Redox Therapy
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Redox Therapy
Redox therapy is an experimental therapy that aims to effect an outcome by modifying the levels of pro-oxidant and antioxidant agents in cells. The term "redox" is a contraction of "reduction-oxidation". For cancer patients, the therapy is predicated on the idea that the redox state of cells may have an effect on cancer development. Historically, and in alternative medicine, the term "redox therapy" has also been used to describe the practice of administering high dosages of vitamins; in a 1984 study, high dosages of Menadione and Vitamin C were given to a patient. See also * Free-radical theory of aging#Antioxidant therapy, Antioxidant therapy * Orthomolecular medicine * Vitamin C megadosage References

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Pro-oxidant
Pro-oxidants are chemicals that induce oxidative stress, either by generating reactive oxygen species or by inhibiting antioxidant systems. The oxidative stress produced by these chemicals can damage cells and tissues, for example, an overdose of the analgesic paracetamol (acetaminophen) can fatally damage the liver, partly through its production of reactive oxygen species. Some substances can serve as either antioxidants or pro-oxidants, depending on conditions. Some of the important conditions include the concentration of the chemical and if oxygen or transition metals are present. While thermodynamically very favored, reduction of molecular oxygen or peroxide to superoxide or hydroxyl radical respectively is spin forbidden. This greatly reduces the rates of these reactions, thus allowing aerobic life to exist. As a result, the reduction of oxygen typically involves either the initial formation of singlet oxygen, or spin–orbit coupling through a reduction of a transition-se ...
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