Ralf F. W. Bartenschlager
Ralf F. W. Bartenschlager (born 29 May 1958) is a German virologist who has been researching hepatitis C since 1989. He is a professor in the Department of Infectious Diseases at the Heidelberg University. Early life Bartenschlager grew up in Mannheim. After high school, he worked as a policemen for four years before starting his undergraduate in biology in 1981 at Heidelberg University. He conduced his thesis work with Heinz Schaller at the ZMBH in Heidelberg on the structure and functional role of the P-protein in Hepatitis B viruses. After graduating in 1990, he continued working as a postdoc at Heidelberg University until joining Hoffmann-La Roche in 1991, where he began working on Hepatitis C. Other activities * Robert Koch Institute (RKI), Member of the Scientific Advisory Board * Wilhelm Sander Foundation, Member of the Scientific Advisory Board Recognition Bartenschlager was a recipient of the 2016 Lasker Award for Clinical Research for discoveries related to hepat ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Mannheim
Mannheim (; Palatine German language, Palatine German: or ), officially the University City of Mannheim (), is the List of cities in Baden-Württemberg by population, second-largest city in Baden-Württemberg after Stuttgart, the States of Germany, state capital, and Germany's List of cities in Germany by population, 21st-largest city, with a population of over 315,000. It is located at the border with Rhineland-Palatinate. The city is the cultural and economic centre of the Rhine-Neckar, Germany's Metropolitan regions in Germany, seventh-largest metropolitan region, with nearly 2.4 million inhabitants. Mannheim is located at the confluence of the Upper Rhine and the Neckar in the Kurpfalz (region), Kurpfalz (Electoral Palatinate) region of northwestern Baden-Württemberg. The city lies in the Upper Rhine Plain, Germany's warmest region, between the Palatine Forest and the Oden Forest. Mannheim forms a continuous urban zone of around 500,000 inhabitants with Ludwigshafen am Rhe ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Heidelberg
Heidelberg University, officially the Ruprecht Karl University of Heidelberg (; ), is a public university, public research university in Heidelberg, Baden-Württemberg, Germany. Founded in 1386 on instruction of Pope Urban VI, Heidelberg is List of universities in Germany#Universities by date of establishment, Germany's oldest university and one of the List of oldest universities in continuous operation, world's oldest surviving universities; it was the third university established in the Holy Roman Empire after Charles University, Prague (1347) and University of Vienna, Vienna (1365). Since 1899, it has been a coeducational institution. Heidelberg is one of the most prestigious universities in Germany. It is a German Excellence Universities, German Excellence University, part of the U15 (German universities), U15, as well as a founding member of the League of European Research Universities and the Coimbra Group. The university consists of twelve Faculty (division), faculties and ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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University Of Mainz
The Johannes Gutenberg University Mainz () is a public research university in Mainz, Rhineland Palatinate, Germany. It has been named after the printer Johannes Gutenberg since 1946. it had approximately 32,000 students enrolled in around 100 academic programs. The university is organized into 11 faculties. The university is a member of the German U15, a group of fifteen major research and medical universities in Germany. It also participates in the IT-Cluster Rhine-Main-Neckar and forms part of the Rhine-Main-Universities (RMU) along with Goethe University Frankfurt and Technische Universität Darmstadt. Founded in 1477, it is one of the oldest universities in Europe and one of the most prestigious in Germany. Faculties The Johannes Gutenberg University Mainz is divided in ten faculties since 07 April 2024. * Faculty of Catholic and Protestant Theology * Faculty of Social Sciences, Media, and Sports * Faculty of Law, Management, and Economics * University Medicine * Fa ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hepatitis C
Hepatitis C is an infectious disease caused by the hepatitis C virus (HCV) that primarily affects the liver; it is a type of viral hepatitis. During the initial infection period, people often have mild or no symptoms. Early symptoms can include fever, dark urine, abdominal pain, and jaundice, yellow tinged skin. The virus persists in the liver, becoming Chronic condition, chronic, in about 70% of those initially infected. Early on, chronic infection typically has no symptoms. Over many years however, it often leads to liver disease and occasionally cirrhosis. In some cases, those with cirrhosis will develop serious complications such as liver failure, hepatocellular carcinoma, liver cancer, or esophageal varices, dilated blood vessels in the esophagus and gastric varices, stomach. HCV is spread primarily by blood-to-blood contact associated with injection drug use, poorly sterilized medical equipment, needlestick injuries in healthcare, and blood transfusions, transfusions. In r ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Heidelberg University
Heidelberg University, officially the Ruprecht Karl University of Heidelberg (; ), is a public research university in Heidelberg, Baden-Württemberg, Germany. Founded in 1386 on instruction of Pope Urban VI, Heidelberg is Germany's oldest university and one of the world's oldest surviving universities; it was the third university established in the Holy Roman Empire after Prague (1347) and Vienna (1365). Since 1899, it has been a coeducational institution. Heidelberg is one of the most prestigious universities in Germany. It is a German Excellence University, part of the U15, as well as a founding member of the League of European Research Universities and the Coimbra Group. The university consists of twelve faculties and offers degree programmes at undergraduate, graduate and postdoctoral levels in some 100 disciplines. The language of instruction is usually German, while a considerable number of graduate degrees are offered in English as well as some in French. 57 Nobel ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hoffmann-La Roche
F. Hoffmann-La Roche AG, commonly known as Roche (), is a Swiss multinational holding healthcare company that operates worldwide under two divisions: Pharmaceuticals and Diagnostics. Its holding company, Roche Holding AG, has shares listed on the SIX Swiss Exchange. The company headquarters are located in Basel. Roche is the fifth-largest pharmaceutical company in the world by revenue and the leading provider of cancer treatments globally. In 2023, the company’s seat in Forbes Global 2000 was 76. The company owns the American biotechnology company Genentech, which is a wholly owned independent subsidiary, and the Japanese biotechnology company Chugai Pharmaceuticals, as well as the United States–based companies Ventana and Foundation Medicine. Roche's revenues during fiscal year 2020, were 58.32 billion Swiss francs. Descendants of the founding Hoffmann and Oeri families own slightly over half of the bearer shares with voting rights (a pool of family shareholders 45%, ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Robert Koch Institute
The Robert Koch Institute (RKI) is a German federal government agency and research institute responsible for disease control and prevention. It is located in Berlin and Wernigerode. As an upper federal agency, it is subordinate to the Federal Ministry of Health. It was founded in 1891 and is named for its founding director, the founder of modern bacteriology and Nobel laureate Robert Koch. Tasks The Robert Koch Institute monitors public health. Its core tasks include the detection, prevention and combatting of infectious diseases and non-communicable diseases in Germany. The institute advises the specialist public and government, e.g. on preventing and tackling infectious disease outbreaks such as the COVID-19 pandemic, the swine flu pandemic in 2009 and the EHEC O104:H4 outbreak in 2011. The institute is also in charge of health monitoring and health reporting in Germany, covering non-communicable diseases: in large monitoring studies, RKI monitors the health status of ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Lasker Award
In 1945 Albert Lasker and Mary Woodard Lasker created the Lasker Awards. Every year since then the award has been given to the living person considered to have made the greatest contribution to medical science or who has demonstrated public service on behalf of medicine. They are administered by the Lasker Foundation. The Lasker is sometimes referred to as "America's Nobels". The Lasker Awards have gained a reputation for identifying future winners of the Nobel Prize. Eighty-six Lasker laureates have received the Nobel Prize, including 32 in the last two decades. Claire Pomeroy is the current president of the Lasker Foundation. Award The award is given in four branches of medical science: # Albert Lasker Basic Medical Research Award # Lasker–DeBakey Clinical Medical Research Award # Lasker–Bloomberg Public Service Award (Renamed in 2011 from Mary Woodard Lasker Public Service Award. Renamed in 2000 from Albert Lasker Public Service Award.) # '' Lasker–Koshland Speci ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Hepatitis C Virus
The hepatitis C virus (HCV) is a small (55–65 nm in size), enveloped, positive-sense single-stranded RNA virus of the family ''Flaviviridae''. The hepatitis C virus is the cause of hepatitis C and some cancers such as liver cancer ( hepatocellular carcinoma, abbreviated HCC) and lymphomas in humans. Taxonomy The hepatitis C virus belongs to the genus '' Hepacivirus'', a member of the family ''Flaviviridae''. Before 2011, it was considered to be the only member of this genus. However a member of this genus has been discovered in dogs: canine hepacivirus. There is also at least one virus in this genus that infects horses. Several additional viruses in the genus have been described in bats and rodents. Structure The hepatitis C virus particle consists of a lipid membrane envelope that is 55 to 65 nm in diameter. Two viral envelope glycoproteins, E1 and E2, are embedded in the lipid envelope. They take part in viral attachment and entry into the cell. Within the e ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Charles M
Charles is a masculine given name predominantly found in English and French speaking countries. It is from the French form ''Charles'' of the Proto-Germanic name (in runic alphabet) or ''*karilaz'' (in Latin alphabet), whose meaning was "free man". The Old English descendant of this word was '' Ċearl'' or ''Ċeorl'', as the name of King Cearl of Mercia, that disappeared after the Norman conquest of England. The name was notably borne by Charlemagne (Charles the Great), and was at the time Latinized as ''Karolus'' (as in ''Vita Karoli Magni''), later also as '' Carolus''. Etymology The name's etymology is a Common Germanic noun ''*karilaz'' meaning "free man", which survives in English as churl (James (wikt:Appendix:Proto-Indo-European/ǵerh₂-">ĝer-, where the ĝ is a palatal consonant, meaning "to rub; to be old; grain." An old man has been worn away and is now grey with age. In some Slavic languages, the name ''Drago (given name), Drago'' (and variants: ''Drago ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Michael J
Michael may refer to: People * Michael (given name), a given name * he He ..., a given name * Michael (surname), including a list of people with the surname Michael Given name * Michael (bishop elect)">Michael (surname)">he He ..., a given name * Michael (surname), including a list of people with the surname Michael Given name * Michael (bishop elect), English 13th-century Bishop of Hereford elect * Michael (Khoroshy) (1885–1977), cleric of the Ukrainian Orthodox Church of Canada * Michael Donnellan (fashion designer), Michael Donnellan (1915–1985), Irish-born London fashion designer, often referred to simply as "Michael" * Michael (footballer, born 1982), Brazilian footballer * Michael (footballer, born 1983), Brazilian footballer * Michael (footballer, born 1993), Brazilian footballer * Michael (footballer, born February 1996), Brazilian footballer * Michael (footballer, born March 1996), Brazilian footballer * Michael (footballer, born 1999), Brazilian football ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Beijerinck Virology Prize
The M.W. Beijerinck Virology Prize (''M.W. Beijerinck Virologie Prijs'') is a prize in virology awarded every two years by the ''Koninklijke Nederlandse Akademie van Wetenschappen'' (KNAW). The prize consists of a medal and a monetary award of €35,000. KNAW's two conditions for the prize nomination are that the nominee must be an internationally recognized researcher who has "made a groundbreaking contribution to research in the field of virology in the broadest sense" and must have an appointment at a university or research institute. The prize is named in honor of the Dutch microbiologist Martinus Willem Beijerinck. KNAW appoints an advisory committee which gives advice to KNAW concerning the prize nominees. KNAW has regulations for who may submit nominations. Before 2014 the prize was awarded every three years. Prize winners *1966 Egbertus van Slogteren, Netherlands *1969 , United States *1972 W. Berends, Netherlands *1975 E.M.J. Jaspars and A. van Kammen, Netherlands * ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |