Robert A. Kyle
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Robert A. Kyle
Robert A. Kyle is a professor of medicine, Laboratory Medicine and Pathology at the Mayo Clinic. He specializes in the care of patients with plasma cell dyscrasias. Throughout his career Kyle has published more than 1,850 scientific papers and abstracts on myeloma and other plasma cell disorders... Some of Dr. Kyle's most notable scientific contributions include naming the disorder known as Monoclonal gammopathy of undetermined significance (MGUS) as well as establishing the epidemiology and long-term prognosis of MGUS. Education *1961 Hematology Research Fellowship - National Cancer Institute *1958 MS - University of Minnesota *1955 Internal Medicine Residency - Mayo Clinic *1953 Internship - Northwestern University Feinberg School of Medicine *1952 MD - Northwestern University Feinberg School of Medicine *1948 BS - University of North Dakota *1946 AA - Dakota College at Bottineau Personal life Early life Kyle grew up on a rural farm in North Dakota during the 1930s and 1940s. ...
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Mayo Clinic
Mayo Clinic () is a Nonprofit organization, private American Academic health science centre, academic Medical centers in the United States, medical center focused on integrated health care, healthcare, Mayo Clinic College of Medicine and Science, education, and research. It maintains three major campuses in Rochester, Minnesota; Jacksonville, Florida; and Phoenix, Arizona, Phoenix/Scottsdale, Arizona. Mayo Clinic employs over 7,300 physicians and scientists, along with another 66,000 administrative and allied health staff. The practice specializes in treating difficult cases through Health care#Tertiary care, tertiary care and Medical tourism#United States, destination medicine. It is home to the top-15 ranked Mayo Clinic Alix School of Medicine in addition to many of the highest regarded residency education programs in the United States. It spends over $660 million a year on research and has more than 3,000 full-time research personnel. William Worrall Mayo settled his family i ...
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American Society Of Hematology
The American Society of Hematology (ASH) is a professional organization representing hematologists, founded in 1958. Its annual meeting is held in December of every year and has attracted more than 30,000 attendees. The society publishes the medical journal ''Blood'', the most cited peer-reviewed publication in the field, and ''Blood Advances'', an online, peer-reviewed open-access journal. The first official ASH meeting was held in Atlantic City, New Jersey, in April 1958. More than 300 hematologists met together to discuss the key research and clinical issues related to blood and blood diseases. Since the first gathering, ASH has been an important member in the development of hematology as a discipline. For more than six decades, ASH has sponsored its annual meeting. Today, ASH has more than 17,000 members, many of whom have made major advancements in understanding and treating blood diseases. Annual meeting Held each year in December, the annual meeting brings together hema ...
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Walter Reed National Military Medical Center
Walter Reed National Military Medical Center (WRNMMC; formerly known as the National Naval Medical Center and colloquially referred to as Bethesda Naval Hospital, Walter Reed, or Navy Med) is a United States military medical center located in Bethesda, Maryland. It is one of the largest and most prominent military medical centers in the United States, and it has provided medical care for several United States presidents since its opening in 1940. In 2011, the Walter Reed Army Medical Center (WRAMC), named after yellow fever researcher Walter Reed, was combined with the National Naval Medical Center to form today's tri-service Walter Reed National Military Medical Center. It is accessed by the Medical Center station on the Washington Metro's Red Line. History Founding In 1938, the United States Congress appropriated funds for the acquisition of land for the construction of a new naval medical center, and President Franklin D. Roosevelt selected the present site in Beth ...
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Mayo Clinic College Of Medicine And Science
The Mayo Clinic College of Medicine and Science (MCCMS; formerly known as Mayo Clinic College of Medicine) is a private graduate-only research university based in Rochester, Minnesota, United States. It trains physicians, scientists, and allied health professionals. The college is part of the Mayo Clinic academic medical center and is accredited by the Higher Learning Commission (HLC). The college consists of five schools that offer Doctor of Medicine, Doctor of Philosophy, and other degrees, as well as medical resident, medical residencies, Fellowship (medicine), fellowships, and continuing medical education. Organization Mayo Clinic College of Medicine and Science is divided into five schools. Graduate Medical Education The Mayo Clinic School of Graduate Medical Education (MCSGME), established in 1915, offers more than 300 Graduate medical education, residences and fellowships in all medical and surgical specialties with 1,791 active trainees. Medicine The Mayo Clini ...
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Royal College Of Pathologists
The Royal College of Pathologists (RCPath) is a professional membership organisation. Its main function is the overseeing of postgraduate training, and its Fellowship Examination (FRCPath) is recognised as the standard assessment of fitness to practise in this branch of medicine. Constitution The Royal College of Pathologists is a professional membership organisation, to maintain the standards and reputation of British pathology, through training, assessments, examinations and professional development. It is a registered charity and is not a trade union. Its 13,000 members work in hospital laboratories, universities and industry worldwide. History The College of Pathologists was founded in 1962, to optimise postgraduate training in the relatively young science of pathology, with its high importance in the diagnostic process, and the increasing range of specialist studies within it. The college received its royal charter in 1970 and its Patron is King Charles III. Training and e ...
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International Myeloma Foundation
The International Myeloma Foundation (IMF) is an American non-profit organization serving patients with myeloma, a cancer of plasma cells in the bone marrow. The IMF also provides support and information for family members, caregivers of myeloma patients, physicians and nurses. The organization is dedicated to improving the quality of life for all myeloma patients by focusing on four key areas: research, education, support, and advocacy. Founded in 1990 by Brian Novis, Susie Novis, and Brian G.M. Durie, IMF is a 501(c)(3) resource for both patients and caregivers, offering programs that include educational seminars, a patient hotline, multilingual publications, government advocacy, and a web-based Personal Information Management system for recording care and treatment. The IMF is based in North Hollywood, California, and, according to its 2018 annual report, has a membership of 525,000 people in 140 countries. Its motto is "Improving lives — Finding the cure". History The I ...
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Celgene
Celgene Corporation, headquartered in Summit, New Jersey, was a pharmaceutical company that produced cancer and immunology drugs. Its primary products were Revlimid (lenalidomide), which is used in the treatment of multiple myeloma (63% of 2018 revenues); Pomalyst and Imnovid (Pomalidomide), also used in the treatment of multiple myeloma (13% of 2018 revenues); and Otezla (Apremilast), used in the treatment of psoriasis (11% of 2018 revenues). In 2018, 66% of the company's revenues came from the United States. In 2019, the company was acquired by Bristol Myers Squibb (BMS); as part of the acquisition, Otezla was sold to Amgen. History Celgene was originally a unit of Celanese. In 1986, Celanese completed the corporate spin-off of Celgene following the merger of Celanese with Hoechst AG, American Hoechst. In August 2000, Celgene acquired Signal Pharmaceuticals, Inc., a privately held company that developed pharmaceuticals to regulate disease-related genes. Signal Pharmaceuticals w ...
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Weill Cornell Medicine
Weill Cornell Medicine (; officially Joan and Sanford I. Weill Medical College of Cornell University), originally Cornell University Medical College, is the medical school of Cornell University, located on the Upper East Side of Manhattan in New York City. The school and its associated research organization is affiliated with several hospitals and medical centers, including NewYork-Presbyterian Hospital, Weill Cornell Medical Center, Hospital for Special Surgery, Memorial Sloan Kettering Cancer Center, and Rockefeller University, all of which are located on or near York Avenue and Sutton Place. Since 2004, Weill Cornell has also been affiliated with The Methodist Hospital, Houston Methodist Hospital. In 1991, Memorial Sloan Kettering Cancer Center and Rockefeller University joined Weill Cornell to establish the Tri-Institutional MD–PhD Program. In 2001, the school opened the Weill Cornell Medical College in Qatar, a medical school in Qatar. History 19th century The Cornell ...
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American Society Of Clinical Oncology
The American Society of Clinical Oncology (ASCO) is a professional organization representing physicians of all oncology sub-specialties who care for people with cancer. Founded in 1964 by Fred Ansfield, Harry Bisel, Herman Freckman, Arnoldus Goudsmit, Robert Talley, William Wilson, and Jane C. Wright, it has nearly 45,000 members worldwide. Physician education ASCO offers educational resources for cancer physicians and other health care professionals of clinical oncology. These include scientific meetings, educational conferences, professional workshops, and special symposia on issues of particular relevance and importance to oncologists and researchers. It also produced the patient information website, Cancer.Net. It publishes numerous journals, books, newsletters, and online and multimedia resources; it publishes the ''Journal of Clinical Oncology'' (JCO), the '' JCO Oncology Practice'' (JCO OP), and the ''JCO Global Oncology'' (JCO GO), '' JCO Clinical Cancer Informati ...
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Case Western Reserve University
Case Western Reserve University (CWRU) is a Private university, private research university in Cleveland, Ohio, United States. It was established in 1967 by a merger between Western Reserve University and the Case Institute of Technology. Case Western Reserve University comprises eight schools that offer more than 100 undergraduate programs and about 160 graduate and professional options across fields in STEM, medicine, arts, and the humanities. In 2024, the university enrolled 12,475 students (6,528 undergraduate plus 5,947 graduate and professional) from all 50 states and 106 countries and employed more than 1,182 full-time faculty members. The university's athletic teams, Case Western Reserve Spartans, play in NCAA Division III as a founding member of the University Athletic Association. Case Western Reserve University is a member of the Association of American Universities and is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Univ ...
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Mayo Clinic Alix School Of Medicine
The Mayo Clinic Alix School of Medicine (MCASOM), formerly known as Mayo Medical School (MMS), is a research-oriented medical school based in Rochester, Minnesota, with additional campuses in Arizona and Florida. MCASOM is a school within the Mayo Clinic College of Medicine and Science (MCCMS), the education division of the Mayo Clinic. It grants the Doctor of Medicine (M.D.) degree, accredited by the Higher Learning Commission (HLC) and the Liaison Committee on Medical Education (LCME). In November 2018, the school was renamed in honor of a $200 million donation from businessman Jay Alix. Rankings As of 2021, U.S. News & World Report ranks Mayo Clinic Alix School of Medicine #11 (tie) on their "Best Medical Schools: Research" list. MCASOM is the most selective medical school in the United States, with the lowest acceptance rate (2.1%) among schools submitting data for the 2017-2018 application cycle. In 2017, medical students had the highest USMLE Step 1 board scores in the na ...
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Plasma Cell
Plasma cells, also called plasma B cells or effector B cells, are white blood cells that originate in the lymphoid organs as B cells and secrete large quantities of proteins called antibodies in response to being presented specific substances called antigens. These antibodies are transported from the plasma cells by the blood plasma and the lymphatic system to the site of the target antigen (foreign substance), where they initiate its neutralization or destruction. B cells differentiate into plasma cells that produce antibody molecules closely modeled after the receptors of the precursor B cell. Structure Plasma cells are large lymphocytes with abundant cytoplasm and a characteristic appearance on light microscopy. They have basophilic cytoplasm and an eccentric nucleus with heterochromatin in a characteristic cartwheel or clock face arrangement. Their cytoplasm also contains a pale zone that on electron microscopy contains an extensive Golgi apparatus and centrioles. Abundan ...
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