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Peter Lawrence (biologist)
Peter Anthony Lawrence (born 23 June 1941) is a British developmental biologist and geneticist . He was a staff scientist of the MRC Laboratory of Molecular Biology from 1969 to 2006 and has worked in thZoology Departmentof the University of Cambridge from 2006 to present. Education Lawrence was educated at Wennington School in Wetherby, and then at St Catharine's College, Cambridge; he gained his doctorate as a student of Vincent Wigglesworth for work on ''Oncopeltus fasciatus'' (milkweed bug). His postdoc in the USA was funded by a Harkness Fellowship. Career and research Lawrence's main discoveries lie in trying to understand the information that shapes an animal or generates a pattern (such as on a butterfly wing or a fingerprint). He is a principal advocate of the theory that cells in a gradient of a morphogen each develop according to the local concentration of that morphogen and that this mechanism thereby patterns fields of cells. Together with Ginés Morata, he has ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Oxford University Press
Oxford University Press (OUP) is the publishing house of the University of Oxford. It is the largest university press in the world. Its first book was printed in Oxford in 1478, with the Press officially granted the legal right to print books by decree in 1586. It is the second-oldest university press after Cambridge University Press, which was founded in 1534. It is a department of the University of Oxford. It is governed by a group of 15 academics, the Delegates of the Press, appointed by the Vice Chancellor, vice-chancellor of the University of Oxford. The Delegates of the Press are led by the Secretary to the Delegates, who serves as OUP's chief executive and as its major representative on other university bodies. Oxford University Press has had a similar governance structure since the 17th century. The press is located on Walton Street, Oxford, Walton Street, Oxford, opposite Somerville College, Oxford, Somerville College, in the inner suburb of Jericho, Oxford, Jericho. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Homeotic Selector Gene
Homeotic selector genes confer segment identity in ''Drosophila''. They encode homeodomain proteins which interact with Hox and other homeotic genes to initiate segment-specific gene regulation. Homeodomain proteins are transcription factors that share a DNA-binding domain called the homeodomain. Changes in the expression and function of homeotic genes are responsible for the changes in the morphology of the limbs of arthropods as well as in the axial skeletons of vertebrates. Mutations in homeotic selector genes do not lead to elimination of a segment or pattern, but instead cause the segment to develop incorrectly. History The homeotic selector genes were discovered through the genetic analysis of Drosophila over 80 years ago . Unusual disturbances were found in the organization of the adult fly, resulting in misplaced limbs, such as legs developing where antennae usually develop or an extra pair of wings developing where halteres should be. This discovery provided a glimpse to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leverhulme Trust
The Leverhulme Trust () is a large national grant-making organisation in the United Kingdom. It was established in 1925 under the will of the 1st Viscount Leverhulme (1851–1925), with the instruction that its resources should be used to cover certain trade charities and support "scholarships for the purposes of research and education." Over time, it has come to focus on the latter aim. The Trust is based in London and is a registered charity under English law. The current Chair of the Trust is Alan Jope CBE. Activities Since its foundation in 1925, the Trust has provided funding for research projects, fellowships, studentships, bursaries and prizes. It operates across all academic disciplines with the intention of supporting individuals in research and professional training. Dispensing over £100 million a year, the Trust is one of the largest providers of research funding in the UK. The Trust places special weight on: * the originality of the projects put to them; * th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wellcome Trust
The Wellcome Trust is a charitable foundation focused on health research based in London, United Kingdom. It was established in 1936 with legacies from the pharmaceutical magnate Henry Wellcome (founder of Burroughs Wellcome, one of the predecessors of GSK plc) to fund research to improve human and animal health. The aim of the Trust is to "support science to solve the urgent health challenges facing everyone." It had a financial endowment of £29.1 billion in 2020, making it the fourth wealthiest charitable foundation in the world. In 2012, the Wellcome Trust was described by the ''Financial Times'' as the United Kingdom's largest provider of non-governmental funding for scientific research, and one of the largest providers in the world. According to their annual report, the Wellcome Trust spent GBP £1.1 billion on charitable activities across their 2019/2020 financial year. According to the OECD, the Wellcome Trust's financing for 2019 development increased by 2 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Medical Research Council (United Kingdom)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a conseq ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Open Biology
''Open Biology'' is a peer-reviewed open access scientific journal published by the Royal Society covering biology at the molecular and cellular levels. The first issue was published in September 2011 with an editorial about the launch of the journal. The editor-in-chief is Jonathon Pines ( The Institute of Cancer Research) who was appointed in 2020. Contents and themes The journal publishes research articles, reviews, invited perspectives, commentaries, comments, and invited replies. Abstracting and indexing The journal is abstracted and indexed in the Science Citation Index Expanded, BIOSIS Previews, Scopus, and Index Medicus/MEDLINE/PubMed. According to the ''Journal Citation Reports ''Journal Citation Reports'' (''JCR'') is an annual publication by Clarivate. It has been integrated with the Web of Science and is accessed from the Web of Science Core Collection. It provides information about academic journals in the natur ...'', the journal has a 2023 impact factor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Development (journal)
''Development'' is a bi-weekly peer-reviewed scientific journal in the field of developmental biology that covers cellular and molecular mechanisms of animal and plant development. It is published by The Company of Biologists. ''Development'' is partnered with Publons, is part of the Review Commons initiative and has two-way integration with bioRxiv. In 2009, the BioMedical & Life Sciences Division of the Special Libraries Association included ''Development'' in their list of top 100 journals in Biology and Medicine over the last 100 years. Brief history Originally called ''Journal of Embryology and Experimental Morphology'' () and established in 1953, the journal provided a periodical that would be primarily devoted to morphogenesis. In 1987, the journal was renamed ''Development''. The journal's full archive from 1953 is available online. ''Development'' is now a hybrid journal and publishes 24 issues a year. Content over 6 months old is free to read. Scope and content ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature Reviews Genetics
''Nature Reviews Genetics'' is a monthly review journal published by Nature Portfolio. It was established in 2000 and covers the full breadth of modern genetics. The editor-in-chief is Linda Koch. The journal publishes review and perspective articles written by experts in the field subject to peer review and copy editing to provide authoritative coverage of topics. Each issue also contains Research Highlight articles – short summaries written by the editors that describe recent research papers. According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a type of journal ranking. Journals with higher impact factor values are considered more prestigious or important within their field. The Impact Factor of a journa ... of 59.943, ranking it 1st out of 175 journals in the category "Genetics & Heredity". References External links * Genetics journals Nature Research ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Planar Cell Polarity
Planar cell polarity (PCP) is the protein-mediated Cell signaling, signaling that coordinates the orientation of Cell (biology), cells in a layer of Epithelium, epithelial tissue. In vertebrates, examples of mature PCP oriented tissue are the stereo-cilia bundles in the inner ear, motile cilia of the epithelium, and cell motility in epidermal wound healing. Additionally, PCP is known to be crucial to major developmental time points including coordinating convergent extension during gastrulation and coordinating cell behavior for neural tube closure. Cells orient themselves and their neighbors by establishing asymmetric expression of PCP components on opposing cell members within cells to establish and maintain the directionality of the cells. Some of these PCP components are transmembrane proteins which can proliferate the orientation signal to the surrounding cells. Research history Planar cell polarity was first described in insects and then further defined in fruit flies (''Dro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gary Struhl
Gary Struhl is an American research scientist whose primary areas of research are developmental biology and genetics and genomics. He works as a professor at Columbia University Medical Center, teaching neuroscience within the Department of Genetics and Development. Personal life and education Gary Struhl has a brother, Kevin Struhl, who was also recognized as a member of the National Academy of Sciences. Both Gary and Kevin studied at MIT for their undergraduate degrees, but Gary attended Cambridge for his doctorate degree while Kevin completed his studies at Stanford University. Both did postdoctoral research at Cambridge, but their research differs, as Kevin works on eukaryotic gene regulation. Struhl obtained his undergraduate degree from the Massachusetts Institute of Technology. He received his doctorate from the University of Cambridge in the United Kingdom, and then he completed his postdoctoral fellowships both at the University of Cambridge and at Harvard University. H ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature New Biology
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2022 ''Journal Citation Reports'' (with an ascribed impact factor of 50.5), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in the autumn of 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander MacMillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in e ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Embryology And Experimental Morphology
''Development'' is a bi-weekly peer-reviewed scientific journal in the field of developmental biology that covers cellular and molecular mechanisms of animal and plant development. It is published by The Company of Biologists. ''Development'' is partnered with Publons, is part of the Review Commons initiative and has two-way integration with bioRxiv. In 2009, the BioMedical & Life Sciences Division of the Special Libraries Association included ''Development'' in their list of top 100 journals in Biology and Medicine over the last 100 years. Brief history Originally called ''Journal of Embryology and Experimental Morphology'' () and established in 1953, the journal provided a periodical that would be primarily devoted to morphogenesis. In 1987, the journal was renamed ''Development''. The journal's full archive from 1953 is available online. ''Development'' is now a hybrid journal and publishes 24 issues a year. Content over 6 months old is free to read. Scope and content ''De ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
