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Peyton Jacob III
Peyton Jacob III is an American chemist and pharmacologist who has studied nicotine, methamphetamine, hallucinogens, entactogens, and other psychoactive drugs. He is a researcher at the University of California, San Francisco (UCSF). Jacob extensively collaborated with and was close friends with Alexander Shulgin. Among many other contributions, they developed the Shulgin Rating Scale together and methylone Methylone, also known as 3,4-methylenedioxy-''N''-methylcathinone (MDMC), is an entactogen and stimulant drug of the amphetamine, cathinone, and benzodioxole families related to 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"). It is th ... was first synthesized and described by the pair in the mid-1990s. Selected publications * * * * * * * * * * * References {{DEFAULTSORT:Jacob, Peyton III Alexander Shulgin American chemists American pharmacologists Living people Purdue University alumni Psychedelic drug researchers University of California ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Davis
The University of California, Davis (UC Davis, UCD, or Davis) is a Public university, public Land-grant university, land-grant research university in Davis, California, United States. It is the northernmost of the ten campuses of the University of California system. The institution was first founded as an Agriculture, agricultural branch of the system in 1905 and became the sixth campus of the University of California in 1959. Founded as a primarily agricultural campus, the university has expanded over the past century to include graduate and professional programs in UC Davis School of Medicine, medicine (which includes the UC Davis Medical Center), UC Davis College of Engineering, engineering, UC Davis College of Letters and Science, science, UC Davis School of Law, law, UC Davis School of Veterinary Medicine, veterinary medicine, UC Davis School of Education, education, Betty Irene Moore School of Nursing, nursing, and UC Davis Graduate School of Management, business managemen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hamilton Morris
Hamilton Morris (born April 14, 1987) is an American journalist, documentarian, and scientific researcher. He is the creator and director of the television series ''Hamilton's Pharmacopeia'', in which he investigated the chemistry, history, and cultural impact of various psychoactive drugs. Morris is considered to be one of the world's leading drug journalists. Biography Hamilton Morris was born in New York City, the son of Julia Sheehan, an art historian, and documentary filmmaker Errol Morris. He was raised in Cambridge, Massachusetts. As a teenager, Morris appeared in television commercials, notably a 2002 advertisement for the first-generation iPod. He attended the University of Chicago and The New School, where he studied anthropology and chemistry. He earned a bachelor of science (BSc) degree in liberal arts from The New School. Morris's interest in psychoactive substances blossomed in his late teens when he began reading pharmacology information hosted on websites su ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Purdue University Alumni
Purdue University is a public land-grant research university in West Lafayette, Indiana, United States, and the flagship campus of the Purdue University system. The university was founded in 1869 after Lafayette businessman John Purdue donated land and money to establish a college of science, technology, and agriculture; the first classes were held on September 16, 1874. Purdue University is a member of the Association of American Universities and is classified among "R1: Doctoral Universities – Very high research activity". Purdue enrolls the largest student body of any individual university campus in Indiana, as well as the ninth-largest foreign student population of any university in the United States. The university is home to the oldest computer science program in the United States. Purdue is the founding member of the Big Ten Conference and sponsors 18 intercollegiate sports teams. It has been affiliated with 13 Nobel laureates, 1 Turing Award laureate, 1 Bharat ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Purpose: Because living persons may suffer personal harm from inappropriate information, we should watch their articles carefully. By adding an article to this category, it marks them with a notice about sources whenever someone tries to edit them, to remind them of WP:BLP (biographies of living persons) policy that these articles must maintain a neutral point of view, maintain factual accuracy, and be properly sourced. Recent changes to these articles are listed on Special:RecentChangesLinked/Living people. Organization: This category should not be sub-categorized. Entries are generally sorted by family name In many societies, a surname, family name, or last name is the mostly hereditary portion of one's personal name that indicates one's family. It is typically combined with a given name to form the full name of a person, although several give .... Maintenance: Individuals of advanced age (over 90), for whom there has been no new documentation in the last ten ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Pharmacologists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label that was previously known as Def American * American University, in Washington, D.C. Sports teams S ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Neurobiological Technologies
Neurobiological Technologies, Inc. ("NTI") was a biotechnology company that was founded in 1987 by Enoch Callaway and John B. Stuppin to in-license and develop drugs primarily to treat neurological conditions; the company was dissolved in 2009 after the failure of its drug candidate ancrod in a Phase III trial for ischemic stroke. NTI-Children's license is included in the filing. The company pursued a virtual company model from the beginning, keeping staff as small as possible and outsourcing tasks to contract research organizations and contract manufacturing organizations. At the time the company made its first public offering in 1996, it had three products in development: memantine, a small molecule for neuropathic pain and AIDS-related dementia, corticotropin-releasing factor, a biopharmaceutical to treat edema caused by brain tumors and inflammation caused by rheumatoid arthritis, and dynorphin A, a biopharmaceutical to treat pain. It licensed patents covering methods to us ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Synthesis
Chemical synthesis (chemical combination) is the artificial execution of chemical reactions to obtain one or several products. This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable. A chemical synthesis involves one or more compounds (known as '' reagents'' or ''reactants'') that will experience a transformation under certain conditions. Various reaction types can be applied to formulate a desired product. This requires mixing the compounds in a reaction vessel, such as a chemical reactor or a simple round-bottom flask. Many reactions require some form of processing (" work-up") or purification procedure to isolate the final product. The amount produced by chemical synthesis is known as the '' reaction yield''. Typically, yields are expressed as a mass in grams (in a laboratory setting) or as a percentage of the total theoretical quantity that could be produced based ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Methylone
Methylone, also known as 3,4-methylenedioxy-''N''-methylcathinone (MDMC), is an entactogen and stimulant drug of the amphetamine, cathinone, and benzodioxole families related to 3,4-methylenedioxymethamphetamine (MDMA; "ecstasy"). It is the β- keto or cathinone analogue of MDMA. Methylone is usually taken orally, but is also used by other routes. The drug acts as a serotonin–norepinephrine–dopamine releasing agent (SNDRA). It has much less activity at the vesicular monoamine transporter 2 (VMAT2) than MDMA and may have less serotonergic neurotoxicity. In contrast to certain other entactogens like MDMA, methylone does not appear to be a significant agonist of the serotonin 5-HT2 receptors. Methylone is similar in its effects to MDMA, producing entactogenic effects and euphoria, but has a reputation of being gentler than MDMA and only lasts about half as long. Side effects of methylone include tachycardia, hangover, and insomnia. It may have reduced negative ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Shulgin Rating Scale
The Shulgin Rating Scale (or "quantitative potency scale") is a simple scale for reporting the subjective effect of psychoactive substances at a given dosage, and at a given time. The system was developed for research purposes by the American biochemist Alexander Shulgin, and published with co-authors Ann Shulgin and Peyton Jacob, III, in a 1986 issue of the journal ''Methods and Findings in Experimental and Clinical Pharmacology''. It was later described in the Shulgins' popular 1991 book ''PIHKAL: A Chemical Love Story''. ''PIHKAL'' Glossary excerpts Usage ''Shulgin Ratings'' typically include three components. An identification of the chemical being ingested, a dosage, and a descriptive narrative including the ratings themselves used to describe various moments in time. The chemical itself must be clearly identified, preferably using chemical nomenclature, as opposed to popular or "street" names. The dosage must be known and communicated, as substances may result in wildly d ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alexander Shulgin
Alexander Theodore "Sasha" Shulgin (June 17, 1925 – June 2, 2014) was an American biochemist, broad researcher of synthetic psychoactive compounds, and author of works regarding these, who independently explored the organic chemistry and pharmacology of such agents—in his mid-life and later, many through preparation in his home laboratory, and testing on himself. He is acknowledged to have introduced to broader use, in the late 1970s, the previously-synthesized compound MDMA ("ecstasy"), in research psychopharmacology and in combination with conventional therapy, the latter through presentations and academic publications, including to psychologists; and for the rediscovery, occasional discovery, and regular synthesis and personal use and distribution, of possibly hundreds of Psychoactive drug, psychoactive compounds (for their Psychedelic drug, psychedelic and MDMA-like empathogenic bioactivity, bioactivities). As such, Shulgin is seen both as a pioneering and a controversi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Psychoactive Drug
A psychoactive drug, psychopharmaceutical, mind-altering drug, consciousness-altering drug, psychoactive substance, or psychotropic substance is a chemical substance that alters psychological functioning by modulating central nervous system activity. Psychoactive and psychotropic drugs both affect the brain, with psychotropics sometimes referring to psychiatric drugs or high-abuse substances, while “drug” can have negative connotations. Designer drug, Novel psychoactive substances are designer drugs made to mimic illegal ones and bypass laws. Psychoactive drug use dates back to prehistory for medicinal and consciousness-altering purposes, with evidence of widespread cultural use. Many animals intentionally consume psychoactive substances, and some traditional legends suggest animals first introduced humans to their use. Psychoactive substances are used across cultures for purposes ranging from medicinal and therapeutic treatment of Mental disorder, mental disorders and pain, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
