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Photorhabdus
''Photorhabdus'' is a genus of bioluminescent, gram-negative bacilli which lives symbiotically within entomopathogenic nematodes, hence the name ''photo'' (which means light producing) and ''rhabdus'' (rod shape). ''Photorhabdus'' is known to be pathogenic to a wide range of insects and has been used as biopesticide in agriculture. Life cycle ''Photorhabdus'' species facilitate the reproduction of entomopathogenic nematodes by infecting and killing susceptible insect larvae. Entomopathogenic nematodes are normally found in soil. Nematodes infect larval hosts by piercing the larval cuticle. When the nematode enters an insect larvae, ''Photorhabdus'' species are released by the nematodes and will produce a range of toxins, killing the host within 48 hours. ''Photorhabdus'' species feed on the cadaver of the insect and the process converts the cadaver into a nutrient source for the nematode. Mature nematodes leave the depleted body of the insect and search for new hosts to infect. ...
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Photorhabdus Luminescens
''Photorhabdus luminescens'' (previously called ''Xenorhabdus luminescens'') is a Gammaproteobacterium of the family Morganellaceae, and is a lethal pathogen of insects. It lives in the gut of an entomopathogenic nematode of the family Heterorhabditidae. When the nematode infects an insect, ''P. luminescens'' is released into the blood stream and rapidly kills the insect host (within 48 hours) by producing toxins, such as the high molecular weight insecticidal protein complex Tca. ''P. luminescens'' also produces a proteic toxin through the expression of a single gene called ''makes caterpillars floppy'' (mcf). It also secretes enzymes which break down the body of the infected insect and bioconvert it into nutrients which can be used by both nematode and bacteria. In this way, both organisms gain enough nutrients to replicate (or reproduce in the case of the nematode) several times. The bacteria enter the nematode progeny as they develop. 3,5-Dihydroxy-4-isopropyl-trans-sti ...
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Photorhabdus Temperata
''Photorhabdus temperata'' is a species of bacteria. It has been divided into 6 subspecies. It is pathogenic to certain insects. References Further reading * * * * External linksLPSNType strain of ''Photorhabdus temperata'' at Bac''Dive'' - the Bacterial Diversity Metadatabase
Enterobacterales Bacteria described in 1999 {{Enterobacterales-stub ...
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Morganellaceae
The Morganellaceae are a family of Gram-negative bacteria that include some important human pathogens formerly classified as Enterobacteriaceae. This family is a member of the order Enterobacterales in the class Gammaproteobacteria of the phylum Pseudomonadota. Genera in this family include the type genus '' Morganella'', along with '' Arsenophonus, Cosenzaea, Moellerella, Photorhabdus, Proteus, Providencia'' and '' Xenorhabdus''. The name ''Morganellaceae'' is derived from the Latin term ''Morganella'', referring the type genus of the family and the suffix "-aceae", an ending used to denote a family. Together, ''Morganellaceae'' refers to a family whose nomenclatural type is the genus ''Morganella''. Human pathogens A number of Morganellaceae bacterial species are opportunistic human pathogens, including ''Proteus'', '' Providencia'', and occasionally '' Morganella'' in nosocomial settings. ''Proteus'' Three ''Proteus'' species '' P. vulgaris'', '' P. mirabilis'', and ...
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Benvitimod
Tapinarof, also known as benvitimod and sold under the brand name Vtama among others, is a medication used for the treatment of plaque psoriasis. The medication is applied to the skin. Besides its use in medicine, tapinarof is a naturally occurring compound found in bacterial symbionts of nematodes which has antibiotic properties. The medication acts as an aryl hydrocarbon receptor agonist. Tapinarof was approved for medical use in the United States in May 2022. The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. Medical uses Tapinarof is indicated for the treatment of plaque psoriasis in adults. Side effects In case of short term use the most common adverse effects are folliculitis, contact dermatitis, headache, pruritus (itching), and upper respiratory tract infection. Pharmacology Mechanism of action Tapinarof binds directly to topical aryl hydrocarbon receptor (AhR), suppressing inflammatory cytokines, modulating skin bar ...
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Heterorhabditis
''Heterorhabditis'' is a genus of nematodes belonging to the order Rhabditida. All species of this genus are obligate parasites of insects, and some are used as biological control agents for the control of pest insects. ''Heterorhabditis'' nematodes are hosts for the '' Photorhabdus'' bacterial symbiont Symbiosis (Ancient Greek : living with, companionship < : together; and ''bíōsis'': living) is any type of a close and long-term biological interaction, between two organisms of different species. The two organisms, termed symbionts, can fo ...
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Species

The recognized species in this genus are: * '' Heterorhabditis amazonensis'' Andaló, Nguyen & Moino, 2007 * '' Heterorhabditis bacteri ...
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Ostrinia Furnacalis
''Ostrinia furnacalis'' is a species of moth in the family Crambidae, the grass moths. It was described by Achille Guenée in 1854 and is known by the common name Asian corn borer since this species is found in Asia and feeds mainly on corn crop. The moth is found from China to Australia, including in Java, Sulawesi, the Philippines, Borneo, New Guinea, the Solomon Islands, and Micronesia. The Asian corn borer is part of the species complex, ''Ostrinia'', in which members are difficult to distinguish based on appearance. Other ''Ostrinia'' such as '' O. orientalis'', '' O. scapulalis'', '' O. zealis'', and '' O. zaguliaevi'' can occur with ''O. furnacalis'', and the taxa can be hard to tell apart. This moth exhibits unique acoustic mimicry of a predator by mirroring the echolocation calls of bats in order to temporarily paralyze female moths and make it easier to mate. It is also well known as being an agricultural pest on several crops in the western Pacific region of Asia, es ...
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Enterobacterales
Enterobacterales is an order of Gram-negative bacteria, Gram-negative, non-spore forming, Facultative anaerobic organism, facultatively anaerobic, rod-shaped bacteria with the class Gammaproteobacteria. The type genus of this order is ''Enterobacter.'' The name Enterobacterales is derived from the Latin term ''Enterobacter'', referring the type genus of the order and the suffix "-ales", an ending used to denote an order. Together, Enterobacterales refers to an order whose nomenclatural type is the genus ''Enterobacter''. Historical Identification and Systematics Enterobacterales was proposed in 2005 under the name "Enterobacteriales". However, the name "Enterobacteriales" was not validated according to the rules of the ''International Code of Nomenclature of Prokaryotes,'' thus it lacked standing in nomenclature, so the name was written in parentheses. "Enterobacteriales" was a monotypic order, containing only the family ''Enterobacteriaceae'', and shared its type genus ''Esch ...
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Entomopathogenic Nematode
Entomopathogenic nematodes (EPN) are a group of nematodes (thread worms), that cause death to insects. The term ''entomopathogenic'' has a Greek origin, with ''entomon'', meaning ''insect'', and ''pathogenic'', which means ''causing disease''. They are animals that occupy a bio control middle ground between microbial pathogens and predator/ parasitoids. Although many other parasitic thread worms cause diseases in living organisms (sterilizing or otherwise debilitating their host), entomopathogenic nematodes are specific in only infecting insects. Entomopathogenic nematodes (EPNs) live parasitically inside the infected insect host, and so they are termed as ''endoparasitic''. They infect many different types of insects living in the soil like the larval forms of moths, butterflies, flies and beetles as well as adult forms of beetles, grasshoppers and crickets. EPNs have been found all over the world in a range of ecologically diverse habitats. They are highly diverse, complex and s ...
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Polyketide
In organic chemistry, polyketides are a class of natural products derived from a Precursor (chemistry), precursor molecule consisting of a Polymer backbone, chain of alternating ketone (, or Carbonyl reduction, its reduced forms) and Methylene group, methylene () groups: . First studied in the early 20th century, discovery, biosynthesis, and application of polyketides has evolved. It is a large and diverse group of secondary metabolites caused by its complex biosynthesis which resembles that of fatty acid synthesis. Because of this diversity, polyketides can have various medicinal, agricultural, and industrial applications. Many polyketides are medicinal or exhibit acute toxicity. Biotechnology has enabled discovery of more naturally-occurring polyketides and evolution of new polyketides with novel or improved bioactivity. History Naturally produced polyketides by various plants and organisms have been used by humans since before studies on them began in the 19th and 20th century ...
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Hemocytes
A blood cell (also called a hematopoietic cell, hemocyte, or hematocyte) is a cell produced through hematopoiesis and found mainly in the blood. Major types of blood cells include red blood cells (erythrocytes), white blood cells (leukocytes), and platelets (thrombocytes). Together, these three kinds of blood cells add up to a total 45% of the blood tissue by volume, with the remaining 55% of the volume composed of plasma, the liquid component of blood. Red blood cells Red blood cells or ''erythrocytes'' primarily carry oxygen and collect carbon dioxide through the use of hemoglobin. Hemoglobin is an iron-containing protein that gives red blood cells their color and facilitates transportation of oxygen from the lungs to tissues and carbon dioxide from tissues to the lungs to be exhaled. Red blood cells are the most abundant cell in the blood, accounting for about 40–45% of its volume. Red blood cells are circular, biconcave, disk-shaped and deformable to allow them to sque ...
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