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Pericardial Heart Valves
The pericardial heart valve was invented by Marian Ionescu, a British surgeon working at the General Infirmary in Leeds, England. He created this artificial bioprosthetic heart valve as a three-cusp structure made of chemically treated bovine pericardium attached to a Dacron cloth-covered titanium frame.Ionescu M I, Tandon A P, Silverton N P, et al. "Long-term durability of the pericardial valve". In: Bodnar E, Yacoub M (Eds) ''Biologic and Bioprosthetic Valves. Proceedings of the Third International Symposium''Yorke Medical Books (1986) New York, pages 165–176 The Realisation of a concept The experimental and in vitro testing of this novel device took place in 1970, and in March 1971, Ionescu began, for the first time, the implantation of the pericardial valve in all three cardiac positions in humans. Between 1971 and 1976 the valves had been made in Ionescu's own hospital laboratory. Throughout these five years of usage in 212 patients the performance of the pericardial valve w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Marian Ionescu
Marian Ion Ionescu (21 August 1929 – 12 October 2023) was a Romanian-born British cardiac surgeon. His interest in heart surgery covered several aspects of this specialty. He was an inventor of surgical devices, mostly artificial heart valves, a scientist in the broad term and a medical educator. Ionescu died on 12 October 2023, at the age of 94. Medicine Marian Ionescu's entire medical career was dominated by scientific curiosity and a persistent desire and ability to make progress by creating change, by discovering the unknown, by improving the known and by inventing what he thought would be useful. In 1959 in Cleveland, at Dr Kolff's impulse, he created the first 'single leaflet aortic valve' out of polyurethane. This device never went beyond the experimental stage due to clot formation. During 1961 and 1962 in Romania, he conducted, with his team, extensive experimental and clinical work on the physiology of organisms under deep hypothermia, with the aid of extracorporeal ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |