Raphael M. Bonelli
Raphael M. Bonelli (born September 10, 1968 in Schärding in Austria) is an Austrian neuroscientist and psychiatrist. He graduated with a M.D. from Vienna University and with a Dr.med.sc. from the Medical University of Graz. He did postdoctoral research at Harvard Medical School, University of California, Los Angeles and Duke University. He is Faculty Scholar of the Duke University Center for Spirituality, Theology and Health. Bonelli is researcher on neuropsychiatry. His scientific interest is dementia, especially Huntington's disease. With his neuropsychiatric research group he described eight new treatment options for this disease: Pramipexol, Quetiapine, Minocycline, Mirtazapine, Zotepine, Ziprasidone, Venlafaxine and antipsychotic drug holidays in Huntington's disease. In a cooperation with Harold Koenig from Duke University he undertook the first systematic evidence based analysis on the connection between mental disorders and religion. The researchers conclude that there ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Vienna
The University of Vienna (german: Universität Wien) is a public research university located in Vienna, Austria. It was founded by Duke Rudolph IV in 1365 and is the oldest university in the German-speaking world. With its long and rich history, the university has developed into one of the largest universities in Europe, and also one of the most renowned, especially in the Humanities. It is associated with 21 Nobel prize winners and has been the academic home to many scholars of historical as well as of academic importance. History From the Middle Ages to the Enlightenment The university was founded on March 12, 1365, by Rudolf IV, Duke of Austria, hence the name "Alma Mater Rudolphina". After the Charles University in Prague and Jagiellonian University in Kraków, the University of Vienna is the third oldest university in Central Europe and the oldest university in the contemporary German-speaking world; it remains a question of definition as the Charles University ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Quetiapine
Quetiapine, sold under the brand name Seroquel among others, is an atypical antipsychotic medication used for the treatment of schizophrenia, bipolar disorder, and major depressive disorder. Despite being widely used as a sleep aid due to its sedating effect, the benefits of such use do not appear to generally outweigh the side effects. It is taken orally. Common side effects include sleepiness, constipation, weight gain, and dry mouth. Other side effects include low blood pressure with standing, seizures, a prolonged erection, high blood sugar, tardive dyskinesia, and neuroleptic malignant syndrome. In older people with dementia, its use increases the risk of death. Use in the third trimester of pregnancy may result in a movement disorder in the baby for some time after birth. Quetiapine is believed to work by blocking a number of receptors including serotonin and dopamine. Quetiapine was developed in 1985 and approved for medical use in the United States in 1997. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Evidence Based
Evidence-based medicine (EBM) is "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients". The aim of EBM is to integrate the experience of the clinician, the values of the patient, and the best available scientific information to guide decision-making about clinical management. The term was originally used to describe an approach to teaching the practice of medicine and improving decisions by individual physicians about individual patients. Background, history and definition Medicine has a long history of scientific inquiry about the prevention, diagnosis, and treatment of human disease. The concept of a controlled clinical trial was first described in 1662 by Jan Baptist van Helmont in reference to the practice of bloodletting. Wrote Van Helmont: The first published report describing the conduct and results of a controlled clinical trial was by James Lind, a Scottish naval surgeon who conducted rese ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Harold Koenig
Harold G. Koenig is a psychiatrist on the faculty of Duke University. His ideas have been covered in ''Newsweek'' and other news media with regard to religion, spirituality and health, a focus of some of his research and clinical practice. Templeton Foundation has provided great financial support to his activities. Education and academic career Koenig graduated with a B.S. in history from Stanford University (1974), later receiving his MD (1982) from University of California, San Francisco.Curriculum Vitae: Harold G. Koenig accessed 1 February 2010. He became Clinical Assistant Professor in Psychiatry (1992) and has been Professor of Psychiatry (2004-) at Duke University Medical Center. He ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Int Clin Psychopharmacol
''International Clinical Psychopharmacology'' is a bimonthly peer-reviewed medical journal published by Wolters Kluwer Health. It covers neuropsychopharmacology and clinical psychiatry. It was established in 1986. The editor-in-chief is Alessandro Serretti (University of Bologna). Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 2.023. References External links * Wolters Kluwer academic journals Pharmacology journals Psychiatry journals Bimonthly journals English-language journals Academic journals established in 1986 {{psychiatry-journal-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Venlafaxine
Venlafaxine, sold under the brand name Effexor among others, is an antidepressant medication of the serotonin-norepinephrine reuptake inhibitor (SNRI) class. It is used to treat major depressive disorder, generalized anxiety disorder, panic disorder, and social anxiety disorder. It may also be used for chronic pain. It is taken by mouth. It is also available as the salt venlafaxine besylate in an extended-release formulation (Venbysi XR). Common side effects include loss of appetite, constipation, dry mouth, dizziness, sweating, insomnia, drowsiness and sexual problems. Severe side effects include an increased risk of suicide, mania, and serotonin syndrome. Antidepressant withdrawal syndrome may occur if stopped. There are concerns that use during the later part of pregnancy can harm the baby. How it works is not entirely clear, but it seems to be related to the potentiation of the activity of some neurotransmitters in the brain. Venlafaxine was approved for medical use in ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Journal Of Psychopharmacology
The ''Journal of Psychopharmacology'' is a monthly peer-reviewed scientific journal published by Sage Publications on behalf of the British Association for Psychopharmacology. It was established in 1987 and is a member of the Committee on Publication Ethics. The editors-in-chief are David Nutt (Imperial College London) and Pierre Blier (University of Ottawa). The journal covers all aspects of psychopharmacology. Abstracting and indexing ''Journal of Psychopharmacology'' is abstracted and indexed in, among other databases: EMBASE/Excerpta Medica, MEDLINE, SCOPUS, and the Social Sciences Citation Index. According to the ''Journal Citation Reports'', the journal had a 2018 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 4.738, ranking it 30 out of 197 journals ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Ziprasidone
Ziprasidone, sold under the brand name Geodon among others, is an atypical antipsychotic used to treat schizophrenia and bipolar disorder. It may be used by mouth and by injection into a muscle (IM). The IM form may be used for acute agitation in people with schizophrenia. Common side effects include dizziness, drowsiness, dry mouth, and twitches. Although it can also cause weight gain, the risk is much lower than for other atypical antipsychotics. How it works is not entirely clear but is believed to involve effects on serotonin and dopamine in the brain. Ziprasidone was approved for medical use in the United States in 2001. The pills are made up of the hydrochloride salt, ziprasidone hydrochloride. The intramuscular form is the mesylate, ziprasidone mesylate trihydrate, and is provided as a lyophilized powder. In 2020, it was the 282nd most commonly prescribed medication in the United States, with more than 1million prescriptions. Medical uses Ziprasidone is approved ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Zotepine
Zotepine is an atypical antipsychotic drug indicated for acute and chronic schizophrenia. It has been used in Germany since 1990 (although it has been discontinued in Germany) and Japan since 1982. Zotepine is not approved for use in the United States, United Kingdom, Australia, Canada or New Zealand. Medical uses Zotepine's primary use is as a treatment for schizophrenia although clinical trials have been conducted (with positive results) into its efficacy as an antimanic agent in patients with acute bipolar mania. In a 2013 study in a comparison of 15 antipsychotic drugs in effectivity in treating schizophrenic symptoms, zotepine demonstrated medium-strong effectivity. Less effective than clozapine, slightly less effective than olanzapine and risperidone, approximately as effective as paliperidone, and slightly more effective than haloperidol, quetiapine, and aripiprazole. Side effects ; CommonBritish National Formulary 58. British Medical Association and Royal Pharmaceu ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Annals Of Pharmacotherapy
The ''Annals of Pharmacotherapy'' is a monthly peer-reviewed medical journal covering all aspects of pharmacotherapy. It was established in 1967 as ''Drug Intelligence''. The name changed a few times during its history, to ''Drug Intelligence & Clinical Pharmacy'' in 1969, and ''DICP: The Annals of Pharmacotherapy'' in 1989, before obtaining its current name in 1992. According to the ''Journal Citation Reports'', the journal has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as ... of 3.154. References External links * Pharmacotherapy journals Monthly journals English-language journals Publications established in 1967 SAGE Publishing academic journals {{pharma-journal-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mirtazapine
Mirtazapine, sold under the brand name Remeron amongst others, is an atypical antidepressant, and as such is used primarily to treat depression. Its effects may take up to four weeks, but can also manifest as early as one to two weeks. It is often used in cases of depression complicated by anxiety or insomnia. The effectiveness of mirtazapine is comparable to other commonly prescribed antidepressants. It is taken by mouth. Common side effects include sleepiness, dizziness, increased appetite and weight gain. Serious side effects may include mania, low white blood cell count, and increased suicide among children. Withdrawal symptoms may occur with stopping. It is not recommended together with a monoamine oxidase inhibitor, although evidence supporting the danger of this combination has been refuted. It is unclear if use during pregnancy is safe. How it works is not clear, but it may involve blocking certain adrenergic and serotonin receptors. Chemically, it is a tetrac ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |