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Repeated Measures Design
Repeated measures design is a research design that involves multiple measures of the same variable taken on the same or matched subjects either under different conditions or over two or more time periods. For instance, repeated measurements are collected in a longitudinal study in which change over time is assessed. Crossover studies A popular repeated-measures design is the crossover study. A crossover study is a longitudinal study in which subjects receive a sequence of different treatments (or exposures). While crossover studies can be observational studies, many important crossover studies are controlled experiments. Crossover designs are common for experiments in many scientific disciplines, for example psychology, education, pharmaceutical science, and health care, especially medicine. Randomized, controlled, crossover experiments are especially important in health care. In a randomized clinical trial, the subjects are randomly assigned treatments. When such a trial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Research Design
Research design refers to the overall strategy utilized to answer research questions. A research design typically outlines the theories and models underlying a project; the research question(s) of a project; a strategy for gathering data and information; and a strategy for producing answers from the data. A strong research design yields valid answers to research questions while weak designs yield unreliable, imprecise or irrelevant answers. Incorporated in the design of a research study will depend on the standpoint of the researcher over their beliefs in the nature of knowledge (see epistemology) and reality (see ontology), often shaped by the Academic discipline, disciplinary areas the researcher belongs to. The design of a study defines the study type (descriptive, correlational, semi-experimental, experimental, review, meta-analytic) and sub-type (e.g., descriptive-longitudinal case study), research problem, Hypothesis, hypotheses, Dependent and independent variables, indepen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Order Effect
Order, ORDER or Orders may refer to: * A socio-political or established or existing order, e.g. World order, Ancien Regime, Pax Britannica * Categorization, the process in which ideas and objects are recognized, differentiated, and understood * Heterarchy, a system of organization wherein the elements have the potential to be ranked a number of different ways * Hierarchy, an arrangement of items that are represented as being "above", "below", or "at the same level as" one another * an action or inaction that must be obeyed, mandated by someone in authority People * Orders (surname) Arts, entertainment, and media * ''Order'' (film), a 2005 Russian film * ''Order'' (album), a 2009 album by Maroon * "Order", a 2016 song from '' Brand New Maid'' by Band-Maid * ''Orders'' (1974 film), a film by Michel Brault * "Orders" (''Star Wars: The Clone Wars'') Business * Blanket order, a purchase order to allow multiple delivery dates over a period of time * Money order or postal orde ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial Protocol
In natural and social science research, a protocol is most commonly a predefined procedural method in the design and implementation of an experiment. Protocols are written whenever it is desirable to standardize a laboratory method to ensure successful replication of results by others in the same laboratory or by other laboratories. Additionally, and by extension, protocols have the advantage of facilitating the assessment of experimental results through peer review. In addition to detailed procedures, equipment, and instruments, protocols will also contain study objectives, reasoning for experimental design, reasoning for chosen sample sizes, safety precautions, and how results were calculated and reported, including statistical analysis and any rules for predefining and documenting excluded data to avoid bias. Similarly, a protocol may refer to the procedural methods of health organizations, commercial laboratories, manufacturing plants, etc. to ensure their activities (e.g., ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Analysis Of Variance
Analysis of variance (ANOVA) is a family of statistical methods used to compare the Mean, means of two or more groups by analyzing variance. Specifically, ANOVA compares the amount of variation ''between'' the group means to the amount of variation ''within'' each group. If the between-group variation is substantially larger than the within-group variation, it suggests that the group means are likely different. This comparison is done using an F-test. The underlying principle of ANOVA is based on the law of total variance, which states that the total variance in a dataset can be broken down into components attributable to different sources. In the case of ANOVA, these sources are the variation between groups and the variation within groups. ANOVA was developed by the statistician Ronald Fisher. In its simplest form, it provides a statistical test of whether two or more population means are equal, and therefore generalizes the Student's t-test#Independent two-sample t-test, ''t''- ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mixed Model
A mixed model, mixed-effects model or mixed error-component model is a statistical model containing both fixed effects and random effects. These models are useful in a wide variety of disciplines in the physical, biological and social sciences. They are particularly useful in settings where repeated measures design, repeated measurements are made on the same statistical units (see also longitudinal study), or where measurements are made on clusters of related statistical units. Mixed models are often preferred over traditional analysis of variance regression models because they don't rely on the independent observations assumption. Further, they have their flexibility in dealing with missing values and uneven spacing of repeated measurements. The Mixed model analysis allows measurements to be explicitly modeled in a wider variety of correlation and variance-covariance variance, avoiding biased estimations structures. This page will discuss mainly linear mixed-effects models rathe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Effect Size
In statistics, an effect size is a value measuring the strength of the relationship between two variables in a population, or a sample-based estimate of that quantity. It can refer to the value of a statistic calculated from a sample of data, the value of one parameter for a hypothetical population, or to the equation that operationalizes how statistics or parameters lead to the effect size value. Examples of effect sizes include the correlation between two variables, the regression coefficient in a regression, the mean difference, or the risk of a particular event (such as a heart attack) happening. Effect sizes are a complement tool for statistical hypothesis testing, and play an important role in power analyses to assess the sample size required for new experiments. Effect size are fundamental in meta-analyses which aim to provide the combined effect size based on data from multiple studies. The cluster of data-analysis methods concerning effect sizes is referred to as estima ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Greenhouse–Geisser Correction
The Greenhouse–Geisser correction \widehat is a statistical method of adjusting for lack of sphericity in a repeated measures ANOVA. The correction functions as both an estimate of epsilon (sphericity) and a correction for lack of sphericity. The correction was proposed by Samuel Greenhouse and Seymour Geisser in 1959. The Greenhouse–Geisser correction is an estimate of sphericity (\widehat). If sphericity is met, then \varepsilon = 1 . If sphericity is not met, then epsilon will be less than 1 (and the degrees of freedom will be overestimated and the F-value will be inflated). To correct for this inflation, multiply the Greenhouse–Geisser estimate of epsilon to the degrees of freedom used to calculate the F critical value. An alternative correction that is believed to be less conservative is the Huynh–Feldt correction (1976). As a general rule of thumb, the Greenhouse–Geisser correction is the preferred correction method when the epsilon estimate is below 0.75. Other ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
F Statistic
An F-test is a statistical test that compares variances. It is used to determine if the variances of two samples, or if the ratios of variances among multiple samples, are significantly different. The test calculates a statistic, represented by the random variable F, and checks if it follows an F-distribution. This check is valid if the null hypothesis is true and standard assumptions about the errors (ε) in the data hold. F-tests are frequently used to compare different statistical models and find the one that best describes the population the data came from. When models are created using the least squares method, the resulting F-tests are often called "exact" F-tests. The F-statistic was developed by Ronald Fisher in the 1920s as the variance ratio and was later named in his honor by George W. Snedecor. Common examples Common examples of the use of ''F''-tests include the study of the following cases * The hypothesis that the means of a given set of normally distributed po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mauchly's Sphericity Test
Mauchly's sphericity test or Mauchly's ''W'' is a statistical test used to validate a repeated measures analysis of variance (ANOVA). It was developed in 1940 by John Mauchly. Sphericity Sphericity is an important assumption of a repeated-measures ANOVA. It is the condition of equal variances among the differences between all possible pairs of within-subject conditions (i.e., levels of the independent variable). If sphericity is violated (i.e., if the variances of the differences between all combinations of the conditions are not equal), then the variance calculations may be distorted, which would result in an inflated F-ratio. Sphericity can be evaluated when there are three or more levels of a repeated measure factor and, with each additional repeated measures factor, the risk for violating sphericity increases. If sphericity is violated, a decision must be made as to whether a univariate or multivariate analysis is selected. If a univariate method is selected, the repeated-mea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Normal Distribution
In probability theory and statistics, a normal distribution or Gaussian distribution is a type of continuous probability distribution for a real-valued random variable. The general form of its probability density function is f(x) = \frac e^\,. The parameter is the mean or expectation of the distribution (and also its median and mode), while the parameter \sigma^2 is the variance. The standard deviation of the distribution is (sigma). A random variable with a Gaussian distribution is said to be normally distributed, and is called a normal deviate. Normal distributions are important in statistics and are often used in the natural and social sciences to represent real-valued random variables whose distributions are not known. Their importance is partly due to the central limit theorem. It states that, under some conditions, the average of many samples (observations) of a random variable with finite mean and variance is itself a random variable—whose distribution c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Type 1 Error
Type I error, or a false positive, is the erroneous rejection of a true null hypothesis in statistical hypothesis testing. A type II error, or a false negative, is the erroneous failure in bringing about appropriate rejection of a false null hypothesis. Type I errors can be thought of as errors of commission, in which the status quo is erroneously rejected in favour of new, misleading information. Type II errors can be thought of as errors of omission, in which a misleading status quo is allowed to remain due to failures in identifying it as such. For example, if the assumption that people are ''innocent until proven guilty'' were taken as a null hypothesis, then proving an innocent person as guilty would constitute a Type I error, while failing to prove a guilty person as guilty would constitute a Type II error. If the null hypothesis were inverted, such that people were by default presumed to be ''guilty until proven innocent'', then proving a guilty person's innocence would c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
F-test
An F-test is a statistical test that compares variances. It is used to determine if the variances of two samples, or if the ratios of variances among multiple samples, are significantly different. The test calculates a Test statistic, statistic, represented by the random variable F, and checks if it follows an F-distribution. This check is valid if the null hypothesis is true and standard assumptions about the errors (ε) in the data hold. F-tests are frequently used to compare different statistical models and find the one that best describes the population (statistics), population the data came from. When models are created using the least squares method, the resulting F-tests are often called "exact" F-tests. The F-statistic was developed by Ronald Fisher in the 1920s as the variance ratio and was later named in his honor by George W. Snedecor. Common examples Common examples of the use of ''F''-tests include the study of the following cases * The hypothesis that the Arithme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
