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Redoxon Double Action Vitamin C Standard Tablets
Redoxon was the brand name of the first artificially synthesized ascorbic acid (vitamin C). Redoxon was first marketed to the general public by Hoffman-La Roche in 1934, making it the first mass-manufactured synthetic vitamin in history. The brand is now owned by German pharmaceutical company Bayer and is sold in many countries. History The product was developed by a team headed by chemist Tadeusz Reichstein, who discovered a method of synthesizing 30-40 grams of vitamin C from 100 grams of glucose. This used an intermediate step of creating sorbose using a bacterial fermentation method discovered by a French researcher, Gabriel Bertrand. In this method, fruit flies were attracted to a mixture of wine, vinegar, yeast bouillon, and sorbitol, a substance easily chemically prepared from glucose. Flies that fed upon sorbitol as a major food substrate excreted bacteria that were able to synthesize sorbose from sorbitol. The bacteria species was isolated, cultured and used in a fermen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sorbitol
Sorbitol (), less commonly known as glucitol (), is a sugar alcohol with a sweet taste which the human body metabolizes slowly. It can be obtained by reduction of glucose, which changes the converted aldehyde group (−CHO) to a primary alcohol group (−CH2OH). Most sorbitol is made from potato starch, but it is also found in nature, for example in apples, pears, peaches, and prunes. It is converted to fructose by sorbitol-6-phosphate 2-dehydrogenase. Sorbitol is an isomer of mannitol, another sugar alcohol; the two differ only in the orientation of the hydroxyl group on carbon 2.Kearsley, M. W.; Deis, R. C. Sorbitol and Mannitol. In Sweeteners and Sugar Alternatives in Food Technology; Ames: Oxford, 2006; pp 249-249-261. While similar, the two sugar alcohols have very different sources in nature, melting points, and uses. As an over-the-counter drug, sorbitol is used as a laxative to treat constipation. Synthesis Sorbitol may be synthesised via a glucose reduction r ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Effervescence (chemistry)
Effervescence is the escape of gas from an aqueous solution and the foaming or fizzing that results from that release. The word effervescence is derived from the Latin verb ''fervere'' (to boil), preceded by the adverb ''ex''. It has the same linguistic root as the word fermentation. Effervescence can also be observed when opening a bottle of champagne, beer or carbonated beverages such as some carbonated soft drinks. The visible bubbles are produced by the escape from solution of the dissolved gas (which itself is not visible while dissolved in the liquid). Although CO2 is most common for beverages, nitrogen gas is sometimes deliberately added to certain beers. The smaller bubble size creates a smoother beer head. Due to the poor solubility of nitrogen in beer, kegs or widgets are used for this. In the laboratory, a common example of effervescence is seen if hydrochloric acid is added to a block of limestone. If a few pieces of marble or an antacid tablet are put in hydrochl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Carbon Dioxide
Carbon dioxide ( chemical formula ) is a chemical compound made up of molecules that each have one carbon atom covalently double bonded to two oxygen atoms. It is found in the gas state at room temperature. In the air, carbon dioxide is transparent to visible light but absorbs infrared radiation, acting as a greenhouse gas. It is a trace gas in Earth's atmosphere at 421 parts per million (ppm), or about 0.04% by volume (as of May 2022), having risen from pre-industrial levels of 280 ppm. Burning fossil fuels is the primary cause of these increased CO2 concentrations and also the primary cause of climate change.IPCC (2022Summary for policy makersiClimate Change 2022: Mitigation of Climate Change. Contribution of Working Group III to the Sixth Assessment Report of the Intergovernmental Panel on Climate Change Cambridge University Press, Cambridge, United Kingdom and New York, NY, USA Carbon dioxide is soluble in water and is found in groundwater, lakes, i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Ascorbate
Sodium ascorbate is one of a number of mineral salts of ascorbic acid (vitamin C). The molecular formula of this chemical compound is C6H7NaO6. As the sodium salt of ascorbic acid, it is known as a mineral ascorbate. It has not been demonstrated to be more bioavailable than any other form of vitamin C supplement. Sodium ascorbate normally provides 131 mg of sodium per 1,000 mg of ascorbic acid (1,000 mg of sodium ascorbate contains 889 mg of ascorbic acid and 111 mg of sodium). As a food additive, it has the E number E301 and is used as an antioxidant and an acidity regulator. It is approved for use as a food additive in the EU, USA, Australia, and New Zealand. In ''in vitro'' studies, sodium ascorbate has been found to produce cytotoxic effects in various malignant cell lines, which include melanoma cells that are particularly susceptible. Production Sodium ascorbate is produced by dissolving ascorbic acid in water and adding an equivalent amount of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sodium Bicarbonate
Sodium bicarbonate (IUPAC name: sodium hydrogencarbonate), commonly known as baking soda or bicarbonate of soda, is a chemical compound with the formula NaHCO3. It is a salt (chemistry), salt composed of a sodium cation (Sodium, Na+) and a bicarbonate anion (Bicarbonate, HCO3−). Sodium bicarbonate is a white solid that is crystalline, but often appears as a fine powder. It has a slightly salty, alkaline taste resembling that of washing soda (sodium carbonate). The natural mineral form is nahcolite. It is a component of the mineral natron and is found dissolved in many mineral springs. Nomenclature Because it has long been known and widely used, the salt has many different names such as baking soda, bread soda, cooking soda, and bicarbonate of soda and can often be found near baking powder in stores. The term ''baking soda'' is more common in the United States, while ''bicarbonate of soda'' is more common in Australia, United Kingdom and Ireland. and in many northern/central ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Reichstein Process
The Reichstein process in chemistry is a combined chemical and microbial method for the production of ascorbic acid from D-glucose that takes place in several steps. This process was devised by Nobel Prize winner Tadeusz Reichstein and his colleagues in 1933 while working in the laboratory of the ETH in Zürich. Reaction steps The reaction steps are: * hydrogenation of D-glucose to D- sorbitol, an organic reaction with nickel as a catalyst under high temperature and high pressure. * Microbial oxidation or fermentation of sorbitol to L- sorbose with acetobacter at pH 4-6 and 30 °C. * protection of the 4 hydroxyl groups in sorbose by formation of the acetal with acetone and an acid to Diacetone-L-sorbose (2,3:4,6−Diisopropyliden−α−L−sorbose) * Organic oxidation with potassium permanganate (to Diprogulic acid) followed by heating with water gives the 2-Keto-L-gulonic acid * The final step is a ring-closing step or gamma lactonization with removal of water ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Capsicum
''Capsicum'' () is a genus of flowering plants in the nightshade family Solanaceae, native to the Americas, cultivated worldwide for their chili pepper or bell pepper fruit. Etymology and names The generic name may come from Latin , meaning 'box', presumably alluding to the pods; or possibly from the Greek word , 'to gulp'. The name "pepper" comes from the similarity of piquance (spiciness or "heat") of the flavor to that of black pepper, '' Piper nigrum'', although there is no botanical relationship with it or with Sichuan pepper. The original term, ''chilli'' (now ''chile'' in Mexico) came from the Nahuatl word ''chīlli'', denoting a larger ''Capsicum'' variety cultivated at least since 3000 BC, as evidenced by remains found in pottery from Puebla and Oaxaca. Different varieties were cultivated in South America, where they are known as ''ajíes'' (singular ''ají''), from the Quechua term for ''Capsicum''. The fruit (technically berries in the strict botanical ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Albert Szent-Györgyi
Albert Imre Szent-Györgyi de Nagyrápolt ( hu, nagyrápolti Szent-Györgyi Albert Imre; September 16, 1893 – October 22, 1986) was a Hungarian biochemist who won the Nobel Prize in Physiology or Medicine in 1937. He is credited with first isolating vitamin C and discovering the components and reactions of the citric acid cycle. He was also active in the Hungarian Resistance during World War II, and entered Hungarian politics after the war. Early life Szent-Györgyi was born in Budapest, Kingdom of Hungary in 1893. His father, Miklós Szent-Györgyi, was a landowner, born in Marosvásárhely, Transylvania (today Târgu Mureş, Romania), a Calvinist, and could trace his ancestry back to 1608 when Sámuel, a Calvinist predicant, was ennobled. At the time of Szent-Györgyi's birth, being of the nobility was considered important and created opportunities that otherwise were not available. (Miklós Szent-Györgyi's parents were Imre Szent-Györgyi and Mária Csiky). ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Elsevier
Elsevier () is a Dutch academic publishing company specializing in scientific, technical, and medical content. Its products include journals such as '' The Lancet'', '' Cell'', the ScienceDirect collection of electronic journals, '' Trends'', the '' Current Opinion'' series, the online citation database Scopus, the SciVal tool for measuring research performance, the ClinicalKey search engine for clinicians, and the ClinicalPath evidence-based cancer care service. Elsevier's products and services also include digital tools for data management, instruction, research analytics and assessment. Elsevier is part of the RELX Group (known until 2015 as Reed Elsevier), a publicly traded company. According to RELX reports, in 2021 Elsevier published more than 600,000 articles annually in over 2,700 journals; as of 2018 its archives contained over 17 million documents and 40,000 e-books, with over one billion annual downloads. Researchers have criticized Elsevier for its high profit ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the " vinegar fly" or " pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Redoxon Vita Guard Ace+ Vitamin C Standard Tablets
Redoxon was the brand name of the first artificially synthesized ascorbic acid (vitamin C). Redoxon was first marketed to the general public by Hoffman-La Roche in 1934, making it the first mass-manufactured synthetic vitamin in history. The brand is now owned by German pharmaceutical company Bayer and is sold in many countries. History The product was developed by a team headed by chemist Tadeusz Reichstein, who discovered a method of synthesizing 30-40 grams of vitamin C from 100 grams of glucose. This used an intermediate step of creating sorbose using a bacterial fermentation method discovered by a French researcher, Gabriel Bertrand. In this method, fruit flies were attracted to a mixture of wine, vinegar, yeast bouillon, and sorbitol, a substance easily chemically prepared from glucose. Flies that fed upon sorbitol as a major food substrate excreted bacteria that were able to synthesize sorbose from sorbitol. The bacteria species was isolated, cultured and used in a fermenta ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
