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Patrick Callaerts
Patrick Callaerts is a Belgian molecular biologist and researcher at the Katholieke Universiteit Leuven (Leuven, Belgium). He is head of the '' VIB Laboratory of Developmental Genetics, KU Leuven''. Patrick Callaerts obtained a PhD from the KU Leuven in 1992. He did a Postdoc at the Biozentrum of University of Basel in Switzerland from 1992 until 1997. He was assistant professor at the University of Houston in Houston, Texas United States from 1997 until 2003 and 2004 until 2004. He is VIB Group leader since 2004. His research interest is on gene circuits in Drosophila melanogaster involved in brain development as models for human neurodevelopmental disorders, ranging from transcription Transcription refers to the process of converting sounds (voice, music etc.) into letters or musical notes, or producing a copy of something in another medium, including: Genetics * Transcription (biology), the copying of DNA into RNA, the fir ... factors to effector genes and sign ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Belgium
Belgium, ; french: Belgique ; german: Belgien officially the Kingdom of Belgium, is a country in Northwestern Europe. The country is bordered by the Netherlands to the north, Germany to the east, Luxembourg to the southeast, France to the southwest, and the North Sea to the northwest. It covers an area of and has a population of more than 11.5 million, making it the 22nd most densely populated country in the world and the 6th most densely populated country in Europe, with a density of . Belgium is part of an area known as the Low Countries, historically a somewhat larger region than the Benelux group of states, as it also included parts of northern France. The capital and largest city is Brussels; other major cities are Antwerp, Ghent, Charleroi, Liège, Bruges, Namur, and Leuven. Belgium is a sovereign state and a federal constitutional monarchy with a parliamentary system. Its institutional organization is complex and is structured on both regional ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Katholieke Universiteit Leuven
KU Leuven (or Katholieke Universiteit Leuven) is a Catholic research university in the city of Leuven, Belgium. It conducts teaching, research, and services in computer science, engineering, natural sciences, theology, humanities, medicine, law, canon law, business, and social sciences. In addition to its main campus in Leuven, it has satellite campuses in Kortrijk, Antwerp, Ghent, Bruges, Ostend, Geel, Diepenbeek, Aalst, Sint-Katelijne-Waver, and in Belgium's capital Brussels. KU Leuven is the largest university in Belgium and the Low Countries. In 2017–18, more than 58,000 students were enrolled. Its primary language of instruction is Dutch, although several programs are taught in English, particularly graduate and postgraduate degrees. KU Leuven consistently ranks among the top 100 universities in the world by major ranking tables. As of 2021, it ranks 42nd in the '' Times Higher Education'' rankings, 70th according QS World University Rankings, 87th accordi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Leuven
Leuven (, ) or Louvain (, , ; german: link=no, Löwen ) is the capital and largest City status in Belgium, city of the Provinces of Belgium, province of Flemish Brabant in the Flemish Region of Belgium. It is located about east of Brussels. The municipality itself comprises the historic city and the deelgemeente, former neighbouring municipalities of Heverlee, Kessel-Lo, a part of Korbeek-Lo, Wilsele and Wijgmaal. It is the eighth largest city in Belgium, with more than 100,244 inhabitants. KU Leuven, Belgium's largest university, has its flagship campus in Leuven, which has been a university city since 1425. This makes it the oldest university city in the Low Countries. The city is home of the headquarters of Anheuser-Busch InBev, the world's largest beer brewer and sixth-largest fast-moving consumer goods company. History Middle Ages The earliest mention of Leuven (''Loven'') dates from 891, when a Viking army was defeated by the Franks, Frankish king Arnulf of Carinthia ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Vlaams Instituut Voor Biotechnologie
VIB is a research institute located in Flanders, Belgium. It was founded by the Flemish government in 1995, and became a full-fledged institute on 1 January 1996. The main objective of VIB is to strengthen the excellence of Flemish life sciences research and to turn the results into new economic growth. VIB spends almost 80% of its budget on research activities, while almost 12% is spent on technology transfer activities and stimulating the creation of new businesses, in addition VIB spends approximately 2% on socio-economic activities. VIB is member of EU-LIFE, an alliance of leading life sciences research centres in Europe. The institute is led by Christine Durinx and Jérôme Van Biervliet. Ajit Shetty is chairman of the board of directors. Goals VIB's mission is ''to conduct frontline biomolecular research in life sciences for the benefit of scientific progress and the benefit of society''. The strategic goals of the VIB are: # Strategic basic research # Technology transfer po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
KU Leuven
KU Leuven (or Katholieke Universiteit Leuven) is a Catholic research university in the city of Leuven, Belgium. It conducts teaching, research, and services in computer science, engineering, natural sciences, theology, humanities, medicine, law, canon law, business, and social sciences. In addition to its main campus in Leuven, it has satellite campuses in Kortrijk, Antwerp, Ghent, Bruges, Ostend, Geel, Diepenbeek, Aalst, Sint-Katelijne-Waver, and in Belgium's capital Brussels. KU Leuven is the largest university in Belgium and the Low Countries. In 2017–18, more than 58,000 students were enrolled. Its primary language of instruction is Dutch, although several programs are taught in English, particularly graduate and postgraduate degrees. KU Leuven consistently ranks among the top 100 universities in the world by major ranking tables. As of 2021, it ranks 42nd in the '' Times Higher Education'' rankings, 70th according QS World University Rankings, 87th according to th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Basel
The University of Basel (Latin: ''Universitas Basiliensis'', German: ''Universität Basel'') is a university in Basel, Switzerland. Founded on 4 April 1460, it is Switzerland's oldest university and among the world's oldest surviving universities. The university is traditionally counted among the leading institutions of higher learning in the country. The associated Basel University Library is the largest and among the most important libraries in Switzerland. The university hosts the faculties of theology, law, medicine, humanities and social sciences, science, psychology, and business and economics, as well as numerous cross-disciplinary subjects and institutes, such as the Biozentrum for biomedical research and the Institute for European Global Studies. In 2020, the university had 13,139 students and 378 professors. International students accounted for 27 percent of the student body. In its over 500-year history, the university has been home to Erasmus of Rotterdam, Paracelsu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Houston
The University of Houston (UH) is a Public university, public research university in Houston, Texas. Founded in 1927, UH is a member of the University of Houston System and the List of universities in Texas by enrollment, university in Texas with over 47,000 students. Its campus, which is primarily in southeast Houston, spans , with the inclusion of its Sugar Land and Katy sites. The university is Carnegie Classification of Institutions of Higher Education, classified as an "R1: Doctoral Universities – Very high research activity." The university offers more than 276 degree programs through its 16 academic colleges and schools and an interdisciplinary Honors College - including programs leading to professional degrees in architecture, law, optometry, medicine and pharmacy. The institution spends $203 million annually in research, and operates more than 35 research centers and institutes on campus. Interdisciplinary research includes superconductivity, space commercializatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Houston
Houston (; ) is the List of cities in Texas by population, most populous city in Texas, the Southern United States#Major cities, most populous city in the Southern United States, the List of United States cities by population, fourth-most populous city in the United States, and the List of North American cities by population, sixth-most populous city in North America, with a population of 2,304,580 in 2020. Located in Southeast Texas near Galveston Bay and the Gulf of Mexico, it is the county seat, seat and largest city of Harris County, Texas, Harris County and the principal city of the Greater Houston metropolitan area, which is the fifth-most populous List of metropolitan statistical areas, metropolitan statistical area in the United States and the second-most populous in Texas after Dallas–Fort Worth metroplex, Dallas–Fort Worth. Houston is the southeast anchor of the greater megaregion known as the Texas Triangle. Comprising a land area of , Houston is the List of Uni ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Texas
Texas (, ; Spanish language, Spanish: ''Texas'', ''Tejas'') is a state in the South Central United States, South Central region of the United States. At 268,596 square miles (695,662 km2), and with more than 29.1 million residents in 2020, it is the second-largest U.S. state by both List of U.S. states and territories by area, area (after Alaska) and List of U.S. states and territories by population, population (after California). Texas shares borders with the states of Louisiana to the east, Arkansas to the northeast, Oklahoma to the north, New Mexico to the west, and the Mexico, Mexican States of Mexico, states of Chihuahua (state), Chihuahua, Coahuila, Nuevo León, and Tamaulipas to the south and southwest; and has a coastline with the Gulf of Mexico to the southeast. Houston is the List of cities in Texas by population, most populous city in Texas and the List of United States cities by population, fourth-largest in the U.S., while San Antonio is the second most pop ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the " vinegar fly" or " pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transcription (genetics)
Transcription is the process of copying a segment of DNA into RNA. The segments of DNA transcribed into RNA molecules that can encode proteins are said to produce messenger RNA (mRNA). Other segments of DNA are copied into RNA molecules called non-coding RNAs (ncRNAs). mRNA comprises only 1–3% of total RNA samples. Less than 2% of the human genome can be transcribed into mRNA ( Human genome#Coding vs. noncoding DNA), while at least 80% of mammalian genomic DNA can be actively transcribed (in one or more types of cells), with the majority of this 80% considered to be ncRNA. Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. Transcription proceeds in the following general steps: # RNA polymerase, together with one or more general transcription factors, binds to promot ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Signaling Pathway
In biology, cell signaling (cell signalling in British English) or cell communication is the ability of a cell to receive, process, and transmit signals with its environment and with itself. Cell signaling is a fundamental property of all cellular life in prokaryotes and eukaryotes. Signals that originate from outside a cell (or extracellular signals) can be physical agents like mechanical pressure, voltage, temperature, light, or chemical signals (e.g., small molecules, peptides, or gas). Cell signaling can occur over short or long distances, and as a result can be classified as autocrine, juxtacrine, intracrine, paracrine, or endocrine. Signaling molecules can be synthesized from various biosynthetic pathways and released through passive or active transports, or even from cell damage. Receptors play a key role in cell signaling as they are able to detect chemical signals or physical stimuli. Receptors are generally proteins located on the cell surface or within the inter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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