Phyllobates Samperi
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Phyllobates Samperi
''Phyllobates samperi'', formerly known as sp. aff. ''aurotaenia'' is a new species of hypertoxic poison dart frog, once cited as the "red" form of '' Phyllobates aurotaenia''. It resembles in size and to some extent in colouration to ''P. aurotaenia'', but genetically it is the sister species of the "terrible" frog '' P. terribilis''. It can be distinguished from ''P. aurotaenia'' by the absence of abundant blue or silver specks or marbling in the venter and limbs, its uniform black or bluish-black body, and its orange or red, rather than green or yellow, stripes. The species was named to honour Colombian biologist Cristian Samper, for his lasting impact on the world of conservation, overseeing initiatives that span across 65 countries. He is considered a respected figure in the intersection of science, governance, and activism. Distribution The species is known to occur in the wet forests along the lower San Juan and Dagua river basins in the vicinities of Buenaventura, Vall ...
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Phyllobates Aurotaenia
''Phyllobates aurotaenia'' is a member of the frog family Dendrobatidae, which are found in the tropical environments of Central and South America. First described by zoologist George Albert Boulenger in 1913, ''P. aurotaenia'' is known for being the third most poisonous frog in the world. It is the smallest of the poison dart frogs in the ''Phyllobates'' genus and is endemic to the Pacific coast of Colombia. Wild specimens store batrachotoxin in glands in their skin, which can be fatal to humans in doses as small as 100 μg. The unique lethality of their poison is a trait often exploited by certain Native American peoples of Colombia for hunting. The members of this species are characterized by: black dorsums, sometimes covered by orange suffusions; green, yellow, orange, or brownish gold dorsolateral stripes; and black abdomens with blue or green dots. The name ''Phyllobates aurotaenia'' is currently applied to two forms: a smaller, large-stripe form and a larger, small-st ...
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Golden Poison Frog
The golden poison frog (''Phyllobates terribilis''), also known as the golden dart frog or golden poison arrow frog, is a poison dart frog endemism, endemic from the rainforests of Colombia. The golden poison frog has become endangered due to habitat destruction within its naturally limited range. Despite its small size, this frog is considered to be the most poisonous extant animal species on the planet. Taxonomy and etymology The golden poison frog was described as ''Phyllobates terribilis'' in 1978 by herpetologists Charles W. Myers and Borys Malkin as well as biochemist John W. Daly; the species name ''terribilis'' is a reference to the deadly toxins present in the skin secretions of this species. Myers' research was based on hundreds of specimens collected on an expedition to the Quebrada Guangui and La Brea regions of the Colombian rainforest, and a breeding colony of 18 frogs established at the American Museum of Natural History. Distribution and habitat The golden poi ...
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Phyllobates
''Phyllobates'' is a genus of poison dart frogs native to Central and South America, from Nicaragua to Colombia. There are 3 different Colombian species of ''Phyllobates'', considered highly toxic species due to the poison they contain in the wild. ''Phyllobates'' contains the most poisonous species of frog, the golden poison frog (''P. terribilis''). They are typical of the poison dart frogs, in that all species have bright warning coloration (aposematism), and have varying degrees of toxicity. Only species of ''Phyllobates'' are used by natives of South American tribes as sources of poison for their hunting darts. The most toxic of the many poisonous alkaloids these frogs contain (in glands in their skin) is batrachotoxin, alongside a wide variety of other toxic compounds. Some populations of ''Phyllobates lugubris'' in Central America are not known to be toxic. Taxonomy ''Phyllobates'' (Ancient Greek for "leaf climber") used to contain many of the species which are now withi ...
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Batrachotoxin
Batrachotoxin (BTX) is an extremely potent cardiotoxic and neurotoxic steroidal alkaloid found in certain species of beetles, birds, and frogs. The name is from the Greek word . Structurally-related chemical compounds are often referred to collectively as batrachotoxins. In certain frogs, this alkaloid is present mostly on the skin. Such frogs are among those used for poisoning darts. Batrachotoxin binds to and irreversibly opens the sodium channels of nerve cells and prevents them from closing, resulting in paralysis and death. No antidote is known. History Batrachotoxin was discovered by Fritz Märki and Bernhard Witkop, at the National Institute of Arthritis and Metabolic Diseases, National Institutes of Health, Bethesda, Maryland, U.S.A. Märki and Witkop separated the potent toxic alkaloids fraction from '' Phyllobates bicolor'' and determined its chemical properties in 1963. They isolated four major toxic steroidal alkaloids including batrachotoxin, homobatrachotoxin (is ...
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Neurotoxin
Neurotoxins are toxins that are destructive to nervous tissue, nerve tissue (causing neurotoxicity). Neurotoxins are an extensive class of exogenous chemical neurological insult (medical), insultsSpencer 2000 that can adversely affect function in both developing and mature nervous tissue.Olney 2002 The term can also be used to classify endogenous compounds, which, when abnormally contacted, can prove neurologically toxic. Though neurotoxins are often neurologically destructive, their ability to specifically target neural components is important in the study of nervous systems. Common examples of neurotoxins include lead, ethanol (drinking alcohol), glutamate,Choi 1987 nitric oxide, botulinum toxin (e.g. Botox), tetanus toxin,Simpson 1986 and tetrodotoxin. Some substances such as nitric oxide and glutamate are in fact essential for proper function of the body and only exert neurotoxic effects at excessive concentrations. Neurotoxins inhibit neuron control over ion concentrations ...
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Alkaloid
Alkaloids are a broad class of natural product, naturally occurring organic compounds that contain at least one nitrogen atom. Some synthetic compounds of similar structure may also be termed alkaloids. Alkaloids are produced by a large variety of organisms including bacteria, fungus, fungi, Medicinal plant, plants, and animals. They can be purified from crude extracts of these organisms by acid-base extraction, or solvent extractions followed by silica-gel column chromatography. Alkaloids have a wide range of pharmacology, pharmacological activities including antimalarial medication, antimalarial (e.g. quinine), asthma, antiasthma (e.g. ephedrine), chemotherapy, anticancer (e.g. omacetaxine mepesuccinate, homoharringtonine), cholinomimetic (e.g. galantamine), vasodilation, vasodilatory (e.g. vincamine), Antiarrhythmic agent, antiarrhythmic (e.g. quinidine), analgesic (e.g. morphine), antibacterial (e.g. chelerythrine), and anti-diabetic, antihyperglycemic activities (e.g. berb ...
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Muscle
Muscle is a soft tissue, one of the four basic types of animal tissue. There are three types of muscle tissue in vertebrates: skeletal muscle, cardiac muscle, and smooth muscle. Muscle tissue gives skeletal muscles the ability to muscle contraction, contract. Muscle tissue contains special Muscle contraction, contractile proteins called actin and myosin which interact to cause movement. Among many other muscle proteins, present are two regulatory proteins, troponin and tropomyosin. Muscle is formed during embryonic development, in a process known as myogenesis. Skeletal muscle tissue is striated consisting of elongated, multinucleate muscle cells called muscle fibers, and is responsible for movements of the body. Other tissues in skeletal muscle include tendons and perimysium. Smooth and cardiac muscle contract involuntarily, without conscious intervention. These muscle types may be activated both through the interaction of the central nervous system as well as by innervation ...
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Heart Failure
Heart failure (HF), also known as congestive heart failure (CHF), is a syndrome caused by an impairment in the heart's ability to Cardiac cycle, fill with and pump blood. Although symptoms vary based on which side of the heart is affected, HF typically presents with shortness of breath, Fatigue (medical), excessive fatigue, and bilateral peripheral edema, leg swelling. The severity of the heart failure is mainly decided based on ejection fraction and also measured by the severity of symptoms. Other conditions that have symptoms similar to heart failure include obesity, kidney failure, liver disease, anemia, and thyroid disease. Common causes of heart failure include coronary artery disease, heart attack, hypertension, high blood pressure, atrial fibrillation, valvular heart disease, alcohol use disorder, excessive alcohol consumption, infection, and cardiomyopathy. These cause heart failure by altering the structure or the function of the heart or in some cases both. There are ...
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Fibrillation
Fibrillation is the rapid, irregular, and unsynchronized contraction of muscle fibers. An important occurrence is with regard to the heart. Cardiology There are two major classes of cardiac fibrillation: atrial fibrillation and ventricular fibrillation. * Atrial fibrillation is an irregular and uncoordinated contraction of the cardiac muscle of atria. It can be a chronic condition, usually treated with anticoagulation and sometimes with conversion to normal sinus rhythm. In this condition the normal electrical pulses coming from the sinoatrial node are overwhelmed by disorganized electrical impulses usually originating in the roots of the pulmonary veins, leading to irregular conduction of impulses to the ventricles which generate the heartbeat. * Ventricular fibrillation is an irregular and uncoordinated contraction of the cardiac muscle of ventricles. It is a common cause of cardiac arrest and is usually fatal if not reversed by defibrillation. Fibrillation may sometimes b ...
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Chicken
The chicken (''Gallus gallus domesticus'') is a domesticated subspecies of the red junglefowl (''Gallus gallus''), originally native to Southeast Asia. It was first domesticated around 8,000 years ago and is now one of the most common and widespread domesticated animals in the world. Chickens are primarily kept for chicken as food, their meat and egg as food, eggs, though they are also kept as pets. As of 2023, the global chicken population exceeds 26.5 billion, with more than 50 billion birds produced annually for consumption. Specialized breeds such as broilers and laying hens have been developed for meat and egg production, respectively. A hen bred for laying can produce over 300 eggs per year. Chickens are social animals with complex vocalizations and behaviors, and cultural references to chickens, feature prominently in folklore, religion, and literature across many societies. Their economic importance makes them a central component of global animal husbandry and agricu ...
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Paper Towel
A paper towel is an absorbent, disposable towel made from paper. In Commonwealth English, paper towels for kitchen use are also known as kitchen rolls, kitchen paper, or kitchen towels. For home use, paper towels are usually sold in a roll of perforated sheets, but some are sold in stacks of pre-cut and pre-folded layers for use in paper-towel dispensers. Unlike cloth towels, paper towels are disposable and intended to be used only once. Paper towels absorb water because they are loosely woven, which enables water to travel between the fibers, even against gravity ( capillary effect). They have similar purposes to conventional towels, such as drying hands, wiping windows and other surfaces, dusting, and cleaning up spills. Paper towel dispensers are commonly used in toilet facilities shared by many people (such as at schools or shopping malls), as they are often considered more hygienic than hot-air hand dryers or shared cloth towels. History In 1907, the Philadelphia-based ...
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Endemic Fauna Of Colombia
Endemism is the state of a species being found only in a single defined geographic location, such as an island, state, nation, country or other defined zone; organisms that are indigenous to a place are not endemic to it if they are also found elsewhere. For example, the Cape sugarbird is found exclusively in southwestern South Africa and is therefore said to be ''endemic'' to that particular part of the world. An endemic species can also be referred to as an ''endemism'' or, in scientific literature, as an ''endemite''. Similarly, many species found in the Western ghats of India are examples of endemism. Endemism is an important concept in conservation biology for measuring biodiversity in a particular place and evaluating the risk of extinction for species. Endemism is also of interest in evolutionary biology, because it provides clues about how changes in the environment cause species to undergo range shifts (potentially expanding their range into a larger area or becomin ...
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