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Psilocybe Cyanescens
''Psilocybe cyanescens'', commonly known as the wavy cap or potent psilocybe, is a species of potent psychedelic mushroom. The main compounds responsible for its psychedelic effects are psilocybin and psilocin. It belongs to the family Hymenogastraceae. A formal description of the species was published by Elsie Wakefield in 1946 in the ''Transactions of the British Mycological Society'', based on a specimen she had recently collected at Kew Gardens. She had begun collecting the species as early as 1910. The mushroom is not generally regarded as being physically dangerous to adults. Since all the psychoactive compounds in ''P. cyanescens'' are Aqueous solution, water-soluble, the fruiting bodies can be rendered non-psychoactive through parboiling, allowing their culinary use. However, since most people find them overly bitter and they are too small to have great nutritive value, this is not frequently done. ''Psilocybe cyanescens'' can sometimes fruit in colossal quantities; ...
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Elsie Maud Wakefield
Elsie Maud Wakefield, OBE (3 July 1886 – 17 June 1972) was an England, English mycology, mycologist and plant pathology, plant pathologist. Background and education She was born in Birmingham, the daughter of a science teacher. She was educated at Swansea High School for Girls and then went to Somerville College, Oxford, where she received a first class honours degree in botany. Career in mycology After completing her degree, Wakefield was awarded a Gilchrist scholarship and worked with Prof. Karl von Tubeuf in Munich, where she undertook cultural studies on the larger fungi, publishing her first paper there, in German. On her return in 1910, she became assistant to George Edward Massee, George Massee, head of mycology and cryptogams at the Royal Botanic Gardens, Kew. On his retirement in 1915, she took over his position as head of mycology. In 1920, she took advantage of a travelling scholarship from Somerville College to spend six months working as a mycologist in the West ...
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Epitype
A holotype (Latin: ''holotypus'') is a single physical example (or illustration) of an organism used when the species (or lower-ranked taxon) was formally described. It is either the single such physical example (or illustration) or one of several examples, but explicitly designated as the holotype. Under the International Code of Zoological Nomenclature (ICZN), a holotype is one of several kinds of name-bearing types. In the International Code of Nomenclature for algae, fungi, and plants (ICN) and ICZN, the definitions of types are similar in intent but not identical in terminology or underlying concept. For example, the holotype for the butterfly '' Plebejus idas longinus'' is a preserved specimen of that subspecies, held by the Museum of Comparative Zoology at Harvard University. In botany and mycology, an isotype is a duplicate of the holotype, generally pieces from the same individual plant or samples from the same genetic individual. A holotype is not necessarily "typi ...
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Baeocystin
Baeocystin, also known as norpsilocybin or 4-phosphoryloxy-''N''-methyltryptamine (4-PO-NMT), is a zwitterionic alkaloid and analogue of psilocybin. It is found as a minor compound in most psilocybin mushrooms together with psilocybin, norbaeocystin, aeruginascin, and psilocin. Baeocystin is the ''N''-demethylated derivative of psilocybin and the 4-phosphorylated derivative of 4-HO-NMT (4-hydroxy- ''N''-methyltryptamine). The structures at right illustrate baeocystin in its zwitterionic form. History Baeocystin was first isolated from the mushroom '' Psilocybe baeocystis'', and later from '' P. semilanceata'', '' Panaeolus renenosus'', '' Panaeolus subbalteatus'', and ''Copelandia chlorocystis''. It was first synthesized by Troxler ''et al''. in 1959. Pharmacology Baeocystin is thought to be a prodrug of norpsilocin, analogously to how psilocybin is a prodrug of psilocin. Norpsilocin is a potent and centrally penetrant agonist of the serotonin 5-HT2A receptor and a ...
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Indole Alkaloid
Indole alkaloids are a class of alkaloids containing a structural moiety of indole; many indole alkaloids also include isoprene groups and are thus called terpene indole or secologanin tryptamine alkaloids. Containing more than 4100 known different compounds, it is one of the largest classes of alkaloids. Many of them possess significant physiological activity and some of them are used in medicine. The amino acid tryptophan is the biochemical precursor of indole alkaloids. History The action of some indole alkaloids has been known for ages. Aztecs used the psilocybin mushrooms which contain alkaloids psilocybin and psilocin. The flowering plant ''Rauvolfia serpentina'' which contains reserpine was a common medicine in India around 1000 BC. Africans used the roots of the perennial rainforest shrub Iboga, which contain ibogaine, as a stimulant. An infusion of Calabar bean seeds was given to people accused of crime in Nigeria: its rejection by stomach was regarded as a sign of ...
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Ten Speed Press
Ten Speed Press is a publishing house founded in Berkeley, California, in 1971 by Phil Wood. It was bought by Random House in February 2009 and became part of their Crown Publishing Group division. History Wood worked with Barnes & Noble in 1962, Penguin Books in 1965, and had a senior sales position at Penguin Books in Baltimore and New York before founding Ten Speed Press. Wood died of cancer in December 2010. Ten Speed's first book was ''Anybody's Bike Book'', which is still in print. It inspired the publisher's name and has sold more than a million copies. Ten Speed's all-time best-seller is '' What Color is Your Parachute? A Practical Manual for Job-Hunters and Career-Changers'' by Richard N. Bolles (1972). It has been reissued in new editions and, as of 2009, has sold more than ten million copies, translated into 20 languages. Ten Speed has published numerous other non-fiction titles, including '' Moosewood Cookbook'', '' White Trash Cooking,'' '' Why Cats Paint,'' ''Th ...
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Central Europe
Central Europe is a geographical region of Europe between Eastern Europe, Eastern, Southern Europe, Southern, Western Europe, Western and Northern Europe, Northern Europe. Central Europe is known for its cultural diversity; however, countries in this region also share some historical and cultural similarities. The region is variously defined, but it’s minimum definition could be considered of consisting of Austria, Bosnia and Herzegovina, Croatia, the Czech Republic, eastern France, Germany, Liechtenstein, Luxembourg, Poland, Slovakia, Slovenia and Switzerland. But also the Baltic States, the Alsace in north-east France, and South Tyrol, northern Belluno , and Friuli-Venezia Giulia in north-east Italy are culturally usually considered to be part of Central Europe. From the early 16th century until the early 18th century, parts of Croatia and Hungary were ruled by the Ottoman Empire. During the 17th century, the empire also occupied southern parts of present-day Slovakia. During ...
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Western Europe
Western Europe is the western region of Europe. The region's extent varies depending on context. The concept of "the West" appeared in Europe in juxtaposition to "the East" and originally applied to the Western half of the ancient Mediterranean world, the Latin West of the Roman Empire, and "Western Christendom". Beginning with the Renaissance and the Age of Discovery, roughly from the 15th century, the concept of ''Europe'' as "the Western world, West" slowly became distinguished from and eventually replaced the dominant use of "Christendom" as the preferred endonym within the area. By the Age of Enlightenment and the Industrial Revolution, the concepts of "Eastern Europe" and "Western Europe" were more regularly used. The distinctiveness of Western Europe became most apparent during the Cold War, when Europe was divided for 40 years by the Iron Curtain into the Western Bloc and Eastern Bloc, each characterised by distinct political and economical systems. Historical divisions ...
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San Francisco Bay Area
The San Francisco Bay Area, commonly known as the Bay Area, is a List of regions of California, region of California surrounding and including San Francisco Bay, and anchored by the cities of Oakland, San Francisco, and San Jose, California, San Jose. The Association of Bay Area Governments defines the Bay Area as including the nine counties that border the estuary, estuaries of San Francisco Bay, San Pablo Bay, and Suisun Bay: Alameda County, California, Alameda, Contra Costa County, California, Contra Costa, Marin County, California, Marin, Napa County, California, Napa, San Mateo County, California, San Mateo, Santa Clara County, California, Santa Clara, Solano County, California, Solano, Sonoma County, California, Sonoma, and San Francisco County, California, San Francisco. Other definitions may be either smaller or larger, and may include neighboring counties which are not officially part of the San Francisco Bay Area, such as the Central Coast (California), Central Coast c ...
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Pacific Northwest
The Pacific Northwest (PNW; ) is a geographic region in Western North America bounded by its coastal waters of the Pacific Ocean to the west and, loosely, by the Rocky Mountains to the east. Though no official boundary exists, the most common conception includes the U.S. states of Oregon, Washington (state), Washington, Idaho, and the Canadian province of British Columbia. Some broader conceptions reach north into Alaska and Yukon, south into Northern California, and east into western Montana. Other conceptions may be limited to the coastal areas west of the Cascade Mountains, Cascade and Coast Mountains, Coast mountains. The Northwest Coast is the coastal region of the Pacific Northwest, and the Northwest Plateau (also commonly known as "British Columbia Interior, the Interior" in British Columbia), is the inland region. The term "Pacific Northwest" should not be confused with the Northwest Territory (also known as the Great Northwest, a historical term in the United States) ...
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Psilocybe Cyanescens Range-map
''Psilocybe'' ( ) is a genus of gilled mushrooms, growing worldwide, in the family Hymenogastraceae. Many species contain the psychedelic compounds psilocybin and psilocin. Taxonomy Taxonomic history A 2002 study of the molecular phylogeny of the agarics indicated the genus ''Psilocybe'' as then defined was polyphyletic, falling into two distinct clades that are not directly related to each other. The blue-staining hallucinogenic species constituted one clade and the non-bluing species the other. The previous type species of the genus, ''Psilocybe '' (now ''Deconica montana''), was in the non-bluing clade, but in 2010, the type species was changed to '' P. semilanceata'', a member of the bluing clade. A 2006 molecular phylogenetic study of the Agaricales by Matheny and colleagues, further demonstrated the separation of the bluing and non-bluing clades of ''Psilocybe'' in a larger, strongly supported phylogenetic tree of the Agaricales. ''Psilocybe'' had been placed ta ...
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Galerina Marginata
''Galerina marginata'', known colloquially as funeral bell, deadly skullcap, autumn skullcap or deadly galerina, is a species of extremely poisonous mushroom-forming fungus in the family Hymenogastraceae of the order Agaricales. Before 2001, the species ''G. autumnalis'', ''G. oregonensis'', ''G. unicolor'', and ''G. venenata'' were thought to be distinct from ''G. marginata'' due to differences in habitat and the wikt:viscidity, viscidity of their caps, but phylogenetic analysis showed that they are all the same species. The basidiocarp, fruit bodies of the mushroom have brown to yellow-brown pileus (mycology), caps that fade in color when drying. The lamella (mycology), gills are brownish and give a rusty spore print. A well-defined membranous annulus (mycology), ring is typically seen on the stipe (mycology), stems of young specimens but often disappears with age. In older fruit bodies, the caps are flatter and the gills and stems browner. The species ...
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Washington (state)
Washington, officially the State of Washington, is a U.S. state, state in the Pacific Northwest region of the United States. It is often referred to as Washington State to distinguish it from Washington, D.C., the national capital, both named after George Washington (the first President of the United States, U.S. president). Washington borders the Pacific Ocean to the west, Oregon to the south, Idaho to the east, and shares Canada–United States border, an international border with the Provinces and territories of Canada, Canadian province of British Columbia to the north. Olympia, Washington, Olympia is the List of capitals in the United States, state capital, and the most populous city is Seattle. Washington is the List of U.S. states and territories by area, 18th-largest state, with an area of , and the List of U.S. states and territories by population, 13th-most populous state, with a population of just less than 8 million. The majority of Washington's residents live ...
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