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Prospect Hill Orthohantavirus
Prospect Hill virus is a single-stranded, negative-sense Hantaan-like zoonotic RNA virus isolated from meadow vole The eastern meadow vole (''Microtus pennsylvanicus''), sometimes called the field mouse or meadow mouse, is a North American vole found in eastern Canada and the United States. Its range extends farther south along the Atlantic coast. The weste ...s and microtine and other cricetid rodents in the United States. It has a widespread distribution in Pennsylvania, Maryland, West Virginia, Minnesota and California. The overall risk of infection in humans is low. It was first isolated from a meadow vole found in Prospect Hill, Maryland for which it is named.Yanagihara R, Daum CA, Lee PW, Baek LJ, Amyx HL, Gajdusek DC, Gibbs CJ Jr.Serological survey of Prospect Hill virus infection in indigenous wild rodents in the USA.Trans R Soc Trop Med Hyg. 1987;81(1):42–5. See also * Isla Vista virus * Hantaan River virus * Bloodland Lake virus References External l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Negative-sense
In molecular biology and genetics, the sense of a nucleic acid molecule, particularly of a strand of DNA or RNA, refers to the nature of the roles of the strand and its complement in specifying a sequence of amino acids. Depending on the context, sense may have slightly different meanings. For example, the negative-sense strand of DNA is equivalent to the template strand, whereas the positive-sense strand is the non-template strand whose nucleotide sequence is equivalent to the sequence of the mRNA transcript. DNA sense Because of the complementary nature of base-pairing between nucleic acid polymers, a double-stranded DNA molecule will be composed of two strands with sequences that are reverse complements of each other. To help molecular biologists specifically identify each strand individually, the two strands are usually differentiated as the "sense" strand and the "antisense" strand. An individual strand of DNA is referred to as positive-sense (also positive (+) or simply sen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Zoonosis
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a virus, bacterium, parasite, fungi, or prion) that can jump from a non-human vertebrate to a human. When humans infect non-humans, it is called reverse zoonosis or anthroponosis. Major modern diseases such as Ebola and salmonellosis are zoonoses. HIV was a zoonotic disease transmitted to humans in the early part of the 20th century, though it has now evolved into a separate human-only disease. Human infection with animal influenza viruses is rare, as they do not transmit easily to or among humans. However, avian and swine influenza viruses in particular possess high zoonotic potential, and these occasionally recombine with human strains of the flu and can cause pandemics such as the 2009 swine flu. Zoonoses can be caused by a range of disease pathogens such as emergent viruses, bacteria, fungi and parasites; of 1,415 pathogens known t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
RNA Virus
An RNA virus is a virus characterized by a ribonucleic acid (RNA) based genome. The genome can be single-stranded RNA (ssRNA) or double-stranded (Double-stranded RNA, dsRNA). Notable human diseases caused by RNA viruses include influenza, SARS, MERS, COVID-19, Dengue virus, hepatitis C, hepatitis E, West Nile fever, Ebola virus disease, rabies, polio, mumps, and measles. All known RNA viruses, that is viruses that use a homologous RNA-dependent polymerase for replication, are categorized by the International Committee on Taxonomy of Viruses (ICTV) into the realm ''Riboviria''. This includes RNA viruses belonging to ''Group III'', ''Group IV'' or ''Group V'' of the Virus classification#Baltimore classification, Baltimore classification system as well as ''Group VI. Group VI'' viruses are retroviruses, viruses with RNA genetic material that use DNA intermediates in their Viral life cycle, life cycle including HIV-1 and HIV-2 which cause AIDS. The majority of such RNA viruses fall ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Meadow Vole
The eastern meadow vole (''Microtus pennsylvanicus''), sometimes called the field mouse or meadow mouse, is a North American vole found in eastern Canada and the United States. Its range extends farther south along the Atlantic coast. The western meadow vole, Florida salt marsh vole, and beach vole were formerly considered regional variants or subspecies of ''M. pennsylvanicus'', but have all since been designated as distinct species. The eastern meadow vole is active year-round, usually at night. It also digs burrows, where it stores food for the winter and females give birth to their young. Although these animals tend to live close together, they are aggressive towards one another. This is particularly evident in males during the breeding season. They can cause damage to fruit trees, garden plants, and commercial grain crops. Taxonomy The species was formerly grouped with the western meadow vole (''M. drummondii'') and the Florida salt marsh vole (''M. dukecampbelli'') ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microtine
The Arvicolinae are a subfamily of rodents that includes the voles, lemmings, and muskrats. They are most closely related to the other subfamilies in the Cricetidae (comprising the hamsters and New World rats and mice). Some authorities place the subfamily Arvicolinae in the family Muridae along with all other members of the superfamily Muroidea. Some refer to the subfamily as the Microtinae (yielding the adjective "microtine") or rank the taxon as a full family, the Arvicolidae. The Arvicolinae are the most populous group of Rodentia in the Northern Hemisphere. They often are found in fossil occlusions of bones cached by past predators such as owls and other birds of prey. Fossils of this group are often used for biostratigraphic dating of paleontological and archeological sites in North America and Europe. Description The most convenient distinguishing feature of the Arvicolinae is the nature of their molar teeth, which have prismatic cusps in the shape of alternating ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cricetid
The Cricetidae are a family of rodents in the large and complex superfamily Muroidea. It includes true hamsters, voles, lemmings, muskrats, and New World rats and mice. At over 870 species, it is either the largest or second-largest family of mammals, and has members throughout the Americas, Europe and Asia. Characteristics The cricetids are small mammals, ranging from just in length and in weight in the New World pygmy mouse up to and in the muskrat. The length of their tails varies greatly in relation to their bodies, and they may be either furred or sparsely haired. The fur of most species is brownish in colour, often with a white underbelly, but many other patterns exist, especially in the cricetine and arvicoline subfamilies. Like the Old World mice, cricetids are adapted to a wide range of habitats, from the high Arctic to tropical rainforests and hot deserts. Some are arboreal, with long balancing tails and other adaptations for climbing, while others are semiaqua ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Frederick County, Maryland
Frederick County is located in Maryland, United States. As of the 2020 United States census, 2020 U.S. census, the population was 271,717. The county seat is Frederick, Maryland, Frederick. The county is part of the Washington metropolitan area, Capital region of the state. Like other outlying sections of the Washington metropolitan area, Frederick County has experienced a rapid population increase since the 1980s. It borders the southern border of Pennsylvania and the northeastern border of Virginia. Catoctin Mountain Park in the county is the location of Camp David, a U.S. presidential retreat, and Fort Detrick, a United States Army, U.S. Army base. Etymology The namesake of Frederick County and its Frederick, Maryland, county seat is unknown, but it was probably either Frederick, Prince of Wales, or Frederick Calvert, 6th Baron Baltimore. History Frederick County was created in 1748 by the Province of Maryland from parts of Prince George's County, Maryland, Prince George's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isla Vista Virus
''Orthohantavirus'' is a genus of viruses that includes all hantaviruses (family ''Hantaviridae'') that cause disease in humans. Orthohantaviruses, hereafter referred to as hantaviruses, are naturally found primarily in rodents. In general, each hantavirus is carried by one rodent species and each rodent that carries a hantavirus carries one hantavirus species. Hantaviruses in their natural reservoirs usually cause an asymptomatic, persistent infection. In humans, however, hantaviruses cause two diseases: hemorrhagic fever with renal syndrome (HFRS) and hantavirus pulmonary syndrome (HPS). HFRS is mainly caused by hantaviruses in Africa, Asia, and Europe, called Old World hantaviruses, and HPS is usually caused by hantaviruses in the Americas, called New World hantaviruses. Hantaviruses are transmitted mainly through aerosols and droplets that contain rodent excretions, as well as through contaminated food, bites, and scratches. Environmental factors such as rainfall, temperature, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hantaan River Virus
Hantaan virus (HTNV) is the main cause of hemorrhagic fever with renal syndrome (HFRS) in East Asia. Hantaan virus is transmitted by the striped field mouse (''Apodemus agrarius'') In its natural reservoir, HTNV causes a persistent, asymptomatic infection and is spread through excretions, fighting, and grooming. Humans can become infected by inhaling aerosols that contain rodent saliva, urine, or feces, as well as through bites and scratches. In humans, infection causes such as fever and headache, as well as the appearance of spots on the skin, hepatitis, and renal symptoms such as kidney swelling, excess protein in urine, blood in urine, decreased urine production, and kidney failure. Rarely, HTNV infection affects the pituitary gland and can cause empty sella syndrome. The case fatality rate from infection is up to 6.3%. The genome of HTNV is about 11.9 kilobases (kb) in length and segmented into three negative-sense, single-stranded RNA (-ssRNA) strands. The small strand en ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bloodland Lake Virus
Bloodland Lake virus (BLLV) is a single-stranded, negative-sense RNA virus of New World ''Orthohantavirus'' first isolated in a Prairie vole (''Microtus ochrogaster'') near Bloodland Lake, Fort Leonard Wood, Pulaski County, Missouri in 1994. BLLV has also been isolated in Prairie voles in St. Louis County, Missouri. Natural reservoir BLLV is unique to the Prairie vole. At the time of its discovery in Pulaski County in 1994, rats and mice trapped along with the Prairie vole tested negative for the virus but did test positive for other hantaviruses. Transmission Transmission is via either direct contact with rodent excreta, or through droplet respiration due to aerosolization of rodent urine, saliva and/or feces. Transmission of hantavirus to humans from arvicoline species in North America has not been documented. To date, the only known transmissions of hantaviruses to humans have come from rats, bats, and mice.Schamljohn, C. S., AND B. Hjelle. 1997. Hantaviruses: a global di ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Viral Diseases
A viral disease (or viral infection) occurs when an organism's body is invaded by pathogenic viruses, and infectious virus particles (virions) attach to and enter susceptible cells. Examples include the common cold, gastroenteritis, COVID-19, the flu, and rabies. Structural characteristics Basic structural characteristics, such as genome type, virion shape and replication site, generally share the same features among virus species within the same family. * Double-stranded DNA families: three are non-enveloped (''Adenoviridae'', '' Papillomaviridae'' and '' Polyomaviridae'') and two are enveloped ('' Herpesviridae'' and ''Poxviridae''). All of the non-enveloped families have icosahedral capsids. * Partly double-stranded DNA viruses: '' Hepadnaviridae''. These viruses are enveloped. * One family of single-stranded DNA viruses infects humans: ''Parvoviridae''. These viruses are non-enveloped. * Positive single-stranded RNA families: three non-enveloped ('' Astroviridae'', '' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hantaviridae
''Hantaviridae'' is a family of viruses in the order ''Bunyavirales''. It is named for the Hantan River area in South Korea South Korea, officially the Republic of Korea (ROK), is a country in East Asia. It constitutes the southern half of the Korea, Korean Peninsula and borders North Korea along the Korean Demilitarized Zone, with the Yellow Sea to the west and t ... where an early outbreak of one of its species was observed. Taxonomy The family contains the following subfamilies and genera (-''virinae'' denotes subfamily and -''virus'' denotes genus): * '' Actantavirinae'' ** '' Actinovirus'' ** '' Percilovirus'' * '' Agantavirinae'' ** '' Agnathovirus'' * '' Mammantavirinae'' ** '' Loanvirus'' ** '' Mobatvirus'' ** '' Orthohantavirus'' ** '' Thottimvirus'' * '' Repantavirinae'' ** '' Reptillovirus'' References {{Taxonbar, from=Q29001075 Virus families Bunyavirales ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
