Psychedelic-assisted Therapy
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Psychedelic-assisted Therapy
Psychedelic therapy (or psychedelic-assisted therapy) refers to the proposed use of psychedelic drugs, such as psilocybin, ayahuasca, LSD, psilocin, mescaline (peyote), DMT, 5-MeO-DMT, Ibogaine, MDMA, to treat mental disorders. As of 2021, psychedelic drugs are controlled substances in most countries and psychedelic therapy is not legally available outside clinical trials, with some exceptions. The procedure for psychedelic therapy differs from that of therapies using conventional psychiatric medications. While conventional medications are usually taken without supervision at least once daily, in contemporary psychedelic therapy the drug is administered in a single session (or sometimes up to three sessions) in a therapeutic context. The therapeutic team prepares the patient for the experience beforehand and helps them integrate insights from the drug experience afterwards. After ingesting the drug, the patient normally wears eyeshades and listens to music to facilitate focus on t ...
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Psychedelic Drug
Psychedelics are a subclass of hallucinogenic drugs whose primary effect is to trigger non-ordinary mental states (known as psychedelic experiences or "trips") and a perceived "expansion of consciousness". Also referred to as classic hallucinogens or serotonergic hallucinogens, the term ''psychedelic'' is sometimes used more broadly to include various other types of hallucinogens as well, such as those which are atypical or adjacent to psychedelia like salvia and MDMA, respectively. Classic psychedelics generally cause specific psychological, visual, and auditory changes, and oftentimes a substantially altered state of consciousness. They have had the largest influence on science and culture, and include mescaline, LSD, psilocybin, and DMT. There are a large number of both naturally occurring and synthetic serotonergic psychedelics. Most psychedelic drugs fall into one of the three families of chemical compounds: tryptamines, phenethylamines, or lysergamides. T ...
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Anxiety
Anxiety is an emotion characterised by an unpleasant state of inner wikt:turmoil, turmoil and includes feelings of dread over Anticipation, anticipated events. Anxiety is different from fear in that fear is defined as the emotional response to a present threat, whereas anxiety is the anticipation of a future one. It is often accompanied by nervous behavior such as pacing back and forth, Somatic anxiety, somatic complaints, and Rumination (psychology), rumination. Anxiety is a feeling of uneasiness and worry, usually generalized and unfocused as an overreaction to a situation that is only subjectively seen as menacing. It is often accompanied by muscular tension, restlessness, Fatigue (medical), fatigue, inability to catch one's breath, tightness in the abdominal region, nausea, and problems in concentration. Anxiety is closely related to fear, which is a response to a real or perceived immediate threat (fight-or-flight response); anxiety involves the expectation of a future t ...
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Langley Porter Psychiatric Institute
Langley Porter Psychiatric Hospital (LPPH) is a psychiatric teaching hospital, part of the Psychiatry Department at the University of California, San Francisco. It was located on the Parnassus campus of UCSF until 2023, when it moved to the UCSF Medical Center at Mount Zion. Langley Porter Clinic was the first psychiatric institute in California, and is the oldest facility of the UCSF Psychiatry Department. History The foundation stone of the hospital was laid in 1941. The hospital opened in 1942 with 100 beds, and was completed in 1943. The hospital was first known by the name "Langley Porter Clinic", which later changed to the "Langley Porter Neuropsychiatric Institute", and later again to "Langley Porter Psychiatric Institute", or informally, "LPPI". In 1948, "the clinic's director, Karl Bowman, was transforming it into one of the world's most important hubs for research into transgender sexual identities." It was also "an important early center for the development of psyche ...
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Sandoz Laboratories
Novartis AG is a Swiss multinational corporation, multinational pharmaceutical company, pharmaceutical corporation based in Basel, Switzerland. Novartis is one of the largest pharmaceutical companies in the world and was the eighth largest by revenue in 2024. Novartis manufactures the drugs clozapine (Clozaril), diclofenac (Voltaren; sold to GlaxoSmithKline in 2015 deal), carbamazepine (Tegretol), valsartan (Diovan), imatinib mesylate (Gleevec/Glivec), cyclosporine (Neoral/Sandimmune), letrozole (Femara), methylphenidate (Ritalin; produced by Sandoz since 2023), terbinafine (Lamisil), deferasirox (Exjade), and others. Novartis was formed in 1996 by the merger of Ciba-Geigy and Sandoz. It was considered the largest corporate merger in history during that time. The pharmaceutical and agrochemical divisions of both companies formed Novartis as an independent entity. The name Novartis was based on the Latin terms, ''novae artes'' (new skills). After the merger, other Ciba-Geigy and ...
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Albert Hofmann
Albert Hofmann (11 January 1906 – 29 April 2008) was a Swiss chemist known for being the first to synthesize, ingest, and learn of the psychedelic effects of lysergic acid diethylamide (LSD). Hofmann's team also isolated, named and synthesized the principal psychedelic mushroom compounds psilocybin and psilocin. He authored more than 100 scientific articles and numerous books, including ''LSD: Mein Sorgenkind'' (''LSD: My Problem Child''). In 2007, he shared first place with Tim Berners-Lee on a list of the 100 greatest living geniuses published by ''The Daily Telegraph'' newspaper. Early life and education Albert Hofmann was born in Baden, Switzerland, on 11 January 1906. He was the first of four children to factory toolmaker Adolf Hofmann and Elisabeth ( Schenk) and was baptized Protestant. When his father became ill, Hofmann obtained a position as a commercial apprentice in concurrence with his studies. Owing to his father's low income, Albert's godfather paid for his e ...
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Culture
Culture ( ) is a concept that encompasses the social behavior, institutions, and Social norm, norms found in human societies, as well as the knowledge, beliefs, arts, laws, Social norm, customs, capabilities, Attitude (psychology), attitudes, and habits of the individuals in these groups.Tylor, Edward. (1871). ''Primitive Culture''. Vol 1. New York: J. P. Putnam's Son Culture often originates from or is attributed to a specific region or location. Humans acquire culture through the learning processes of enculturation and socialization, which is shown by the diversity of cultures across societies. A cultural norm codifies acceptable conduct in society; it serves as a guideline for behavior, dress, language, and demeanor in a situation, which serves as a template for expectations in a social group. Accepting only a monoculturalism, monoculture in a social group can bear risks, just as a single species can wither in the face of environmental change, for lack of functional respo ...
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Ritual
A ritual is a repeated, structured sequence of actions or behaviors that alters the internal or external state of an individual, group, or environment, regardless of conscious understanding, emotional context, or symbolic meaning. Traditionally associated with gestures, words, or revered objects, rituals also occur in non-human species, such as elephant mourning or corvid object-leaving. They may be prescribed by tradition, including religious practices, and are often characterized by formalism, traditionalism, rule-governance, and performance. Rituals are a feature of all known human societies. They include not only the worship rites and sacraments of organized religions and cults, but also rites of passage, atonement and ritual purification, purification rites, oaths of allegiance, dedication ceremonies, coronations and presidential inaugurations, marriages, funerals and more. Even common actions like handshake, hand-shaking and saying "hello" may be termed as ''rituals''. Th ...
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Spirituality
The meaning of ''spirituality'' has developed and expanded over time, and various meanings can be found alongside each other. Traditionally, spirituality referred to a religious process of re-formation which "aims to recover the original shape of man", oriented at "the image of God" as exemplified by the List of founders of religious traditions, founders and sacred texts of the religions of the world. The term was used within early Christianity to refer to a life oriented toward Holy Spirit (Christianity), the Holy Spirit and broadened during the Late Middle Ages to include mind, mental aspects of life. In modern times, the term both spread to other religious traditions and broadened to refer to a wider range of experiences, including a range of Western esotericism, esoteric and religious traditions. Modern usages tend to refer to a subjective experience of a Sacredness, sacred dimension, and the "deepest values and meanings by which people live", often in a context separate from ...
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Medicine Man
A medicine man (from Ojibwe ''mashkikiiwinini'') or medicine woman (from Ojibwe ''mashkikiiwininiikwe'') is a traditional healer and spiritual leader who serves a community of Indigenous people of the Americas. Each culture has its own name in its language for spiritual healers and ceremonial leaders. Cultural context In the ceremonial context of Indigenous North American communities, "medicine" usually refers to spiritual healing. Medicine people use many practices, including specialized knowledge of Native American ethnobotany. Herbal healing is a common practice in many Indigenous households of the Americas;Alcoze, Dr Thomas M. Ethnobotany from a Native American Perspective: Restoring Our Relationship with the Earth" in '' Botanic Gardens Conservation International'' Volume 1 Number 19 - December 1999Northeastern Area State and Private Forestry,Traditional Ecological Knowledge: Sustaining Our Lives and the Natural World at ''United States Department of Agriculture, F ...
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Shamanism
Shamanism is a spiritual practice that involves a practitioner (shaman) interacting with the spirit world through altered states of consciousness, such as trance. The goal of this is usually to direct spirits or spiritual energies into the physical world for the purpose of healing, divination, or to aid human beings in some other way. Beliefs and practices categorized as shamanic have attracted the interest of scholars from a variety of disciplines, including anthropologists, archeologists, historians, religious studies scholars, philosophers, and psychologists. Hundreds of books and academic papers on the subject have been produced, with a peer-reviewed academic journal being devoted to the study of shamanism. Terminology Etymology The Modern English word ''shamanism'' derives from the Russian word , , which itself comes from the word from a Tungusic language – possibly from the southwestern dialect of the Evenki spoken by the Sym Evenki peoples, or from the ...
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Breakthrough Therapy
Breakthrough therapy is a United States Food and Drug Administration designation that expedites drug development that was created by Congress under Section 902 of the 9 July 2012 Food and Drug Administration Safety and Innovation Act. The FDA's "breakthrough therapy" designation is not intended to imply that a drug is actually a "breakthrough" or that there is high-quality evidence of treatment efficacy for a particular condition; rather, it allows the FDA to grant priority review to drug candidates if preliminary clinical trials indicate that the therapy may offer substantial treatment advantages over existing options for patients with serious or life-threatening diseases. The FDA has other mechanisms for expediting the review and approval process for promising drugs, including fast track designation, accelerated approval, and priority review. Requirements A breakthrough therapy designation can be assigned to a drug if "it is a drug which is intended alone or in combination wit ...
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Food And Drug Administration
The United States Food and Drug Administration (FDA or US FDA) is a List of United States federal agencies, federal agency of the United States Department of Health and Human Services, Department of Health and Human Services. The FDA is responsible for protecting and promoting public health through the control and supervision of food safety, tobacco products, caffeine products, dietary supplements, Prescription drug, prescription and Over-the-counter drug, over-the-counter pharmaceutical drugs (medications), vaccines, biopharmaceuticals, blood transfusions, medical devices, electromagnetic radiation emitting devices (ERED), cosmetics, Animal feed, animal foods & feed and Veterinary medicine, veterinary products. The FDA's primary focus is enforcement of the Federal Food, Drug, and Cosmetic Act (FD&C). However, the agency also enforces other laws, notably Section 361 of the Public Health Service Act as well as associated regulations. Much of this regulatory-enforcement work is ...
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