Price Equation
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Price Equation
In the theory of evolution and natural selection, the Price equation (also known as Price's equation or Price's theorem) describes how a trait or allele changes in frequency over time. The equation uses a covariance between a trait and fitness, to give a mathematical description of evolution and natural selection. It provides a way to understand the effects that gene transmission and natural selection have on the frequency of alleles within each new generation of a population. The Price equation was derived by George R. Price, working in London to re-derive W.D. Hamilton's work on kin selection. Examples of the Price equation have been constructed for various evolutionary cases. The Price equation also has applications in economics. The Price equation is a mathematical relationship between various statistical descriptors of population dynamics, rather than a physical or biological law, and as such is not subject to experimental verification. In simple terms, it is a mathematical s ...
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Evolution
Evolution is the change in the heritable Phenotypic trait, characteristics of biological populations over successive generations. It occurs when evolutionary processes such as natural selection and genetic drift act on genetic variation, resulting in certain characteristics becoming more or less common within a population over successive generations. The process of evolution has given rise to biodiversity at every level of biological organisation. The scientific theory of evolution by natural selection was conceived independently by two British naturalists, Charles Darwin and Alfred Russel Wallace, in the mid-19th century as an explanation for why organisms are adapted to their physical and biological environments. The theory was first set out in detail in Darwin's book ''On the Origin of Species''. Evolution by natural selection is established by observable facts about living organisms: (1) more offspring are often produced than can possibly survive; (2) phenotypic variatio ...
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Chain Rule
In calculus, the chain rule is a formula that expresses the derivative of the Function composition, composition of two differentiable functions and in terms of the derivatives of and . More precisely, if h=f\circ g is the function such that h(x)=f(g(x)) for every , then the chain rule is, in Lagrange's notation, h'(x) = f'(g(x)) g'(x). or, equivalently, h'=(f\circ g)'=(f'\circ g)\cdot g'. The chain rule may also be expressed in Leibniz's notation. If a variable depends on the variable , which itself depends on the variable (that is, and are dependent variables), then depends on as well, via the intermediate variable . In this case, the chain rule is expressed as \frac = \frac \cdot \frac, and \left.\frac\_ = \left.\frac\_ \cdot \left. \frac\_ , for indicating at which points the derivatives have to be evaluated. In integral, integration, the counterpart to the chain rule is the substitution rule. Intuitive explanation Intuitively, the chain rule states that knowing t ...
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Equations
In mathematics, an equation is a mathematical formula that expresses the equality of two expressions, by connecting them with the equals sign . The word ''equation'' and its cognates in other languages may have subtly different meanings; for example, in French an ''équation'' is defined as containing one or more variables, while in English, any well-formed formula consisting of two expressions related with an equals sign is an equation. Solving an equation containing variables consists of determining which values of the variables make the equality true. The variables for which the equation has to be solved are also called unknowns, and the values of the unknowns that satisfy the equality are called solutions of the equation. There are two kinds of equations: identities and conditional equations. An identity is true for all values of the variables. A conditional equation is only true for particular values of the variables. The " =" symbol, which appears in every equation ...
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Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features Peer review, peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2022 ''Journal Citation Reports'' (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in the autumn of 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander MacMillan (publisher), Alexander MacMillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the j ...
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Bodley Head
The Bodley Head is an English book publishing imprint of Penguin Random House. Founded in 1887 by John Lane and Elkin Mathews, The Bodley Head existed as an independent entity or as part of multiple consortia until it was acquired by Random House in 1987 alongside sister companies Jonathan Cape and Chatto & Windus. Random House used The Bodley Head as a children's book imprint until April 2008, when it was repositioned as an adult non-fiction imprint within the Vintage Books division. The Bodley Head launched Penguin Books as an imprint in 1935, which John Lane spun off as an independent company the following year. The Bodley Head acquired several other imprints prior to the Random House acquisition, including Martin Hopkinson and Gerald Howe in 1941, Nonesuch Press in 1953, Werner Laurie in 1957, and Hollis & Carter in 1962. History Originally named Elkin Mathews and John Lane, The Bodley Head was a partnership set up in 1887 by booksellers Elkin Mathews and John Lane, ...
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Proceedings Of The Royal Society B
''Proceedings of the Royal Society'' is the main research journal of the Royal Society. The journal began in 1831 and was split into two series in 1905: * Series A: for papers in physical sciences and mathematics. * Series B: for papers in life sciences. Many landmark scientific discoveries are published in the Proceedings, making it one of the most important science journals in history. The journal contains several articles written by prominent scientists such as Paul Dirac, Werner Heisenberg, Ernest Rutherford, Erwin Schrödinger, William Lawrence Bragg, Lord Kelvin, J.J. Thomson, James Clerk Maxwell, Dorothy Hodgkin and Stephen Hawking. In 2004, the Royal Society began '' The Journal of the Royal Society Interface'' for papers at the interface of physical sciences and life sciences. History The journal began in 1831 as a compilation of abstracts of papers in the ''Philosophical Transactions of the Royal Society'', the older Royal Society publication, that began in 1665. ...
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Heritability
Heritability is a statistic used in the fields of Animal husbandry, breeding and genetics that estimates the degree of ''variation'' in a phenotypic trait in a population that is due to genetic variation between individuals in that population. The concept of heritability can be expressed in the form of the following question: "What is the proportion of the variation in a given trait within a population that is ''not'' explained by the environment or random chance?" Other causes of measured variation in a trait are characterized as environment (biophysical), environmental factors, including observational error. In human studies of heritability these are often apportioned into factors from "shared environment" and "non-shared environment" based on whether they tend to result in persons brought up in the same household being more or less similar to persons who were not. Heritability is estimated by comparing individual phenotypic variation among related individuals in a population, ...
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BioShock 2
''BioShock 2'' is a first-person shooter video game developed by 2K Marin and published by 2K Games. It was released worldwide for PlayStation 3, Microsoft Windows, Windows, and Xbox 360 on February 9, 2010; Feral Interactive released an OS X version on March 30, 2012. The game takes place in the dystopian underwater city of Rapture (BioShock), Rapture, eight years after the events of ''BioShock''. In the single-player campaign, players control the armored protagonist Subject Delta as he fights through Splicers—the psychotic human population of the city—using weapons and an array of genetic modifications. The game includes a story-driven multiplayer mode that takes place before the events of ''BioShock'', during Rapture's civil war. After the success of ''BioShock'', 2K Games formed a new studio, 2K Marin, to create the sequel. 2K Australia, Arkane Studios, and Digital Extremes provided additional support. The developers focused on improving gameplay elements from the first ...
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WΔZ
''WΔZ'' (pronounced ''double-u delta zed)'', is a 2007 British crime horror thriller film directed by Tom Shankland, written by Clive Bradley, and starring Stellan Skarsgård, Melissa George, Selma Blair, and Tom Hardy. The film was released in the United States with the title ''The Killing Gene''. Plot Set against the backdrop of a dark and rain-soaked New York, ''WΔZ'' follows the investigative efforts of Detective Eddie Argo (portrayed by Stellan Skarsgård) and his newly assigned partner Helen Westcott (played by Melissa George). Together, they embark on a journey to solve a series of gruesome murders that have gripped the city. The modus operandi of the perpetrator involves carving the Price equation (wΔz = Cov (w,z) = βwzVz) onto the chests of each victim, presenting a cryptic puzzle for the detectives to unravel. As Eddie Argo and Helen Westcott delve into the intricacies of this enigmatic equation, a chilling revelation emerges – each victim is confronted with ...
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Evolutionary Dynamics
Evolutionary dynamics is the study of the mathematical principles according to which biological organisms as well as cultural ideas evolve and evolved. This is mostly achieved through the mathematical discipline of population genetics, along with evolutionary game theory. Most population genetics considers changes in the frequencies of alleles at a small number of gene loci. When infinitesimal effects at a large number of gene loci are considered, one derives quantitative genetics. Traditional population genetic models deal with alleles and genotypes, and are frequently stochastic. In evolutionary game theory, developed first by John Maynard Smith, evolutionary biology concepts may take a deterministic mathematical form, with selection acting directly on inherited phenotypes. These same models can be applied to studying the evolution of human preferences and ideologies. Many variants on these models have been developed, which incorporate weak selection, mutual population structur ...
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Heterozygote Advantage
A heterozygote advantage describes the case in which the heterozygous genotype has a higher relative fitness (biology), fitness than either the homozygous Dominance (genetics), dominant or homozygous recessive gene, recessive genotype. Loci exhibiting heterozygote advantage are a small minority of loci. The specific case of heterozygote advantage due to a single locus (genetics), locus is known as overdominance. Overdominance is a rare condition in genetics where the phenotype of the heterozygote lies outside of the phenotypical range of both homozygote parents, and heterozygous individuals have a higher fitness (biology), fitness than homozygous individuals. Polymorphism (biology), Polymorphism can be maintained by Natural selection, selection favoring the heterozygote, and this mechanism is used to explain the occurrence of some kinds of genetic variation, genetic variability. A common example is the case where the heterozygote conveys both advantages and disadvantages, while bo ...
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Replicator Equation
In mathematics, the replicator equation is a type of dynamical system used in evolutionary game theory to model how the frequency of strategies in a population changes over time. It is a deterministic, monotone, non-linear, and non-innovative dynamic that captures the principle of natural selection in strategic interactions. The replicator equation describes how strategies with higher-than-average fitness increase in frequency, while less successful strategies decline. Unlike other models of replication—such as the quasispecies model—the replicator equation allows the fitness of each type to depend dynamically on the distribution of population types, making the fitness function an endogenous component of the system. This allows it to model frequency-dependent selection, where the success of a strategy depends on its prevalence relative to others. Another key difference from the quasispecies model is that the replicator equation does not include mechanisms for mutation or th ...
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