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Phototoxic
Phototoxicity, also called photoirritation, is a chemically induced skin irritation, requiring light, that does not involve the immune system. It is a type of photosensitivity. The skin response resembles an exaggerated sunburn. The involved chemical may enter into the skin by topical administration, or it may reach the skin via systemic circulation following ingestion or parenteral administration. The chemical needs to be "photoactive," which means that when it absorbs light, the absorbed energy produces molecular changes that cause toxicity. Many synthetic compounds, including drug substances like tetracyclines or fluoroquinolones, are known to cause these effects. Surface contact with some such chemicals causes photodermatitis, and many plants cause phytophotodermatitis. Light-induced toxicity is a common phenomenon in humans; however, it also occurs in other animals. Scientific background A phototoxic substance is a chemical compound which becomes toxic when exposed to light. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Phytophotodermatitis
Phytophotodermatitis, also known as berloque dermatitis,, margarita photodermatitis,, lime disease or lime phytodermatitis is a cutaneous phototoxic inflammatory reaction resulting from contact with a light-sensitizing botanical agent (such as lime juice) followed by exposure to ultraviolet A (UV-A) light (from the sun, for instance). Symptoms include erythema, edema, blisters (Skin condition#Vesicle, vesicles and/or Skin condition#Bulla, bullae), and delayed hyperpigmentation. Heat and moisture tend to exacerbate the reaction. A reaction may be elicited in any person who has been exposed to adequate amounts of both a photosensitizing, photosensitizer and UV-A light. Phytophotodermatitis is not an Immunology, immunologic response; no prior exposure to the photosensitizing agent is required. The photosensitizing substances found in phototoxic plants belong to a class of chemical compounds called the furanocoumarins, which are activated by long-wavelength ultraviolet (UV-A) ligh ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heracleum Mantegazzianum
''Heracleum mantegazzianum'', commonly known as giant hogweed, is a monocarpic perennial herbaceous plant in the carrot family Apiaceae. ''H. mantegazzianum'' is also known as cartwheel-flower, giant cow parsley, giant cow parsnip, or hogsbane. In New Zealand, it is also sometimes called wild parsnip (not to be confused with ''Pastinaca sativa'') or wild rhubarb. Giant hogweed is native to the western Caucasus region of Eurasia. It was introduced to Britain as an ornamental plant in the 19th century, and has also spread to other areas in Western Europe, the United States, and Canada. Its close relatives, Heracleum sosnowskyi, Sosnowsky's hogweed and Persian hogweed, have similarly spread to other parts of Europe. The sap of giant hogweed is Phototoxicity, phototoxic and causes phytophotodermatitis in humans, resulting in blisters and scars. These serious reactions are due to the furanocoumarin derivatives in the leaves, roots, stems, flowers, and seeds of the plant. Consequ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bergamot Essential Oil
Bergamot essential oil is a cold-pressed essential oil produced by cells inside the rind of a bergamot orange fruit. It is a common flavouring and top note in perfumes. The scent of bergamot essential oil is similar to a sweet light orange peel oil with a floral note. Production The '' sfumatura'' or slow-folding process was the traditional technique for manually extracting the bergamot oil. By more modern methods, the oil is extracted mechanically with machines called peelers, which scrape the outside of the fruit under running water to get an emulsion channeled into centrifuges for separating the essence from the water. The rinds of 100 bergamot oranges yield about of bergamot oil. Uses Bergamot essential oil has been used in cosmetics, aromatherapy, and as a flavoring in food and beverages. Its citrus scent makes it a natural flavoring and deodorizing agent. The volatile oils of the bergamot orange are described as flavoring agents in the USP Food Chemicals ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sunburn
Sunburn is a form of radiation burn that affects living tissue, such as skin, that results from an overexposure to ultraviolet (UV) radiation, usually from the Sun. Common symptoms in humans and other animals include red or reddish skin that is hot to the touch or painful, general fatigue, and mild dizziness. Other symptoms include blistering, peeling skin, swelling, itching, and nausea. Excessive UV radiation is the leading cause of (primarily) non-malignant skin tumors,World Health Organization, International Agency for Research on Cance"Do sunscreens prevent skin cancer" Press release No. 132, 5 June 2000World Health Organization, International Agency for Research on Cance"Solar and ultraviolet radiation" IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Volume 55, November 1997 which in extreme cases can be life-threatening. Sunburn is an inflammatory response in the tissue triggered by direct DNA damage by UV radiation. When the cells' DNA is ov ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lime (fruit)
A lime is a citrus fruit, which is typically round, lime (color), lime green in colour, in diameter, and contains acidic juice vesicles. There are several species of citrus trees whose fruits are called limes, including the Key lime (''Citrus aurantiifolia''), Persian lime, kaffir lime, finger lime, blood lime, and Citrus glauca, desert lime. Limes are a rich source of vitamin C, are sour, and are often used to accent the flavours of foods and beverages. They are grown year-round. Plants with fruit called "limes" have diverse genetic origins; limes do not form a monophyletic group. The term ''lime'' originated in other languages (from French language, French , from Arabic , from Persian language, Persian , ). Plants known as "lime" The difficulty in identifying exactly which species of fruit are called lime in different parts of the English-speaking world (the same problem applies to synonyms in other European languages) is increased by the botanical complexity of the ''Citru ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Common Rue
''Ruta graveolens'', commonly known as rue, common rue or herb-of-grace, is a species of the genus ''Ruta'' grown as an ornamental plant and herb. It is native to the Mediterranean. It is grown throughout the world in gardens, especially for its bluish leaves, and sometimes for its tolerance of hot and dry soil conditions. It is also cultivated as a culinary herb, and to a lesser extent as an insect repellent and incense. Etymology The specific epithet ''graveolens'' refers to the strong-smelling leaves.J. D. Douglas and Merrill C. Tenney Description Rue is a woody, perennial shrub. Its leaves are oblong, blue green and arranged bipinnately with rounded leaflets; they release a strong aroma when they are bruised. The flowers are small with 4 to 5 dull yellow petals in cymes. The first flower in each cyme is pentamerous (five sepals, five petals, five stamens and five carpels. All the others are tetramerous (four of each part). They bear brown seed capsules when pollinate ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heracleum Persicum
''Heracleum persicum'', commonly known as Persian hogweed or by its native name ''golpar'' (), is a species of hogweed, a perennial herbaceous plant in the carrot family Apiaceae. It grows wild in humid mountainous regions in Iran and some adjacent areas. Having been introduced in the 1830s, it has spread across Scandinavia. It is now very common in northern Norway, where one of its names is Tromsø palm (after the city of Tromsø). The plant has also been spotted in Sweden. In Finland, it has been declared an invasive species. Persian hogweed is a polycarpic perennial, that is, a mature plant flowers and bears fruit season after season. Invasiveness status In Europe, Persian hogweed is included since 2016 in the list of Invasive Alien Species of Union concern (the Union list). This implies that this species cannot be imported, cultivated, transported, commercialized, planted, or intentionally released into the environment in the whole of the European Union. Uses Food uses ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Heracleum Sosnowskyi
''Heracleum sosnowskyi'', or Sosnowsky's hogweed, is a monocarpic perennial herbaceous flowering plant in the carrot family Apiaceae. Its native range includes the central and eastern Caucasus regions and Transcaucasia. The native ranges of ''Heracleum sosnowskyi'' and '' H. mantegazzianum'', a close relative, overlap in the Caucasus region. Sosnowsky's hogweed is now a common weed in the Baltic States, Belarus, Poland, Russia, and Ukraine. Description ''Heracleum sosnowskyi'' is in height, with a straight, firm stem that can reach a diameter of . The leaves are long. The root is very firm, up to diameter. The inflorescence is a big umbel found at the end of every stem. It blooms from July to September and produces thousands of seeds, which are easily distributed by wind, but especially by water. As Sosnowsky's hogweed is a monocarpic perennial species, the entire plant (including the root) dies after flowering and producing seed. Similar species Similarly tall invasi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Essential Oils
An essential oil is a concentrated hydrophobic liquid containing volatile (easily evaporated at normal temperatures) chemical compounds from plants. Essential oils are also known as volatile oils, ethereal oils, aetheroleum, or simply as the oil of the plant from which they were extracted, such as oil of clove. An essential oil is essential in the sense that it contains the essence of the plant's fragrance—the characteristic fragrance of the plant from which it is derived. The term "essential" used here does ''not'' mean required or usable by the human body, as with the terms essential amino acid or essential fatty acid, which are so called because they are nutritionally required by a living organism. Essential oils are generally extracted by distillation, often by using steam. Other processes include expression, solvent extraction, '' sfumatura'', absolute oil extraction, resin tapping, wax embedding, and cold pressing. They are used in perfumes, cosmetics, soaps, a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psoralen
Psoralen (also called psoralene) is the parent compound in a family of naturally occurring organic compounds known as the linear furanocoumarins. It is structurally related to coumarin by the addition of a fused furan ring, and may be considered as a derivative of umbelliferone. Psoralen occurs naturally in the seeds of ''Psoralea corylifolia'', as well as in the common fig, celery, parsley, Zanthoxylum, West Indian satinwood, and in all citrus fruits. It is widely used in PUVA (psoralen + Ultraviolet#Subtypes, UVA) treatment for psoriasis, eczema, vitiligo, and cutaneous T-cell lymphoma; these applications are typically through the use of medications such as Methoxsalen. Many furanocoumarins are extremely toxic to fish, and some are deposited in streams in Indonesia to catch fish. Uses Psoralen is a mutagen, and is used for this purpose in molecular biology research. Psoralen Intercalation (biochemistry), intercalates into DNA and on exposure to ultraviolet (UVA) radiation can f ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tetracycline Antibiotics
Tetracyclines are a group of broad-spectrum antibiotic compounds that have a common basic structure and are either isolated directly from several species of ''Streptomyces'' bacteria or produced semi-synthetically from those isolated compounds. Tetracycline molecules comprise a linear fused tetracyclic nucleus (rings designated A, B, C and D) to which a variety of functional groups are attached. Tetracyclines are named after their four ("tetra-") hydrocarbon rings ("-cycl-") derivation ("-ine"). They are defined as a subclass of polyketides, having an octahydrotetracene-2-carboxamide skeleton and are known as derivative (chemistry), derivatives of polycyclic naphthacene carboxamide. While all tetracyclines have a common structure, they differ from each other by the presence of chloro, methyl, and hydroxyl groups. These chemical modification, modifications do not change their broad antibacterial activity, but do affect pharmacological properties such as half-life and binding to pr ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Porphyria
Porphyria ( or ) is a group of disorders in which substances called porphyrins build up in the body, adversely affecting the skin or nervous system. The types that affect the nervous system are also known as Porphyria#Acute porphyrias, acute porphyria, as symptoms are rapid in onset and short in duration. Symptoms of an attack include abdominal pain, chest pain, vomiting, confusion, constipation, fever, hypertension, high blood pressure, and tachycardia, high heart rate. The attacks usually last for days to weeks. Complications may include paralysis, hyponatraemia, low blood sodium levels, and seizures. Attacks may be triggered by Alcohol (drug), alcohol, smoking, hormonal changes, fasting, stress, or certain medications. If the skin is affected, blisters or itching may occur with sunlight exposure. Most types of porphyria are inherited from one or both of a person's parents and are due to a mutation in one of the genes that make heme. They may be inherited in an autosomal dom ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
