Permissive Hypotension
Permissive hypotension or hypotensive resuscitation is the use of restrictive fluid therapy, specifically in the trauma patient, that increases systemic blood pressure without reaching normotension (normal blood pressures). The goal blood pressure for these patients is a mean arterial pressure of 40-50 mmHg or systolic blood pressure of less than or equal to 80. This goes along with certain clinical criteria. Following traumatic injury, some patients experience hypotension (low blood pressure) that is usually due to blood loss (hemorrhage) but can be due to other causes as well (for example, blood leaking around an abdominal aortic aneurysm). In the past, physicians were very aggressive with fluid resuscitation (giving fluids such as normal saline or lactated Ringer's through the vein) to try to bring the blood pressure to normal values. Recent studies have found that there is some benefit to allowing specific patients to experience some degree of hypotension in certain settings. T ...
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Crystalloid Fluid
Crystalloid may refer to: *A substance that, when dissolved, forms a true solution and is able to pass through a semipermeable membrane. They get separated from colloids during dialysis. *Crystalloid solution, a type of volume expander A volume expander is a type of intravenous therapy that has the function of providing volume for the circulatory system. It may be used for fluid replacement or during surgery to prevent nausea and vomiting after surgery. Physiology When blood is ...

Hemorrhagic Shock
Hypovolemic shock is a form of shock caused by severe hypovolemia (insufficient blood volume or extracellular fluid in the body). It can be caused by severe dehydration or blood loss. Hypovolemic shock is a medical emergency; if left untreated, the insufficient blood flow can cause damage to organs, leading to multiple organ failure. In treating hypovolemic shock, it is important to determine the cause of the underlying hypovolemia, which may be the result of bleeding or other fluid losses. To minimize ischemic damage to tissues, treatment involves quickly replacing lost blood or fluids, with consideration of both rate and the type of fluids used. Tachycardia, a fast heart rate, is typically the first abnormal vital sign. When resulting from blood loss, trauma is the most common root cause, but severe blood loss can also happen in various body systems without clear traumatic injury. The body in hypovolemic shock prioritizes getting oxygen to the brain and heart, which reduces ...
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Crystalloid Fluid
Crystalloid may refer to: *A substance that, when dissolved, forms a true solution and is able to pass through a semipermeable membrane. They get separated from colloids during dialysis. *Crystalloid solution, a type of volume expander A volume expander is a type of intravenous therapy that has the function of providing volume for the circulatory system. It may be used for fluid replacement or during surgery to prevent nausea and vomiting after surgery. Physiology When blood is ...

Triad Of Death
Triad or triade may refer to: * a group of three Humanities * Trichotomy (philosophy), often called triads * Triad (sociology), a group of three people as a unit of study * Triad (relationship), or ''ménage à trois'' Music * Triad (music), chord consisting of root, third and fifth Science and technology * Triad (anatomy), structure in skeletal muscles, formed by a T tubule surrounded by sarcoplasmic reticulum * Triad (computing), 3 bits of information storage * Triad (environmental science), management system for environmental cleanup * Triad (monitors), group of three phosphor dots used in some computer monitors * List of medical triads, tetrads, and pentads * A nuclear triad * Triad, a brand name of the combination medication butalbital/acetaminophen * The TRIAD Method for determining spacecraft attitude Religion * Triad (religion), a grouping of three gods As a proper name Businesses and organisations * Triad (American fraternities), certain historic gr ...
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Hypothermia
Hypothermia is defined as a body core temperature below in humans. Symptoms depend on the temperature. In mild hypothermia, there is shivering and mental confusion. In moderate hypothermia, shivering stops and confusion increases. In severe hypothermia, there may be hallucinations and paradoxical undressing, in which a person removes their clothing, as well as an increased risk of the heart stopping. Hypothermia has two main types of causes. It classically occurs from exposure to cold weather and cold water immersion. It may also occur from any condition that decreases heat production or increases heat loss. Commonly, this includes alcohol intoxication but may also include low blood sugar, anorexia and advanced age. Body temperature is usually maintained near a constant level of through thermoregulation. Efforts to increase body temperature involve shivering, increased voluntary activity, and putting on warmer clothing. Hypothermia may be diagnosed based on either a ...
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Core Body Temperature
Normal human body temperature (normothermia, euthermia) is the typical temperature range found in humans. The normal human body temperature range is typically stated as . Human body temperature varies. It depends on sex, age, time of day, exertion level, health status (such as illness and menstruation), what part of the body the measurement is taken at, state of consciousness (waking, sleeping, sedated), and emotions. Body temperature is kept in the normal range by a homeostatic function known as thermoregulation, in which adjustment of temperature is triggered by the central nervous system. Methods of measurement Taking a human's temperature is an initial part of a full clinical examination. There are various types of medical thermometers, as well as sites used for measurement, including: * In the rectum (rectal temperature) * In the mouth (oral temperature) * Under the arm (axillary temperature) * In the ear (tympanic temperature) * On the skin of the forehead over the ...
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Room Temperature
Room temperature, colloquially, denotes the range of air temperatures most people find comfortable indoors while dressed in typical clothing. Comfortable temperatures can be extended beyond this range depending on humidity, air circulation, and other factors. In certain fields, like science and engineering, and within a particular context, room temperature can mean different agreed-upon ranges. In contrast, ambient temperature is the actual temperature, as measured by a thermometer, of the air (or other medium and surroundings) in any particular place. The ambient temperature (e.g. an unheated room in winter) may be very different from an ideal ''room temperature''. Food and beverages may be served at "room temperature", meaning neither heated nor cooled. Comfort temperatures Comfort temperature is interchangeable with neutral temperature in the scientific literature, which can be calculated through regression analysis between thermal sensation votes and indoor temperature. ...
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In Vivo
Studies that are ''in vivo'' (Latin for "within the living"; often not italicized in English) are those in which the effects of various biological entities are tested on whole, living organisms or cells, usually animals, including humans, and plants, as opposed to a tissue extract or dead organism. Examples of investigations ''in vivo'' include: the pathogenesis of disease by comparing the effects of bacterial infection with the effects of purified bacterial toxins; the development of non-antibiotics, antiviral drugs, and new drugs generally; and new surgical procedures. Consequently, animal testing and clinical trials are major elements of ''in vivo'' research. ''In vivo'' testing is often employed over ''in vitro'' because it is better suited for observing the overall effects of an experiment on a living subject. In drug discovery, for example, verification of efficacy ''in vivo'' is crucial, because ''in vitro'' assays can sometimes yield misleading results with drug c ...
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Coagulation
Coagulation, also known as clotting, is the process by which blood changes from a liquid to a gel, forming a thrombus, blood clot. It results in hemostasis, the cessation of blood loss from a damaged vessel, followed by repair. The process of coagulation involves Platelet-activating factor, activation, Cell adhesion, adhesion and aggregation of platelets, as well as deposition and maturation of fibrin. Coagulation begins almost instantly after an injury to the endothelium that lines a blood vessel. Exposure of blood to the subendothelial space initiates two processes: changes in platelets, and the exposure of subendothelial Tissue factor, platelet tissue factor to coagulation factor VII, which ultimately leads to cross-linked fibrin formation. Platelets immediately form a plug at the site of injury; this is called ''primary hemostasis. Secondary hemostasis'' occurs simultaneously: additional coagulation factors beyond factor VII (#Coagulation factors, listed below) respond in a c ...
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National Trauma Data Bank
The National Trauma Data Bank (NTDB), also called the American College of Surgeons National Trauma Data Bank, is a compilation of information about traumatic injuries and outcomes in the United States. Hospital emergency rooms and other institutions such as trauma centers which are participants submit data and receive in return access to reports analyzing data about both their own operations and trauma medicine in the United States as a whole.Homepage National Trauma Data Bank
accessed October 8, 2010 Annual reports, an annual report and a pediatric report, which include

Trauma Center
A trauma center, or trauma centre, is a hospital equipped and staffed to provide care for patients suffering from major traumatic injuries such as falls, motor vehicle collisions, or gunshot wounds. The term "trauma center" may be used incorrectly to refer to an emergency department (also known as a "casualty department" or "accident and emergency") that lacks the presence of specialized services or certification to care for victims of major trauma. In the United States, a hospital can receive trauma center status by meeting specific criteria established by the American College of Surgeons (ACS) and passing a site review by the Verification Review Committee. Official designation as a trauma center is determined by individual state law provisions. Trauma centers vary in their specific capabilities and are identified by "Level" designation, Level I (Level-1) being the highest and Level III (Level-3) being the lowest (some states have four or five designated levels). The highe ...
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Prehospital
Emergency medical services (EMS), also known as ambulance services, pre-hospital care or paramedic services, are emergency services that provide urgent pre-hospital treatment and stabilisation for serious illness and injuries and transport to definitive care. They may also be known as a first aid squad, FAST squad, emergency squad, ambulance squad, ambulance corps, life squad or by other acronym, initialisms such as EMAS or EMARS. In most places, EMS can be summoned by members of the public (as well as medical facilities, other emergency services, businesses and authorities) via an emergency telephone number (such as 911 in the United States) which puts them in contact with a dispatching centre, which will then dispatch suitable resources for the call. Ambulances are the primary vehicles for delivering EMS, though Nontransporting EMS vehicle, squad cars, Motorcycle ambulance, motorcycles, Air medical services, aircraft, Water ambulance, boats, Firefighting apparatus, fire appara ...
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