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Pipotiazine
Pipotiazine (Piportil), also known as pipothiazine, is a typical antipsychotic of the phenothiazine class used in the United Kingdom and other countries for the treatment of schizophrenia. Its properties are similar to those of chlorpromazine. A 2004 systematic review investigated its efficacy for people with schizophrenia: Medical uses Pipotiazine palmitate is used to treat schizophrenia. Contraindications Pipotiazine palmitate is contraindicated in people with circulatory collapse (shock), altered states of consciousness, including drug intoxication, or other serious health conditions (liver disease, kidney disease, pheochromocytoma, severe cardiovascular disease, or blood dyscrasias). It is contraindicated in people with severe depression. Pipotiazine palmitate should not be used in people who have a history of allergic reactions to any component of the medicine or to chemically similar medicines (phenothiazines). Pharmacokinetics Pipotiazine was available as a long-actin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diário Oficial Da União
The ''Diário Oficial da União'' (literally ''Official Diary of the Union''), abbreviated DOU, is the government gazette, official gazette of the Federal Government of Brazil, Federal Government of Brazil. It is published since 1 October 1862 and was created via the Imperial Decree 1,177 of its 9 September as the ''Official Journal of the Empire of Brazil''. Its current name was adopted after Brazil became a federal republic, and the "Union" came into being as the legal personality of the new federal government. The official journal is published by the Imprensa Nacional, Brazilian National Press. Though the journal has been published since 1862, it had many predecessors, as follows: # Gazeta do Rio de Janeiro (10/9/1808 – 29.12.1821) # Gazeta do Rio (1/1/1822 – 31/12/1822) # Diário do Governo (2/1/1823 – 28/6/1833) # Diário Fluminense (21/5/1824 – 24/4/1831) # Correio Oficial (1/7/1833 – 30/6/1836) e (2/1/1830 – 30/12/1840) # Without proper journal (31/12/1840 – ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Circulatory Collapse
Shock is the state of insufficient blood flow to the tissues of the body as a result of problems with the circulatory system. Initial symptoms of shock may include weakness, tachycardia, hyperventilation, sweating, anxiety, and increased thirst. This may be followed by confusion, unconsciousness, or cardiac arrest, as complications worsen. Shock is divided into four main types based on the underlying cause: hypovolemic, cardiogenic, obstructive, and distributive shock. Hypovolemic shock, also known as low volume shock, may be from bleeding, diarrhea, or vomiting. Cardiogenic shock may be due to a heart attack or cardiac contusion. Obstructive shock may be due to cardiac tamponade or a tension pneumothorax. Distributive shock may be due to sepsis, anaphylaxis, injury to the upper spinal cord, or certain overdoses. The diagnosis is generally based on a combination of symptoms, physical examination, and laboratory tests. A decreased pulse pressure (systolic blood pressure minu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
M5 Receptor Antagonists
M5, M-5, M.5, M-V, or M05 may refer to: Transportation Automobiles * AITO M5, a Chinese mid-size crossover SUV * BMW M5, a German mid-size performance car series * Dongfeng Fengxing Lingzhi M5, a Chinese MPV * Haima M5, a Chinese compact sedan * JAC Refine M5, a Chinese MPV * Studebaker M5, an American pickup truck Aviation and aerospace * M-5 rocket, a Japanese rocket * Macchi M.5, an Italian flying boat fighter in service from 1917 until the mid-1920s * Miles M.5 Sparrowhawk, a 1930s British single-seat racing and touring monoplane * Fokker M.5, a 1913 unarmed single-seat monoplane aircraft * Grigorovich M-5, a Russian World War I-era biplane flying boat * Kenmore Air (IATA airline designator: M5), a small airline based in the United States Military * M5 Stuart, a variant of the Stuart tank, a World War II-era American light tank * M5 half-track, a variant of the M3 Half-track military armored personnel carrier * M5 tractor, World War II-era artillery-towing tractor * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
M4 Receptor Antagonists
M4 or M-4 most often refers to: * M4 carbine, an American carbine * M4 Sherman, an American World War II medium tank M4, M04, or M-4 may also refer to: Arts and entertainment * ''M4'' (EP), a 2006 EP by Faunts * ''M4'' (video game), a 1992 computer game developed for the Macintosh * ''M.IV'' ("Matrix IV"), the fictional Warner Brothers videogame project inside the 2021 film '' The Matrix Resurrections'' * Former name of band First to Eleven * M4, the robot assistant to the character Flint in the Star Trek episode Requiem for Methuselah Military Weapons * Benelli M4 Super 90, an Italian semi-automatic,gas-operated shotgun * M4 autocannon, an American 37 mm automatic gun * M4 Selectable Lightweight Attack Munition (SLAM), an American land mine * M4 SLBM, a French submarine-launched ballistic missile from 1985 * M4 Survival Rifle, an American rifle in aircraft survival gear * Spectre M4, an Italian submachine gun * M4 bayonet, an American World War II bayon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
M3 Receptor Antagonists
M3, M-3 or M03 may refer to: Computing and electronics * Apple M3, a central processing unit in the Apple M series * Intel m3, a brand of microprocessors * M.3 (aka NF1/NGSFF), a specification for internally mounted expansion cards * Leica M3, a landmark 35mm rangefinder camera * Modula-3 (M3), a programming language * M3, a British peak programme meter standard used for measuring the volume of audio broadcasts * m3, a macro processor for the AP-3 minicomputer, the predecessor to m4 * M3, a surface-mount version of the 1N4003 general-purpose silicon rectifier diode * M3 (email client), an unreleased email client for the Vivaldi browser Entertainment * M3, a comic book created by Vicente Alcazar * M3 adapter, a Game Boy Advance movie player * M3 (Canadian TV channel), a music and entertainment television channel * M3 (Hungarian TV channel), a Hungarian television channel * '' M3: Malay Mo Ma-develop'', a 2010 Philippine TV series * M3 Music Card, a 2007 flash-based MP ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
M2 Receptor Antagonists
M, or m, is the thirteenth letter of the Latin alphabet, used in the modern English alphabet, the alphabets of several western European languages and others worldwide. Its name in English is ''em'' (pronounced ), plural ''ems''. History The letter M is derived from the Phoenician Mem via the Greek Mu (Μ, μ). Semitic Mem is most likely derived from a " Proto-Sinaitic" (Bronze Age) adoption of the "water" ideogram in Egyptian writing. The Egyptian sign had the acrophonic value , from the Egyptian word for "water", ''nt''; the adoption as the Semitic letter for was presumably also on acrophonic grounds, from the Semitic word for "water", '' *mā(y)-''. Use in writing systems English In English, represents the voiced bilabial nasal . The Oxford English Dictionary (first edition) says that is sometimes a vowel, such as in words like ''spasm'' and in the suffix ''-ism''. In modern terminology, this is described as a syllabic consonant (IPA: ). M is the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
M1 Receptor Antagonists
M1, M01 or M-1 may refer to: Arts, entertainment & media * M-1 (rapper), one half of hip hop duo Dead Prez * Korg M1, a keyboard synthesizer * Leica M1, a 1959 35 mm camera model * Olympus OM-1, a 1972 manually operated 35mm single-lens reflex camera * M1 (TV channel), news channel of the Hungarian MTVA * M-1 (Lithuanian radio station) * M1 (Ukraine), a television channel * M1 (Russian TV channel) Economics and finance * M1 (money supply measure), in economics, a measure of the money supply * M1 Finance, an online financial services company Military equipment Vehicles US Armed Forces * M1 Abrams, a main battle tank * M1 armored car * M1 combat car, an early tank * M1 light tractor * M1 medium tractor * M1 heavy tractor Other * Bristol M.1, a 1916 British fighter aircraft * (M1), a WWI Royal Navy monitor * (1919), an early British submarine * , a Swedish Navy mine sweeper * , a Swedish Royal Navy mine layer Weapons US Armed Forces * 120 mm gun M ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dimethylamino Compounds
Dimethylamine is an organic compound with the formula (CH3)2NH. This secondary amine is a colorless, flammable gas with an ammonia-like odor. Dimethylamine is commonly encountered commercially as a solution in water at concentrations up to around 40%. An estimated 270,000 tons were produced in 2005. Structure and synthesis The molecule consists of a nitrogen atom with two methyl substituents and one hydrogen. Dimethylamine is a base (chemistry), weak base and the pKa of the ammonium CH3--CH3 is 10.73, a value above methylamine (10.64) and trimethylamine (9.79). Dimethylamine reacts with acids to form salts, such as dimethylamine hydrochloride, an odorless white solid with a melting point of 171.5 °C. Dimethylamine is produced by catalytic reaction of methanol and ammonia Ammonia is an inorganic chemical compound of nitrogen and hydrogen with the chemical formula, formula . A Binary compounds of hydrogen, stable binary hydride and the simplest pnictogen hydride, ammoni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pharmacodynamics
Pharmacodynamics (PD) is the study of the biochemistry, biochemical and physiology, physiologic effects of drugs (especially pharmaceutical drugs). The effects can include those manifested within animals (including humans), microorganisms, or combinations of organisms (for example, infection). Pharmacodynamics and pharmacokinetics are the main branches of pharmacology, being itself a topic of biology interested in the study of the interactions of both endogenous and exogenous chemical substances with living organisms. In particular, pharmacodynamics is the study of how a drug affects an organism, whereas pharmacokinetics is the study of how the organism affects the drug. Both together influence dosing, benefit, and adverse effects. Pharmacodynamics is sometimes abbreviated as PD and pharmacokinetics as PK, especially in combined reference (for example, when speaking of PK/PD models). Pharmacodynamics places particular emphasis on dose–response relationships, that is, the relat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1-Bromo-3-chloropropane
1-Bromo-3-chloropropane is an organohalogen compound with the formula Br(CH2)3Cl. It is a colorless liquid, produced by free-radical addition of hydrogen bromide to allyl chloride. It is used as an alkylating agent Alkylation is a chemical reaction that entails transfer of an alkyl group. The alkyl group may be transferred as an alkyl carbocation, a free radical, a carbanion, or a carbene (or their equivalents). Alkylating agents are reagents for effecting ... to install the –(CH2)3Cl and –(CH2)3– groups. For example, it is a precursor to 4-chlorobutyronitrile. References {{DEFAULTSORT:Bromo-3-chloropropane, 1- Bromochloroalkanes ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Half-life
Biological half-life (elimination half-life, pharmacological half-life) is the time taken for concentration of a drug, biological substance (such as a medication) to decrease from its maximum concentration (chemistry), concentration (Cmax (pharmacology), Cmax) to half of Cmax in the blood plasma. It is denoted by the abbreviation t_. This is used to measure the removal of things such as metabolites, drugs, and signalling molecules from the body. Typically, the biological half-life refers to the body's natural detoxification (cleansing) through liver metabolism and through the excretion of the measured substance through the kidneys and intestines. This concept is used when the rate of removal is roughly Exponential function, exponential. In a medical context, half-life explicitly describes the time it takes for the blood plasma concentration of a substance to halve (''plasma half-life'') its steady-state when circulating in the full blood of an organism. This measurement is usefu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
