|
Pimenta Racemosa
''Pimenta racemosa'' is a species of plant in the myrtle family (Myrtaceae) that is native to the Caribbean region. Common names include West Indian bay tree, bay rum tree, and ciliment. Uses It is used in cooking and an essential oil is distilled to produce a fragrant cologne called bay rum; although the name is similar to names of flavored alcoholic beverages, the concentrated essential oil from the fruit is toxic and renders the product undrinkable. The leaves are also used for herbal teas. Anti-inflammatory and antinociceptive properties Extracts from multiple varieties of ''Pimenta racemosa'' display anti-inflammatory properties. These properties are mediated in part by terpenes such as abietic acid and lupeol, which alter neutrophil migration into inflamed regions. ''Pimenta racemosa'' also demonstrates antinociceptive properties and has historically been used as an analgesic in the Caribbean. Description The tree is 4–12 m tall and the white flowers, about ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Philip Miller
Philip Miller Royal Society, FRS (1691 – 18 December 1771) was an English botany, botanist and gardener of Scottish descent. Miller was chief gardener at the Chelsea Physic Garden for nearly 50 years from 1722, and wrote the highly popular ''The Gardeners Dictionary''. Life Born in Deptford or Greenwich, Miller was chief gardener at the Chelsea Physic Garden from 1722 until he was pressured to retire shortly before his death. According to the botanist Peter Collinson (botanist), Peter Collinson, who visited the physic garden in July 1764 and recorded his observation in his commonplace books, Miller "has raised the reputation of the Chelsea Garden so much that it excels all the gardens of Europe for its amazing variety of plants of all orders and classes and from all climates..." He wrote ''The Gardener's and Florists Dictionary or a Complete System of Horticulture'' (1724) and The Gardeners Dictionary, ''The Gardener's Dictionary containing the Methods of Cultivating and Im ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Myrtaceae
Myrtaceae (), the myrtle family, is a family of dicotyledonous plants placed within the order Myrtales. Myrtle, pōhutukawa, bay rum tree, clove, guava, acca (feijoa), allspice, and eucalyptus are some notable members of this group. All species are woody, contain essential oils, and have flower parts in multiples of four or five. The leaves are evergreen, alternate to mostly opposite, simple, and usually entire (i.e., without a toothed margin). The flowers have a base number of five petals, though in several genera, the petals are minute or absent. The stamens are usually very conspicuous, brightly coloured, and numerous. Evolutionary history Scientists hypothesize that the family Myrtaceae arose between 60 and 56 million years ago (Mya) during the Paleocene era. Pollen fossils have been sourced to the ancient supercontinent Gondwana. The breakup of Gondwana during the Cretaceous period (145 to 66 Mya) geographically isolated disjunct taxa and allowed for rapid ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Caribbean
The Caribbean ( , ; ; ; ) is a region in the middle of the Americas centered around the Caribbean Sea in the Atlantic Ocean, North Atlantic Ocean, mostly overlapping with the West Indies. Bordered by North America to the north, Central America to the west, and South America to the south, it comprises numerous List of Caribbean islands, islands, cays, islets, reefs, and banks. It includes the Lucayan Archipelago, Greater Antilles, and Lesser Antilles of the West Indies; the Quintana Roo Municipalities of Quintana Roo#Municipalities, islands and Districts of Belize#List, Belizean List of islands of Belize, islands of the Yucatán Peninsula; and the Bay Islands Department#Islands, Bay Islands, Miskito Cays, Archipelago of San Andrés, Providencia and Santa Catalina, Archipelago of San Andrés, Providencia, and Santa Catalina, Corn Islands, and San Blas Islands of Central America. It also includes the coastal areas on the Mainland, continental mainland of the Americas bordering the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eau De Cologne
Eau de Cologne (; German: ''Kölnisch Wasser'' ; meaning "Water from Cologne") or simply cologne is a perfume originating in Cologne, Germany. Originally mixed by Johann Maria Farina (Giovanni Maria Farina) in 1709, it has since come to be a generic term for scented formulations in typical concentration of 2–5% and also more depending upon its type of essential oils or a blend of extracts, alcohol, and water. In a base of dilute ethanol (70–90%), eau de cologne contains a mixture of citrus oils, including oils of lemon, orange, tangerine, clementine, bergamot, lime, grapefruit, blood orange, bitter orange, and neroli. It can also contain oils of lavender, rosemary, thyme, oregano, petitgrain (orange leaf), jasmine, olive, oleaster, and tobacco. In contemporary American English usage, the term "cologne" has become a generic term for perfumes marketed toward men. It also may signify a less concentrated, more affordable, version of a popular perfume. History ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bay Rum
Bay rum is a type of cologne and aftershave lotion. Other uses include as under-arm deodorant and as a fragrance for shaving soap, as well as a general astringent. Origins It is a distillate that was originally made in Saint Thomas "and probably other West Indian islands" from rum and the leaves and/or berries of the West Indian bay tree, '' Pimenta racemosa''. John Maisch identified the leaf in the herbarium at the Philadelphia Academy of Natural Sciences, collected in Saint Croix, "by the late Dr. Griffith", which was identified as '' Myrcia acris'', now transferred to the genus '' Pimenta''. Maisch added that it was "very probable that various species are made use of for the same purpose." According to an 1889 reference, other ingredients may be citrus and spice oils, the most common being lime oil and oil of cloves. A drop of oil of cloves is added to two parts bay oil and one part pimento oil in one of two recipes for bay rum; the aromatics are steeped in alcohol and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anti-inflammatory
Anti-inflammatory is the property of a substance or treatment that reduces inflammation, fever or swelling. Anti-inflammatory drugs, also called anti-inflammatories, make up about half of analgesics. These drugs reduce pain by inhibiting mechanisms of inflammation, as opposed to opioids, which affect the central nervous system to block pain. Common anti-inflammatory drugs include nonsteroidal anti-inflammatory drugs (NSAIDs), corticosteroids, antileukotrienes, and monoclonal antibodies. Drugs Clinically approved Nonsteroidal anti-inflammatory drugs NSAIDs alleviate pain by counteracting the cyclooxygenase (COX) enzyme involved in pain mechanisms. Some common examples of NSAIDs are aspirin, ibuprofen, and naproxen. Selective COX-2 inhibitors, such as celecoxib, block the enzymatic conversion of arachidonic acid into prostaglandin, inhibiting inflammation and pain. Analgesics commonly associated with anti-inflammatory drugs, such as acetaminophen (paracetamol), hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Terpene
Terpenes () are a class of natural products consisting of compounds with the formula (C5H8)n for n ≥ 2. Terpenes are major biosynthetic building blocks. Comprising more than 30,000 compounds, these unsaturated hydrocarbons are produced predominantly by plants, particularly Pinophyta, conifers. In plants, terpenes and terpenoids are important mediators of ecological biological interaction, interactions, while some insects use some terpenes as a form of defense. Other functions of terpenoids include cell growth modulation and plant elongation, light harvesting and photoprotection, and membrane permeability and fluidity control. Terpenes are classified by the number of carbons: monoterpenes (C10), sesquiterpenes (C15), diterpenes (C20), as examples. The terpene alpha-pinene is a major component of the common solvent, turpentine. The one terpene that has major applications is natural rubber (i.e., polyisoprene). The possibility that other terpenes could be used as precursors to pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Abietic Acid
Abietic acid (also known as ''abietinic acid'' or ''sylvic acid'') is a diterpenoid found in coniferous trees. It is supposed to exist to defend the host plant from insect attack or various wounds. Chemically, it is a complicated molecule featuring two alkene groups and a carboxylic acid within a chiral tricyclic framework. As the major component of rosin, it is commercially important. Historically speaking, it was a major component of naval stores. It is the most common of the resin acids. Another common resin acid is pimaric acid, which converts to abietic acid upon heating. Characteristics and occurrence Abietic acid is found in rosin obtained from pine trees. Pure abietic acid is a colorless solid, but commercial samples are usually a glassy or partly crystalline yellowish solid that melts at temperatures as low as . Abietic acid is soluble in alcohols, acetone, and ethers. Its esters and salts are called an abietates, e.g. ethyl abietate and sodium abietate.Lars-Hugo Norlin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lupeol
Lupeol is a pharmacologically active pentacyclic triterpenoid. It has several potential medicinal properties, like anticancer and anti-inflammatory activity. Natural occurrences Lupeol is found in a variety of plants, including mango, '' Acacia visco'' and '' Abronia villosa''. It is also found in dandelion coffee. Lupeol is present as a major component in ''Camellia japonica'' leaf. Total synthesis The first total synthesis of lupeol was reported by Gilbert Stork ''et al''. In 2009, Surendra and Corey reported a more efficient and enantioselective total synthesis of lupeol, starting from (''1E,5E'')-8- ''2S'')-3,3-dimethyloxiran-2-yl2,6-dimethylocta-1,5-dienyl acetate by use of a polycyclization. Biosynthesis Lupeol is produced by several organisms from squalene epoxide. Dammarane and baccharane skeletons are formed as intermediates. The reactions are catalyzed by the enzyme lupeol synthase. A recent study on the metabolomics of ''Camellia japonica'' leaf revealed ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neutrophil
Neutrophils are a type of phagocytic white blood cell and part of innate immunity. More specifically, they form the most abundant type of granulocytes and make up 40% to 70% of all white blood cells in humans. Their functions vary in different animals. They are also known as neutrocytes, heterophils or polymorphonuclear leukocytes. They are formed from stem cells in the bone marrow and differentiated into subpopulations of neutrophil-killers and neutrophil-cagers. They are short-lived (between 5 and 135 hours, see ) and highly mobile, as they can enter parts of tissue where other cells/molecules cannot. Neutrophils may be subdivided into segmented neutrophils and banded neutrophils (or bands). They form part of the polymorphonuclear cells family (PMNs) together with basophils and eosinophils. The name ''neutrophil'' derives from staining characteristics on hematoxylin and eosin ( H&E) histological or cytological preparations. Whereas basophilic white blood cells ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nociception
In physiology, nociception , also nocioception; ) is the Somatosensory system, sensory nervous system's process of encoding Noxious stimulus, noxious stimuli. It deals with a series of events and processes required for an organism to receive a painful stimulus, convert it to a molecular signal, and recognize and characterize the signal to trigger an appropriate defensive response. In nociception, intense chemical (e.g., capsaicin present in chili pepper or cayenne pepper), mechanical (e.g., cutting, crushing), or thermal (heat and cold) stimulation of sensory neurons called nociceptors produces a signal that travels along a chain of nerve fibers to the brain. Nociception triggers a variety of physiological and behavioral responses to protect the organism against an aggression, and usually results in a subjective experience, or perception, of pain in Sentience, sentient beings. Detection of noxious stimuli Potentially damaging mechanical, thermal, and chemical stimuli are detecte ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Analgesic
An analgesic drug, also called simply an analgesic, antalgic, pain reliever, or painkiller, is any member of the group of drugs used for pain management. Analgesics are conceptually distinct from anesthetics, which temporarily reduce, and in some instances eliminate, sensation, although analgesia and anesthesia are neurophysiologically overlapping and thus various drugs have both analgesic and anesthetic effects. Analgesic choice is also determined by the type of pain: For neuropathic pain, recent research has suggested that classes of drugs that are not normally considered analgesics, such as tricyclic antidepressants and anticonvulsants may be considered as an alternative. Various analgesics, such as many NSAIDs, are available over the counter in most countries, whereas various others are prescription drugs owing to the substantial risks and high chances of overdose, misuse, and addiction in the absence of medical supervision. Etymology The word ''analgesic'' derive ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
