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Patrick D. Wall (scientist)
Patrick David Wall (25 April 1925 – 8 August 2001) was a British neuroscientist described as 'the world's leading expert on pain' and best known for the gate control theory of pain. Early life and education Wall was born in Nottingham on 25 April 1925 to Thomas Wall, the director of education for Middlesex, and his wife Ruth Cresswell. He was educated at St Paul's School, London and the University of Oxford, studying medicine at Christ Church, Oxford, where he became interested in pain. He published his first two papers, in the prominent science journals ''Brain'' and ''Nature'', at the age of 21. While at Oxford he had also helped found the British Medical Students' Journal, partially to help campaign for the introduction of the National Health Service (NHS). He graduated in 1948, by which time he had published three papers in prominent science journals. Career and research After graduating, he spent a short time treating holocaust survivors and refugees in mainland Europ ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nottingham
Nottingham ( , locally ) is a city and unitary authority area in Nottinghamshire, East Midlands, England. It is located north-west of London, south-east of Sheffield and north-east of Birmingham. Nottingham has links to the legend of Robin Hood and to the lace-making, bicycle and tobacco industries. The city is also the county town of Nottinghamshire and the settlement was granted its city charter in 1897, as part of Queen Victoria's Diamond Jubilee celebrations. Nottingham is a tourist destination; in 2018, the city received the second-highest number of overnight visitors in the Midlands and the highest number in the East Midlands. In 2020, Nottingham had an estimated population of 330,000. The wider conurbation, which includes many of the city's suburbs, has a population of 768,638. It is the largest urban area in the East Midlands and the second-largest in the Midlands. Its Functional Urban Area, the largest in the East Midlands, has a population of 919,484. The popu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gate Control Theory
The gate control theory of pain asserts that non-painful input closes the nerve "gates" to painful input, which prevents pain sensation from traveling to the central nervous system. The gate control theory of pain describes how non-painful sensations can override and reduce painful sensations. A painful, nociceptive stimulus stimulates primary afferent fibers and travels to the brain via transmission cells. Increasing activity of the transmission cells results in increased perceived pain. Conversely, decreasing activity of transmission cells reduces perceived pain. In the gate control theory, a closed "gate" describes when input to transmission cells is blocked, therefore reducing the sensation of pain. An open “gate” describes when input to transmission cells is permitted, therefore allowing the sensation of pain. First proposed in 1965 by Ronald Melzack and Patrick Wall, the theory offers a physiological explanation for the previously observed effect of psychology on pain perc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Jerusalem
Jerusalem (; he, יְרוּשָׁלַיִם ; ar, القُدس ) (combining the Biblical and common usage Arabic names); grc, Ἱερουσαλήμ/Ἰεροσόλυμα, Hierousalḗm/Hierosóluma; hy, Երուսաղեմ, Erusałēm. is a city in Western Asia. Situated on a plateau in the Judaean Mountains between the Mediterranean Sea, Mediterranean and the Dead Sea, it is one of the List of oldest continuously inhabited cities, oldest cities in the world and is considered to be a holy city for the three major Abrahamic religions: Judaism, Christianity, and Islam. Both Israelis and Palestinians claim Jerusalem as their Capital city, capital, as Israel maintains its primary governmental institutions there and the State of Palestine ultimately foresees it as its seat of power. Because of this dispute, Status of Jerusalem, neither claim is widely recognized internationally. Throughout History of Jerusalem, its long history, Jerusalem has been destroyed at least twice, Sie ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
John Zachary Young
John Zachary Young FRS (18 March 1907 – 4 July 1997), generally known as "JZ" or "JZY", was an English zoologist and neurophysiologist, described as "one of the most influential biologists of the 20th century". Biography Young went to school at Marlborough College. In 1928, he received a first class honours degree in zoology from Magdalen College, Oxford. On Oct. 12, 1942, Young spoke at the Socratic Club in Oxford on the topic "Purpose and Design in Nature" as part of the series of talks and debates led by C. S. Lewis. He was elected a Fellow of the Royal Society in 1945 and served as Professor of Anatomy at University College London from then until 1974. The following year, he became a Professor Emeritus and proposed a degree programme in the Human Sciences. Young was elected to the American Academy of Arts and Sciences in 1957. Among his other honors are a Linnean Medal for zoology from the Linnean Society of London, awarded in 1973. He was elected to the American Philos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Pain (journal)
''Pain'' is a monthly peer-reviewed medical journal published by Lippincott Williams & Wilkins on behalf of the International Association for the Study of Pain. The journal was established in 1975 and covers research and reviews in the fields of anesthesiology and clinical neurology. The editor-in-chief is Francis J. Keefe (Duke University). Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', the journal has a 2018 impact factor of 6.029. References External links * {{Authority control Anesthesiology and palliative medicine journals Monthly journals English-language journals Publications established in 1975 Lippincott Williams & Wilkins academic journals Academic journals associated with learned and professional societies ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Association For The Study Of Pain
The International Association for the Study of Pain (IASP) is an international learned society promoting research, education, and policies for the understanding, prevention, and treatment of pain. IASP was founded in 1973 under the leadership of John J. Bonica. Its secretariat, formerly based in Seattle, Washington, is now located in Washington, D.C. It publishes the scientific journal ''PAIN, PAIN Reports'' and ''PAIN: Clinical Updates.'' IASP currently has more than 7,200 members from 133 countries and in 94 chapters worldwide. IASP supports 20 Special Interest Groups (SIGs) which members may join to network and collaborate with others in their specific field of research or practice. Global Year Against Pain In 2004, supported by various IASP chapters and federations holding their own local events and activities worldwide, IASP initiated its first "Global Year Against Pain" with the motto "The Relief of Pain Should be a Human Right". Every year, the focus is on another aspect ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcutaneous Electrical Nerve Stimulator
wikt:transcutaneous, Transcutaneous electrical nerve stimulation (TENS or TNS) is the use of electric current produced by a device to stimulate the nerves for therapeutic purposes. TENS, by definition, covers the complete range of transcutaneously applied currents used for nerve excitation although the term is often used with a more restrictive intent, namely to describe the kind of pulses produced by portable stimulators used to reduce pain. The unit is usually connected to the skin using two or more electrodes which are typically conductive gel pads. A typical battery-operated TENS unit is able to modulate pulse width, frequency, and intensity. Generally, TENS is applied at high frequency (>50 Hz) with an intensity below motor contraction (sensory intensity) or low frequency ( * Over a tumor/malignancy (based on in vitro experiments where electricity promotes cell growth) * Directly over the spinal column TENS used across an artificial Artificial pacemaker, cardiac pacem ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ronald Melzack
Ronald Melzack (July 19, 1929 – December 22, 2019) was a Canadian psychologist and professor of psychology at McGill University. In 1965, he and Patrick David Wall revolutionized pain research by introducing the gate control theory of pain. In 1968, Melzack published an extension of the gate control theory, in which he asserted that pain is subjective and multidimensional because several parts of the brain contribute to it at the same time. During the mid-1970s, he developed the McGill Pain Questionnaire and became a founding member of the International Association for the Study of Pain. He also became the founding editor of '' Wall & Melzack's Textbook of Pain'' Melzack has received numerous honors including Prix du Québec (1994), the Order of Canada (1995), and the National Order of Quebec (2000). In 2010, he won the Grawemeyer Award for his research on the science of pain. Early life Melzack was born in Montreal, the son of Joseph Melzack, who worked in a clothing fa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lobotomies
A lobotomy, or leucotomy, is a form of Neurosurgery, neurosurgical treatment for mental disorder, psychiatric disorder or neurological disorder (e.g. epilepsy) that involves severing connections in the brain's prefrontal cortex. The surgery causes most of the connections to and from the prefrontal cortex, the anterior part of the frontal lobes of the brain, to be severed. In the past, this treatment was used for treating mental disorder, psychiatric disorders as a mainstream procedure in some countries. The procedure was controversial from its initial use, in part due to a lack of recognition of the severity and chronicity of severe and enduring psychiatric illnesses, so it was claimed to be an inappropriate treatment. Frontal lobe surgery, including lobotomy, is the second most common surgery for epilepsy to this day, and usually done on one side of the brain, unlike lobotomies for psychiatric disorder which were done on both sides of the brain. The originator of the procedur ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States
The United States of America (U.S.A. or USA), commonly known as the United States (U.S. or US) or America, is a country primarily located in North America. It consists of 50 U.S. state, states, a Washington, D.C., federal district, five major unincorporated territories, nine United States Minor Outlying Islands, Minor Outlying Islands, and 326 Indian reservations. The United States is also in Compact of Free Association, free association with three Oceania, Pacific Island Sovereign state, sovereign states: the Federated States of Micronesia, the Marshall Islands, and the Palau, Republic of Palau. It is the world's List of countries and dependencies by area, third-largest country by both land and total area. It shares land borders Canada–United States border, with Canada to its north and Mexico–United States border, with Mexico to its south and has maritime borders with the Bahamas, Cuba, Russia, and other nations. With a population of over 333 million, it is the List of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Health Service
The National Health Service (NHS) is the umbrella term for the publicly funded healthcare systems of the United Kingdom (UK). Since 1948, they have been funded out of general taxation. There are three systems which are referred to using the "NHS" name (NHS England, NHS Scotland and NHS Wales). Health and Social Care in Northern Ireland was created separately and is often locally referred to as "the NHS". The four systems were established in 1948 as part of major social reforms following the Second World War. The founding principles were that services should be comprehensive, universal and free at the point of delivery—a health service based on clinical need, not ability to pay. Each service provides a comprehensive range of health services, free at the point of use for people ordinarily resident in the United Kingdom apart from dental treatment and optical care. In England, NHS patients have to pay prescription charges; some, such as those aged over 60 and certain state ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nature (journal)
''Nature'' is a British weekly scientific journal founded and based in London, England. As a multidisciplinary publication, ''Nature'' features peer-reviewed research from a variety of academic disciplines, mainly in science and technology. It has core editorial offices across the United States, continental Europe, and Asia under the international scientific publishing company Springer Nature. ''Nature'' was one of the world's most cited scientific journals by the Science Edition of the 2019 '' Journal Citation Reports'' (with an ascribed impact factor of 42.778), making it one of the world's most-read and most prestigious academic journals. , it claimed an online readership of about three million unique readers per month. Founded in autumn 1869, ''Nature'' was first circulated by Norman Lockyer and Alexander Macmillan as a public forum for scientific innovations. The mid-20th century facilitated an editorial expansion for the journal; ''Nature'' redoubled its efforts in ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
