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Research Triangle Institute
Research Triangle Institute, operating as RTI International, is a nonprofit organization headquartered in the Research Triangle Park in North Carolina, USA. RTI provides research and technical services. It was founded in 1958 with $500,000 in funding from local businesses and the three North Carolina universities that form the Research Triangle. RTI research has covered topics like HIV/AIDS, healthcare, education curriculum and the environment. History In 1954, a building contractor, met with the North Carolina state treasurer and the president of Wachovia to discuss building a research park in North Carolina to attract new industries to the region. They obtained support for the concept from the state governor, Luther Hodges, and the three universities that form the research triangle: University of North Carolina at Chapel Hill, Duke University and North Carolina State University. The Research Triangle Institute (now RTI International) was formed by the park's founders as the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
501(c)3 Organization
__NOTOC__ Year 501 (Roman numerals, DI) was a common year starting on Monday of the Julian calendar. At the time, it was known as the Year of the Consulship of Avienus (consul 501), Avienus and Pompeius (consul 501), Pompeius (or, less frequently, year 1254 ''Ab urbe condita''). The denomination 501 for this year has been used since the early medieval period, when the Anno Domini calendar era became the prevalent method in Europe for naming years. Events By place Britannia * Domangart Réti succeeds his father Fergus Mór, after he dies during a campaign against the Picts. He becomes the new king of Dál Riata (modern Scotland) (according to the ''Annals of Tigernach''). Europe * Burgundian Civil War: King Gundobad breaks his promise of tribute and regains his military power. He besieges his brother Godegisel at the city of Vienne, Isère, Vienne (Kingdom of Burgundy, Burgundy), and murders him in an Arianism, Arian church along with the bishop.Gregory of Tours, ''H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
NASA
The National Aeronautics and Space Administration (NASA ) is an independent agencies of the United States government, independent agency of the federal government of the United States, US federal government responsible for the United States's civil list of government space agencies, space program, aeronautics research and outer space, space research. National Aeronautics and Space Act, Established in 1958, it succeeded the National Advisory Committee for Aeronautics (NACA) to give the American space development effort a distinct civilian orientation, emphasizing peaceful applications in space science. It has since led most of America's space exploration programs, including Project Mercury, Project Gemini, the 1968–1972 Apollo program missions, the Skylab space station, and the Space Shuttle. Currently, NASA supports the International Space Station (ISS) along with the Commercial Crew Program and oversees the development of the Orion (spacecraft), Orion spacecraft and the Sp ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
US Department Of Energy
US or Us most often refers to: * Us (pronoun), ''Us'' (pronoun), the objective case of the English first-person plural pronoun ''we'' * US, an abbreviation for the United States US, U.S., Us, us, or u.s. may also refer to: Arts and entertainment Albums * Us (Brother Ali album), ''Us'' (Brother Ali album) or the title song, 2009 * Us (Empress Of album), ''Us'' (Empress Of album), 2018 * Us (Mull Historical Society album), ''Us'' (Mull Historical Society album), 2003 * Us (Peter Gabriel album), ''Us'' (Peter Gabriel album), 1992 * Us (EP), ''Us'' (EP), by Moon Jong-up, 2021 * ''Us'', by Maceo Parker, 1974 * ''Us'', mini-album by Peakboy, 2019 Songs * Us (James Bay song), "Us" (James Bay song), 2018 * Us (Jennifer Lopez song), "Us" (Jennifer Lopez song), 2018 * Us (Regina Spektor song), "Us" (Regina Spektor song), 2004 * Us (Gracie Abrams song), "Us" (Gracie Abrams song), 2024 * "Us", by Azealia Banks from ''Fantasea (mixtape), Fantasea'', 2012 * "Us", by Celine Dion from ''Let's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Love Canal
Love Canal was a neighborhood in Niagara Falls, New York, United States, infamous as the location of a landfill that became the site of an environmental disaster discovered in 1977. Decades of dumping toxic chemicals killed residents and harmed the health of hundreds, often profoundly. The area was cleaned up over 21 years in a Superfund operation. In 1890, Love Canal was created as a model planned community, but was only partially developed. In 1894, work was begun on a canal that would have linked lakes Erie and Ontario, but it was abandoned after only was dug. In the 1920s, the canal became a dump site for municipal refuse for the city of Niagara Falls. During the 1940s, the canal was purchased by Hooker Chemical Company, which used the site to dump 19,800 metric tonnes of chemical byproducts from the manufacturing of dyes, perfumes, and solvents for rubber and synthetic resins. Love Canal was sold to the Niagara Falls City School District, local school district in 1953 f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Institutes Of Health
The National Institutes of Health (NIH) is the primary agency of the United States government responsible for biomedical and public health research. It was founded in 1887 and is part of the United States Department of Health and Human Services (HHS). Many NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its scientific research through the NIH Intramural Research Program (IRP) and provides significant biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research institution in the world, while, as of 2003, the extramural arm provided 28% of biomedical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Cancer Institute
The National Cancer Institute (NCI) coordinates the United States National Cancer Program and is part of the National Institutes of Health (NIH), which is one of eleven agencies that are part of the U.S. Department of Health and Human Services. The NCI conducts and supports research, training, health information dissemination, and other activities related to the causes, prevention, diagnosis, and treatment of cancer; the supportive care of cancer patients and their families; and cancer survivorship. NCI is the oldest and has the largest budget and research program of the 27 institutes and centers of the NIH ($6.9 billion in 2020). It fulfills the majority of its mission via an extramural program that provides grants for cancer research. Additionally, the National Cancer Institute has intramural research programs in Bethesda, Maryland, and at the Frederick National Laboratory for Cancer Research at Fort Detrick in Frederick, Maryland. The NCI receives more than in funding e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Taxol
Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. It is administered by intravenous injection. There is also an protein-bound paclitaxel, albumin-bound formulation. Common side effects include hair loss, bone marrow suppression, numbness, allergic reactions, muscle pains, and diarrhea. Other side effects include heart problems, increased risk of infection, and pneumonitis, lung inflammation. There are concerns that use during pregnancy may cause birth defects. Paclitaxel is in the taxane family of medications. It works by interference with the normal function of microtubules during cell division. Paclitaxel was isolated in 1971 from the Pacific yew and approved for medical use in 1993. It is on the World Health Organization's List of Essential Medicines. It has been made from precursors, and through cell c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Camptotheca
''Camptotheca'' (happy tree, cancer tree, or tree of life) is a genus of medium-sized deciduous trees growing to tall, native to southern China and Tibet. The genus is usually included in the tupelo family Nyssaceae, but sometimes included (with the tupelos) in the dogwood family Cornaceae. The name "happy tree" is a direct translation of the Chinese name xǐ shù (Simplified Chinese:喜树). There are two species: *''Camptotheca acuminata'' Decne. *''Camptotheca lowreyana'' S.Y.Li The bark and stems of ''C. acuminata'' contain the alkaloid camptothecin. Several chemical derivatives of camptothecin are under investigation for or used as drugs for cancer treatment, including irinotecan, topotecan, rubitecan. ''C. acuminata'' also contains the chemical compounds trifolin and hyperoside Hyperoside is a chemical compound. It is the 3-''O''-galactoside of quercetin. Natural occurrences Hyperoside has been isolated from ''Drosera rotundifolia'', from the Lamiaceae ''Stachys s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Camptothecin
Camptothecin (CPT) is a topoisomerase inhibitor. It was discovered in 1966 by M. E. Wall and M. C. Wani in systematic screening of natural products for anticancer drugs. It was isolated from the Bark (botany), bark of ''Camptotheca acuminata'' (喜树 "Happy tree"), a tree native to China used in traditional Chinese medicine. It has been used clinically in China for the treatment of gastrointestinal tumors. CPT showed anticancer activity in preliminary clinical trials, especially against breast, ovarian, colon, lung, and stomach cancers. However, it has low solubility and adverse effects have been reported when used therapeutically, so synthetic and medicinal chemists have developed numerous syntheses of camptothecin and various derivatives to increase the benefits of the chemical, with good results. Four CPT Analog (chemistry), analogues have been approved and are used in cancer chemotherapy today: topotecan, irinotecan, belotecan, and trastuzumab deruxtecan. Camptothecin has als ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mansukh C
Mansukh () Mansukh is an Indian masculine given name derived from a Sanskrit word meaning "happy heart". Notable people of this name include: *Mansukh Bhuva Mansukh Bhuva is a Member of Legislative assembly from Dhari constituency in Gujarat Gujarat () is a States of India, state along the Western India, western coast of India. Its coastline of about is the longest in the country, most of ..., Indian politician * Mansukh L. Mandaviya (b. 1972), Indian politician * Mansukh C. Wani (d. 2020), Indian academic and organic chemist *Bhai Mansukh, Sikh, disciple of Guru Nanak References {{given name, type=both Indian masculine given names Masculine given names ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monroe Wall
Monroe Eliot Wall (1916 – July 6, 2002) was an American chemist, who co-discovered, with Mansukh C. Wani, paclitaxel and camptothecin, two anti-cancer drugs considered standard in the treatment to fight ovarian, breast, lung and colon cancers. On May 27, 1987, Wall received an honorary doctorate from the faculty of pharmacy at Uppsala University, Sweden. Wall was born in Newark, New Jersey, in 1916. He completed his BS, MS, and PhD at Rutgers University. He joined the United States Department of Agriculture (USDA) in 1941 and worked at the USDA until 1960. That year, he started a research group at RTI International Research Triangle Institute, operating as RTI International, is a nonprofit organization headquartered in the Research Triangle Park in North Carolina, USA. RTI provides research and technical services. It was founded in 1958 with $500,000 in fu ..., where he remained for the duration of his career. References External linksMonroe E. Wall, National Cancer In ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Laboratory Certification Program
National may refer to: Common uses * Nation or country ** Nationality – a ''national'' is a person who is subject to a nation, regardless of whether the person has full rights as a citizen Places in the United States * National, Maryland, census-designated place * National, Nevada, ghost town * National, Utah, ghost town * National, West Virginia, unincorporated community Commerce * National (brand), a brand name of electronic goods from Panasonic * National Benzole (or simply known as National), former petrol station chain in the UK, merged with BP * National Book Store, a bookstore and office supplies chain in the Philippines * National Car Rental, an American rental car company * National Energy Systems, a former name of Eco Marine Power * National Entertainment Commission, a former name of the Media Rating Council * National Motor Vehicle Company, Indianapolis, Indiana, USA 1900–1924 * National Radio Company, Malden, Massachusetts, USA 1914–1991 * National Supermarket ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
