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RAB11FIP3
Rab11 family-interacting protein 3 is a protein that in humans is encoded by the ''RAB11FIP3'' gene. Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001). upplied by OMIMref name="entrez" /> Interactions RAB11FIP3 has been shown to interact with RAB11A Ras-related protein Rab-11A is a protein that in humans is encoded by the ''RAB11A'' gene. Function The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated se .... References Further reading * * * * * * * * * * * * * * * EF-hand-containing proteins {{Gene-16-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RAB11A
Ras-related protein Rab-11A is a protein that in humans is encoded by the ''RAB11A'' gene. Function The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory pathways, and may be involved in protein transport. Rab-11a controls intracellular trafficking of the innate immune receptor TLR4, and thereby also receptor signaling Interactions RAB11A has been shown to interact with: * RAB11FIP1, * RAB11FIP2, * RAB11FIP3, * RAB11FIP4, and * RAB11FIP5 *Moesin Moesin is a protein that in humans is encoded by the ''MSN'' gene. Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin. ERM proteins appear to function as cross-linkers ... References Further reading * * * * * * * * * * * * * * * * * {{PDB Gallery, geneid=8766 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Rab GTPase
The Rab family of proteins is a member of the Ras superfamily of small G proteins. Approximately 70 types of Rabs have now been identified in humans. Rab proteins generally possess a GTPase fold, which consists of a six-stranded beta sheet which is flanked by five alpha helices. Rab GTPases regulate many steps of membrane trafficking, including vesicle formation, vesicle movement along actin and tubulin networks, and membrane fusion. These processes make up the route through which cell surface proteins are trafficked from the Golgi to the plasma membrane and are recycled. Surface protein recycling returns proteins to the surface whose function involves carrying another protein or substance inside the cell, such as the transferrin receptor, or serves as a means of regulating the number of a certain type of protein molecules on the surface. Function Rab proteins are peripheral membrane proteins, anchored to a membrane via a lipid group covalently linked to an amino acid. Speci ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RAB1A
Ras-related protein Rab-1A is a protein that in humans is encoded by the ''RAB1A'' gene. Interactions RAB1A has been shown to interact with: * CHML, * GOLGA2, * GOLGA5, * MICAL1 NEDD9-interacting protein with calponin homology and LIM domains is a protein that in humans is encoded by the ''MICAL1'' gene. Interactions MICAL1 has been shown to Protein-protein interaction, interact with NEDD9 and RAB1A. References Furthe ... * RABAC1, and * CHM. References Further reading * * * * * * * * * * * * * * * * * * {{PDB Gallery, geneid=5861 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
