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Richard Laurence Millington Synge
Richard Laurence Millington Synge (28 October 1914 – 18 August 1994) was a British biochemist, and shared the 1952 Nobel Prize in Chemistry for the invention of partition chromatography with Archer Martin. Life Richard Laurence Millington Synge was born in West Kirby on 28 October 1914, the son of Lawrence Millington Synge, a Liverpool stock-broker, and his wife, Katherine C. Swan. Synge was educated at the Old Hall in Wellington, Shropshire and at Winchester College. He then studied Chemistry at Trinity College, Cambridge. He spent his entire career in research, at the Wool Industries Research Association, Leeds (1941–1943), Lister Institute for Preventive Medicine, London (1943–1948), Rowett Research Institute, Aberdeen (1948–1967), and Food Research Institute, Norwich (1967–1976). It was during his time in Leeds that he worked with Archer Martin, developing partition chromatography, a technique used in the separation mixtures of similar chemicals, that r ...
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Liverpool
Liverpool is a port City status in the United Kingdom, city and metropolitan borough in Merseyside, England. It is situated on the eastern side of the River Mersey, Mersey Estuary, near the Irish Sea, north-west of London. With a population of (in ), Liverpool is the administrative, cultural and economic centre of the Liverpool City Region, a combined authority, combined authority area with a population of over 1.5 million. Established as a borough in Lancashire in 1207, Liverpool became significant in the late 17th century when the Port of Liverpool was heavily involved in the Atlantic slave trade. The port also imported cotton for the Textile manufacture during the British Industrial Revolution, Lancashire textile mills, and became a major departure point for English and Irish emigrants to North America. Liverpool rose to global economic importance at the forefront of the Industrial Revolution in the 19th century and was home to the Liverpool and Manchester Railway, firs ...
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Institute Of Food Research
The Quadram Institute is a centre for food and health research, combining Quadram Institute Bioscience (formerly the Institute of Food Research), the Norfolk and Norwich University Hospitals' endoscopy centre and aspects of the University of East Anglia's Norwich Medical School and the Faculty of Science. It is located on the outskirts of Norwich, England, and is a member of the Norwich Research Park. The institute is housed in a purpose-built facility on the Norwich Research Park that opened in 2018. Its founding partners are Quadram Institute Bioscience, University of East Anglia, Norfolk and Norwich University Hospital and the Biotechnology and Biological Sciences Research Council. The institute combines research teams from the partners with a regional gastrointestinal endoscopy unit and a clinical trials facility. The first patients were treated in the endoscopy unit in December 2018. History The Institute of Food Research was created in 1968, spread over four sites; th ...
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Royal Society Of Chemistry
The Royal Society of Chemistry (RSC) is a learned society and professional association in the United Kingdom with the goal of "advancing the chemistry, chemical sciences". It was formed in 1980 from the amalgamation of the Chemical Society, the Royal Institute of Chemistry, the Faraday Society, and the Society for Analytical Chemistry with a new Royal Charter and the dual role of learned society and professional body. At its inception, the Society had a combined membership of 49,000 in the world. The headquarters of the Society are at Burlington House, Piccadilly, London. It also has offices in Thomas Graham House in Cambridge (named after Thomas Graham (chemist), Thomas Graham, the first president of the Chemical Society) where ''RSC Publishing'' is based. The Society has offices in the United States, on the campuses of The University of Pennsylvania and Drexel University, at the University City Science Center in Philadelphia, Pennsylvania, in both Beijing and Shanghai, People' ...
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John Andrew Crichton
John is a common English name and surname: * John (given name) * John (surname) John may also refer to: New Testament Works * Gospel of John, a title often shortened to John * First Epistle of John, often shortened to 1 John * Second Epistle of John, often shortened to 2 John * Third Epistle of John, often shortened to 3 John People * John the Baptist (died ), regarded as a prophet and the forerunner of Jesus Christ * John the Apostle (died ), one of the twelve apostles of Jesus Christ * John the Evangelist, assigned author of the Fourth Gospel, once identified with the Apostle * John of Patmos, also known as John the Divine or John the Revelator, the author of the Book of Revelation, once identified with the Apostle * John the Presbyter, a figure either identified with or distinguished from the Apostle, the Evangelist and John of Patmos Other people with the given name Religious figures * John, father of Andrew the Apostle and Saint Peter * Pope John (disambigu ...
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David Cuthbertson
Sir David Paton Cuthbertson, CBE, FRSE (9 May 1900 – 15 April 1989) was a Scottish physician, biochemist, medical researcher and nutritionist who was a leading authority on metabolism. The Rowett Research Institute became one of the world's leading centres for animal nutrition research under Cuthbertson's leadership (1945–65). Life David Cuthbertson was born in Kilmarnock the son of John Cuthbertson FRSE (1859–1933) a teacher in the fields of both mining and agriculture. David was educated at Kilmarnock Academy. He served in the Royal Scots Fusiliers during the First World War. This delayed his education and he then studied medicine at Glasgow University graduating MB ChB in 1926. Cuthbertson served on several research and scientific committees, including secondment to the Medical Research Council in 1943, and served as vice-president of the Royal Society of Edinburgh from 1959 to 1960. In his early research, in 1936, Cuthbertson observed a loss of nitrogen (urea) ...
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Magnus Pyke
Magnus Alfred Pyke (29 December 1908 – 19 October 1992) was an English nutritional scientist, governmental scientific adviser, writer and presenter. He worked for the UK Ministry of Food, the post-war Allied Commission for Austria, and different food manufacturers. He wrote prolifically and became famous as a TV and radio personality, and was featured on Thomas Dolby's 1982 synth-pop hit, "She Blinded Me with Science". Early life and scientific career Pyke was born at Gloucester Terrace, Paddington, London, the son of Clara Hannah Lewis and Robert Bond Pyke, manager of a wholesale confectionery business. He went to St. Paul's School, Barnes, London, where he found he had a "certain bounciness combined with a lack of self-consciousness." He worked briefly for an insurance company before moving to Canada to attend Macdonald College, McGill University, Montreal, studying agriculture, gaining a BSc in 1933. During summers there, he worked as a farm labourer. He remained ...
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Royal Society Of Edinburgh
The Royal Society of Edinburgh (RSE) is Scotland's national academy of science and letters. It is a registered charity that operates on a wholly independent and non-partisan basis and provides public benefit throughout Scotland. It was established in 1783. , there are around 1,800 Fellows. The Society covers a broader range of fields than the Royal Society of London, including literature and history. The Fellowship includes people from a wide range of disciplines: science and technology, arts, humanities, medicine, social science, business, and public service. History At the start of the 18th century, Edinburgh's intellectual climate fostered many clubs and societies (see Scottish Enlightenment). Though there were several that treated the arts, sciences and medicine, the most prestigious was the Society for the Improvement of Medical Knowledge, commonly referred to as the Medical Society of Edinburgh, co-founded by the mathematician Colin Maclaurin in 1731. Maclaurin was u ...
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Fellow Of The Royal Society
Fellowship of the Royal Society (FRS, ForMemRS and HonFRS) is an award granted by the Fellows of the Royal Society of London to individuals who have made a "substantial contribution to the improvement of natural science, natural knowledge, including mathematics, engineering science, and medical science". Overview Fellowship of the Society, the oldest known scientific academy in continuous existence, is a significant honour. It has been awarded to :Fellows of the Royal Society, around 8,000 fellows, including eminent scientists Isaac Newton (1672), Benjamin Franklin (1756), Charles Babbage (1816), Michael Faraday (1824), Charles Darwin (1839), Ernest Rutherford (1903), Srinivasa Ramanujan (1918), Jagadish Chandra Bose (1920), Albert Einstein (1921), Paul Dirac (1930), Subrahmanyan Chandrasekhar (1944), Prasanta Chandra Mahalanobis (1945), Dorothy Hodgkin (1947), Alan Turing (1951), Lise Meitner (1955), Satyendra Nath Bose (1958), and Francis Crick (1959). More recently, fellow ...
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Insulin
Insulin (, from Latin ''insula'', 'island') is a peptide hormone produced by beta cells of the pancreatic islets encoded in humans by the insulin (''INS)'' gene. It is the main Anabolism, anabolic hormone of the body. It regulates the metabolism of carbohydrates, fats, and protein by promoting the absorption of glucose from the blood into cells of the liver, fat cell, fat, and skeletal muscles. In these tissues the absorbed glucose is converted into either glycogen, via glycogenesis, or Fatty acid metabolism#Glycolytic end products are used in the conversion of carbohydrates into fatty acids, fats (triglycerides), via lipogenesis; in the liver, glucose is converted into both. Glucose production and secretion by the liver are strongly inhibited by high concentrations of insulin in the blood. Circulating insulin also affects the synthesis of proteins in a wide variety of tissues. It is thus an anabolic hormone, promoting the conversion of small molecules in the blood into large ...
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Frederick Sanger
Frederick Sanger (; 13 August 1918 – 19 November 2013) was a British biochemist who received the Nobel Prize in Chemistry twice. He won the 1958 Chemistry Prize for determining the amino acid sequence of insulin and numerous other proteins, demonstrating in the process that each had a unique, definite structure; this was a foundational discovery for the central dogma of molecular biology. At the newly constructed Laboratory of Molecular Biology in Cambridge, he developed and subsequently refined the first-ever DNA sequencing technique, which vastly expanded the number of feasible experiments in molecular biology and remains in widespread use today. The breakthrough earned him the 1980 Nobel Prize in Chemistry, which he shared with Walter Gilbert and Paul Berg. He is one of only three people to have won multiple Nobel Prizes in the same category (the others being John Bardeen in physics and Karl Barry Sharpless in chemistry), and one of five persons with two Nobel ...
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Gramicidin
Gramicidin, also called gramicidin D, is a mix of ionophoric antibiotics, gramicidin A, B and C, which make up about 80%, 5%, and 15% of the mix, respectively. Each has 2 isoforms, so the mix has 6 different types of gramicidin molecules. They can be extracted from ''Brevibacillus brevis'' soil bacteria. Gramicidins are linear peptides with 15 amino acids. This is in contrast to unrelated gramicidin S, which is a cyclic peptide. Medical uses Gramicidins work as antibiotics against gram-positive bacteria like ''Bacillus subtilis'' and ''Staphylococcus aureus'', but not well against gram-negative ones like ''E. coli''. Gramicidins are used in medicinal lozenges for sore throat and in topical medicines to treat infected wounds. Gramicidins are often mixed with other antibiotics like tyrocidine and antiseptics. Gramicidins are also used in eye drops for bacterial eye infections. In drops, they are often mixed with other antibiotics like polymyxin B or neomycin. Multiple antibio ...
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Peptide
Peptides are short chains of amino acids linked by peptide bonds. A polypeptide is a longer, continuous, unbranched peptide chain. Polypeptides that have a molecular mass of 10,000 Da or more are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. Peptides fall under the broad chemical classes of biological polymers and oligomers, alongside nucleic acids, oligosaccharides, polysaccharides, and others. Proteins consist of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, to another protein or other macromolecule such as DNA or RNA, or to complex macromolecular assemblies. Amino acids that have been incorporated into peptides are termed residues. A water molecule is released during formation of each amide bond.. All peptides except cyclic peptides have an N-terminal (amine group) and C-terminal (carboxyl g ...
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