|
Phytantriol
Phytantriol is an aliphatic alcohol used in cosmetic products and as a food additive. At room temperature it is a viscous liquid that is colourless to light yellow and with a sweetish odour. Preparation Phytantriol is prepared by oxidizing isophytol in formic acid, hydrolysis of the product with an inorganic base, and isolation. Uses As a cosmetic ingredient, phytantriol functions to increase moisture retention in skin and hair and helps vitamins and amino acids penetrate. As of 2002 it is found in about 100 cosmetic products, such as hair conditioners, shampoos, and hair tonics, in concentrations from 0.0002% to 1%. Phytantriol is an amphiphile that is the second most used in making cubosomes. Toxicology Oral values were >5000 mg/kg in rats and mice. See also * Phytol Phytol (florasol, phytosol) is an acyclic hydrogenated diterpene alcohol that is used as a precursor for the manufacture of synthetic forms of vitamin E and vitamin K1, as well as in the fragrance ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytol
Phytol (florasol, phytosol) is an acyclic hydrogenated diterpene alcohol that is used as a precursor for the manufacture of synthetic forms of vitamin E and vitamin K1, as well as in the fragrance industry. Its other commercial uses include cosmetics, shampoos, toilet soaps, and detergents, as well as in some cannabis distillates as a diluent or for flavoring. It smells grassy and dominates the aroma of certain green teas. Its worldwide use has been estimated to be approximately 0.1–1.0 metric tons per year. Pharmacology Humans Refsum disease (also known as adult Refsum disease) is an autosomal recessive disorder that results in the accumulation of toxic stores of phytanic acid in tissues and frequently manifests as a variable combination of peripheral polyneuropathy, cerebellar ataxia, retinitis pigmentosa, anosmia, and hearing loss. Although humans cannot derive phytanic acid from chlorophyll, they can convert free phytol into phytanic acid. Thus, patients with Refsum ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Isophytol
Isophytol is a terpenoid alcohol that is used as a fragrance and as an intermediate in the production of vitamin E and K1. Occurrence Isophytol has been in found in two red algae species and more than 15 plant species. Concentrations found have been low. Synthesis It can be synthesized in six steps from pseudoionone and propargyl alcohol. Total synthesis begins with the combination of acetylene and acetone to produce 3-methyl-1-butyn-3-ol. Hydrogenation by palladium catalysis results in 3-methyl-1-buten-3-ol. Reaction with diketene or acetic acid ester creates the acetoacetate; thermal reaction leads to 2-methyl-2-hepten-6-one. The steps of adding acetylene and then isopropenyl methyl ether and hydrogenating the product are done twice (this involves an intermediate of pseudoionone); then acetylene is added to create dehydroisophytol. Hydrogenation results in isophytol. Uses Production industrially was estimated to be 35000 to 40000 tons in 2002, created by total synthesis, wi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Aliphatic
In organic chemistry, hydrocarbons ( compounds composed solely of carbon and hydrogen) are divided into two classes: aromatic compounds and aliphatic compounds (; G. ''aleiphar'', fat, oil). Aliphatic compounds can be saturated (in which all the C-C bonds are single, requiring the structure to be completed, or 'saturated', by hydrogen) like hexane, or unsaturated, like hexene and hexyne. Open-chain compounds, whether straight or branched, and which contain no rings of any type, are always aliphatic. Cyclic compounds can be aliphatic if they are not aromatic. Structure Aliphatics compounds can be saturated, joined by single bonds (alkanes), or unsaturated, with double bonds ( alkenes) or triple bonds ( alkynes). If other elements ( heteroatoms) are bound to the carbon chain, the most common being oxygen, nitrogen, sulfur, and chlorine, it is no longer a hydrocarbon, and therefore no longer an aliphatic compound. However, such compounds may still be referred to as aliph ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
DSM (company)
Koninklijke DSM N.V. (Royal DSM, commonly known as DSM, which is the acronym for ''Dutch State Mines''), was a Dutch multinational corporation active in the fields of health, nutrition and materials. Headquartered in Maastricht, at the end of 2017 DSM employed 21,054 people in approximately 50 countries and posted net Sales (accounting), sales of €8.632 billion in 2018 and €9.204 billion in 2021. In May 2023, it merged with the Swiss company Firmenich to form a new entity named DSM-Firmenich, dsm-firmenich. History DSM was formed by the Dutch state in 1902 to coal mine, mine coal reserves in southern Limburg (Netherlands), Limburg and although the company had diversified into commodity chemicals and petrochemicals by 1973, when the last mine closed, DSM retains a link to its origins by continuing to use the initials, originally an abbreviation for Dutch State Mines, to this day. During World War II researchers worked on penicillin. The code name Bacinol was used ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Formic Acid
Formic acid (), systematically named methanoic acid, is the simplest carboxylic acid. It has the chemical formula HCOOH and structure . This acid is an important intermediate in chemical synthesis and occurs naturally, most notably in some ants. Esters, salts, and the anion derived from formic acid are called formates. Industrially, formic acid is produced from methanol. Natural occurrence Formic acid, which has a pungent, penetrating odor, is found naturally in insects, weeds, fruits and vegetables, and forest emissions. It appears in most ants and in stingless bees of the genus '' Oxytrigona''. Wood ants from the genus ''Formica'' can spray formic acid on their prey or to defend the nest. The puss moth caterpillar (''Cerura vinula'') will spray it as well when threatened by predators. It is also found in the trichomes of stinging nettle (''Urtica dioica''). Apart from that, this acid is incorporated in many fruits such as pineapple (0.21 mg per 100 g), apple (2 mg per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Amphiphile
In chemistry, an amphiphile (), or amphipath, is a chemical compound possessing both hydrophilic (''water-loving'', polar) and lipophilic (''fat-loving'', nonpolar) properties. Such a compound is called amphiphilic or amphipathic. Amphiphilic compounds include surfactants and detergents. The phospholipid amphiphiles are the major structural component of cell membranes. Amphiphiles are the basis for a number of areas of research in chemistry and biochemistry, notably that of lipid polymorphism. Organic compounds containing hydrophilic groups at both ends of the molecule are called bolaamphiphilic. The micelles they form in the aggregate are prolate. Structure The lipophilic group is typically a large hydrocarbon moiety, such as a long chain of the form CH3(CH2)n, with n > 4. The hydrophilic group falls into one of the following categories: # charged groups #* anionic. Examples, with the lipophilic part of the molecule represented by ''R'', are: #** carboxylates: RCO2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cubosomes
Cubosomes are discrete, sub-micron, nanostructured particles of the bicontinuous cubic liquid crystalline phase. The term "bicontinuous" refers to two distinct hydrophilic regions separated by the bilayer. Bicontinuous cubic crystalline materials have been an active research topic because their structure lends itself well to controlled-release applications. Cubosomes are liquid crystalline nano-structures formed from the cubic phase of lipids, such as monooleate, or any other amphiphilic macromolecules with the unique property to be dispersed into particles. Nano-vehicles are generated from a self-assembled lipid mixture and studied by means of high-resolution cryogenic transmission electron microscope (cryo-TEM). These structures have been observed to naturally occur in mitochondrial membranes and in stressed cells. Cubosomes are formed at controlled temperatures into lipid bi-layer twisted into three dimension with minimal surface forming a tightly packed structure with bicon ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Triols
In chemistry, a triol is an organic compound containing three hydroxyl groups ( functional groups), such as . See also * chemical compounds with one hydroxyl group ** ** ** Enols ** Ynols * |
