms of the debate. The Founda ...
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Cystic Fibrosis
Cystic fibrosis (CF) is a genetic disorder inherited in an autosomal recessive manner that impairs the normal clearance of Sputum, mucus from the lungs, which facilitates the colonization and infection of the lungs by bacteria, notably ''Staphylococcus aureus''. CF is a rare genetic disorder that affects mostly the lungs, but also the pancreas, liver, kidneys, and intestine. The hallmark feature of CF is the accumulation of thick mucus in different organs. Long-term issues include Shortness of breath, difficulty breathing and coughing up mucus as a result of frequent pneumonia, lung infections. Other signs and symptoms may include Sinusitis, sinus infections, failure to thrive, poor growth, Steatorrhea, fatty stool, Nail clubbing, clubbing of the fingers and toes, and infertility in most males. Different people may have different degrees of symptoms. Cystic fibrosis is inherited in an autosomal recessive manner. It is caused by the presence of mutations in both copies (alleles) ...
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Australian Academy Of Forensic Sciences
The Australian Academy of Forensic Sciences is a multi-disciplinary learned society founded in 1967 modelled on the British Academy of Forensic Sciences. The Academy conducts regular conferences, undertakes liaison with other Australian professional bodies including medico-legal societies established in Australia, and makes submissions on forensic sciences issues to governments and governmental bodies.Michael Kirby, "Forensic Science - What Have We Learnt". (1987) 20 (1) ''Journal of the Academy of Forensic Science'' p 183 accessed 26 August 2011. Since September 1968, the Academy has published the Australian Journal of Forensic Sciences. The Academy awards the Oscar Rivers Schmalzbach Foundation Research Grants, named in honour of the inaugural Secretary-General of the Academy. History After foundation, the first meeting as an Academy on 3 August 1967 adopted a constitution. The first president of the Academy was Russell Brereton, a judge of the Supreme Court of New South Wa ...
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Emeritus
''Emeritus/Emerita'' () is an honorary title granted to someone who retires from a position of distinction, most commonly an academic faculty position, but is allowed to continue using the previous title, as in "professor emeritus". In some cases, the term is conferred automatically upon all persons who retire at a given rank, but in others, it remains a mark of distinguished performance (usually in the area of research) awarded selectively on retirement. It is also used when a person of distinction in a profession retires or hands over the position, enabling their former rank to be retained in their title. The term ''emeritus'' does not necessarily signify that a person has relinquished all the duties of their former position, and they may continue to exercise some of them. In descriptions of deceased professors emeriti listed at U.S. universities, the title ''emeritus'' is replaced by an indication of the years of their appointments, except in obituaries, where it may be us ...
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Haemochromatosis
Iron overload is the abnormal and increased accumulation of total iron in the body, leading to organ damage. The primary mechanism of organ damage is oxidative stress, as elevated intracellular iron levels increase free radical formation via the Fenton reaction. Iron overload is often ''primary'' (i.e hereditary haemochromatosis, aceruloplasminemia) but may also be ''secondary'' to other causes (i.e. transfusional iron overload). Iron deposition most commonly occurs in the liver, pancreas, skin, heart, and joints. People with iron overload classically present with the triad of liver cirrhosis, secondary diabetes mellitus, and bronze skin. However, due to earlier detection nowadays, symptoms are often limited to general chronic malaise, arthralgia, and hepatomegaly. Signs and symptoms Organs most commonly affected by hemochromatosis include the liver, heart, and endocrine glands. Hemochromatosis may present with the following clinical syndromes: * liver: chronic liver disease ...
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Anaemia
Anemia (also spelt anaemia in British English) is a blood disorder in which the blood has a reduced ability to carry oxygen. This can be due to a lower than normal number of red blood cells, a reduction in the amount of hemoglobin available for oxygen transport, or abnormalities in hemoglobin that impair its function. The name is derived . When anemia comes on slowly, the symptoms are often vague, such as tiredness, weakness, shortness of breath, headaches, and a reduced ability to exercise. When anemia is acute, symptoms may include confusion, feeling like one is going to pass out, loss of consciousness, and increased thirst. Anemia must be significant before a person becomes noticeably pale. Additional symptoms may occur depending on the underlying cause. Anemia can be temporary or long term and can range from mild to severe. Anemia can be caused by blood loss, decreased red blood cell production, and increased red blood cell breakdown. Causes of blood loss inclu ...
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Pathogenesis
In pathology, pathogenesis is the process by which a disease or disorder develops. It can include factors which contribute not only to the onset of the disease or disorder, but also to its progression and maintenance. The word comes . Description Types of pathogenesis include microbial infection, inflammation, malignancy and tissue breakdown. For example, bacterial pathogenesis is the process by which bacteria cause infectious illness. Most diseases are caused by multiple processes. For example, certain cancers arise from dysfunction of the immune system (skin tumors and lymphoma after a renal transplant, which requires immunosuppression), '' Streptococcus pneumoniae'' is spread through contact with respiratory secretions, such as saliva, mucus, or cough droplets from an infected person and colonizes the upper respiratory tract and begins to multiply. The pathogenic mechanisms of a disease (or condition) are set in motion by the underlying causes, which if controlled woul ...
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Albinism
Albinism is the congenital absence of melanin in an animal or plant resulting in white hair, feathers, scales and skin and reddish pink or blue eyes. Individuals with the condition are referred to as albinos. Varied use and interpretation of the terms mean that written reports of albinistic animals can be difficult to verify. Albinism can reduce the survivability of an animal; for example, it has been suggested that albino alligators have an average survival span of only 24 hours due to the lack of protection from UV radiation and their lack of camouflage to avoid predators. It is a common misconception that all albino animals have characteristic pink or red eyes (resulting from the lack of pigment in the Iris (anatomy), iris allowing the blood vessels of the retina to be visible); this is not the case for some forms of albinism. Familiar albino animals include in-bred strains of laboratory animals (rats, mice and rabbits), but populations of naturally occurring albino animals ...
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Hemolytic Anemia
Hemolytic anemia or haemolytic anaemia is a form of anemia due to hemolysis, the abnormal breakdown of red blood cells (RBCs), either in the blood vessels (intravascular hemolysis) or elsewhere in the human body (extravascular). This most commonly occurs within the spleen, but also can occur in the reticuloendothelial system or mechanically (prosthetic valve damage). Hemolytic anemia accounts for 5% of all existing anemias. It has numerous possible consequences, ranging from general symptoms to life-threatening systemic effects. The general classification of hemolytic anemia is either intrinsic or extrinsic. Treatment depends on the type and cause of the hemolytic anemia. Symptoms of hemolytic anemia are similar to other forms of anemia (fatigue and shortness of breath), but in addition, the breakdown of red cells leads to jaundice and increases the risk of particular long-term complications, such as gallstones and pulmonary hypertension. Signs and symptoms Symptoms of hemolytic ...
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Rh Blood Group System
The Rh blood group system is a human blood group system. It contains proteins on the surface of red blood cells. After the ABO blood group system, it is most likely to be involved in transfusion reactions. The Rh blood group system consisted of 49 defined blood group antigens in 2005. there are over 50 antigens, of which the five antigens D, C, c, E, and e are among the most prominent. There is no d antigen. Rh(D) status of an individual is normally described with a ''positive'' (+) or ''negative'' (−) suffix after the ABO type (e.g., someone who is A+ has the A antigen and Rh(D) antigen, whereas someone who is A− has the A antigen but lacks the Rh(D) antigen). The terms ''Rh factor'', ''Rh positive'', and ''Rh negative'' refer to the Rh(D) antigen only. Antibodies to Rh antigens can be involved in hemolytic transfusion reactions and antibodies to the Rh(D) and Rh antigens confer significant risk of hemolytic disease of the newborn. Nomenclature The Rh blood group syst ...
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ABO Blood Group System
The ABO blood group system is used to denote the presence of one, both, or neither of the A and B antigens on erythrocytes (red blood cells). For human blood transfusions, it is the most important of the 47 different blood type (or group) classification systems currently recognized by the International Society of Blood Transfusions (ISBT) as of December 2022. A mismatch in this serotype (or in various others) can cause a potentially fatal adverse reaction after a transfusion, or an unwanted immune response to an organ transplant. Such mismatches are rare in modern medicine. The associated anti-A and anti-B antibodies are usually IgM antibodies, produced in the first years of life by sensitization to environmental substances such as food, bacteria, and viruses. The ABO blood types were discovered by Karl Landsteiner in 1901; he received the Nobel Prize in Physiology or Medicine in 1930 for this discovery. ABO blood types are also present in other primates such as apes, ...
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