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Preventive Mastectomy
A preventive mastectomy or prophylactic mastectomy or risk-reducing mastectomy (RRM) is an elective operation to remove the breasts so that the risk of breast cancer is reduced. Indications The procedure is a surgical option for individuals who are at high risk for the development of breast cancer. High risk women without a prior history of personal breast cancer might consider bilateral risk-reducing mastectomy (BRRM) as an option for minimising the risk of primary breast carcinoma development. The procedure includes the surgical removal of both breasts before any pathologic diagnosis has been made. Women that were previously diagnosed with a breast cancer in one breast (ipsilateral breast cancer) might elect to undergo risk-reducing mastectomy of the other unaffected (contralateral) breast, that is to say contralateral risk-reducing mastectomy (CRRM), to minimize the risk of a second breast cancer development. CRRM has been shown to reduce the incidence of contralateral breast ...
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Elective Surgery
Elective surgery or elective procedure is surgery that is scheduled in advance because it does not involve a medical emergency. Semi-elective surgery is a surgery that must be done to preserve the patient's life, but does not need to be performed immediately. Most surgeries are elective, scheduled at a time to suit the surgeon, hospital, and patient. By contrast, an urgent surgery is one that can wait until the patient is medically stable, but should generally be done within 2 days, and an emergency surgery is one that must be performed without delay; the patient has no choice other than immediate surgery if permanent disability or death is to be avoided. Many surgeries can be performed as either elective or emergency surgeries, depending on the patient's needs. Description An elective surgery or elective procedure (from the , meaning to choose) is a surgery that does not involve a medical emergency and is scheduled in advance. Semi-elective surgery is a surgery that must be ...
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New York Times
''The New York Times'' (''NYT'') is an American daily newspaper based in New York City. ''The New York Times'' covers domestic, national, and international news, and publishes opinion pieces, investigative reports, and reviews. As one of the longest-running newspapers in the United States, the ''Times'' serves as one of the country's Newspaper of record, newspapers of record. , ''The New York Times'' had 9.13 million total and 8.83 million online subscribers, both by significant margins the List of newspapers in the United States, highest numbers for any newspaper in the United States; the total also included 296,330 print subscribers, making the ''Times'' the second-largest newspaper by print circulation in the United States, following ''The Wall Street Journal'', also based in New York City. ''The New York Times'' is published by the New York Times Company; since 1896, the company has been chaired by the Ochs-Sulzberger family, whose current chairman and the paper's publ ...
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Obstetrical And Gynaecological Procedures
Obstetrics is the field of study concentrated on pregnancy, childbirth and the postpartum period. As a medical specialty, obstetrics is combined with gynecology under the discipline known as obstetrics and gynecology (OB/GYN), which is a surgical field. Main areas Prenatal care Prenatal care is important in screening for various complications of pregnancy. This includes routine office visits with physical exams and routine lab tests along with telehealth care for women with low-risk pregnancies: Image:Ultrasound_image_of_a_fetus.jpg, 3D ultrasound of fetus (about 14 weeks gestational age) Image:Sucking his thumb and waving.jpg, Fetus at 17 weeks Image:3dultrasound 20 weeks.jpg, Fetus at 20 weeks First trimester Routine tests in the first trimester of pregnancy generally include: * Complete blood count * Blood type ** Rh-negative antenatal patients should receive RhoGAM at 28 weeks to prevent Rh disease. * Indirect Coombs test (AGT) to assess risk of hemolytic dise ...
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Breast Surgery
Breast surgery is a form of surgery performed on the breast. Types Types include: * Breast augmentation * Breast reduction * Breast-conserving surgery, a less radical cancer surgery than mastectomy * Lumpectomy * Mastectomy * Mastopexy, or breast lift surgery * Microdochectomy (removal of a lactiferous duct) * Surgery for breast abscess, including incision and drainage as well as excision of lactiferous ducts * Surgical breast biopsy Complications After surgical intervention to the breast, complications may arise related to wound healing. As in other types of surgery, hematoma (post-operative bleeding), seroma (fluid accumulation), or incision-site breakdown (wound infection) may occur. Breast hematoma due to an operation will normally resolve with time but should be followed up with more detailed evaluation if it does not. Breast abscess can occur as post-surgical complication, for example after cancer treatment or reduction mammaplasty.Noel Weidner, Chapter ''Infect ...
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Breast Cancer
Breast cancer is a cancer that develops from breast tissue. Signs of breast cancer may include a Breast lump, lump in the breast, a change in breast shape, dimpling of the skin, Milk-rejection sign, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with Metastatic breast cancer, distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a Sedentary lifestyle, lack of physical exercise, alcohol consumption, hormone replacement therapy during menopause, ionizing radiation, an early age at Menarche, first menstruation, having children late in life (or not at all), older age, having a prior history of breast cancer, and a family history of breast cancer. About five to ten percent of cases are the result of an inherited genetic predisposition, including BRCA mutation, ''BRCA'' mutations among others. Breast ...
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Angelina Jolie
Angelina Jolie ( ; born Angelina Jolie Voight, , June 4, 1975) is an American actress, filmmaker, and humanitarian. The recipient of List of awards and nominations received by Angelina Jolie, numerous accolades, including two Academy Awards, a Tony Award and three Golden Globe Awards, she has been named Hollywood's highest-paid actress multiple times. Jolie made her screen debut child actor, as a child alongside her father, Jon Voight, in ''Lookin' to Get Out'' (1982). Her film career began in earnest a decade later with the low-budget production ''Cyborg 2'' (1993), followed by her first leading role in ''Hackers (film), Hackers'' (1995). After starring in the television films ''George Wallace (film), George Wallace'' (1997) and ''Gia'' (1998), Jolie won the Academy Award for Best Supporting Actress for the 1999 drama ''Girl, Interrupted (film), Girl, Interrupted''. Her portrayal of the Lara Croft, titular heroine in ''Lara Croft: Tomb Raider'' (2001) established her as a l ...
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Christina Applegate
Christina Applegate (born November 25, 1971) is an American actress. With a career spanning five decades, her accolades include a Primetime Emmy Award, along with nominations for four Golden Globe Awards and a Tony Award. After appearing in several roles since early childhood, Applegate gained recognition in the late 1980s for playing Kelly Bundy in the Fox Broadcasting Company, Fox sitcom ''Married... with Children'' (1987–1997). For her titular role in the sitcom ''Jesse (TV series), Jesse'' (1998–2000), she earned her first nomination for the Golden Globe Award for Best Actress – Television Series Musical or Comedy, Golden Globe Award for Best Actress. For her guest role in the NBC sitcom ''Friends'' (2002–2003), she won the Primetime Emmy Award for Outstanding Guest Actress in a Comedy Series. She received additional Emmy and Golden Globe nominations for her roles in the television sitcom ''Samantha Who?'' (2007–2009) and the dark tragicomedy series ''Dead to Me (T ...
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Newsweek
''Newsweek'' is an American weekly news magazine based in New York City. Founded as a weekly print magazine in 1933, it was widely distributed during the 20th century and has had many notable editors-in-chief. It is currently co-owned by Dev Pragad, the president and chief executive officer (CEO), and Johnathan Davis, who sits on the board; each owns 50% of the company. In August 2010, revenue decline prompted Graham Holdings, the Washington Post Company to sell ''Newsweek'' to the audio pioneer Sidney Harman for one US dollar and an assumption of the magazine's liabilities. Later that year, ''Newsweek'' merged with the news and opinion website ''The Daily Beast'', forming The Newsweek Daily Beast Company, later called ''NewsBeast''. ''Newsweek'' was jointly owned by the estate of Harman and the company IAC (company), IAC. ''Newsweek'' continued to experience financial difficulties, leading to the suspension of print publication at the end of 2012. In 2013, IBT Media acquired ...
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Lifestyle (sociology)
Lifestyle is the interests, opinions, behaviours, and behavioural orientations of an individual, group, or culture. The term " style of life" () was introduced by Austrian psychologist Alfred Adler in his 1929 book, ''The Case of Miss R.'', with the meaning of "a person's basic character as established early in childhood". The broader sense of lifestyle as a "way or style of living" has been documented since 1961. Lifestyle is a combination of determining intangible or tangible factors. Tangible factors relate specifically to demographic variables, i.e. an individual's demographic profile, whereas intangible factors concern the psychological aspects of an individual such as personal values, preferences, and outlooks. A rural environment has different lifestyles compared to an urban metropolis. Location is important even within an urban scope. The nature of the neighborhood in which a person resides affects the set of lifestyles available to that person due to differences ...
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Oophorectomy
Oophorectomy (; from Greek , , 'egg-bearing' and , , 'a cutting out of'), historically also called ''ovariotomy'', is the surgical removal of an ovary or ovaries. The surgery is also called ovariectomy, but this term is mostly used in reference to non-human animals, e.g. the surgical removal of ovaries from laboratory animals. Removal of the ovaries of females is the biological equivalent of castration of males; the term ''castration'' is only occasionally used in the medical literature to refer to oophorectomy of women. In veterinary medicine, the removal of ovaries and uterus is called ovariohysterectomy ( spaying) and is a form of sterilization. The first reported successful human oophorectomy was carried out by (Sir) Sydney Jones at Sydney Infirmary, Australia, in 1870. Partial oophorectomy or ovariotomy is a term sometimes used to describe a variety of surgeries such as ovarian cyst removal, or resection of parts of the ovaries. This kind of surgery is fertility-preser ...
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Exemestane
Exemestane, sold under the brand name Aromasin among others, is a medication used to treat breast cancer. It is a member of the class of antiestrogens known as aromatase inhibitors. Some breast cancers require estrogen to grow. Those cancers have estrogen receptors (ERs), and are called ER-positive. They may also be called estrogen-responsive, hormonally-responsive, or hormone-receptor-positive. Aromatase is an enzyme that synthesizes estrogen. Aromatase inhibitors block the synthesis of estrogen. This lowers the estrogen level, and slows the growth of cancers. Medical uses Exemestane is indicated for the adjuvant treatment of postmenopausal women with estrogen-receptor positive early breast cancer who have received two to three years of tamoxifen and are switched to it for completion of a total of five consecutive years of adjuvant hormonal therapy. US FDA approval was in October 1999. Exemestane is also indicated for the treatment of advanced breast cancer in postmenopausal w ...
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Raloxifen
Raloxifene, sold under the brand name Evista among others, is a medication used to prevent and treat osteoporosis in postmenopausal women and those on glucocorticoids. For osteoporosis it is less preferred than bisphosphonates. It is also used to reduce the risk of breast cancer in those at high risk. It is taken by mouth. Common side effects include hot flashes, leg cramps, swelling, and joint pain. Severe side effects may include blood clots and stroke. Use during pregnancy may harm the baby. The medication may worsen menstrual symptoms. Raloxifene is a selective estrogen receptor modulator (SERM) and therefore a mixed agonist–antagonist of the estrogen receptor (ER). It has estrogenic effects in bone and antiestrogenic effects in the breasts and uterus. Raloxifene was approved for medical use in the United States in 1997. It is available as a generic medication. In 2020, it was the 292nd most commonly prescribed medication in the United States, with more than 1million ...
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