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Pruritus
An itch (also known as pruritus) is a sensation that causes a strong desire or reflex to scratch. Itches have resisted many attempts to be classified as any one type of sensory experience. Itches have many similarities to pain, and while both are unpleasant sensory experiences, their behavioral response patterns are different. Pain creates a withdrawal reflex, whereas itches leads to a scratch reflex. Unmyelinated nerve fibers for itches and pain both originate in the skin. Information for them is conveyed centrally in two distinct systems that both use the same nerve bundle and spinothalamic tract. Classification Most commonly, an itch is felt in one place. If it is felt all over the body, then it is called ''generalized itch'' or ''generalized pruritus''. Generalized itch is infrequently a symptom of a serious underlying condition, such as cholestatic liver disease. If the sensation of itching persists for six weeks or longer, then it is called ''chronic itch'' or ''ch ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antipruritic
Antipruritics, abirritants, or anti-itch drugs, are medications that inhibit itching (Latin: ''pruritus''). Itching is often associated with sunburns, allergic reactions, eczema, psoriasis, chickenpox, Fungal infection in animals, fungal infections, insect bites and stings like those from mosquitoes, fleas, mites, and contact dermatitis and urticaria caused by plants such as poison ivy (urushiol-induced contact dermatitis) or stinging nettle. Itching can also be caused by chronic kidney disease and related conditions. Abirritants consist of a large group of drugs belonging to different classes with varying mechanisms to treat itch. They may work either directly or indirectly to relieve itch, and evidence on their effectiveness varies from one class to another. Some alternative medicines are also used to treat itch. Side effects of abirritants also vary depending on the class of the drug. Even before the emergence of modern evidence-based medicine, abirritants had already been used i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Polycythemia Vera
In oncology, polycythemia vera (PV) is an uncommon myeloproliferative neoplasm in which the bone marrow makes too many red blood cells. Approximately 98% of PV patients have a JAK2 gene mutation in their blood-forming cells (compared with 0.1-0.2% of the general population). Most of the health concerns associated with PV, such as thrombosis, are caused by the blood being Hemorheology, thicker as a result of the increased red blood cells. PV may be symptomatic or asymptomatic. Possible symptoms include itching (pruritus), particularly after exposure to warm water, and severe burning pain in the hands or feet that is usually accompanied by a Erythema, reddish or Cyanosis, bluish coloration of the skin. Treatment consists primarily of blood withdrawals (phlebotomy) and oral meds. PV is more common in the elderly. Signs and symptoms Symptoms People with PV can be asymptomatic. Symptoms of PVhttps://www.lls.org/myeloproliferative-neoplasms/polycythemia-vera/signs-and-symptoms t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Atopic Dermatitis
Atopic dermatitis (AD), also known as atopic eczema, is a long-term type of inflammation of the skin. Atopic dermatitis is also often called simply eczema but the same term is also used to refer to dermatitis, the larger group of skin conditions. Atopic dermatitis results in puritis, itchy, red, swollen, and cracked skin. Clear fluid may come from the affected areas, which can thicken over time. Atopic dermatitis affects about 20% of people at some point in their lives. It is more common in younger children. Females are affected slightly more often than males. Many people outgrow the condition. While the condition may occur at any age, it typically starts in childhood, with changing severity over the years. In children under one year of age, the face and limbs and much of the body may be affected. As children get older, the areas on the insides of the knees and folds of the elbows and around the neck are most commonly affected. In adults, the hands and feet are commonly affec ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dermatology
Dermatology is the branch of medicine dealing with the Human skin, skin.''Random House Webster's Unabridged Dictionary.'' Random House, Inc. 2001. Page 537. . It is a speciality with both medical and surgical aspects. A List of dermatologists, dermatologist is a specialist medical doctor who manages diseases related to skin. Etymology Attested in English in 1819, the word "dermatology" derives from the Ancient Greek, Greek δέρματος (''dermatos''), genitive of δέρμα (''derma''), "skin" (itself from δέρω ''dero'', "to flay") and -λογία ''wikt:-logia, -logia''. Neo-Latin ''dermatologia'' was coined in 1630, an anatomical term with various French and German uses attested from the 1730s. History In 1708, the first great school of dermatology became a reality at the famous Hôpital Saint-Louis in Paris, and the first textbooks (Willan's, 1798–1808) and atlases (Jean-Louis-Marc Alibert, Alibert's, 1806–1816) appeared in print around the same time.Freedber ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hedonic
Hedonism is a family of philosophical views that prioritize pleasure. Psychological hedonism is the theory that all human behavior is motivated by the desire to maximize pleasure and minimize pain. As a form of egoism, it suggests that people only help others if they expect a personal benefit. Axiological hedonism is the view that pleasure is the sole source of intrinsic value. It asserts that other things, like knowledge and money, only have value insofar as they produce pleasure and reduce pain. This view divides into quantitative hedonism, which only considers the intensity and duration of pleasures, and qualitative hedonism, which identifies quality as another relevant factor. The closely related position of prudential hedonism states that pleasure and pain are the only factors of well-being. Ethical hedonism applies axiological hedonism to morality, arguing that people have a moral duty to pursue pleasure and avoid pain. Utilitarian versions assert that the goal is to in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Body Louse
The body louse (''Pediculus humanus humanus'', also known as ''Pediculus humanus corporis'') or the cootie is a hematophagic ectoparasite louse that infests humans. It is one of three lice which infest humans, the other two being the head louse, and the crab louse or pubic louse. Body lice may lay eggs on the host's hairs and clothing, but clothing is where the majority of eggs are usually secured. Since body lice cannot jump or fly, they spread by direct contact with another person or more rarely by contact with clothing or bed sheets that are infested. Body lice are disease vectors and can transmit pathogens that cause human diseases such as epidemic typhus, trench fever, and relapsing fever. In developed countries, infestations are only a problem in areas of poverty where there is poor body hygiene, crowded living conditions, and a lack of access to clean clothing. Outbreaks can also occur in situations where large groups of people are forced to live in unsanitary c ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tinea Pedis Interdigitalis
Dermatophytosis, also known as tinea and ringworm, is a fungal infection of the skin (a dermatomycosis), that may affect skin, hair, and nails. Typically it results in a red, itchy, scaly, circular rash. Hair loss may occur in the area affected. Symptoms begin four to fourteen days after exposure. The types of dermatophytosis are typically named for area of the body that they affect. Multiple areas can be affected at a given time. About 40 types of fungus can cause dermatophytosis. They are typically of the '' Trichophyton'', '' Microsporum'', or '' Epidermophyton'' type. Risk factors include using public showers, contact sports such as wrestling, excessive sweating, contact with animals, obesity, and poor immune function. Ringworm can spread from other animals or between people. Diagnosis is often based on the appearance and symptoms. It may be confirmed by either culturing or looking at a skin scraping under a microscope. Prevention is by keeping the skin dry, not wa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Electric Shock
An electrical injury (electric injury) or electrical shock (electric shock) is damage sustained to the skin or internal organs on direct contact with an electric current. The injury depends on the Current density, density of the current, tissue resistance and duration of contact. Very small currents may be imperceptible or only produce a light tingling sensation. However, a shock caused by low and otherwise harmless current could startle an individual and cause injury due to jerking away or falling. A strong electric shock can often cause painful Spasm, muscle spasms severe enough to Joint dislocation, dislocate joints or even to Bone fracture, break bones. The loss of muscle control is the reason that a person may be unable to release themselves from the electrical source; if this happens at a height as on a Overhead power line, power line they can be thrown off. Larger currents can result in tissue damage and may trigger ventricular fibrillation or cardiac arrest. If death res ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Noxious Stimulus
A noxious stimulus is a stimulus strong enough to threaten the body's integrity (i.e. cause damage to tissue). Noxious stimulation induces peripheral afferents responsible for transducing pain (including A-delta and C- nerve fibers, as well as free nerve endings) throughout the nervous system of an organism. The ability to perceive noxious stimuli is a prerequisite for nociception, which itself is a prerequisite for nociceptive pain. A noxious stimulus has been seen to drive nocifensive behavioral responses, which are responses to noxious or painful stimuli. These include reflexive, escape behaviors, to avoid harm to an organism's body. Because of rare genetic conditions that inhibit the ability to perceive physical pain, such acongenital insensitivity to pain and anhydrosis (CIPA) noxious stimulation does not invariably lead to tissue damage. Noxious stimuli can either be mechanical (e.g. pinching or other tissue deformation), chemical (e.g. exposure to acid or i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yawning
A yawn is a reflex in vertebrate animals characterized by a long inspiratory phase with gradual mouth gaping, followed by a brief climax (or acme) with muscle stretching, and a rapid expiratory phase with muscle relaxation, which typically lasts a few seconds. For fish and birds, this is described as gradual mouth gaping, staying open for at least three seconds and subsequently a rapid closure of the mouth. Almost all vertebrate animals, including mammals, birds, reptiles, amphibians, and even fish, experience yawning. The study of yawning is called chasmology. Yawning (oscitation) most often occurs in adults immediately before and after sleep, during tedious activities and as a result of its contagious quality. It is commonly associated with tiredness, stress, sleepiness, boredom, or even hunger. In humans, yawning is often triggered by the perception that others are yawning (for example, seeing a person yawning, or talking to someone on the phone who is yawning). This is a t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
